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Research Output 1998 2019

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Journal article
2017
89 Downloads (Pure)

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 2017, In : Scientific Reports. 7, 1, 8 p., 8183.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Epigenomics
CpG Islands
Population
DNA Methylation
86 Downloads (Pure)

Lung function discordance in monozygotic twins and associated differences in blood DNA methylation

Bolund, A. C. S., Starnawska, A., Miller, M. R., Schlünssen, V., Backer, V., Børglum, A. D., Christensen, K., Tan, Q., Christiansen, L. & Sigsgaard, T., 2017, In : Clinical Epigenetics (Print). 9, 13 p., 132.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Monozygotic Twins
DNA Methylation
Lung
Epigenomics
Forced Expiratory Volume

The gene expression and immunohistochemical time-course of diphenylcyclopropenone induced contact allergy in healthy humans following repeated epicutaneous challenges

Mose, K. F., Burton, M., Thomassen, M., Andersen, F., Kruse, T. A., Tan, Q., Skov, L., Almose Røpke, M., Litman, T., Clemmensen, O., Kristensen, B. W., S. Friedmann, P. & Andersen, K. E., 2017, In : Experimental Dermatology. 26, 10, p. 926–933

Research output: Contribution to journalJournal articleResearchpeer-review

Hypersensitivity
diphenylcyclopropenone
Polymerase Chain Reaction
Interleukin-17
Gene Expression Profiling
146 Downloads (Pure)

Weighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI.

Wang, W., Jiang, W., Hou, L., Duan, H., Wu, Y., Xu, C., Tan, Q., Li, S. & Zhang, D., 2017, In : BMC Genomics. 18, 17 p., 872.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Monozygotic Twins
Databases
Transcriptome
Chylomicron Remnants
Chylomicrons
2016

Association between the surfactant protein D (SFTPD) gene and subclinical carotid artery atherosclerosis

Sorensen, G. L., Bladbjerg, E. M., Steffensen, R., Tan, Q., Madsen, J., Drivsholm, T. & Holmskov, U., 2016, In : Atherosclerosis. 246, p. 7-12

Research output: Contribution to journalJournal articleResearchpeer-review

Pulmonary Surfactant-Associated Protein D
Single Nucleotide Polymorphism
Smoking
Protein Deficiency

Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins

Starnawska, A., Tan, Q., Lenart, A., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2016, In : Neurobiology of Aging. 50, p. 60-63

Research output: Contribution to journalJournal articleResearchpeer-review

Monozygotic Twins
DNA Methylation
Twin Studies
Epigenomics
Cognition
95 Downloads (Pure)

Change in Depression Symptomatology and Cognitive Function in Twins: A 10-Year Follow-Up Study

Petersen, I., McGue, M., Tan, Q., Christensen, K. & Christiansen, L., Apr 2016, In : Twin Research and Human Genetics. 19, 2, p. 104-111

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
antineoplaston A10
Cognition
Depression
Affective Symptoms
Twin Studies
105 Downloads (Pure)

Comprehensive analysis of high-throughput screens with HiTSeekR

List, M., Schmidt, S., Christiansen, H., Rehmsmeier, M., Tan, Q., Mollenhauer, J. & Baumbach, J., 2016, In : Nucleic Acids Research. 44, 14, p. 6639-6648

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
MicroRNAs
Small Interfering RNA
Clustered Regularly Interspaced Short Palindromic Repeats
Systems Biology
RNA Interference
89 Downloads (Pure)

Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment

Nygaard, M., Debrabant, B., Tan, Q., Deelen, J., Andersen-Ranberg, K., de Craen, A. J. M., Beekman, M., Jeune, B., Slagboom, P. E., Christensen, K. & Christiansen, L., Feb 2016, In : Aging Cell. 15, 1, p. 49-55

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Human Genome
Population
134 Downloads (Pure)

Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study

Svendsen, A. J., Gervin, K., Lyle, R., Christiansen, L., Kyvik, K., Junker, P., Nielsen, C., Houen, G. & Tan, Q., 2016, In : Frontiers in Immunology. 7, 10 p., 510.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Monozygotic Twins
DNA
Smoking
Antirheumatic Agents
DNA Methylation

