Find Research Outputs

Search keyword concepts
Selected filters

Publication Year

  • 2019
  • 2017
  • 2016
  • 2015

Author

  • Martin Røssel Larsen
2016

Phosphopeptide enrichment by immobilized metal affinity chromatography

Thingholm, T. E. & Larsen, M. R., 2016, Phospho-Proteomics: Methods and Protocols. von Stechow, L. (ed.). 2. ed. Humana Press, p. 123-133 (Methods in Molecular Biology, Vol. 1355).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Improving the Phosphoproteome Coverage for Limited Sample Amounts Using TiO2-SIMAC-HILIC (TiSH) Phosphopeptide Enrichment and Fractionation

Engholm-Keller, K. & Larsen, M. R., 2016, Phospho-Proteomics : Methods and Protocols. Stechow, L. V. (ed.). 2. ed. Springer, Vol. Part III. p. 161-177 (Methods in Molecular Biology, Vol. 1335).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2017

Characterization of the phosphoproteome and sialoproteome in brain tissues by mass spectrometry

Ibáñez-Vea, M., Kempf, S. J. & Larsen, M. R., 2017, Current Proteomic Approaches Applied to Brain Function. Santamaría, E. & Fernández-Irigoyen, J. (eds.). Humana Press, p. 191-206 (Neuromethods, Vol. 127).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2016

High-performance hybrid Orbitrap mass spectrometers for quantitative proteome analysis: Observations and implications

Williamson, J. C., Edwards, A. V. G., Verano-Braga, T., Schwämmle, V., Kjeldsen, F., Jensen, O. N. & Larsen, M. R., Mar 2016, In : Proteomics. 16, 6, p. 907-914

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Elucidation of altered pathways in tumor-initiating cells of triple-negative breast cancer: A useful cell model system for drug screening

Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, J. B., Moreira, J. M. A., Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., Aug 2017, In : Stem Cells. 35, 8, p. 1898–1912

Research output: Contribution to journalJournal articleResearchpeer-review

2019

Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets following Euglycemia

Kang, T., Boland, B. B., Alarcon, C., Grimsby, J. S., Rhodes, C. J. & Larsen, M. R., 6. Sep 2019, In : Journal of Proteome Research. 18, 9, p. 3245-3258

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Understanding Alzheimer's disease by global quantification of protein phosphorylation and sialylated N-linked glycosylation profiles: A chance for new biomarkers in neuroproteomics?

Lassen, P. S., Thygesen, C., Larsen, M. R. & Kempf, S. J., 2017, In : Journal of Proteomics. 161, May, p. 11-25

Research output: Contribution to journalReviewResearchpeer-review

Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi

Alves, M. J. M., Kawahara, R., Viner, R., Colli, W., Mattos, E. C., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 16. Jan 2017, In : Journal of Proteomics. 151, p. 182-192

Research output: Contribution to journalJournal articleResearchpeer-review

"Highly increased expression of astrocytic cytokine in neocortex of Alzheimer’s patients investigated by proteomics"

Thygesen, C., Kempf, S., Metaxas, A., Darvesh, S., Larsen, M. R. & Finsen, B., 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

2019

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

Nixon, B., De Iuliis, G. N., Hart, H. M., Zhou, W., Mathe, A., Bernstein, I., Anderson, A. L., Stanger, S. J., Skerrett-Byrne, D. A., Jamaluddin, M. F. B., Almazi, J. G., Bromfield, E. G., Larsen, M. R. & Dun, M. D., 15. Mar 2019, In : Molecular and Cellular Proteomics. 18, Suppl. 1, p. S91-S108

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
166 Downloads (Pure)
2016

The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer

Hartung, A-M., Swensen, J., Uriz, I. E., Kristjansdottir, K., Petersen, U. S. S., Bang, J. M. V., Guerra, B., Andersen, H. S., Dobrowolski, S. F., Carey, J. C., Yu, P., Vaughn, C., Calhoun, A., Larsen, M. R., Dyrskjøt, L., Stevenson, D. A. & Andresen, B. S., 2016, In : P L o S Genetics. 12, 5, p. e1006039

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
161 Downloads (Pure)
2015

Proteotranscriptomic profiling of 231-BR breast cancer cells: Identification of potential biomarkers and therapeutic targets for brain metastasis

Dun, M. D., Chalkley, R. J., Faulkner, S., Keene, S., Avery-Kiejda, K. A., Scott, R. J., Falkenby, L. G., Cairns, M. J., Larsen, M. R., Bradshaw, R. A. & Hondermarck, H., 2015, In : Molecular and Cellular Proteomics. 14, 9, p. 2316-2330

