Anaerobic bacteremia; Clinical presentation, treatment response and outcome.

Blood stream infection with anaerobic bacteria accounts for up to 10-15% of bacteremia cases. However, both laboratory diagnostics, clinical evaluation and treatment, have been challenging and anaerobic bacteremia remains associated with significant mortality.
1) In a regional population-based study, we will focus on Bacteroides species, the most common cause of anaerobic bacteremia, and examine the choice of antibiotic therapy in relation to clinical outcome, and mortality rate.
2) In a nationwide population-based study, we will investigate the epidemiology, and clinical manifestations of bacteremia with anaerobic bacteria. Furthermore, we aim to investigate comorbidities, including cancers related to anaerobic bacteremia.
3) In a prospective clinical study, we will examine patients with anaerobic bacteremia using camera capsule endoscopy for the presence of colorectal cancer (CRC), the most frequent and severe medical condition associated with anaerobic bacteremia.