Aage og Johanne Louis-Hansens Fond - Integrative machine learning analysis of single-cell and spatial transcriptomics during embryonic development

Project: Private Foundations

Project Details

Description

Denmark has the highest chronic inflammatory bowel disease (cIBD) incidence and
patient morbidity rate in the world. In my PhD, I will computationally model genomics data to identify, characterise cIBD immune dysregulation and pathogenesis at single-cell level.
Through the integrative analysis of multi-modal data, I will develop new models to identify key disease drivers and simulate in-silico perturbation at a higher resolution than in traditional studies. This work would be of significant interest to entire field of gastrointestinal biology and with potential clinical relevance.
StatusActive
Effective start/end date01/08/202031/07/2023