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3',4'-trans-Linked bicyclic nucleosides locked in S-type conformations

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Abstract

A novel class of 3′,4′-trans-linked bicyclic nucleosides with locked S-type furanose conformations is introduced by synthesis of two model derivatives; one was obtained by cyclic ether formation and the other by ring-closing metathesis methodology.

Original languageEnglish
JournalChemical Communications
Volume2002
Issue number17
Pages (from-to)1888-1889
ISSN1359-7345
DOIs
Publication statusPublished - 2002

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