Find Research Outputs

Search keyword concepts
Selected filters

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010

Author

  • Moustapha Kassem
2019

Absence of an osteopetrosis phenotype in IKBKG (NEMO) mutation-positive women: A case-control study

Frost, M., Tencerova, M., Andreasen, C. M., Levin Andersen, T., Ejersted, C. A., Svaneby, D., Kassem, M., Whyte, M. P. & Frederiksen, A. L., Apr 2019, In : Bone. 121, p. 243-254

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
60 Downloads (Pure)

Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells

Nehlin, J. O., Jafari, A., Tencerova, M. & Kassem, M., 1. Jun 2019, In : Bone. 123, p. 265-273

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
24 Downloads (Pure)

A simple and reliable protocol for long-term culture of murine bone marrow stromal (mesenchymal) stem cells that retained their in vitro and in vivo stemness in long-term culture

Abdallah, B. M., Alzahrani, A. M., Abdel-Moneim, A. M., Ditzel, N. & Kassem, M., Feb 2019, In : Biological Procedures Online. 21, 11 p., 3.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
164 Downloads (Pure)

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation

El-Safadi, M., Shinwari, T., Al-Malki, S., Manikandan, M., Mahmood, A., Aldahmash, A., Alfayez, M., Kassem, M. & Alajez, N. M., 21. Mar 2019, In : Scientific Reports. 9, 13 p., 4977.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
167 Downloads (Pure)

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors

Al-Toub, M., Almohawes, M., Vishnubalaji, R., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 2019, In : Cell Death Discovery. 5, 9 p., 87.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
107 Downloads (Pure)

Efficacy of Injection of Freshly Collected Autologous Adipose Tissue Into Perianal Fistulas in Patients With Crohn's Disease

Dige, A., Hougaard, H. T., Agnholt, J., Pedersen, B. G., Tencerova, M., Kassem, M., Krogh, K. & Lundby, L., 1. Jun 2019, In : Gastroenterology. 156, 8, p. 2208-2216.e1

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
50 Downloads (Pure)

ESTABLISHMENT OF A KNOCKDOWN MODEL FOR UNRAVELLING THE PATHOGENESIS OF MANTLE CELL LYMPHOMA

Valentin Hansen, S., Cédile, O., Hansen, M. C., Christensen, J. H., Chen, L., Kassem, M., Abildgaard, N. & Nyvold, C. G., Jun 2019.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells

Almuraikhi, N., Almasoud, N., Binhamdan, S., Younis, G., Ali, D., Manikandan, M., Vishnubalaji, R., Atteya, M., Siyal, A., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 21. Nov 2019, In : Stem Cells International. 2019, 12 p., 3435901.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
36 Downloads (Pure)

Identification of novel factors involved in the coupling of bone resorption and bone formation in humans reveals RANKL/DPP4 as a new link between bone remodeling and energy metabolism

Weivoda, M., Chew, C. K., Monroe, D., Atkinson, E., Farr, J., Thicke, B., Ruan, M., Tweed, A., Eckhardt, B., McCready, L., Geske, J., Rizza, R., Vella, A., Matveyenko, A., Drake, M., Clarke, B., Oursler, M. J., Khosla, S., Kassem, M. & Andersen, T., Dec 2019, In : Journal of Bone and Mineral Research. 34, Suppl. 1, p. 18 1 p., 1051.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Insulin Signaling in Bone Marrow Adipocytes

Tencerova, M., Okla, M. & Kassem, M., Dec 2019, In : Current Osteoporosis Reports (Print). 17, 6, p. 446-454

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
36 Downloads (Pure)

In Vitro and In Vivo Evaluation of 1-(3 Dimethylaminopropyl)-3-Ethyl Carbodiimide (EDC) Cross-Linked Gum Arabic–Gelatin Composite as an Ideal Porous Scaffold for Tissue Engineering

Edwin, B. T., Dhanya, H., Nair, P. D. & Kassem, M., 2019, Biomaterials in Orthopaedics and Bone Regeneration: Design and Synthesis. Bains, P. S., Sidhu, S. S., Bahraminasab, M. & Prakash, C. (eds.). Springer, p. 131-145 (Materials Horizons: From Nature to Nanomaterials ).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment

