1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment

André Faldt; Heidi Lopez De Diego; Rene Holm

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment

André Faldt (Inventor), Heidi Lopez De Diego (Inventor), Rene Holm (Inventor)

Research output: Patent

Abstract

1-[2-(2,4-dimethylphenylsulphanyl)phenyl)]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.

Original language	English
IPC	C07D 295/ 096 A I
Patent number	US2017360777
Country/Territory	Denmark
Priority date	10/08/2017
Priority number	US201715674043
Publication status	Published - 21. Dec 2017
Externally published	Yes

Cite this

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title = "1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment",

abstract = "1-[2-(2,4-dimethylphenylsulphanyl)phenyl)]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.",

author = "Andr{\'e} Faldt and {De Diego}, {Heidi Lopez} and Rene Holm",

year = "2017",

month = dec,

day = "21",

language = "English",

type = "Patent",

note = "US2017360777; C07D 295/ 096 A I",

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T1 - 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment

AU - Faldt, André

AU - De Diego, Heidi Lopez

AU - Holm, Rene

PY - 2017/12/21

Y1 - 2017/12/21

N2 - 1-[2-(2,4-dimethylphenylsulphanyl)phenyl)]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.

AB - 1-[2-(2,4-dimethylphenylsulphanyl)phenyl)]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.

M3 - Patent

M1 - US2017360777

ER -

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment

Abstract

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