Project Details
Description
New land winnings in microscopy introducing super-resolution techniques makes it possible to visualize how proteins and lipids interacts in the mammalian plasma membrane. Recent evidence for membrane lipids organizing in nano-domains suggest they have a regulatory role. The project aims to develop new techniques and analysis methods to image position, interaction and transport over the membrane by lipids and proteins. The grant funds 1 PhD student, 2 postdocs and equipment.
| Status | Finished |
|---|---|
| Effective start/end date | 21/12/2017 → 31/05/2023 |
Funding
- Villum Foundation: DKK8,076,450.00
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Related research output
- 10 Journal article
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4-oxo-2-nonenal-induced α-synuclein oligomers interact with membranes in the cell, leading to mitochondrial fragmentation
Andersen, C., Lausdahl, A. K., Nielsen, J., Clausen, M. P., Mulder, F. A. A., Otzen, D. E. & Arnspang, E. C., 15. Aug 2023, In: Biochemistry. 62, 16, p. 2417–2425Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile245 Downloads (Pure) -
Angiotensin II Treatment Induces Reorganization and Changes in the Lateral Dynamics of Angiotensin II Type 1 Receptor in the Plasma Membrane Elucidated by Photoactivated Localization Microscopy Combined with Image Spatial Correlation Analysis
Andersen, C., Zulueta Díaz, Y. D. L. M., Lavrsen Kure, J., Eriksen, M. H., Lovatt, A. L., Lagerholm , C., Morales , S., Sehayek , S., Sheard , T. M. D., Wiseman , P. W. & Arnspang, E. C., 17. Jan 2023, In: Analytical Chemistry. 95, 2, p. 730–738Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile168 Downloads (Pure) -
Nuclear Envelope Morphology Change upon Repetitive Treatment with Modified Antisense Oligonucleotides Targeting Hutchinson-Gilford Progeria Syndrome
Abdelrahman, A., Nielsen, M.-M., Stage, M. H. & Arnspang, E. C., Mar 2023, In: Biochemistry and Biophysics Reports. 33, 5 p., 101411.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile93 Downloads (Pure) -
Quantitative image mean squared displacement (iMSD) analysis of the dynamics of Aquaporin 2 within the membrane of live cells
Zulueta Díaz, Y. D. L. M., Lavrsen Kure, J., Grosso, R. A., Andersen, C., Pandzic, E., Sengupta, P., Wiseman, P. W. & Arnspang, E. C., Nov 2023, In: BBA General Subjects. 1867, 11, 130449.Research output: Contribution to journal › Journal article › Research › peer-review
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siRNA Delivery Mediated by pH and Redox Responsive P(DEAEMA-co-HEMA-g-PEGMA) Nanogels
K. Notabi, M., Arnspang, E. C., Peppas, N. & Andersen, M. Ø., Sept 2023, In: Journal of Drug Delivery Science and Technology. 86, 13 p., 104510.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile180 Downloads (Pure)
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