Research output per year
Research output per year
- 38 results
Search results
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2024
Dietary intake of a MFGM/EV-rich concentrate promotes accretion of very long odd-chain sphingolipids and increases lipid metabolic turnover at the whole-body level
Sprenger, R. R., Bilgin, M., Ostenfeld, M. S., Bjørnshave, A., Rasmussen, J. T. & Ejsing, C. S., Aug 2024, In: Food Research International. 190, 15 p., 114601.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Downloads (Pure) -
Lipidomic Characterization of Whey Concentrates Rich in Milk Fat Globule Membranes and Extracellular Vesicles
Sprenger, R. R., Ostenfeld, M. S., Bjørnshave, A., Rasmussen, J. T. & Ejsing, C. S., 2024, In: Biomolecules. 14, 1, 13 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile23 Downloads (Pure) -
Lipotype acquisition during neural development is not recapitulated in stem cell-derived neurons
Gopalan, A. B., van Uden, L., Sprenger, R. R., Fernandez-Novel Marx, N., Bogetofte, H., Neveu, P. A., Meyer, M., Noh, K.-M., Diz-Muñoz, A. & Ejsing, C. S., 28. Feb 2024, In: Life Science Alliance. 7, 5, 13 p., e202402622.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile15 Downloads (Pure) -
2022
Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets
Henriksen, N. L., Asmussen, K. S., Pan, X., Jiang, P. P., Mori, Y., Christiansen, L. I., Sprenger, R. R., Ejsing, C. S., Pankratova, S. & Thymann, T., 28. Feb 2022, In: Scientific Reports. 12, 10 p., 3303.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile49 Downloads (Pure) -
Cholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets
Henriksen, N. L., Hansen, S. H., Lycas, M. D., Pan, X., Eriksen, T., Johansen, L. S., Sprenger, R. R., Ejsing, C. S., Burrin, D. G., Skovgaard, K., Christensen, V. B., Thymann, T. & Pankratova, S., Jul 2022, In: Physiological Reports. 10, 13, e15368.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile62 Downloads (Pure) -
DDA-imaging with structural identification of lipid molecules on an Orbitrap Velos Pro mass spectrometer
Khalil, S. M., Sprenger, R. R., Hermansson, M. & Ejsing, C. S., Sept 2022, In: Journal of Mass Spectrometry. 57, 9, e4882.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile84 Downloads (Pure) -
Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids
Renne, M. F., Bao, X., Hokken, M. W. J., Bierhuizen, A. S., Hermansson, M., Sprenger, R. R., Ewing, T. A., Ma, X., Cox, R. C., Brouwers, J. F., De Smet, C. H., Ejsing, C. S. & de Kroon, A. I. P. M., 17. Jan 2022, In: The EMBO Journal. 41, 2, 16 p., e106837.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile46 Downloads (Pure) -
Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death
Schmidt, S., Gallego, S. F., Zelnik, I. D., Kovalchuk, S., Albæk, N., Sprenger, R. R., Øverup, C., Pewzner-Jung, Y., Futerman, A. H., Lindholm, M. W., Jensen, O. N. & Ejsing, C. S., 6. Apr 2022, In: Molecular Therapy. 30, 4, p. 1661-1674Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile62 Downloads (Pure) -
2021
Dairy-derived emulsifiers in infant formula show marginal effects on the plasma lipid profile and brain structure in preterm piglets relative to soy lecithin
Henriksen, N. L., Aasmul-Olsen, K., Venkatasubramanian, R., Nygaard, M. K. E., Sprenger, R. R., Heckmann, A. B., Ostenfeld, M. S., Ejsing, C. S., Eskildsen, S. F., Müllertz, A., Sangild, P. T., Bering, S. B. & Thymann, T., 2021, In: Nutrients. 13, 3, 17 p., 718.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile66 Downloads (Pure) -
Lipid molecular timeline profiling reveals diurnal crosstalk between the liver and circulation
Sprenger, R. R., Hermansson, M., Neess, D., Becciolini, L. S., Sørensen, S. B., Fagerberg, R., Ecker, J., Liebisch, G., Jensen, O. N., Vance, D. E., Færgeman, N. J., Klemm, R. W. & Ejsing, C. S., 2. Feb 2021, In: Cell Reports. 34, 5, 23 p., 108710.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile79 Downloads (Pure) -
2020
Phosphoproteomic Analysis across the Yeast Life Cycle Reveals Control of Fatty Acyl Chain Length by Phosphorylation of the Fatty Acid Synthase Complex
Martínez-Montañés, F., Casanovas, A., Sprenger, R. R., Topolska, M., Marshall, D. L., Moreno-Torres, M., Poad, B. L. J., Blanksby, S. J., Hermansson, M., Jensen, O. N. & Ejsing, C. S., 11. Aug 2020, In: Cell Reports. 32, 6, 108024.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile92 Downloads (Pure) -
2019
Angiotensin-(1-7) oral treatment after experimental myocardial infarction leads to downregulation of CXCR4
Gómez-Mendoza, D. P., Marques, F. D., Melo-Braga, M. N., Sprenger, R. R., Sinisterra, R. D., Kjeldsen, F., Santos, R. A. & Verano-Braga, T., 30. Sept 2019, In: Journal of Proteomics. 208, 11 p., 103486.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile130 Downloads (Pure) -
Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis
Wenning, L., Ejsing, C. S., David, F., Sprenger, R. R., Nielsen, J. & Siewers, V., 11. Mar 2019, In: Microbial Cell Factories. 18, 1, 49.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile133 Downloads (Pure) -
2018
Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Rexen Ulven, E., Milligan, G. & Ulven, T., 8. Nov 2018, In: Journal of Medicinal Chemistry. 61, 21, p. 9534-9550Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile255 Downloads (Pure) -
Organic matter processing by microbial communities throughout the Atlantic water column as revealed by metaproteomics
Bergauer, K., Fernandez-Guerra, A., Garcia, J. A. L., Sprenger, R. R., Stepanauskas, R., Pachiadaki, M. G., Jensen, O. N. & Herndl, G. J., 16. Jan 2018, In: PNAS. 115, 3, p. E400-E408Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile112 Downloads (Pure) -
2017
Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans
Harvald, E. B., Sprenger, R. R., Dall, K. B., Ejsing, C. S., Nielsen, R., Mandrup, S., Murillo, A. B., Larance, M., Gartner, A., Lamond, A. I. & Færgeman, N. J., 2017, In: Cell Systems. 5, 1, p. 38-52.e4Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile214 Downloads (Pure) -
Quantitative lipidomics reveals age-dependent perturbations of whole-body lipid metabolism in ACBP deficient mice
Gallego, S. F., Sprenger, R. R., Neess, D., Pauling, J. K., Færgeman, N. J. & Ejsing, C. S., Feb 2017, In: BBA Molecular and Cell Biology of Lipids. 1862, 2, p. 145-155Research output: Contribution to journal › Journal article › Research › peer-review
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2015
Quantitative analysis of proteome and lipidome dynamics reveals functional regulation of global lipid metabolism
Casanovas, A., Sprenger, R. R., Tarasov, K., Ruckerbauer, D. E., Hannibal-Bach, H. K., Zanghellini, J., Jensen, O. N. & Ejsing, C. S., 19. Mar 2015, In: Chemistry & Biology. 22, 3, p. 412-425 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2014
Microbial stratification in low pH oxic and suboxic macroscopic growths along an acid mine drainage: Microbial stratification in low pH (sub)oxic AMD
Méndez-García, C., Mesa, V., Sprenger, R. R., Richter, M., Diez, M. S., Solano, J., Bargiela, R., Golyshina, O. V., Manteca, A., Ramos, J. L., Gallego, J. R., Llorente, I., Martins Dos Santos, V. A., Jensen, O. N., Peláez, A. I., Sánchez, J. & Ferrer, M., Jun 2014, In: The ISME Journal. 8, p. 1259-1274 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective renal vasoconstriction, exaggerated natriuresis and excretion rates of exosomic proteins in essential hypertension
Damkjaer, M., Jensen, P. H., Schwämmle, V., Sprenger, R. R., Jacobsen, I. A., Jensen, O. N. & Bie, P., Sept 2014, In: Acta Physiologica. 212, 1, p. 106-118 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2013
Deconvolution of mixture spectra and increased throughput of Peptide identification by utilization of intensified complementary ions formed in tandem mass spectrometry
Kryuchkov, F., Verano-Braga, T., Hansen, T. A., Sprenger, R. R. & Kjeldsen, F., 3. Jun 2013, In: Journal of Proteome Research. 12, 7, p. 3362–3371Research output: Contribution to journal › Journal article › Research › peer-review
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Precision mapping of coexisting modifications in histone H3 tails from embryonic stem cells by ETD-MS/MS
Jung, H. R., Sidoli, S., Haldbo, S., Sprenger, R. R., Schwämmle, V., Pasini, D., Helin, K. & Jensen, O. N., 2013, In: Analytical Chemistry. 85, 17, p. 8232–8239Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomics identifies molecular networks affected by tetradecylthioacetic acid and fish oil supplemented diets
Wrzesinski, K., León, I. R., Kulej, K., Sprenger, R. R., Bjørdal , B., Christiansen, B., Berge, R. K., Jensen, O. N. & Rogowska-Wrzesinska, A., 2013, In: Journal of Proteomics. 84, p. 61-77Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative assessment of in-solution digestion efficiency identifies optimal protocols for unbiased protein analysis: Quantitative assessment of protein digestion protocols
Leon, I. R., Schwämmle, V., Jensen, O. N. & Sprenger, R. R., 2013, In: Molecular and Cellular Proteomics. 12, 10, p. 2992-3005Research output: Contribution to journal › Journal article › Research › peer-review
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2011
Determination of the binding sites for oxaliplatin on insulin using mass spectrometry-based approaches
Møller, C., Sprenger, R. R., Stürup, S. & Højrup, P., 19. Jul 2011, In: Analytical and Bioanalytical Chemistry. 401, 5, p. 1623-1633 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2010
Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome
Agar, C., van Os, G. M. A., Mörgelin, M., Sprenger, R., Marquart, J. A., Urbanus, R. T., Derksen, R. H. W. M., Meijers, J. C. M. & de Groot, P. G., 26. Aug 2010, In: Blood. 116, 8, p. 1336-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide alterations in Escherichia coli translation rates upon anaerobiosis
Kramer, G., Sprenger, R., Nessen, M. A., Roseboom, W., Speijer, D., de Jong, L., de Mattos, M. J. T., Back, J. & de Koster, C. G., 1. Nov 2010, In: Molecular and Cellular Proteomics. 9, 11, p. 2508-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomics and the dynamic plasma membrane: Quo Vadis?
