Rikke Leth-Larsen

MSc, Ph.D, LAICS

Visiting Researcher, Ditzel group
Head of Department, KI, BRIDGE, Brain Research - Inter-Disciplinary Guided Excellence
Head of Department, IRS - Department Secretary

https://orcid.org/0000-0002-1612-4089

Phone65503913, 30827801
Emailrllarsen@health.sdu.dk

J. B. Winsløws Vej 19, 3
5000 Odense C
Denmark

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Personal profile

Research areas

My current research is aimed at organization and management. My previous research is related to breast cancer focusing on the metastatic process and cancer stem cells. Using, among other things, quantitative proteomic analysis we identify proteins and their post-translational modifications, which are expressed differently on metastatic compared to non-metastatic breast cancer cells. These proteins and their modifications are potentially involved in breast cancer cells' ability to metastasize and may be a target for therapeutic treatment of patients.

Research areas

Health and Illness

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34 Journal article
21 Poster

MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit
Løkkegaard, S., Elias, D., Alves, C. L., Bennetzen, M. V., Lænkholm, A. V., Bak, M., Gjerstorff, M. F., Johansen, L. E., Vever, H., Bjerre, C., Kirkegaard, T., Nordenskjöld, B., Fornander, T., Stål, O., Lindström, L. S., Esserman, L. J., Lykkesfeldt, A. E., Andersen, J. S., Leth-Larsen, R. & Ditzel, H. J., Jan 2021, In: npj Breast Cancer. 7, 15 p., 2.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File
28 Downloads (Pure)
CYPOR is a novel and independent prognostic biomarker of recurrence-free survival in triple-negative breast cancer patients
Pedersen, M. H., Hood, B. L., Ehmsen, S., Beck, H. C., Conrads, T. P., Bak, M., Ditzel, H. J. & Leth-Larsen, R., 1. Feb 2019, In: International Journal of Cancer. 144, 3, p. 631-640
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File
168 Downloads (Pure)
Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome
Ehmsen, S., Pedersen, M. H., Wang, G., Terp, M. G., Arslanagic, A., Hood, B. L., Conrads, T. P., Leth-Larsen, R. & Ditzel, H. J., 25. Jun 2019, In: Cell Reports. 27, 13, p. 3927-3938.e6
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File
157 Downloads (Pure)
Proteomic comparison of clinical breast cancer samples, corresponding patient derived xenografts (PDX) and mammospheres reveal increased cholesterol biosynthesis as a key feature of cancer stem cells
Ehmsen, S., Pedersen, M. H., Arslanagic, A., Terp, M. G., Leth-Larsen, R., Ditzel, H., Hood, B. L. & Conrads, T. P., 4. May 2018.
Research output: Contribution to conference without publisher/journal › Poster › Communication
Research integrity among PhD students within clinical research at the University of Southern Denmark
Bredahl, L., Kyvik, K. O., Leth-Larsen, R. & Eriksen, M. B., 1. Apr 2018, In: Danish Medical Journal. 65, 4, 5 p., A5469.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File
103 Downloads (Pure)

20 Conference organisation or participation
12 Organisation or participation in workshops, courses or seminars
10 Membership of review committee
6 Talks and presentations in private or public companies
More

Forskningens dag 2018: Region Sjælland
Rikke Leth-Larsen (Chairman)
20. Sep 2018
Activity: Attending an event › Conference organisation or participation
Kunsten at kommunikere 2018
Rikke Leth-Larsen (Participant)
7. Jun 2018
Activity: Attending an event › Conference organisation or participation
Åben Forskerdag
Rikke Leth-Larsen (Organizer)
23. Apr 2018
Activity: Attending an event › Conference organisation or participation
Frontiers in Patient Safety
Rikke Leth-Larsen (Chairman), Erik Hollnagel (Organizer), Kathleen Sutcliffe (Organizer), Bjarne Dahler-Eriksen (Organizer) & Christian von Plessen (Organizer)
20. Apr 2018
Activity: Attending an event › Organisation or participation in workshops, courses or seminars
Åben forskerdag
Rikke Leth-Larsen (Organizer)
26. Apr 2017
Activity: Attending an event › Conference organisation or participation

Clinical Professor in Cardiology (combined position)
Rikke Leth-Larsen
23/02/2019
1 Media contribution
Press/Media: Press / Media
RE-ADVERTISEMENT Clinical professor in neurology (combined position)
Rikke Leth-Larsen
23/02/2019
1 Media contribution
Press/Media: Press / Media
Associate Professor in Psychological Rehabilitation within Rheumatology
Rikke Leth-Larsen
23/01/2019
1 Media contribution
Press/Media: Press / Media
Clinical professor in neurology (combined position)
Rikke Leth-Larsen
23/11/2018
1 Media contribution
Press/Media: Press / Media
Peroral kolangioskopi
Rikke Leth-Larsen
02/04/2018
1 Media contribution
Press/Media: Press / Media