Differentially Methylated Genomic Regions in Birth-Weight Discordant Twin Pairs

Chen, M., Baumbach, J., Vandin, F., Röttger, R., Vieira Barbosa, E. G., Dong, M., Nielsen, M. F. M., Christiansen, L. & Tan, Q., 2016, In : Annals of Human Genetics. 80, 2, p. 81-87

Research output: Contribution to journalJournal articleResearchpeer-review

DNA Methylation
Epigenomics
Monozygotic Twins
Chromosomes, Human, Pair 1
Health
123 Downloads (Pure)

DNA methylation age is associated with mortality in a longitudinal Danish twin study

Christiansen, L., Lenart, A., Tan, Q., Vaupel, J. W., Aviv, A., McGue, M. & Christensen, K., 2016, In : Aging Cell. 15, 1, p. 149-54

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Twin Studies
DNA Methylation
Survival Analysis
Epigenomics
Longitudinal Studies

Epigenetic drift in the aging genome: a ten-year follow-up in an elderly twin cohort

Tan, Q., Heijmans, B. T., Hjelmborg, J. V. B., Sørensen, M., Christensen, K. & Christiansen, L., 2016, In : International Journal of Epidemiology. 45, 4, p. 1146-1158

Research output: Contribution to journalJournal articleResearchpeer-review

Cytosine
Guanine
Epigenomics
DNA Methylation
Survival Analysis
106 Downloads (Pure)

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

Jelenkovic, A., Hur, Y-M., Sund, R., Yokoyama, Y., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q., Zhang, D., Pang, Z., Aaltonen, S., Heikkilä, K., Öncel, S. Y., Aliev, F., Rebato, E., Tarnoki, A. D., Tarnoki, D. L., Christensen, K., Skytthe, A. & 79 others, Kyvik, K. O., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Cozen, W., Hwang, A. E., Mack, T. M., Sung, J., Song, Y-M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Derom, C. A., Vlietinck, R. F., Loos, R. J., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H-U., Swan, G. E., Krasnow, R., Magnusson, P. K., Pedersen, N. L., Dahl-Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Lichtenstein, P., Spector, T. D., Mangino, M., Lachance, G., Bartels, M., van Beijsterveldt, T. C., Willemsen, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Hjelmborg, J. V. B., Goldberg, J. H., Iwatani, Y., Watanabe, M., Honda, C., Inui, F., Rasmussen, F., Huibregtse, B. M., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J. & Silventoinen, K., 2016, In : eLife. 5, 14 p., e20320.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Far East
North America
Population
82 Downloads (Pure)

Genetic and Environmental Regulation on Longitudinal Change of Metabolic Phenotypes in Danish and Chinese Adult Twins

Li, S., Kyvik, K. O., Pang, Z., Zhang, D., Duan, H., Tan, Q., Hjelmborg, J., Kruse, T. & Dalgård, C., Feb 2016, In : P L o S One. 11, 2, p. 1-14 e0148396.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Environmental regulations
environmental law
Triglycerides
Blood pressure
phenotype

Interaction between FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages

Zeng, Y., Chen, H., Ni, T., Ruan, R., Nie, C., Liu, X., Feng, L., Zhang, F., Lu, J., Li, J., Li, Y., Tao, W., Gregory, S. G., Gottschalk, W., Lutz, M., Land, K., Yashin, A. I., Tan, Q., Yang, Z., Bolund, L. & 9 others, Qi, M., Yang, H., Min, J., Willcox, C. D., Willcox, B., Gu, J., Hauser, E., Tian, X-L. & Vaupel, J. W., Jun 2016, In : Rejuvenation Research. 19, 3, p. 195-203

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Drinking
Alleles
Rejuvenation
Genetic Research
Proportional Hazards Models
62 Downloads (Pure)

