Rikke Leth-Larsen

MSc, Ph.D, LAICS

  • J. B. Winsløws Vej 19, 3

    5000 Odense C

    Denmark

19962019
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Personal profile

Research areas

My current research is aimed at organization and management. My previous research is related to breast cancer focusing on the metastatic process and cancer stem cells. Using, among other things, quantitative proteomic analysis we identify proteins and their post-translational modifications, which are expressed differently on metastatic compared to non-metastatic breast cancer cells. These proteins and their modifications are potentially involved in breast cancer cells' ability to metastasize and may be a target for therapeutic treatment of patients.

Research areas

  • Health and Illness

Fingerprint Dive into the research topics where Rikke Leth-Larsen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Profiles
Pulmonary Surfactant-Associated Protein D Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cells Chemical Compounds
Neoplasms Medicine & Life Sciences
Pulmonary Surfactant-Associated Proteins Medicine & Life Sciences
Cell membranes Chemical Compounds
Tumors Chemical Compounds
Gadus morhua Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1996 2019

51 Downloads (Pure)

CYPOR is a novel and independent prognostic biomarker of recurrence-free survival in triple-negative breast cancer patients

Pedersen, M. H., Hood, B. L., Ehmsen, S., Beck, H. C., Conrads, T. P., Bak, M., Ditzel, H. J. & Leth-Larsen, R., 1. Feb 2019, In : International Journal of Cancer. 144, 3, p. 631-640

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
NADPH-Ferrihemoprotein Reductase
Paraffin
Formaldehyde
Lymph Nodes
Regression Analysis
75 Downloads (Pure)

Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome

Ehmsen, S., Pedersen, M. H., Wang, G., Terp, M. G., Arslanagic, A., Hood, B. L., Conrads, T. P., Leth-Larsen, R. & Ditzel, H. J., 25. Jun 2019, In : Cell Reports. 27, 13, p. 3927-3938.e6

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Biosynthesis
Stem cells
Cholesterol
Tumors
Hydroxymethylglutaryl-CoA Reductase Inhibitors

Proteomic comparison of clinical breast cancer samples, corresponding patient derived xenografts (PDX) and mammospheres reveal increased cholesterol biosynthesis as a key feature of cancer stem cells

Ehmsen, S., Pedersen, M. H., Arslanagic, A., Terp, M. G., Leth-Larsen, R., Ditzel, H., Hood, B. L. & Conrads, T. P., 4. May 2018.

Research output: Contribution to conference without publisher/journalPosterCommunication

Research integrity among PhD students within clinical research at the University of Southern Denmark

Bredahl, L., Kyvik, K. O., Leth-Larsen, R. & Eriksen, M. B., 1. Apr 2018, In : Danish Medical Journal. 65, 4, 5 p., A5469.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Denmark
Scientific Misconduct
Research
Plagiarism
Publications

Downregulation of antigen presentation-associated pathway proteins is linked to poor outcome in triple-negative breast cancer patient tumors

Pedersen, M. H., Hood, B. L., Beck, H. C., Conrads, T. P., Ditzel, H. & Leth-Larsen, R., 16. Mar 2017, In : OncoImmunology. 6, 5, 14 p., e1305531.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Antigen Presentation
Down-Regulation
Neoplasms
Proteins
Tumor-Infiltrating Lymphocytes

Activities 2006 2018

Forskningens dag 2018: Region Sjælland

Rikke Leth-Larsen (Chairman)
20. Sep 2018

Activity: Attending an eventConference organisation or participation

Kunsten at kommunikere 2018

Rikke Leth-Larsen (Participant)
7. Jun 2018

Activity: Attending an eventConference organisation or participation

Åben Forskerdag

Rikke Leth-Larsen (Organizer)
23. Apr 2018

Activity: Attending an eventConference organisation or participation

Frontiers in Patient Safety

Rikke Leth-Larsen (Chairman), Erik Hollnagel (Organizer), Kathleen Sutcliffe (Organizer), Bjarne Dahler-Eriksen (Organizer), Christian von Plessen (Organizer)
20. Apr 2018

Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

Åben forskerdag

Rikke Leth-Larsen (Organizer)
26. Apr 2017

Activity: Attending an eventConference organisation or participation

Press / Media

Clinical Professor in Cardiology (combined position)

Rikke Leth-Larsen

23/02/2019

1 Media contribution

Press/Media: Press / Media

Clinical professor in neurology (combined position)

Rikke Leth-Larsen

23/11/2018

1 Media contribution

Press/Media: Press / Media

Peroral kolangioskopi

Rikke Leth-Larsen

02/04/2018

1 Media contribution

Press/Media: Press / Media