Sprenger, R. R. & Jensen, O. N., 1. Nov 2010, In: Proteomics. 10, 22, p. 3997-4011 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2009
Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates
Bussink, A. P., Verhoek, M., Vreede, J., Ghauharali-van der Vlugt, K., Donker-Koopman, W. E., Sprenger, R. R., Hollak, C. E., Aerts, J. M. F. G. & Boot, R. G., 1. Oct 2009, In: The FEBS Journal. 276, 19, p. 5678-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gaucher disease: a model disorder for biomarker discovery
Boot, R. G., van Breemen, M. J., Wegdam, W., Sprenger, R. R., de Jong, S., Speijer, D., Hollak, C. E. M., van Dussen, L., Hoefsloot, H. C. J., Smilde, A. K., de Koster, C. G., Vissers, J. P. C. & Aerts, J. M. F. G., 1. Aug 2009, In: Expert Review of Proteomics. 6, 4, p. 411-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and quantitation of newly synthesized proteins in Escherichia coli by enrichment of azidohomoalanine-labeled peptides with diagonal chromatography
Kramer, G., Sprenger, R. R., Back, J., Dekker, H. L., Nessen, M. A., van Maarseveen, J. H., de Koning, L. J., Hellingwerf, K. J., de Jong, L. & de Koster, C. G., 1. Jul 2009, In: Molecular and Cellular Proteomics. 8, 7, p. 1599-611 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes
Stax, M. J., van Montfort, T., Sprenger, R. R., Melchers, M., Sanders, R. W., van Leeuwen, E., Repping, S., Pollakis, G., Speijer, D. & Paxton, W. A., 1. Sept 2009, In: Virology. 391, 2, p. 203-11 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2008
Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease
Aerts, J. M., van Breemen, M. J., Bussink, A. P., Ghauharali, K., Sprenger, R., Boot, R. G., Groener, J. E., Hollak, C. E., Maas, M., Smit, S., Hoefsloot, H. C., Smilde, A. K., Vissers, J. P., de Jong, S., Speijer, D. & de Koster, C. G., 1. Apr 2008, In: Acta Paediatrica. 97, s457, p. 7-14 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential artefacts in proteome analysis of plasma of Gaucher patients due to protease abnormalities
van Breemen, M. J., Aerts, J. M. F. G., Sprenger, R. R. & Speijer, D., 1. Oct 2008, In: Clinica Chimica Acta. 396, 1-2, p. 26-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2007
A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p
Williams, C., van den Berg, M., Sprenger, R. R. & Distel, B., 3. Aug 2007, In: Journal of Biological Chemistry. 282, 31, p. 22534-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic study of caveolae and rafts isolated from human endothelial cells
Sprenger, R. R. & Horrevoets, A. J. G., 1. Jan 2007, In: Methods in Molecular Biology. 357, p. 199-213 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2006
Spatial segregation of transport and signalling functions between human endothelial caveolae and lipid raft proteomes
Sprenger, R. R., Fontijn, R. D., van Marle, J., Pannekoek, H. & Horrevoets, A. J. G., 15. Dec 2006, In: Biochemical Journal. 400, 3, p. 401-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2004
Comparative proteomics of human endothelial cell caveolae and rafts using two-dimensional gel electrophoresis and mass spectrometry
Sprenger, R. R., Speijer, D., Back, J. W., De Koster, C. G., Pannekoek, H. & Horrevoets, A. J. G., 1. Jan 2004, In: Electrophoresis. 25, 1, p. 156-72 16 p.Research output: Contribution to journal › Journal article › Research › peer-review