Jllumina: A comprehensive Java-based API for statistical Illumina Infinium HumanMethylation450 and MethylationEPIC data processing

Almeida, D. M., Uhrenfeldt Skov, I., Lund, J., Mohammadnejad, A., Silva, A., Vandin, F., Tan, Q., Baumbach, J. & Röttger, R., 2016, In : Journal of Integrative Bioinformatics. 13, 4, 9 p., 294.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Statistical Data Interpretation
Libraries
DNA Methylation
Computational Biology
Epigenomics
81 Downloads (Pure)

Longitudinal Investigation into Genetics in the Conservation of Metabolic Phenotypes in Danish and Chinese Twins

Li, S., Kyvik, K. O., Duan, H., Zhang, D., Pang, Z., Hjelmborg, J., Tan, Q., Kruse, T. & Dalgård, C., 2016, In : P L o S One. 11, 9, p. 1-14 e0162805.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Blood pressure
germplasm conservation
Conservation
phenotype
Blood Glucose
128 Downloads (Pure)

Novel loci and pathways significantly associated with longevity

Zeng, Y., Nie, C., Min, J., Liu, X., Li, M., Chen, H., Xu, H., Wang, M., Ni, T., Li, Y., Yan, H., Zhang, J-P., Song, C., Chi, L-Q., Wang, H-M., Dong, J., Zheng, G-Y., Lin, L., Qian, F., Qi, Y. & 37 others, Liu, X., Cao, H., Wang, Y., Zhang, L., Li, Z., Zhou, Y., Wang, Y., Lu, J., Li, J., Qi, M., Bolund, L., Yashin, A., Land, K. C., Gregory, S., Yang, Z., Gottschalk, W., Tao, W., Wang, J., Wang, J., Xu, X., Bae, H., Nygaard, M., Christiansen, L., Christensen, K., Franceschi, C., Lutz, M. W., Gu, J., Tan, Q., Perls, T., Sebastiani, P., Deelen, J., Slagboom, E., Hauser, E., Xu, H., Tian, X-L., Yang, H. & Vaupel, J. W., Feb 2016, In : Scientific Reports. 6, 13 p., 21243.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Genome-Wide Association Study
Xenobiotics
Sample Size
Single Nucleotide Polymorphism
Interleukin-6
118 Downloads (Pure)

Robust de novo pathway enrichment with KeyPathwayMiner 5

Alcaraz, N., List, M., Dissing-Hansen, M., Rehmsmeier, M., Tan, Q., Mollenhauer, J., Ditzel, H. & Baumbach, J., 2016, In : F1000Research. 2016, 5, 10 p., 1531.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Perturbation techniques
Systems Biology
Computational Biology
Gold
Genes

The epigenomics of polycystic ovarian syndrome: from pathogenesis to clinical manifestations

Li, S., Zhu, D., Duan, H. & Tan, Q., Dec 2016, In : Gynecological Endocrinology. 32, 12, p. 942-946

Research output: Contribution to journalJournal articleResearchpeer-review

Polycystic Ovary Syndrome
Epigenomics
Comorbidity
Ovarian Diseases
Reproductive Health
2015
99 Downloads (Pure)

DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins

Tsai, P-C., Van Dongen, J., Tan, Q., Willemsen, G., Christiansen, L., Boomsma, D. I., Spector, T. D., Valdes, A. M. & Bell, J. T., Dec 2015, In : Twin Research and Human Genetics. 18, 6, p. 635-46

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Monozygotic Twins
DNA Methylation
Meta-Analysis
Low Birth Weight Infant
Metabolic Diseases

Gene, environment and cognitive function: a Chinese twin ageing study

Xu, C., Sun, J., Duan, H., Ji, F., Tian, X., Zhai, Y., Wang, S., Pang, Z., Zhang, D., Zhao, Z., Li, S., Gue, M. M., Hjelmborg, J. V. B., Christensen, K. & Tan, Q., May 2015, In : Age and Ageing. 44, 3, p. 452-457

