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Research Output 1998 2019

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Journal article

[Heritability analysis on serum lipids of adult twins in Qingdao City]: Article in Chinese

Translated title of the contribution: [Heritability analysis on serum lipids of adult twins in Qingdao City]Lan, J., Pang, Z., Wang, S., Zhang, H., Duan, H., Zhang, D., Tan, Q. & Zhang, D., 1. May 2010, In : Weisheng Yanjiu. 39, 3, p. 291-4 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

LDL Cholesterol
HDL Cholesterol
Lipids
Serum
Fasting
Case-Control Studies

A centenarian-only approach for assessing gene-gene interaction in human longevity

Tan, Q., De Benedictis, G., Ukraintseva, S. V., Franceschi, C., Vaupel, J. W. & Yashin, A. I., 2002, In : European Journal of Human Genetics. 10(2), p. 119-24

Research output: Contribution to journalJournal articleResearchpeer-review

Haplotypes
Mitochondrial Genes
Alleles
Population

A combinatory approach for selecting prognostic genes in microarray studies of tumour survivals

Tan, Q., Thomassen, M., Jochumsen, K. M., Mogensen, O., Christensen, K. & Kruse, T. A., 2009, In : Advances in Bioinformatics. 2009, p. 480-486 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Microarrays
Tumors
Genes
Gene expression
Feature extraction

A cross-sectional analysis of age and sex patterns in grip strength, tooth loss, near vision and hearing levels in Chinese aged 50-74 years

Wu, Y., Pang, Z., Zhang, D., Jiang, W., Wang, S., Li, S., Kruse, T. A., Christensen, K. & Tan, Q., 3. Sep 2012, In : Archives of Gerontology and Geriatrics. 54, 2, p. e213-e220

Research output: Contribution to journalJournal articleResearchpeer-review

Tooth Loss
Hearing
Cross-Sectional Studies
Sex Characteristics
Visual Acuity

Adenoid cystic carcinomas of the salivary gland, lacrimal gland, and breast are morphologically and genetically similar but have distinct microRNA expression profiles

Andreasen, S., Tan, Q., Agander, T. K., Steiner, P., Bjørndal, K., Høgdall, E., Larsen, S. R., Erentaite, D., Olsen, C. H., Ulhøi, B. P., von Holstein, S. L., Wessel, I., Heegaard, S. & Homøe, P., Aug 2018, In : Modern Pathology. 31, 8, p. 1211–1225

Research output: Contribution to journalJournal articleResearchpeer-review

Lacrimal Apparatus
Adenoid Cystic Carcinoma
MicroRNAs
Neoplasms
Glandular and Epithelial Neoplasms
33 Downloads (Pure)

Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

Lund, J. B., Li, S., Christensen, K., Mengel-From, J., Thinggaard, M. S., Marioni, R. E., Starr, J., Pattie, A., Deary, I. J., Baumbach, J. & Tan, Q., 2019, In : Aging Cell. 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
DNA Methylation
Epigenomics
Sex Characteristics

A genome-wide association study of cognitive function in Chinese adult twins

Xu, C., Zhang, D., Wu, Y., Tian, X., Pang, Z., Li, S. & Tan, Q., 2017, In : Biogerontology. 18, 5, p. 811–819

Research output: Contribution to journalJournal articleResearchpeer-review

Genome-Wide Association Study
Cognition
Single Nucleotide Polymorphism
Dizygotic Twins
Metabolic Diseases

A genome-wide linkage search for bipolar disorder susceptibility loci in a large and complex pedigree from the eastern part of Cuba

Marcheco-Teruel, B., Flint, T. J., Wikman, F. P., Torralbas, M., Gonzalez, L., Blanco, L., Tan, Q., Ewald, H., Ørntoft, T., Kruse, T., Børglum, A. D. & Mors, O., 2006, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 141B, 8, p. 833-843

Research output: Contribution to journalJournal articleResearchpeer-review

A growth curve model with fractional polynomials for analysing incomplete time-course data in microarray gene expression studies