Chen, L., Shi, K., Andersen, T. L., Qiu, W. & Kassem, M., 12. Feb 2019, In : Cell Death and Disease. 10, 2, p. 1-13 126.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
130 Downloads (Pure)

Lansoprazole inhibits the cysteine protease legumain by binding to the active site

Bosnjak, T., Solberg, R., Hemati, P. D., Jafari, A., Kassem, M. & Johansen, H. T., Aug 2019, In : Basic & Clinical Pharmacology & Toxicology. 125, 2, p. 89-99

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
35 Downloads (Pure)

Mesenchymal stem cells isolated from both distal femurs of patients with unilateral trauma or osteoarthritis of the knee exhibit similar in-vitro ability of bone formation

Falster, C., Poulsen, S. S., Storaas, A. M., Schroeder, H. M., Vinther, J. H., Kassem, M. & Joergensen, U., 1. Sep 2019, In : Journal of Orthopaedic Science. 24, 5, p. 918-924

Research output: Contribution to journalJournal articleResearchpeer-review

Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

Tencerova, M., Rendina-Ruedy, E., Neess, D., Færgeman, N., Figeac, F., Ali, D., Danielsen, M., Haakonsson, A., Rosen, C. J. & Kassem, M., 1. Dec 2019, In : Bone Research. 7, 14 p., 35.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
76 Downloads (Pure)

Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B

Vishnubalaji, R., Elango, R., Al-Toub, M., Manikandan, M., Al-Rikabi, A., Harkness, L., Ditzel, N., Atteya, M., Hamam, R., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 1. Dec 2019, In : Scientific Reports. 9, 14 p., 8101.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
121 Downloads (Pure)

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

Almuraikhi, N., Ali, D., Vishnubalaji, R., Manikandan, M., Atteya, M., Siyal, A., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 22. Aug 2019, In : Stem Cells International. 2019, 13 p., 3041262.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
85 Downloads (Pure)
Open Access
File
161 Downloads (Pure)

Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

Rauch, A., Haakonsson, A. K., Madsen, J. G. S., Larsen, M., Forss, I., Madsen, M. R., Van Hauwaert, E. L., Wiwie, C., Jespersen, N. Z., Tencerova, M., Nielsen, R., Larsen, B. D., Röttger, R., Baumbach, J., Scheele, C., Kassem, M. & Mandrup, S., Apr 2019, In : Nature Genetics. 51, 4, p. 716-727

Research output: Contribution to journalJournal articleResearchpeer-review

Strontium functionalized scaffold for bone tissue engineering

Prabha, R. D., Nair, B. P., Ditzel, N., Kjems, J., Nair, P. D. & Kassem, M., 1. Jan 2019, In : Materials Science and Engineering C: Biomimetic Materials, Sensors and Systems. 94, p. 509-515

Research output: Contribution to journalJournal articleResearchpeer-review

TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1-p38 Signaling

Jafari, A., Isa, A., Chen, L., Ditzel, N., Zaher, W., Harkness, L., Johnsen, H. E., Abdallah, B. M., Clausen, C. & Kassem, M., 1. Mar 2019, In : Stem Cells. 37, 3, p. 407-416

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
88 Downloads (Pure)

Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

Walker, J. V., Zhuang, H., Singer, D., Illsley, C. S., Kok, W. L., Sivaraj, K. K., Gao, Y., Bolton, C., Liu, Y., Zhao, M., Grayson, P. R. C., Wang, S., Karbanová, J., Lee, T., Ardu, S., Lai, Q., Liu, J., Kassem, M., Chen, S., Yang, K. & 7 others, Bai, Y., Tredwin, C., Zambon, A. C., Corbeil, D., Adams, R., Abdallah, B. M. & Hu, B., 9. Aug 2019, In : Nature Communications. 10, 1, 18 p., 3596.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
87 Downloads (Pure)
2018

Actin depolymerization enhances adipogenic differentiation in human stromal stem cells

Chen, L., Hu, H., Qiu, W., Shi, K. & Kassem, M., 1. May 2018, In : Stem Cell Research. 29, p. 76-83

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
230 Downloads (Pure)

Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice

Figeac, F., Andersen, D. C., Nipper Nielsen, C. A., Ditzel, N., Sheikh, S. P., Skjødt, K., Kassem, M., Jensen, C. H. & Abdallah, B. M., May 2018, In : Bone. 110, p. 312-320

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
182 Downloads (Pure)