Research output: Contribution to journalJournal articleResearchpeer-review

Twin Studies
Cognition
Linguistics
Population
Dizygotic Twins

Global Gene Expression Profiling of Telangiectasial Tissue from Patients with Hereditary Haemorrhagic Telangiectasia

Tørring, P. M., Larsen, M. J., Kjeldsen, A. D., Ousager, L. B., Tan, Q. & Brusgaard, K., 2015, In : Microvascular Research. 99, p. 118-126

Research output: Contribution to journalJournal articleResearchpeer-review

GxE Interactions Between FOXO Genotypes and Tea Drinking Significantly Affect Cognitive Disability at Advanced Ages in China

Zeng, Y., Chen, H., Ni, T., Ruan, R., Feng, L., Nie, C., Cheng, L., Li, Y., Tao, W., Gu, J., Land, K. C., Yashin, A., Tan, Q., Yang, Z., Bolund, L., Yang, H., Hauser, E., Willcox, C. D., Willcox, B. J., Tian, X-L. & 1 others, Vaupel, J. W., 2015, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 70, 4, p. 426-433

Research output: Contribution to journalJournal articleResearchpeer-review

Drinking
China
Insurance Benefits
Cognition
Logistic Models
79 Downloads (Pure)
Open Access
File
Long Noncoding RNA
Lymph Nodes
Human Genome
64 Downloads (Pure)

Multivariate Modeling of Body Mass Index, Pulse Pressure, Systolic and Diastolic Blood Pressure in Chinese Twins

Wu, Y., Zhang, D., Pang, Z., Jiang, W., Wang, S., Li, S., von Bornemann Hjelmborg, J. & Tan, Q., Feb 2015, In : Twin Research and Human Genetics. 18, 1, p. 73-78

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Body Mass Index
75 Downloads (Pure)

OpenLabNotes: An Electronic Laboratory Notebook Extension for OpenLabFramework

List, M., Franz, M., Tan, Q., Mollenhauer, J. & Baumbach, J., 2015, In : Journal of Integrative Bioinformatics. 12, 3, 10 p., 274.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
94 Downloads (Pure)

The 82-plex plasma protein signature that predicts increasing inflammation

Tepel, M., Beck, H. C., Tan, Q., Borst, C. & Rasmussen, L. M., 2015, In : Scientific Reports. 5, 12 p., 14882.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Proteome
Tandem Mass Spectrometry
Computational Biology
Liquid Chromatography
Proteins
95 Downloads (Pure)

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A. & 106 others, Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D'Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Hong, C., Chong, Y., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y-M., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Rasmussen, F., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Boomsma, D. I., Hur, Y-M., Sørensen, T. I. A. & Kaprio, J., Aug 2015, In : Twin Research and Human Genetics. 18, 4, p. 348-360

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Twin Studies
Smoking
Education
Dizygotic Twins
Weights and Measures
72 Downloads (Pure)

The genetic basis for cognitive ability, memory, and depression symptomatology in middle-aged and elderly chinese twins

Xu, C., Sun, J., Ji, F., Tian, X., Duan, H., Zhai, Y., Wang, S., Pang, Z., Zhang, D., Zhao, Z., Li, S., Hjelmborg, J. V. B., Christensen, K. & Tan, Q., Feb 2015, In : Twin Research and Human Genetics. 18, 1, p. 79-85

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Depression
Cognition
Geriatrics
Population
Multivariate Analysis
88 Downloads (Pure)

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project

Jelenkovic, A., Yokoyama, Y., Sund, R., Honda, C., Bogl, L. H., Aaltonen, S., Ji, F., Ning, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M. & 110 others, Saudino, K. J., Dubois, L., Boivin, M., Tarnoki, A. D., Tarnoki, D. L., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D'Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Kim, B., Chong, Y., Hong, C., Shin, H. J., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y-M., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Rasmussen, F., Hur, Y-M., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J. & Silventoinen, K., Oct 2015, In : Twin Research and Human Genetics. 18, 5, p. 557-70

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Monozygotic Twins
Dizygotic Twins
Body Mass Index
Databases
2014
Genes
Alleles
Genetic Heterogeneity
Medical Genetics
Population