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
117 Downloads (Pure)

Optimization of calmodulin-affinity chromatography for brain and organelles

Kulej, K., Sidoli, S., Palmisano, G., Edwards, A. V. G., Robinson, P. J. & Larsen, M. R., 2015, In : EuPA Open Proteonomics. 8, p. 55-67

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
197 Downloads (Pure)
2016

The use of titanium dioxide for selective enrichment of phosphorylated peptides

Thingholm, T. E. & Larsen, M. R., 2016, Phospho-Proteomics: Methods and Protocols. von Stechow, L. (ed.). Humana Press, p. 135-146 (Methods in Molecular Biology, Vol. 1355).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer

Mereiter, S., Magalhães, A., Adamczyk, B., Jin, C., Almeida, A., Drici, L., Ibáñez-Vea, M., Gomes, C., Ferreira, J. A., Afonso, L. P., Santos, L. L., Larsen, M. R., Kolarich, D., Karlsson, N. G. & Reis, C. A., Aug 2016, In : BBA Reviews on Cancer. 1860, 8, p. 1795-1808

Research output: Contribution to journalJournal articleResearchpeer-review

2017

GLYCOSYLATED YGHJ POLYPEPTIDES FROM ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC)

Boysen, A., Møller-Jensen, J., Palmisano, G. & Larsen, M. R., 13. Apr 2017, Patent No. WO2017059864 (A1), 13. Apr 2017, Priority date 6. Oct 2015, Priority No. EP20150188608

Research output: Patent

2019

Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke

Thygesen, C., Larsen, M. R. & Finsen, B., Jul 2019, In : Expert Review of Proteomics. 16, 7, p. 601-611

Research output: Contribution to journalReviewResearchpeer-review

2015

Quantitative proteomics analysis of platelet-derived microparticles reveals distinct protein signatures when stimulated by different physiological agonists

Milioli, M., Vea, M. I., Sidoli, S., Palmisano, G., Careri, M. & Larsen, M. R., 2015, In : Journal of Proteomics. 121, p. 56-66

Research output: Contribution to journalJournal articleResearchpeer-review

2016

CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility

Young, S. A. M., Miyata, H., Satouh, Y., Muto, M., Larsen, M. R., Aitken, R. J., Baker, M. A. & Ikawa, M., Dec 2016, In : Reproduction. 152, 6, p. 665-672

Research output: Contribution to journalJournal articleResearchpeer-review

2019

Proteomics insights into the responses of Saccharomyces cerevisiae during mixed-culture alcoholic fermentation with Lachancea thermotolerans

Peng, C., Andersen, B., Arshid, S., Larsen, M. R., Albergaria, H., Lametsch, R. & Arneborg, N., Sep 2019, In : FEMS Microbiology Ecology. 95, 9, 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2016

Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4

Mereiter, S., Magalhães, A., Adamczyk, B., Jin, C., Almeida, A., Drici, L., Ibáñez-Vea, M., Larsen, M. R., Kolarich, D., Karlsson, N. G. & Reis, C. A., Jun 2016, In : Data in Brief. 7, p. 814-833

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
149 Downloads (Pure)
2017

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

Jensen, P., Myhre, C. L., Lassen, P., Metaxas, A., Khan, A. M., Lambertsen, K. L., Babcock, A., Finsen, B., Larsen, M. R. & Kempf, S., 2017, In : OncoTarget. 8, 36, p. 60223-60242

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
327 Downloads (Pure)
2016

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

Kempf, S. J., Metaxas, A., Ibáñez-Vea, M., Darvesh, S., Finsen, B. & Larsen, M. R., 7. Jun 2016, In : Oncotarget. 7, 23, p. 33627-33648

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
202 Downloads (Pure)
2015

Unraveling incompatibility between wheat and the fungal pathogen Zymoseptoria tritici through apoplastic proteomics

Yang, F., Li, W., Derbyshire, M., Larsen, M. R., Rudd, J. J. & Palmisano, G., 2015, In : BMC Genomics. 16, 1, 12 p., 368.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
93 Downloads (Pure)
2019

Zika virus impairs neurogenesis and synaptogenesis pathways in human neural stem cells and neurons

