Troels Korshøj Bergmann

MD, phd, Consultant

  • J. B. Winsløws Vej 19, 2.

    5000 Odense C

    Denmark

20012019
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Research Output 2001 2019

2019

A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24

Mirza, M. R., Bergmann, T. K., Mau-Sørensen, M., Christensen, R. D., Åvall-Lundqvist, E., Birrer, M. J., Jørgensen, M., Roed, H., Malander, S., Nielsen, F., Lassen, U., Brøsen, K., Bjørge, L. & Mäenpää, J., Oct 2019, In : Cancer Chemotherapy and Pharmacology. 84, 4, p. 791-798

Research output: Contribution to journalJournal articleResearchpeer-review

Platinum
Angiogenesis Inhibitors
Germ-Line Mutation
Ovarian Neoplasms
Disease-Free Survival

Lægemiddelinteraktioner

Bergmann, T. K., Brøsen, K. & Christensen, H. R., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 992-1000

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

19 Downloads (Pure)

Progression-free survival in oncology: caveat emptor!

Bergmann, T. K., Christensen, M. M. H., Henriksen, D., Haastrup, M. B. & Damkier, P., 1. Mar 2019, In : Basic & Clinical Pharmacology & Toxicology. 124, 3, p. 240-244

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Oncology
Disease-Free Survival
Pharmaceutical Preparations
Health care
Neoplasms
2018
68 Downloads (Pure)

Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies

Tveden-Nyborg, P., Bergmann, T. K. & Lykkesfeldt, J., Sep 2018, In : Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Clinical Pharmacology
Clinical Studies

Clinical Pharmacokinetics of Paclitaxel Monotherapy: An Updated Literature Review

Stage, T. B., Bergmann, T. K. & Kroetz, D. L., 2018, In : Clinical Pharmacokinetics. 57, 1, p. 7-19

Research output: Contribution to journalReviewResearchpeer-review

Pharmacokinetics
Data Mining
Ovarian Neoplasms
Albumin-Bound Paclitaxel
cremophor
2017

ADHD-behandling og graviditet

Dideriksen, D., Hedegaard, U., Kuhlmann, I. B., Bergmann, T. K. & Christensen, M. M. H., 2017, In : Maanedsskrift for Almen Praksis. 95, 12, p. 1015-1019

Research output: Contribution to journalJournal articleCommunication

Anvendelse af p-piller og arvelig disposition for mammacancer

Hedegaard, U., Dideriksen, D. & Bergmann, T. K., 2017, In : Maanedsskrift for Almen Praksis. 95, 5, p. 439-443

Research output: Contribution to journalJournal articleCommunication

Clopidogrel paclitaxel drug-drug interaction: A pharmacoepidemiologic study

Agergaard, K., Mau-Sørensen, M., Stage, T. B., Jørgensen, T. L., Hassel, R. E., Dahl Steffensen, K., Pedersen, J. W., Milo, M. L. H., Poulsen, S. H., Pottegård, A., Hallas, J., Brøsen, K. & Bergmann, T. K., Sep 2017, In : Clinical Pharmacology and Therapeutics. 102, 3, p. 547–553

Research output: Contribution to journalJournal articleResearchpeer-review

clopidogrel
Drug Interactions
Pharmaceutical Preparations
Confidence Intervals
Glucuronides

Laktatacidose hos en yngre kvinde med status asthmaticus

Translated title of the contribution: Lactic acidosis in a 24-year-old woman with status asthmaticusRamazan-Yousif, L., Albertsen, S., Bergmann, T. K., Madsen, P. H. & Steen, N. P., 2017, In : Ugeskrift for Laeger. 2, p. 2-3

Research output: Contribution to journalJournal articleResearchpeer-review

Lactic Acidosis
Women's Rights
Lactic Acid
Intensive Care Units
Respiratory Insufficiency
109 Downloads (Pure)

The Pharmacogenetics of Tacrolimus in Corticosteroid-Sparse Pediatric and Adult Kidney Transplant Recipients

Juul Madsen, M., Bergmann, T. K., Brøsen, K. & Thiesson, H. C., 2017, In : Drugs in R&D. 17, 2, p. 279–286

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cytochrome P-450 CYP3A
Pharmacogenetics
Tacrolimus
Adrenal Cortex Hormones
Pediatrics
2016

A Cancer That Went Up in Smoke: Pulmonary Reaction to e-Cigarettes Imitating Metastatic Cancer

Ring Madsen, L., Vinther Krarup, N. H., Bergmann, T. K., Bærentzen, S., Neghabat, S., Duval, L. & Knudsen, S. T., Mar 2016, In : Chest. 149, 3, p. e65-67

Research output: Contribution to journalJournal articleResearchpeer-review

Smoke
Lung
Neoplasms
Liver
Giant Cells

Akut psykose ved ophør af langvarig tramadolbehandling − overser vi tramadols serotonerge virkning?