Bioactive Nano-fibrous Scaffold for Vascularized Craniofacial Bone Regeneration

Prabha, R. D., Kraft, D. C. E., Harkness, L., Melsen, B., Varma, H., Nair, P. D., Kjems, J. & Kassem, M., Mar 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 3, p. e1537-e1548

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
139 Downloads (Pure)

Clinical improvement in a patient with monostotic melorheostosis after treatment with denosumab: a case report

Byberg, S., Abrahamsen, B., Kassem, M., Ralston, S. & Schwarz, P., 27. Sep 2018, In : Journal of Medical Case Reports. 12, 6 p., 278.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
143 Downloads (Pure)

Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions

Schmal, H., Kowal, J. M., Kassem, M., Seidenstuecker, M., Bernstein, A., Böttiger, K., Xiong, T., Südkamp, N. P. & Kubosch, E. J., 1. Jan 2018, In : Stem Cells International. 2018, 12 p., 4142031.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
177 Downloads (Pure)

Composites of fatty acids and ceramic powders are versatile biomaterials for personalized implants and controlled release of pharmaceuticals

Bonde Jensen, M., Slots, C., Ditzel, N., Albrektsen, O., Wiatr Borg, S., Thygesen, T., Kassem, M. & Andersen, M. Ø., Jun 2018, In : Bioprinting. 10, e00027.

Research output: Contribution to journalJournal articleResearchpeer-review

Detection of differential protein expression patterns in osteogenic and adipogenic lineages of bone marrow derived stromal (mesenchymal) stem cells

Facchinetti, G., Rozanova, S., Kowal, J., Kassem, M., Gemoll, T. & Habermann, J., 2018, In : Oncology Research and Treatment. 41, Suppl. 1, p. 125 1 p.

Research output: Contribution to journalConference abstract in journalResearch

Open Access
File
66 Downloads (Pure)

Establishing lobular-like and interlobular-like fibroblast cell lines from human breast reduction mammoplasties

Morsing, M., Jafari, A., Kassem, M., Petersen, O. W. & Ronnov-Jessen, L., Jul 2018, In : Cancer research. 78, Suppl. 13, 1010.

Research output: Contribution to journalConference abstract in journalResearch

Global MicroRNA Profiling in Human Bone Marrow Skeletal-Stromal or Mesenchymal-Stem Cells Identified Candidates for Bone Regeneration

Chang, C-C., Venø, M. T., Chen, L., Ditzel, N., Le, D. Q. S., Dillschneider, P., Kassem, M. & Kjems, J., 7. Feb 2018, In : Molecular Therapy. 26, 2, p. 593-605

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
143 Downloads (Pure)

High-Fat Diet-Induced Obesity Promotes Expansion of Bone Marrow Adipose Tissue and Impairs Skeletal Stem Cell Functions in Mice

Tencerova, M., Figeac, F., Ditzel, N., Taipaleenmäki, H., Nielsen, T. K. & Kassem, M., Jun 2018, In : Journal of Bone and Mineral Research. 33, 6, p. 1154-1165

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
216 Downloads (Pure)

Induction of quiescence (G0) in bone marrow stromal stem cells enhances their stem cell characteristics

Rumman, M., Majumder, A., Harkness, L., Venugopal, B., Vinay, M. B., Pillai, M. S., Kassem, M. & Dhawan, J., Jul 2018, In : Stem Cell Research. 30, p. 69-80

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
172 Downloads (Pure)

International Harmonization and Standardization between Denmark and Germany: The German-Danish Interreg project BONEBANK

Maushagen, R., Gemoll, T., Oberlaender, M., Faccinetti, G., Figge, L., Kock-Schoppenhauer, A-K., Duhm-Harbeck, P., Niessen, L., Unger, A., Wendlandt, R., Kowal, J. M., Haakonsson, A. K., Bober, C., Diercks, K., Nassutt, R., Buescher, R., Reimers, N., Schmal, H., Frahm, T., Eckers, A. & 5 others, Brilling, J., Barington, T., Kassem, M., Schulz, A-P. & Habermann, J. K., 31. Jul 2018.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Leif Mosekilde IN MEMORIAM

Rejnmark, L., Brixen, K., Kassem, M., Hermann, P., Vestergaard, P., Eriksen, E. F., Bollerslev, J., Nielsen, H. K., Charles, P. & Langdahl, B., Nov 2018, In : Journal of Bone and Mineral Research. 33, 11, 1 p.