Classification of Breast Cancer Subtypes by combining Gene Expression and DNA Methylation Data

List, M., Hauschild, A-C., Tan, Q., Kruse, T. A., Mollenhauer, J., Baumbach, J. & Batra, R., Jun 2014, In : Journal of Integrative Bioinformatics. 11, 2, p. 236

Research output: Contribution to journalJournal articleResearchpeer-review

DNA Methylation
Epigenomics
Gene Expression Profiling
Databases

Contribution of genetic polymorphisms on functional status at very old age: A gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway

Dato, S., Sørensen, M., Lagani, V., Montesanto, A., Passarino, G., Christensen, K., Tan, Q. & Christiansen, L., Apr 2014, In : Experimental Gerontology. 52, p. 23-29

Research output: Contribution to journalJournal articleResearchpeer-review

Oxidative stress
Genetic Polymorphisms
Polymorphism
Single Nucleotide Polymorphism
Genes

Efficient Sample Tracking With OpenLabFramework

List, M., Schmidt, S., Trojnar, J., Thomas, J., Thomassen, M., Kruse, T. A., Tan, Q., Baumbach, J. & Mollenhauer, J., Mar 2014, In : Scientific Reports. 4, 4278.

Research output: Contribution to journalJournal articleResearchpeer-review

Clinical Laboratory Information Systems
Information Management
Libraries
Biomedical Research
Clone Cells

Epigenetic signature of birth weight discordance in adult twins

Tan, Q., Nielsen, M. F. M., Heijmans, B. T., von Bornemann Hjelmborg, J., Tobi, E. W., Christensen, K. & Christiansen, L., Dec 2014, In : B M C Genomics. 15, 1062.

Research output: Contribution to journalJournal articleResearchpeer-review

Epigenomics
Monozygotic Twins
Health
Low Birth Weight Infant
Proxy

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

Deelen, J., Beekman, M., Uh, H-W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guðbjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., van den Akker, E. B., Böhringer, S. & 67 others, Helmer, Q., Nelson, C. P., Saunders, G. I., Alver, M., Andersen-Ranberg, K., Breen, M. E., van der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J. C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E. J. C., Harrow, J., van Heemst, D., Heijmans, B. T., Heinsen, F-A., Hottenga, J-J., Hofman, A., Jeune, B., Jonsson, P. V., Lathrop, M., Lechner, D., Martin-Ruiz, C., McNerlan, S. E., Mihailov, E., Montesanto, A., Mooijaart, S. P., Murphy, A., Nohr, E. A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O. A., Salvioli, S., Sattar, N., Schreiber, S., Stefánsson, H., Stott, D. J., Tiemeier, H., Uitterlinden, A. G., Westendorp, R. G. J., Willemsen, G., Samani, N. J., Galan, P., Sørensen, T. I. A., Boomsma, D. I., Jukema, J. W., Rea, I. M., Passarino, G., de Craen, A. J. M., Christensen, K., Nebel, A., Stefánsson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T. B. L., van Duijn, C. M., Franceschi, C., Houwing-Duistermaat, J. J. & Slagboom, P. E., Aug 2014, In : Human Molecular Genetics. 23, 16, p. 4420-32

Research output: Contribution to journalJournal articleResearchpeer-review

Genome-Wide Association Study
Meta-Analysis
Alleles
Population

Human longevity and variation in DNA damage response and repair: Study of the contribution of sub-processes using competitive gene-set analysis

Debrabant, B., Sørensen, M., Flachsbart, F., Dato, S., Mengel-From, J., Stevnsner, T., Bohr, V. A., Kruse, T. A., Schreiber, S., Nebel, A., Christensen, K., Tan, Q. & Christiansen, L., Sep 2014, In : European Journal of Human Genetics. 22, 9, p. 1131-6

Research output: Contribution to journalJournal articleResearchpeer-review

Recombinational DNA Repair
Single Nucleotide Polymorphism
DNA Mismatch Repair
Telomere
Population

Long non-coding RNA expression profiles in hereditary haemorrhagic telangiectasia

Tørring, P. M., Larsen, M. J., Kjeldsen, A. D., Ousager, L. B., Tan, Q. & Brusgaard, K., 2014, In : PLOS ONE. 9, 3, e90272.