Østergaard Rathe, J., Dideriksen, D., Carstens, J. & Bergmann, T. K., 2016, In : Maanedsskrift for Almen Praksis. 2016, 8, p. 637-641

Research output: Contribution to journalJournal articleCommunication

Fluconazol og amning

Pedersen, A. J. T., Hessellund, A., Bergmann, T. K. & Damkier, P., 2016, In : Maanedsskrift for Almen Praksis. 2016, 12, p. 1 4 p., 11664.

Research output: Contribution to journalJournal articleCommunication

LBA50 - Influence of concomitant clopidogrel consumption on development of paclitaxel-associated toxicity: A pharmacoepidemiological study

K, A., Mau-Sørensen, M., Stage, T. B., Dahl Steffensen, K., Hallas, J., Brøsen, K. & Bergmann, T. K., 8. Oct 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Open Access

Natlige lægkramper og kininbehandling

Albertsen, S., Østergaard Rathe, J. & Bergmann, T. K., Feb 2016, In : Maanedsskrift for Almen Praksis. 97, p. 169 4 p.

Research output: Contribution to journalJournal articleCommunication

101 Downloads (Pure)

Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants

Lyauk, Y. K., Stage, C., Bergmann, T. K., Ferrero-Milliani, L., Bjerre, D., Thomsen, R., Dalhoff, K. P., Rasmussen, H. B. & Jürgens, G., 2016, In : Clinical and Translational Science (Print). 9, 6, p. 337-345

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Carboxylesterase
Methylphenidate
Pharmacokinetics
Population
Plasmas

Simvastatin og graviditet

Hedegaard, U., Kuhlmann, I. B., Østergaard Rathe, J., Bergmann, T. K. & Damkier, P., 2016, In : Maanedsskrift for Almen Praksis. 2016, 11, p. 836-840

Research output: Contribution to journalJournal articleCommunication

2015

Docetaxel-induced neuropathy: A pharmacogenetic case-control study of 150 women with early-stage breast cancer

Eckhoff, L., Feddersen, S., Knoop, A., Ewertz, M. & Bergmann, T. K., 2015, In : Acta Oncologica. 54, 4, p. 530-7

Research output: Contribution to journalJournal articleResearchpeer-review

docetaxel
Pharmacogenetics
Case-Control Studies
Peripheral Nervous System Diseases

Exploratory Study of Total and Free Prednisolone Plasma Exposure and Cushingoid Appearance, Quality of Life and Biochemical Toxicity in Adult Male Kidney Transplant Recipients

Bergmann, T. K., Isbel, N. M., Ostini, R., Barraclough, K. A., Campbell, S. B., McWhinney, B. C., Inder, W. J., Russell, A. & Staatz, C. E., 2015, In : Clinical Drug Investigation. 35, 11, p. 743-750

Research output: Contribution to journalJournal articleResearchpeer-review

Quality of Life
Kidney
Glucocorticoids
Lipids
Dyslipidemias

Neurotoxicity and low paclitaxel clearance associated with concomitant clopidogrel therapy in a 60 year old Caucasian woman with ovarian carcinoma

Bergmann, T. K., Filppula, A. M., Launiainen, T., Nielsen, F., Backman, J. & Brosen, K., 7. Oct 2015, In : British Journal of Clinical Pharmacology. 81, 2, p. 313-315

Research output: Contribution to journalJournal articleResearchpeer-review

clopidogrel
Glucuronides

Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel: Letter

Apellániz-Ruiz, M., Sánchez-Barroso, L., Gutiérrez-Gutiérrez, G., Sereno, M., García-Donás, J., Åvall-Lundqvist, E., Gréen, H., Brøsen, K., Bergmann, T. K. & Rodríguez-Antona, C., 1. Jul 2015, In : Clinical Cancer Research. 21, 13, p. 3092-3

Research output: Contribution to journalComment/debateResearchpeer-review

Role of cytochrome P450 2C8*3 (CYP2C8*3) in paclitaxel metabolism and paclitaxel-induced neurotoxicity

Lee, M-Y., Apellániz-Ruiz, M., Johansson, I., Vikingsson, S., Bergmann, T. K., Brøsen, K., Green, H., Rodríguez-Antona, C. & Ingelman-Sundberg, M., Jun 2015, In : Pharmacogenomics. 16, 9, p. 929-37

Research output: Contribution to journalJournal articleResearchpeer-review

Cytochrome P-450 Enzyme System
rosiglitazone
Alleles
HEK293 Cells

Tacrolimus pharmacokinetics after kidney transplantation: Influence of changes in haematocrit and steroid dose