Rosa-Fernandes, L., Cugola, F. R., Russo, F. B., Kawahara, R., de Melo Freire, C. C., Leite, P. E. C., Bassi Stern, A. C., Angeli, C. B., de Oliveira, D. B. L., Melo, S. R., Zanotto, P. M. D. A., Durigon, E. L., Larsen, M. R., Beltrão-Braga, P. C. B. & Palmisano, G., 15. Mar 2019, In : Frontiers in cellular neuroscience. 13, 16 p., 64.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
137 Downloads (Pure)
2017

Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway

Müller, A. H., Edwards, A. V. G., Larsen, M. R., Nielsen, J., Warfvinge, K., Povlsen, G. K. & Edvinsson, L., 2017, In : Journal of Molecular Neuroscience. 62, 3-4, p. 380-394

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
153 Downloads (Pure)
2016

Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model

Kempf, S. J., Janik, D., Barjaktarovic, Z., Braga-Tanaka III, I., Tanaka, S., Neff, F., Saran, A., Larsen, M. R. & Tapio, S., 2016, In : OncoTarget. 7, 44, p. 71817-71832

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
193 Downloads (Pure)

Proteomic identification of putative microRNA394 target genes in Arabidopsis thaliana identifies major latex protein family members critical for normal development

Litholdo, C. G., Parker, B., Eamens, A. L., Larsen, M. R., Cordwell, S. & Waterhouse, P. M., Jun 2016, In : Molecular and Cellular Proteomics. 15, 6, p. 2033-2047

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
124 Downloads (Pure)
2019

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Metaxas, A., Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S., Brooks, D. J., Larsen, M. R. & Finsen, B., 31. Oct 2019, In : Scientific Reports. 9, 1, 15 p., 15758.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
69 Downloads (Pure)
2015

Characterization of human neural differentiation from pluripotent stem cells using proteomics/PTMomics: current state-of-the-art and challenges

Braga, M. N. D. M., Meyer, M., Zeng, X. & Larsen, M. R., 2015, In : Proteomics. 15, 4, p. 656-74

Research output: Contribution to journalJournal articleResearchpeer-review

2019

Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

Bogetofte, H., Jensen, P., Okarmus, J., Schmidt, S. I., Agger, M., Ryding, M., Nørregaard, P., Fenger, C., Zeng, X., Graakjær, J., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., Dec 2019, In : Neurobiology of Disease. 132, 14 p., 104581.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
109 Downloads (Pure)

PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

Bogetofte Thomasen, H., Jensen, P., Ryding, M. A. J. G., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M., Azevedo, C., Roybon, L., Bak, L. K., Waagepetersen, H. S., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 5. Jul 2019, In : Frontiers in Cellular Neuroscience. 13, 14 p., 297.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
99 Downloads (Pure)

Cellular and molecular abnormalities in brain organoids derived from autistic patients

Ilieva, M., Kamand, M., Forsberg, S. L., Larsen, M. R. & Tanja, M., Dec 2019, In : European Neuropsychopharmacology. 29, Suppl. 6, p. S359-S360 P.510.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

2015

Important options available - from start to finish -for translating proteomics results to clinical chemistry

Heegaard, N. H. H., Ostergaard, O., Bahl, J. M. C., Overgaard, M., Beck, H. C., Rasmussen, L. M. & Larsen, M. R., 2015, In : Proteomics - Clinical Applications. 9, 1-2, p. 235-252

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Novel DNA coding regions and protein arginylation reveal unexplored T. cruzi proteome and PTMs

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Avila, C. C., Larsen, M. R., Pereira Alves, J. M. & Palmisano, G., 2017, In : International Journal of Mass Spectrometry. 418, p. 51-66

Research output: Contribution to journalJournal articleResearchpeer-review

2015

Automated N-glycan profiling of a mutant Trypanosoma rangeli sialidase expressed in Pichia pastoris, using tandem mass spectrometry and bioinformatics

Li, H., Rasmussen, M. I., Larsen, M. R., Guo, Y., Jers, C., Palmisano, G., Mikkelsen, J. D. & Kirpekar, F., Dec 2015, In : Glycobiology. 25, 12, p. 1350-1361

Research output: Contribution to journalJournal articleResearchpeer-review

2016

Sequential elution from IMAC (SIMAC): An efficient method for enrichment and separation of mono-and multi-phosphorylated peptides

Thingholm, T. E. & Larsen, M. R., 2016, Phospho-Proteomics: Methods and Protocols. von Stechow, L. (ed.). Humana Press, p. 147-160 (Methods in Molecular Biology, Vol. 1355).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2015

Quantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes and Lower Levels among Metformin Users