Research output: Contribution to journalJournal articleCommunication

Lower Insulin Sensitivity in Patients With High Bone Mass due to a LRP5T253I mutation

Lauterlein, J-J. L., Hermann, A. P., Kassem, M., Hojlund, K. & Frost, M., 1. Nov 2018, In : Journal of Bone and Mineral Research. 33, Suppl. 1, p. 40 1 p.

Research output: Contribution to journalConference abstract in journalResearch

Molecular Phenotyping of Telomerized Human Bone Marrow Skeletal Stem Cells Reveals a Genetic Program of Enhanced Proliferation and Maintenance of Differentiation Responses

Twine, N. A., Harkness, L., Adjaye, J., Aldahmash, A., Wilkins, M. R. & Kassem, M., Sep 2018, In : JBMR Plus. 2, 5, p. 257-267

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
150 Downloads (Pure)

Molecular profiling of ALDH1+ colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress prosurvival signalling pathways

Vishnubalaji, R., Manikandan, M., Fahad, M., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Alajez, N. M., 2. Mar 2018, In : OncoTarget. 9, 17, p. 13551-13564

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
220 Downloads (Pure)

Multiple intracellular signaling pathways orchestrate adipocytic differentiation of human bone marrow stromal stem cells

Ayesh Hafez Ali, D., Abuelreich, S., Alkeraishan, N., Shwish, N. B., Hamam, R., Kassem, M., Alfayez, M., Aldahmash, A. & Alajez, N. M., 30. Jan 2018, In : Bioscience Reports. 38, 1, 10 p., BSR20171252.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
168 Downloads (Pure)

NR2F1 mediated down-regulation of osteoblast differentiation was rescued by bone morphogenetic protein-2 (BMP-2) in human MSC

Manikandan, M., Abuelreich, S., Elsafadi, M., Alsalman, H., Almalak, H., Siyal, A., Hashmi, J. A., Aldahmash, A., Kassem, M., Alfayez, M. & Mahmood, A., 1. Nov 2018, In : Differentiation. 104, p. 36-41

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
97 Downloads (Pure)

Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

Ali, D., Chalisserry, E. P., Manikandan, M., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Alajez, N. M., 2018, In : Stem Cells International. 2018, 12 p., 2379546.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
125 Downloads (Pure)

Secreted Clusterin protein inhibits osteoblast differentiation of bone marrow mesenchymal stem cells by suppressing ERK1/2 signaling pathway

Abdallah, B., Alzahrani, A. M. & Kassem, M., May 2018, In : Bone. 110, p. 221-229

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
169 Downloads (Pure)

Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells

AlMuraikhi, N., Ali, D., Alshanwani, A., Vishnubalaji, R., Manikandan, M., Atteya, M., Siyal, A., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 21. Nov 2018, In : Stem Cell Research & Therapy. 9, 10 p., 319.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
150 Downloads (Pure)

TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton

Elsafadi, M., Manikandan, M., Almalki, S., Mobarak, M., Atteya, M., Iqbal, Z., Hashmi, J. A., Shaheen, S., Alajez, N., Alfayez, M., Kassem, M., Dawud, R. A. & Mahmood, A., 2018, In : Stem Cells International. 2018, 14 p., 6913594.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
161 Downloads (Pure)
2017

Bone and Skeletal Stem Cells are Affected in High Fat Diet Mice

Figeac, F., Tencerova, M., Ditzel, N., Nielsen, T. K. L., Jørgensen, B. & Kassem, M., 2017. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Bone morphology in IKBKG (NEMO) mutation positive women: A case-control study

Frost, M., Tencerova, M., Ejersted, C. A., Svaneby, D., Levin Andersen, T., Kassem, M., McAlister, W. H., Novack, D., Whyte, M. P. & Frederiksen, A. L., 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Bone morphology in IKBKG (NEMO) mutation positive women: A case-control study

Frost, M., Tencerova, M., Ejersted, C. A., Svaneby, D., Levin Andersen, T., Kassem, M., McAlister, W. H., Novack, D. V., Whyte, M. P. & Frederiksen, A. L., Dec 2017, In : Journal of Bone and Mineral Research. 32, S1, p. S395 1 p., MO0710.

Research output: Contribution to journalConference abstract in journalResearchpeer-review