Staatz, C. E., Størset, E., Bergmann, T. K., Hennig, S. & Holford, N., 2. Aug 2015, In : British Journal of Clinical Pharmacology. 80, 6, p. 1475-1476

Research output: Contribution to journalComment/debateResearchpeer-review

2014

Comparison of the influence of cyclosporine and tacrolimus on the pharmacokinetics of prednisolone in adult male kidney transplant recipients

Bergmann, T. K., Isbel, N. M., Barraclough, K. A., Campbell, S. B., McWhinney, B. C. & Staatz, C. E., Mar 2014, In : Clinical Drug Investigation. 34, 3, p. 183-8

Research output: Contribution to journalJournal articleResearchpeer-review

Tacrolimus
Cyclosporine
Pharmacokinetics
Kidney
Area Under Curve

Improved prediction of tacrolimus concentrations early after kidney transplantation using theory-based pharmacokinetic modelling

Størset, E., Holford, N., Hennig, S., Bergmann, T. K., Bergan, S., Bremer, S., Åsberg, A., Midtvedt, K. & Staatz, C. E., Sep 2014, In : British Journal of Clinical Pharmacology. 78, 3, p. 509-23

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Tacrolimus
Kidney Transplantation
Pharmacokinetics
Hematocrit
Fats

Population pharmacokinetics of tacrolimus in adult kidney transplant patients: impact of CYP3A5 genotype on starting dose

Bergmann, T. K., Hennig, S., Barraclough, K. A., Isbel, N. M. & Staatz, C. E., Feb 2014, In : Therapeutic Drug Monitoring. 36, 1, p. 62-70

Research output: Contribution to journalJournal articleResearchpeer-review

Cytochrome P-450 CYP3A
Tacrolimus
Pharmacokinetics
Kidney
Population

The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis

Therkildsen, C., Bergmann, T. K., Henrichsen-Schnack, T., Ladelund, S. & Nilbert, M., Jul 2014, In : Acta Oncologica. 53, 7, p. 852-64

Research output: Contribution to journalReviewResearchpeer-review

Meta-Analysis
Colorectal Neoplasms
Mutation
Disease-Free Survival
Odds Ratio
2013

GWAS-based association between RWDD3 and TECTA variants and paclitaxel induced neuropathy could not be confirmed in Scandinavian ovarian cancer patients

Bergmann, T. K., Vach, W., Feddersen, S., Eckhoff, L., Gréen, H., Herrstedt, J. & Brosen, K., 9. Aug 2013, In : Acta Oncologica. 52, 4, p. 871-873

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Clinical pharmacokinetics and pharmacodynamics of prednisolone and prednisone in solid organ transplantation

Bergmann, T. K., Barraclough, K. A., Lee, K. J. & Staatz, C. E., 2012, In : Clinical Pharmacokinetics. 51, 11, p. 711-741

Research output: Contribution to journalJournal articleResearchpeer-review

Prednisone
Pharmacokinetics
Adrenal Cortex Hormones
Immunosuppressive Agents
Pharmaceutical Preparations

Impact of ABCB1 Variants on Neutrophil Depression: A Pharmacogenomic Study of Paclitaxel in 92 Women with Ovarian Cancer

Bergmann, T. K., Andersen, C. B., Gréen, H., Mirza, M. R., Skougaard, K., Wihl, J., Keldsen, N., Damkier, P., Peterson, C., Vach, W. & Brøsen, K., 2012, In : Basic & Clinical Pharmacology & Toxicology. 110, 2, p. 199-204

Research output: Contribution to journalJournal articleResearchpeer-review

Paclitaxel
Ovarian Neoplasms
Neutrophils
Toxicity
Chemotherapy

NR1I2 polymorphisms are related to tacrolimus dose-adjusted exposure and BK viremia in adult kidney transplantation

Barraclough, K. A., Isbel, N. M., Lee, K. J., Bergmann, T. K., Johnson, D. W., McWhinney, B. C., Ungerer, J. P. J., Campbell, S. B., Leary, D. R., Bialasiewicz, S., Rockett, R. J. & Staatz, C. E., 2012, In : Transplantation. 94, 10, p. 1025-1032

Research output: Contribution to journalJournal articleResearchpeer-review

Tacrolimus
Kidney Transplantation
Alleles
Mycophenolic Acid
Immunosuppressive Agents

Pharmacokinetics of Lumefantrine in Adults Co-Infected with Malaria and HIV-1: with and without Efavirenz-Based Antiretroviral Therapy

Musoke, D., Bergmann, T. K., Ntale, M., Sodemann, M. & Ogwal-Okeng, J., 2012, In : International Journal of Tropical Medicine. 7, 5, p. 187-192

Research output: Contribution to journalJournal articleResearchpeer-review

2011
548 Downloads (Pure)

