Associate professor - Transcriptional Regulation at Single-Cell Resolution (may change)

Siersbæk, Rasmus (Project manager)
Jakobsen, Simon Toftholm (Postdoc)
Katariya, Payal Deepakbhai (PhD student)

Project: Private Foundations

5 Journal article

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2025
Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition
Jakobsen, M. K., Traynor, S., Nielsen, A. Y., Dahl, C., Staehr, M., Jakobsen, S. T., Madsen, M. S., Siersbaek, R., Terp, M. G., Jensen, J. B., Pedersen, C. B., Shrestha, A., Brewer, J. R., Duijf, P. H. G., Gammelgaard, O. L., Ditzel, H. J., Kirkin, A. F., Guldberg, P. & Gjerstorff, M. F., 23. Jan 2025, In: Journal of Experimental & Clinical Cancer Research. 44, 1, 15 p., 21.
Research output: Contribution to journal › Journal article › Research › peer-review

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Transcriptional regulation by MYC: an emerging new model
Jakobsen, S. T. & Siersbæk, R., 2025, In: Oncogene. 44, p. 1-7
Research output: Contribution to journal › Journal article › Research › peer-review
2024
MYC activates transcriptional enhancers to drive cancer progression
Siersbæk, R. & Jakobsen, S. T., Apr 2024, In: Nature Genetics. 56, 4, p. 567-568
Research output: Contribution to journal › Journal article › Communication
MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch
Jakobsen, S. T., Jensen, R. A. M., Madsen, M. S., Ravnsborg, T., Vaagenso, C. S., Siersbæk, M. S., Einarsson, H., Andersson, R., Jensen, O. N. & Siersbæk, R., 2024, In: Nature Genetics. 56, 4, p. 663–674
Research output: Contribution to journal › Journal article › Research › peer-review
2023
Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma
Ramesh, V., Gollavilli, P. N., Pinna, L., Siddiqui, M. A., Turtos, A. M., Napoli, F., Antonelli, Y., Leal-Egaña, A., Havelund, J. F., Jakobsen, S. T., Boiteux, E. L., Volante, M., Faergeman, N. J., Jensen, O. N., Siersbaek, R., Somyajit, K. & Ceppi, P., 7. Dec 2023, In: EMBO Molecular Medicine. 15, 12, e17836.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
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