Tan, Q., Thomassen, M., Hjelmborg, J. V. B., Clemmensen, A., Andersen, K. E., Petersen, T. K., McGue, M., Christensen, K. & Kruse, T. A., 27. Sep 2011, In : Advances in Bioinformatics. 2011, Article ID 261514, 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Microarrays
Gene expression
Genes
Polynomials
Growth

AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians

Nygaard, M., Soerensen, M., Flachsbart, F., Mengel-From, J., Tan, Q., Schreiber, S., Nebel, A., Christensen, K. & Christiansen, L., 2013, In : European Journal of Human Genetics. 21, 5, p. 574-577

Research output: Contribution to journalJournal articleResearchpeer-review

Single Nucleotide Polymorphism
Medical Genetics
Population
Publications

A logistic regression model for measuring gene-longevity associations

Tan, Q., Yashin, A. I., De Benedictis, G., Cintolesi, F., Rose, G., Bonafe, M., Francheschi, C., Vach, W. & Vaupel, J. W., 2001, In : Clinical Genetics. 60, p. 463-469

Research output: Contribution to journalJournal articleResearchpeer-review

Logistic Models
Research
Longitudinal Studies
Deceleration
Alleles
Cohort Effect
Genetic Models

A non-parametric approach for identifying differentially expressed genes in factorial microarray experiments

Tan, Q., Dahlgaard, J., Kassem, M., Vach, W. & Kruse, T., 2005, In : Genome Biology. 6, 4, p. 5

Research output: Contribution to journalJournal articleResearchpeer-review

A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family

Tan, Q., Sørensen, M., Kruse, T. A., Christensen, K. & Christiansen, L., 2013, In : Aging Cell. 12, 4, p. 690-694

Research output: Contribution to journalJournal articleResearchpeer-review

Single Nucleotide Polymorphism
Population
Datasets

Anti-Inflammatory Heat Shock Protein 70 Genes are Positively Associated with Human Survival

Singh, R., Kølvraa, S., Bross, P. G., Christensen, K., Bathum, L., Gregersen, N., Tan, Q. & Rattan, S., 2010, In : Current Pharmaceutical Design. 16, 7, p. 796-801 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

HSP70 Heat-Shock Proteins
Haplotypes
Heat-Shock Response
Survival Analysis
Single Nucleotide Polymorphism

Apolipoprotein E genotype frequency patterns in aged Danes as revealed by logistic regression models

Tan, Q., Christiansen, L., Christensen, K., Kruse, T. & Bathum, L., 2004, In : European Journal of Epidemiology. 19, 7, p. 651-656

Research output: Contribution to journalJournal articleResearchpeer-review

Logistic Models
Alleles
Dominant Genes
Research Design
Age Groups

Arrayed primer extension in the "array of arrays" format: a rational approach for microarray-based SNP genotyping

Klitø, N. G. F., Tan, Q., Nyegaard, M., Brusgaard, K., Thomassen, M., Skouboe, C., Dahlgaard, J. & Kruse, T. A., 1. Jan 2007, In : Genetic Testing. 11, 2, p. 160-6 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Linkage Disequilibrium
HapMap Project
Chromosome Mapping
Databases
Population

Assessing genetic association with human survival at multi-allelic loci

Tan, Q., De Benedictis, G., Yashin, I. A., Bathum, L., Christiansen, L., Dahlgaard, J., Frizner, N., Vach, W., Vaupel, J. W., Christensen, K. & Kruse, T., 2004, In : Biogerontology. 5, 2, p. 89-97

Research output: Contribution to journalJournal articleResearchpeer-review

Alleles
Genetic Selection
Survival Analysis
Renin
Research

Association between the surfactant protein D (SFTPD) gene and subclinical carotid artery atherosclerosis

Sorensen, G. L., Bladbjerg, E. M., Steffensen, R., Tan, Q., Madsen, J., Drivsholm, T. & Holmskov, U., 2016, In : Atherosclerosis. 246, p. 7-12