Research output: Contribution to journalJournal articleResearchpeer-review

Long Noncoding RNA
transcriptome
probes (equipment)
Tissue
Microarrays
Microarrays
Gene expression
RNA
Genes
Essential Genes

Microarray R-based analysis of complex lysate experiments with MIRACLE

List, M., Block, I., Pedersen, M. L., Christiansen, H., Schmidt, S., Thomassen, M., Tan, Q., Baumbach, J. & Mollenhauer, J., Sep 2014, In : Bioinformatics. 30, 17, p. i631-i638

Research output: Contribution to journalJournal articleResearchpeer-review

Protein Array Analysis
Proteins
Metrorrhagia
Computational Biology
Health

Power Estimation for Gene-Longevity Association Analysis Using Concordant Twins

Tan, Q., Zhao, J. H., Kruse, T. A. & Christensen, K., 2014, In : Genetics Research International. 2014, 8 p., 154204.

Research output: Contribution to journalJournal articleResearchpeer-review

Genetic Association Studies
Sample Size
Dizygotic Twins
Monozygotic Twins
Computer Simulation

Probing genetic overlap in the regulation of systolic and diastolic blood pressure in Danish and Chinese twins

Li, S., Pang, Z., Zhang, D., Duan, H., von Bornemann Hjelmborg, J., Tan, Q., Kruse, T. A. & Kyvik, K. O., Oct 2014, In : Hypertension Research. 37, 10, p. 954-9

Research output: Contribution to journalJournal articleResearchpeer-review

Confidence Intervals
Publications
Research
Population

RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families

Larsen, M. J., Thomassen, M., Tan, Q., Lænkholm, A. V., Bak, M., Sørensen, K. P., Andersen, M. K., Kruse, T. A. & Gerdes, A-M., 2014, In : B M C Medical Genomics. 7, p. 9 9.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
RNA
Neoplasms
Mutation
Penetrance
Germ-Line Mutation

Surfactant Protein-D-Encoding Gene Variant Polymorphisms Are Linked to Respiratory Outcome in Premature Infants

Sorensen, G. L., Dahl, M., Tan, Q., Bendixen, C., Holmskov, U. & Husby, S., 8. Jul 2014, In : Journal of Pediatrics. 165, 4, p. 683–689

Research output: Contribution to journalJournal articleResearchpeer-review

Pulmonary Surfactant-Associated Protein D
Premature Infants
Single Nucleotide Polymorphism
Haplotypes
Oxygen

Surfactant Protein D is a candidate biomarker for subclinical tobacco smoke-induced lung damage

Lock Johansson, S., Tan, Q., Holst, R., Christiansen, L., Hansen, N. C., Hojland, A. T., Wulf-Johansson, H., Schlosser, A., Titlestad, I. L., Vestbo, J., Holmskov, U., Kyvik, K. O. & Sorensen, G. L., May 2014, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 306, 9, p. L887-L895

Research output: Contribution to journalJournal articleResearchpeer-review

Pulmonary Surfactant-Associated Protein D
Smoke
Lung
Single Nucleotide Polymorphism
Smoking
Aromatase
Polycystic Ovary Syndrome
Androgen Receptors
Gene expression
Insulin Resistance
2013

AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians

Nygaard, M., Soerensen, M., Flachsbart, F., Mengel-From, J., Tan, Q., Schreiber, S., Nebel, A., Christensen, K. & Christiansen, L., 2013, In : European Journal of Human Genetics. 21, 5, p. 574-577

Research output: Contribution to journalJournal articleResearchpeer-review

Single Nucleotide Polymorphism
Medical Genetics
Population
Publications
Longitudinal Studies
Deceleration
Alleles
Cohort Effect
Genetic Models