Peter Højrup

ph.d.

  • Campusvej 55

    5230 Odense M

    Denmark

1982 …2020
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Research Output 1982 2020

2011

Assessing high affinity binding to HLA-DQ2.5 by a novel peptide library based approach

Jüse, U., Arntzen, M., Højrup, P., Fleckenstein, B. & Sollid, L. M., 1. Apr 2011, In : Bioorganic & Medicinal Chemistry. 19, 7, p. 2470-7 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Peptide Library
Libraries
Mass spectrometry
Search Engine
Peptides

Calreticulin interacts with exposed disulfide bridges

Møllegaard, K. M., Sørensen, K. D., Højrup, P. & Houen, G., 30. Aug 2011. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Chemical cross-linking as abasis for modelling multimeric calreticulin

Refsgaard, J. C., Peng, L., Rasmussen, M., Houen, G. & Højrup, P., 30. Aug 2011. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

CrossWork: Software-assisted identification of cross-linked peptides

Rasmussen, M., Refsgaard, J., Peng, L., Houen, G. & Højrup, P., 2011, In : Journal of Proteomics. 74, 10, p. 1871-1883 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Determination of the binding sites for oxaliplatin on insulin using mass spectrometry-based approaches

Møller, C., Sprenger, R. R., Stürup, S. & Højrup, P., 19. Jul 2011, In : Analytical and Bioanalytical Chemistry. 401, 5, p. 1623-1633 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

oxaliplatin
Insulin
Binding sites
Mass spectrometry
Binding Sites

Gel-shift assay for demonstrating calreticulin substrate interactions

Boelt, S. G., Højrup, P. & Houen, G., 30. Aug 2011. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Human inter-α-inhibitor is a substrate for factor XIIIa and tissue transglutaminase

Sonne-Schmidt, C. S., Sanggaard, K. W., Nikolajsen, C. L., Bak, S., Valnickova, Z., Thøgersen, I., Jensen, O. N., Højrup, P. & Enghild, J. J., 2011, In : BBA General Subjects. 1814, 12, p. 1624-1630

Research output: Contribution to journalJournal articleResearchpeer-review

Factor XIIIa
Fibrin
Substrates
Proteolysis
Antifibrinolytic Agents

MassAI - a New Tool for Protein Identification and Scan Annotation of Mass-spectrometric Datasets

Rasmussen, M. & Højrup, P., 7. Jun 2011.

Research output: Contribution to conference without publisher/journalPosterResearch

Purification and characterization of a soluble calnexin from human placenta

Olsen, D. T., Peng, L., Højrup, P. & Houen, G., 30. Aug 2011. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Quantitative proteomics by amino acid labeling in C. elegans

Fredens, J., Engholm-Keller, K., Giessing, A., Pultz, D., Larsen, M. R., Højrup, P., Møller-Jensen, J. & Færgeman, N. J., 2011, In : Nature Methods. 8, 10, p. 845-847

Research output: Contribution to journalJournal articleResearchpeer-review

Caenorhabditis elegans
Isotopes
Labeling
Amino Acids
Gene Knockdown Techniques

Salivary tissue inhibitor of metalloproteinases-1 localization and glycosylation profile analysis

Holten-Andersen, L., Thaysen-Andersen, M., Jensen, S. B., Buchwald, C., Højrup, P., Offenberg, H., Nielsen, H. J., Brünner, N. A., Nauntofte, B. & Reibel, J., 1. Nov 2011, In : APMIS Supplementum. 119, 11, p. 741-749 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Tissue Inhibitor of Metalloproteinase-1
Glycosylation
Saliva
Parotid Gland
Messenger RNA

Simultaneous glycan-peptide characterization using hydrophilic interaction chromatography and parallel fragmentation by CID, HCD and ETD-MS applied to the N-linked glycoproteome of Campylobacter jejuni

Scott, N. E., Parker, B. L., Connolly, A. M., Paulech, J., Edwards, A. V. G., Crossett, B., Falconer, L., Kolarich, D., Djordjevic, S. P., Højrup, P., Packer, N. H., Larsen, M. R. & Cordwell, S. J., 2011, In : Molecular and Cellular Proteomics. 10, 2, p. M000031-MCP201

Research output: Contribution to journalJournal articleResearchpeer-review

Campylobacter jejuni
Chromatography
Glycosylation
Polysaccharides
Electrons

Structural characteristics of a novel antifreeze protein from the longhorn beetle Rhagium inquisitor

Kristiansen, E., Ramløv, H., Højrup, P., Pedersen, S. A., Hagen, L. & Zachariassen, K. E., 12. Nov 2011, In : Insect Biochemistry and Molecular Biology. 41, 2, p. 109-117

Research output: Contribution to journalJournal articleResearchpeer-review

Rhagium
Antifreeze Proteins
Coleoptera
Insect Proteins
insect proteins

The interactions of calreticulin with immunoglobulin G and immunoglobulin

Møllegaard, K. M., Sørensen, K. D., Træholt, S. D., Thaysen-Andersen, M., Liu, Y., Palma, A. S., Feizi, T., Hansen, P. R., Højrup, P. & Houen, G., 2011. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