Research output: Contribution to journalJournal articleResearchpeer-review

Pulmonary Surfactant-Associated Protein D
Single Nucleotide Polymorphism
Smoking
Protein Deficiency
68 Downloads (Pure)

Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts

Piirtola, M., Jelenkovic, A., Latvala, A., Sund, R., Honda, C., Inui, F., Watanabe, M., Tomizawa, R., Iwatani, Y., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Tarnoki, A. D., Tarnoki, D. L., Martin, N. G., Montgomery, G. W., Medland, S. E., Rasmussen, F., Tynelius, P., Tan, Q. & 30 others, Zhang, D., Pang, Z., Rebato, E., Stazi, M. A., Fagnani, C., Brescianini, S., Busjahn, A., Harris, J. R., Brandt, I., Nilsen, T. S., Cutler, T. L., Hopper, J. L., Corley, R. P., Huibregtse, B. M., Sung, J., Kim, J., Lee, J., Lee, S., Gatz, M., Butler, D. A., Franz, C. E., Kremen, W. S., Lyons, M. J., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Öncel, S. Y., Aliev, F., Derom, C. A. & Vlietinck, R. F., 2018, In : PLOS ONE. 13, 7, 17 p., e0200140.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
body mass index
Body Mass Index
Smoking
confidence interval
Confidence Intervals
116 Downloads (Pure)

Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer

Block, I., Burton, M., Sørensen, K. P., Andersen, L., Larsen, M. J., Bak, M., Cold, S., Thomassen, M., Tan, Q. & Kruse, T. A., 6. Feb 2018, In : OncoTarget. 9, 10, p. 9030-9042

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hirsutism
Polycystic Ovary Syndrome
Single Nucleotide Polymorphism
Referral and Consultation
Endocrine System Diseases

Association of serum uric acid level with muscle strength and cognitive function among Chinese aged 50-74 years

Wu, Y., Zhang, D., Pang, Z., Jiang, W., Wang, S. & Tan, Q., 2013, In : Geriatrics & Gerontology International. 13, 3, p. 672-677

Research output: Contribution to journalJournal articleResearchpeer-review

Uric Acid
Cognition
regression
comorbidity
Caucasian

Atopic dermatitis: a total genome-scan for susceptibility genes

Haagerup, A., Bjerke, T., Schiøtz, P. O., Dahl, R., Binderup, H. G., Tan, Q. & Kruse, T. A., 2004, In : Acta Dermato-Venereologica. 84, 5, p. 346-352

Research output: Contribution to journalJournal articleResearchpeer-review

Atopic Dermatitis
Hypersensitivity
Genetic Research
Incidence
Genes
Alleles
Genetic Heterogeneity
Medical Genetics
Population

Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins

Starnawska, A., Tan, Q., Lenart, A., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2016, In : Neurobiology of Aging. 50, p. 60-63

Research output: Contribution to journalJournal articleResearchpeer-review

Monozygotic Twins
DNA Methylation
Twin Studies
Epigenomics
Cognition

Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population

Christiansen, L., Tan, Q., Iachina, M., Bathum, L., Kruse, T., McGue, M. & Christensen, K., 2006, In : Biological Psychiatry. 61, 2, p. 223-239

Research output: Contribution to journalJournal articleResearchpeer-review

Depression
Population
Vesicular Monoamine Transport Proteins
Haplotypes
Depression
Chromosomes, Human, Pair 12
Longitudinal Studies
Reference Values
95 Downloads (Pure)

Change in Depression Symptomatology and Cognitive Function in Twins: A 10-Year Follow-Up Study

Petersen, I., McGue, M., Tan, Q., Christensen, K. & Christiansen, L., Apr 2016, In : Twin Research and Human Genetics. 19, 2, p. 104-111

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
antineoplaston A10
Cognition
Depression
Affective Symptoms
Twin Studies

Circulating, Cell-Free Micro-RNA Profiles Reflect Discordant Development of Dementia in Monozygotic Twins

Mengel-From, J., Rønne, M. E., Carlsen, A. L., Skogstrand, K., Larsen, L. A., Tan, Q., Christiansen, L., Christensen, K. & Heegaard, N. H. H., 1. Jan 2018, In : Journal of Alzheimer's disease : JAD. 63, 2, p. 591-601

