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Personal profile

Research areas

The research in my group focuses on understanding transcriptional networks regulating cellular differentiation and function in mammalian cells. We are specifically interested in the molecular cross-talk between transcriptional regulation and metabolism in adipocytes and pancreatic beta-cells, and in the transcriptional network regulating adipocyte differentiation.

For further information see:

http://www.sdu.dk/mandrupgroup  

Fingerprint Dive into the research topics where Susanne Mandrup is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Adipocytes Medicine & Life Sciences
Diazepam Binding Inhibitor Medicine & Life Sciences
Adipogenesis Medicine & Life Sciences
PPAR gamma Medicine & Life Sciences
Peroxisome Proliferator-Activated Receptors Chemical Compounds
Genes Chemical Compounds
Transcriptional Activation Medicine & Life Sciences
PPAR alpha Medicine & Life Sciences

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Research Output 1992 2019

Adipogenesis
Stem Cell Factor
Osteogenesis
Color
44 Downloads (Pure)

Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism

Pearson, S., Loft, A., Rahbhandari, P., Simcox, J., Lee, S., Tontonoz, P., Mandrup, S. & Villanueva, C. J., 1. Jul 2019, In : Genes & Development. 33, 13-14, p. 747-762 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Transducin
Mitochondrial Genes
White Adipose Tissue
Chromatin Immunoprecipitation
Oxidative Phosphorylation

Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

Rauch, A., Haakonsson, A. K., Madsen, J. G. S., Larsen, M., Forss, I., Madsen, M. R., Van Hauwaert, E. L., Wiwie, C., Jespersen, N. Z., Tencerova, M., Nielsen, R., Larsen, B. D., Röttger, R., Baumbach, J., Scheele, C., Kassem, M. & Mandrup, S., Apr 2019, In : Nature Genetics. 51, 4, p. 716-727

Research output: Contribution to journalJournal articleResearchpeer-review

Adipogenesis
Stem Cell Factor
Mesenchymal Stromal Cells
Osteogenesis
Chromatin Assembly and Disassembly
44 Downloads (Pure)

Time-Resolved Systems Medicine Reveals Viral Infection-Modulating Host Targets

Wiwie, C., Kuznetsova, I., Mostafa, A., Rauch, A., Haakonsson, A., Barrio-Hernandez, I., Blagoev, B., Mandrup, S., Schmidt, H. H. H. W., Pleschka, S., Röttger, R. & Baumbach, J., 2019, In : Systems medicine (New Rochelle, N.Y.). 2, 1, 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Virus Diseases
Influenza A virus
Pharmaceutical Preparations
Orthomyxoviridae
Proteins
163 Downloads (Pure)

Transcriptional regulation of Hepatic Stellate Cell activation in NASH

Marcher, A-B., Bendixen, S. M., Terkelsen, M. K., Hohmann, S. S., Hansen, M. H., Larsen, B. D., Mandrup, S., Dimke, H., Detlefsen, S. & Ravnskjaer, K., 20. Feb 2019, In : Scientific Reports. 9, 1, 55 p., 2324.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hepatic Stellate Cells
Fatty Liver
Liver
Liver Diseases
Extracellular Matrix Proteins

Activities 2003 2019

ATLAS Annual meeting 2019

Susanne Mandrup (Organizer)
2. Jul 2019

Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

ATLAS Symposium 2019 - Tissue Plasticity of Obesity

Susanne Mandrup (Organizer), Lars Grøntved (Chairman), Kim Ravnskjær (Chairman), Blagoy Blagoev (Chairman), Jesper Grud Skat Madsen (Chairman), Aleksander Krag (Chairman), Søren Kragh Moestrup (Chairman), Jonas Heilskov Graversen (Chairman)
30. Jun 20191. Jul 2019

Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

Speaker at CPH BAT 2019

Susanne Mandrup (Lecturer)
4. Jun 2019

Activity: Talks and presentationsConference presentations

ADIPOSIGN Opening Sympoisum

Susanne Mandrup (Organizer), Marianne Holmer (Panel member), Jakob Møller-Jensen (Panel member), Jan-Wilhelm Kornfeld (Panel member), Zachary Gerhart-Hines (Panel member), M. Madan Babu (Panel member), Matthias Blüher (Panel member), Ruth J F Loos (Panel member), Martin Klingenspor (Panel member), Christian Wolfrum (Panel member)
27. May 2019

Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

Cold Spring Harbor Laboratory meeting: "Mechanisms of Metabolic Signaling"

Susanne Mandrup (Organizer)
14. May 201918. May 2019

Activity: Attending an eventConference organisation or participation

Projects 2005 2024

Press / Media

FRA HOFFET

Susanne Mandrup

09/11/2019

1 Media contribution

Press/Media: Press / Media

ORDENER

Susanne Mandrup

06/11/2019

1 Media contribution

Press/Media: Press / Media

MEDALJER

Susanne Mandrup

05/11/2019

1 Media contribution

Press/Media: Press / Media

Dronningen har tildelt 18 medaljer

Susanne Mandrup

04/11/2019

1 Media contribution

Press/Media: Press / Media

Dronningen har tildelt 18 medaljer

Susanne Mandrup

04/11/2019

1 Media contribution

Press/Media: Press / Media