• Campusvej 55

    5230 Odense M

    Denmark

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Personal profile

Curriculum

University Address:

Nucleic Acid Center
Department of Physics and Chemistry
University of Southern Denmark, Odense
Campusvej 55
DK-5230 Odense M, Denmark
phone +45 6550 2510
Fax +45 6615 8780

E-mail: snv@ifk.sdu.dk

Education:

  • Diplom (MSc) in Chemistry at the University of Leipzig (1997)
  •  Dr. rer. nat (PhD) at the University of Leipzig, Supervision Prof. Peter Welzel "Moenomycin antibiotics" (2001)


Professional Experience:

  •   Associate Professor in Nanobioscience (University of Southern Denmark, 2006 - )
  •   Assistant Professor in Bioorganic Chemistry (2003-2006, University of Southern Denmark)
  •   Postdoctoral Fellow (2002, Nucleic Acid Center, awarded by the German Research Foundation - DFG)
  •   Postdoctoral Fellow at the Nucleic Acid Center (2001, University of Southern Denmark)
  •   Researcher (1997-1998, Aventis AG, France, Paris)

Research areas

Current Research:

  • Medidinal chemistry of nucleic acids with focus on targeted delivery of modified oligonucleotides
  • Microwave assisted and automated synthesis of peptides
  • Controlled assembly and fusion of biomembranes (liposomes)
  • Automated synthesis of DNA-conjugates and synthesis of non nucleosidic building blocks
  • Synthesis and characterisation of soft nanoparticles (liposomes)
  • Synthesis of radioligands with focus on PET-Imaging
  • Synthesis of bioconjugates for theranostic applications

Research areas

  • Chemistry
  • organic chemistry
  • bioorganic chemistry
  • peptides
  • Nucleic acids
  • DNA
  • RNA
  • oligonucleotides
  • Supramolecular chemistry
  • macrocycles
  • assembly
  • fusion
  • Medical chemistry
  • targeted delivery
  • Synthetic biology
  • membrane fusion
  • biophysics
  • Nanotechnology and nanoscience
  • nanoparticles
  • Nanomedicine

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Research Output

DNA-Mediated Liposome Fusion Observed by Fluorescence Spectrometry

Löffler, P. M. G., Ries, O. & Vogel, S., 2020, Nucleic Acid Detection and Structural Investigations: Methods and Protocols. Astakhova, K. & Bukhari, S. A. (eds.). Humana Press, Vol. 2063. p. 101-118 18 p. (Methods in Molecular Biology, Vol. 2063).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  • Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo

    Arias-Alpizar, G., Kong, L., Vlieg, R. C., Rabe, A., Papadopoulou, P., Meijer, M. S., Bonnet, S., Vogel, S., van Noort, J., Kros, A. & Campbell, F., 2020, In : Nature Communications. 11, 3638.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
  • 29 Downloads (Pure)

    Lipid-Modified Peptide Nucleic Acids: Synthesis and Application to Programmable Liposome Fusion

    Löffler, P. M. G., Rabe, A. & Vogel, S., 2020, Peptide Nucleic Acids. Nielsen, P. E. (ed.). Vol. 2105. p. 75-96 22 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  • A large size-selective DNA nanopore with sensing applications

    Thomsen, R. P., Malle, M. G., Okholm, A. H., Krishnan, S., Nielsen, S. S-R., Sørensen, R. S., Ries, O., Vogel, S., Simmel, F., Hatzakis, N. & Kjems, J., 11. Dec 2019, In : Nature Communications. 10, 5655.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
  • 64 Downloads (Pure)

    Lipidated Polyaza Crown Ethers as Membrane Anchors for DNA-Controlled Content Mixing between Liposomes

    Löffler, P. M. G., Hansen, A. H., Ries, O., Jakobsen, U., Rabe, A., Sørensen, K. T., Glud, K. & Vogel, S., 25. Sep 2019, In : Scientific Reports. 9, 11 p., 13856.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
  • 148 Downloads (Pure)

    Activities

    Lipidated-Oligonucleotides with applications in programmed fusion of biomembranes and delivery of DNA

    Stefan Vogel (Guest lecturer)

    7. Feb 2020

    Activity: Talks and presentationsGuest lectures, external teaching and course activities at other universities

    DNA-Programmed Fusion of Lipid-Nanoparticle Chemical Reactors

    Stefan Vogel (Guest lecturer)

    9. Jul 2019

    Activity: Talks and presentationsConference presentations

    2019 Annual meeting of The Danish Chemical Society

    Stefan Vogel (Organizer)

    30. Jun 2019

    Activity: Attending an eventConference organisation or participation

    File

    Towards Programmable Chemistry in Water

    Stefan Vogel (Guest lecturer)

    16. May 2019

    Activity: Talks and presentationsConference presentations

    Meeting of the Nordic Chemical Societies

    Stefan Vogel (Organizer)

    3. May 20194. May 2019

    Activity: Attending an eventConference organisation or participation

    Projects

    Prizes

    Multi-angle light scattering detector for existing Asymmetrical Flow Field-Flow Fractionation (AF4) instrument

    Brandl, Martin (Recipient), Kinoshita, Koji (Recipient), Wu, Changzhu (Recipient), Kuntsche, Judith (Recipient), Stein, Paul C. (Recipient), Vogel, Stefan (Recipient), Bauer-Brandl, Annette (Recipient), Daniel Bar-Shalom (Recipient), Jette Jacobsen (Recipient) & Camilla Foged (Recipient), 21. Nov 2018

    Prize: Prizes, scholarships, distinctions

    Teaching & Supervision

    KE805 Supramolecular and Nanochemistry

    Stefan Vogel

    01/09/200731/01/2018

    Course: Teaching

    FA506 Medicinal Chemistry

    Stefan Vogel

    01/09/2018 → …

    Course: Teaching

    KE806 Advanced Synthesis

    Stefan Vogel

    01/09/2007 → …

    Course: Teaching