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Monozygotic Twins
MicroRNAs
Immunoassay
Lipoproteins
Longitudinal Studies

Circulating microRNAs disclose biology of normal cognitive function in healthy elderly people – a discovery twin study

Mengel-From, J., Feddersen, S., Halekoh, U., Heegaard, N. H. H., McGue, M., Christensen, K., Tan, Q. & Christiansen, L., Sep 2018, In : European Journal of Human Genetics. 26, 9, p. 1378–1387

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Twin Studies
MicroRNAs
Cognition
Neurobiology
Monozygotic Twins

Circulating surfactant protein D is associated to mortality in elderly women: A twin study

Johansson, H. W., Thinggaard, M., Tan, Q., Johansson, S. L., Schlosser, A., Christensen, K., Holmskov, U. & Sorensen, G. L., 2013, In : Immunobiology. 218, 5, p. 712-717

Research output: Contribution to journalJournal articleResearchpeer-review

Pulmonary Surfactant-Associated Protein D
Twin Studies
Confidence Intervals
Lung
Survival Analysis

Classification of Breast Cancer Subtypes by combining Gene Expression and DNA Methylation Data

List, M., Hauschild, A-C., Tan, Q., Kruse, T. A., Mollenhauer, J., Baumbach, J. & Batra, R., Jun 2014, In : Journal of Integrative Bioinformatics. 11, 2, p. 236

Research output: Contribution to journalJournal articleResearchpeer-review

DNA Methylation
Epigenomics
Gene Expression Profiling
Databases

Classifications within Molecular Subtypes Enables Identification of BRCA1/BRCA2 Mutation Carriers by RNA Tumor Profiling

Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, A-V., Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, T. V. O., Ejlertsen, B., Gerdes, A-M. & Thomassen, M., 2013, In : P L o S One. 8, 5, p. e64268

Research output: Contribution to journalJournal articleResearchpeer-review

Tumors
RNA
mutation
Mutation
neoplasms

Combined experimental and statistical strategy for mass spectrometry based serum protein profiling for diagnosis of breast cancer: a case-control study

Callesen, A. K., Vach, W., Jørgensen, P. E., Cold, S., Tan, Q., Depont Christensen, R., Mogensen, O., Kruse, T., Madsen, J. S. & Jensen, O. N., 1. Apr 2008, In : Journal of Proteome Research. 7, 4, p. 1419-1426 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Mass spectrometry
Case-Control Studies
Blood Proteins
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Serum

Combining genetic and demographic information in population studies of aging and longevity

Yashin, AI., Vaupel, JW., Andereev, AF., Tan, Q., Iachine, IA., Carotenuto, L., De Benedictis, G., Bonafe, M., Valensin, S. & Franceschi, C., 1998, In : Journal of Epidemiology and Biostatistics. 3, 3, p. 289-294 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparison of gene sets for expression profiling: prediction of metastasis from low-malignant breast cancer

Thomassen, M., Tan, Q., Eiriksdottir, F., Bak, M., Cold, S. & Kruse, T. A., 15. Sep 2007, In : Clinical Cancer Research. 13, 18 Pt 1, p. 5355-5360 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Gene Expression Profiling
Neoplasms
105 Downloads (Pure)

Comprehensive analysis of high-throughput screens with HiTSeekR

List, M., Schmidt, S., Christiansen, H., Rehmsmeier, M., Tan, Q., Mollenhauer, J. & Baumbach, J., 2016, In : Nucleic Acids Research. 44, 14, p. 6639-6648

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
MicroRNAs
Small Interfering RNA
Clustered Regularly Interspaced Short Palindromic Repeats
Systems Biology
RNA Interference

Contribution of genetic polymorphisms on functional status at very old age: A gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway

Dato, S., Sørensen, M., Lagani, V., Montesanto, A., Passarino, G., Christensen, K., Tan, Q. & Christiansen, L., Apr 2014, In : Experimental Gerontology. 52, p. 23-29