Impact of CYP2C8*3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer

Bergmann, T. K., Brasch-Andersen, C., Gréen, H., Mirza, M., Pedersen, R. S., Nielsen, F., Skougaard, K., Wihl, J., Keldsen, N., Damkier, P., Friberg, L. E., Peterson, C., Vach, W., Karlsson, M. O. & Brøsen, K., 2011, In : Pharmacogenomics Journal. 11, 2, p. 113-120

Research output: Contribution to journalJournal articleResearchpeer-review

File
Ovarian Neoplasms
Pharmacokinetics
Population
Pharmacogenetics
Carboplatin

Retrospective study of the impact of pharmacogenetic variants on paclitaxel toxicity and survival in patients with ovarian cancer

Bergmann, T. K., Gréen, H., Andersen, C. B., Mirza, M. R., Herrstedt, J., Hølund, B., du Bois, A., Damkier, P., Vach, W., Brøsen, K. & Peterson, C., 2011, In : European Journal of Clinical Pharmacology. 67, 7, p. 693-700

Research output: Contribution to journalJournal articleResearchpeer-review

Ovarian Neoplasms
Retrospective Studies
Cytochrome P-450 CYP3A
P-Glycoprotein
Neutropenia

Skræddersyet kemoterapi

Bergmann, T. K. & Qvortrup, C., 2011, In : BestPractice. 1, p. 24-27

Research output: Contribution to journalJournal articleCommunication

2010

Impact of ABCB1 variants on neutrophil depression: a prospective study

Bergmann, T. K., Andersen, C. B., Gréen, H., Mirza, M. R., Skougaard, K., Wihl, J., Keldsen, N., Damkier, P., Peterson, C., Vach, W. & Brøsen, K., 2010.

Research output: Contribution to conference without publisher/journalPosterResearch

Neutrophils
Prospective Studies
Ovarian Neoplasms
Carboplatin
Neutropenia

Läkemedelsinteraktioner inom medicinsk onkologi och hematologi

Bergmann, T. K. & Gullbo, J. (ed.), 2010, Uppsala, Sverige. 87 p.

Research output: Book/anthology/thesis/reportBookCommunication

Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations

Pedersen, R. S., Brasch Andersen, C., Sim, S. C., Bergmann, T. K., Halling, J., Petersen, M. S., Weihe, P., Edvardsen, H., Kristensen, V. N., Brøsen, K. & Ingelman-Sundberg, M., 2010, In : European Journal of Clinical Pharmacology. 66, 12, p. 1199-1205

Research output: Contribution to journalJournal articleResearchpeer-review

Linkage Disequilibrium
Haplotypes
Alleles
Population
Cytochrome P-450 CYP2C9
2009
89 Downloads (Pure)

Impact of CYP2C8*3 on paclitaxel clearance in ovarian cancer patients

Bergmann, T. K., Vach, W., Gréen, H., Karlsson, M., Friberg, L., Nielsen, F., Pedersen, R. S., Mirza, M. R., Andersen, C. B. & Brøsen, K., 2009.

Research output: Contribution to conference without publisher/journalPosterResearch

Open Access
File
2008

Lægemiddelinteraktioner i Medicinsk Onkologi og Hæmatologi

Bergmann, T. K., 2008, 1 ed. Syddansk Universitet. Klinisk Farmakologi. 96 p.

Research output: Book/anthology/thesis/reportBookCommunication

No evidence for taxane/platinum pharmacogenetic markers: just lack of power?

Vach, W., Bergmann, T. K. & Brøsen, K., 10. Apr 2008, In : Journal of Clinical Oncology. 26, 11, p. 1903-4 2 p.

Research output: Contribution to journalLetterResearch

Paclitaxels farmakogenomik hos patienter med kræft i æggestokken

Bergmann, T. K., Mirza, M. R., Andersen, C. B., Hølund, B., Vach, W., Damkier, P. & Brøsen, K., 2008.

Research output: Contribution to conference without publisher/journalPosterResearch

2001

Duplicatio of CYP2D6 predicts high clearance of desipramine but high clearance does not predict duplication of CYP2D6

Bergmann, T. K., Bathum, L. & Brøsen, K., 2001, In : European Journal of Clinical Pharmacology. 57, 2, p. 123-127 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cytochrome P-450 CYP2D6
Desipramine
Volunteers
Gene Duplication
Hydroxylation

Multiple hepatic abscesses due to Yersinia enterocolitica infection secondary to primary haemochromatosis

Bergmann, T. K., Vinding, K. & Hey, H., 1. Aug 2001, In : Scandinavian Journal of Gastroenterology. 36, 8, p. 891-5 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Yersinia enterocolitica
Hemochromatosis
Nuclear Family
Diabetes Mellitus
Iron