Rørdam Preil, S., Kristensen, L. P., Beck, H. C., Jensen, P. S., Nielsen, P. S., Steiniche, T., Bjørling-Poulsen, M., Larsen, M. R., Hansen, M. L. & Rasmussen, L. M., 14. Sep 2015, In : Circulation: Cardiovascular Genetics. 8, p. 727-35

Research output: Contribution to journalJournal articleResearchpeer-review

GLYCOSYLATED POLYPEPTIDES ORIGINATING FROM ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC): -

Boysen, A., Møller-Jensen, J., Palmisano, G. & Larsen, M. R., 15. Oct 2015, IPC No. A61K 39/108 (2006.01), Patent No. WO/2015/154783, Priority date 10. Apr 2014, Priority No. PCT/DK2015/050089

Research output: Patent

2019

A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells

Billing, A. M., Dib, S. S., Bhagwat, A. M., da Silva, I. T., Drummond, R. D., Hayat, S., Al-Mismar, R., Ben-Hamidane, H., Goswami, N., Engholm-Keller, K., Larsen, M. R., Suhre, K., Rafii, A. & Graumann, J., 1. Oct 2019, In : Molecular and Cellular Proteomics. 18, 10, p. 1950-1966

Research output: Contribution to journalJournal articleResearchpeer-review

2016

A novel mass spectrometric strategy "BEMAP" reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli

Boysen, A., Palmisano, G., Krogh, T. J., Duggin, I. G., Larsen, M. R. & Møller-Jensen, J., 26. Aug 2016, In : Scientific Reports. 6, 13 p., 32016.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
145 Downloads (Pure)
2015

The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2

Roux, M. E., Rasmussen, M. W., Palma, K., Lolle, S., Regue, A. M., Bethke, G., Glazebrook, J., Zhang, W. P., Sieburth, L., Larsen, M. R., Mundy, J. & Petersen, M., 2015, In : E M B O Journal. 34, 5, p. 593-608

Research output: Contribution to journalJournal articleResearchpeer-review

2016

Detection of proteolytic signatures for Parkinson's disease

Jordal, P. L., Dyrlund, T. F., Winge, K., Larsen, M. R., Danielsen, E. H., Wells, J. A., Otzen, D. E. & Enghild, J. J., 1. Feb 2016, In : Future Neurology. 11, 1, p. 15-32

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

Jacobsen, K., Bertran-Alamillo, J., Molina, M. A., Teixidó, C., Karachaliou, N., Pedersen, M. H., Castellví, J., Garzón, M., Codony-Servat, C., Codony-Servat, J., Giménez-Capitán, A., Drozdowskyj, A., Viteri, S., Larsen, M. R., Lassen, U., Felip, E., Bivona, T. G., Ditzel, H. J. & Rosell, R., 1. Dec 2017, In : Nature Communications. 8, 14 p., 410.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
216 Downloads (Pure)
2019

Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria

Kawahara, R., Rosa-Fernandes, L., Dos Santos, A. F., Bandeira, C. L., Dombrowski, J. G., Souza, R. M., da Fonseca, M. P., Festuccia, W. T., Labriola, L., Larsen, M. R., Marinho, C. R. F. & Palmisano, G., 1. Feb 2019, In : Molecular and Cellular Proteomics. 18, 2, p. 182-199

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
107 Downloads (Pure)
2016

Simultaneous enrichment of cysteine-containing peptides and phosphopeptides using a cysteine-specific phosphonate adaptable tag (CysPAT) in combination with titanium dioxide (TiO2) chromatography

Huang, H., Pedersen, M. H., Ibañez-Vea, M., Lassen, P. S., Larsen, M. R. & Palmisano, G., 2016, In : Molecular and Cellular Proteomics. 15, 10, p. 3282-3296

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
173 Downloads (Pure)
2017

Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat

Spray, S., Johansson, S. E., Edwards, A. V. G., Larsen, M. R., Radziwon-Balicka, A., Povlsen, G. K. & Edvinsson, L., 2017, In : Journal of Molecular Neuroscience. 61, 3, p. 396–411

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
148 Downloads (Pure)
2016

The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish

Berchtold, M. W., Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, T., Chen, J-N., Larsen, M. R. & la Cour, J. M., 23. Dec 2016, In : Journal of Biological Chemistry. 291, 52, p. 26636-26646

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
159 Downloads (Pure)
2019

First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus

Ravnsborg, T., Svaneklink, S., Andersen, L. L. T., Larsen, M. R., Jensen, D. M. & Overgaard, M., 27. Mar 2019, In : PLOS ONE. 14, 3, 13 p., e0214457.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
175 Downloads (Pure)