Research output: Contribution to journalJournal articleResearchpeer-review

Oxidative stress
Genetic Polymorphisms
Polymorphism
Single Nucleotide Polymorphism
Genes
86 Downloads (Pure)

Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment

Nygaard, M., Debrabant, B., Tan, Q., Deelen, J., Andersen-Ranberg, K., de Craen, A. J. M., Beekman, M., Jeune, B., Slagboom, P. E., Christensen, K. & Christiansen, L., Feb 2016, In : Aging Cell. 15, 1, p. 49-55

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Human Genome
Population

Correspondance analysis of microarray time-course data in case control design

Tan, Q., Brusgaard, K., Kruse, T., Oakley, E., Hemmings, B., Beck-Nielsen, H., Hansen, L. & Gaster, M., 2004, In : Journal of Biomedical Informatics. 37, p. 358-365

Research output: Contribution to journalJournal articleResearchpeer-review

Design and analysis in genetic studies of human ageing and longevity

Tan, Q., Kruse, T. & Christensen, K., 2006, In : Ageing Research Reviews. 5, 4, p. 371-387

Research output: Contribution to journalJournal articleResearchpeer-review

Medical Genetics
Genotyping Techniques
Aging of materials
Human Genome Project
Sampling Studies

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: An individual-based pooled analysis of 40 twin cohorts

Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietilainen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 others, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Oncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Song, Y. M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H. U., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 2017, In : American Journal of Clinical Nutrition. 106, 2, p. 457-466

Research output: Contribution to journalJournal articleResearchpeer-review

Far East
North America
Body Mass Index
Population

Differential and correlation analyses of microarray gene expression data in the CEPH Utah families

Tan, Q., Zhao, J., Li, S., Christiansen, L., Kruse, T. & Christensen, K., 1. Aug 2008, In : Genomics. 92, 2, p. 94-100 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

X Chromosome Inactivation
Age Groups
Medicine
161 Downloads (Pure)

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

Li, S., Zhu, D., Duan, H., Ren, A., Glintborg, D., Andersen, M., Skov, V., Thomassen, M., Kruse, T. & Tan, Q., 2017, In : Oncotarget. 8, 13, p. 20656-20666

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Polycystic Ovary Syndrome
DNA Methylation
Epigenomics
Prolactin
DNA
82 Downloads (Pure)

Differential effect of surgical manipulation on gene expression in normal breast tissue and breast tumor tissue

Pedersen, I. S., Thomassen, M., Tan, Q., Kruse, T. A., Thorlacius-Ussing, O., Garne, J. P. & Krarup, H. B., 16. Nov 2018, In : Molecular Medicine. 24, 8 p., 57.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neoplasms
Gene Expression Profiling
Transcriptome
Freezing
134 Downloads (Pure)

Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study

Svendsen, A. J., Gervin, K., Lyle, R., Christiansen, L., Kyvik, K., Junker, P., Nielsen, C., Houen, G. & Tan, Q., 2016, In : Frontiers in Immunology. 7, 10 p., 510.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Monozygotic Twins
DNA
Smoking
Antirheumatic Agents
DNA Methylation

Differentially Methylated Genomic Regions in Birth-Weight Discordant Twin Pairs

Chen, M., Baumbach, J., Vandin, F., Röttger, R., Vieira Barbosa, E. G., Dong, M., Nielsen, M. F. M., Christiansen, L. & Tan, Q., 2016, In : Annals of Human Genetics. 80, 2, p. 81-87

Research output: Contribution to journalJournal articleResearchpeer-review

DNA Methylation
Epigenomics
Monozygotic Twins
Chromosomes, Human, Pair 1
Health
79 Downloads (Pure)

Disease-Concordant Twins Empower Genetic Association Studies

Tan, Q., Li, W. & Vandin, F., Jan 2017, In : Annals of Human Genetics. 81, 1, p. 20-26

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Genetic Association Studies
Dizygotic Twins
Sample Size
Monozygotic Twins
Diseases in Twins