The interactions of calreticulin with immunoglobulin G and immunoglobulin Y

Møllegaard, K. M., Duus, K., Træholt, S. D., Thaysen-Andersen, M., Liu, Y., Palma, A. S., Feizi, T., Hansen, P. R., Højrup, P. & Houen, G., 2011, In : BBA General Subjects. 1814, 7, p. 889-99 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Calreticulin
Immunoglobulin G
Peptides
Mannose
Oligosaccharides
2010

Analysis of Cross-linked Glycoproteins Through Mass Spectroscopy and Bioinformatics – Retaining Both Protein and Glycan Structural Information

Rasmussen, M., Neves-Ferreira, A. & Højrup, P., 24. May 2010.

Research output: Contribution to conference without publisher/journalPosterResearch

Assembly of the ERp72 Domains Through Cross-linking and Mass-spectrometry

Rasmussen, M., Nielsen, J. CR., Peng, L., Houen, G. & Højrup, P., 7. Dec 2010.

Research output: Contribution to conference without publisher/journalPosterResearch

Combining CID and HCD Fragmentation with Bioinformatics Facilitates the Automated Identification of N-linked Glycoproteins in Complex Protein Mixtures.

Rasmussen, M., Thaysen-Andersen, M., Mysling, S. & Højrup, P., 23. May 2010.

Research output: Contribution to conference without publisher/journalPosterResearch

Cyclization of the N-Terminal X-Asn-Gly Motif during Sample Preparation for Bottom-Up Proteomics

Zhang, X. & Højrup, P., 2010, In : Analytical Chemistry. 82, 20, p. 8680-8685

Research output: Contribution to journalJournal articleResearchpeer-review

Cyclization
Peptides
Proteomics
Glutamine
227 Downloads (Pure)

Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections

Olesen, C. H., Brahimi, K., Vandahl, B., Lousada-Dietrich, S., Jogdand, P. S., Vestergaard, L. S., Dodoo, D., Højrup, P., Christiansen, M., Larsen, S. O., Singh, S. & Theisen, M., 1. Jan 2010, In : Malaria Journal. 9, p. 296

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Plasmodium falciparum
Malaria
Parasites
Molecular Weight
Nonparametric Statistics

Finding diabetic nephropathy biomarkers in the plasma peptidome by high-throughput magnetic bead processing and MALDI-TOF-MS analysis.

Hansen, HG., Overgaard, J., Lajer, M., Hubalek, F., Højrup, P., Pedersen, L., Tarnow, L., Rossing, P., Pociot, F. & McGuire, JN., Sep 2010, In : PROTEOMICS - Clinical Applications. 4, 8-9, p. 597-705

Research output: Contribution to journalJournal articleResearchpeer-review

Glycan profiling of proteins stored in the azurophilic granules of neutrophils

Ravnsborg, T., Houen, G. & Højrup, P., 27. Aug 2010.

Research output: Contribution to conference without publisher/journalPosterResearch

Glycanthrope: identifying glycan structures on peptides from a complex protein mixture

Rasmussen, M., Nielsen, J. CR. & Højrup, P., 27. Aug 2010.

Research output: Contribution to conference without publisher/journalPosterResearch

Synthesis and anti-angiogenic effect of conjugates between serum albumin and non-steroidal anti-inflammatory drugs

Kjær, B., Struve, C., Friis, T., Engel, A-M., Beyer, N. H., Højrup, P. & Houen, G., 1. Jan 2010, In : Protein and Peptide Letters. 17, 1, p. 121-130 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Serum Albumin
Anti-Inflammatory Agents
Naproxen
Pharmaceutical Preparations
Liver

The glycosylation and characterization of the candidate Gc macrophage activating factor

Ravnsborg, T., Olsen, D. T., Thysen, A. H., Christiansen, M., Houen, G. & Højrup, P., 13. Jan 2010, In : BBA General Subjects. 1804, 4, p. 909-917

Research output: Contribution to journalJournal articleResearchpeer-review

Vitamin D-Binding Protein
Glycosylation
Protein Isoforms
Galactosidases
Glycoside Hydrolases

The glycosylation of myeloperoxidase

Ravnsborg, T., Houen, G. & Højrup, P., 1. Oct 2010, In : BBA General Subjects. 1804, 10, p. 2046-53 8 p.

Research output: Contribution to journalJournal articleResearch

Glycosylation
Peroxidase
Epitope Mapping
Mannose
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Utilizing ion-pairing hydrophilic interaction chromatography solid phase extraction for efficient glycopeptide enrichment in glycoproteomics

Mysling, S., Palmisano, G., Højrup, P. & Thaysen-Andersen, M., 1. Jul 2010, In : Analytical Chemistry. 82, 13, p. 5598-609 12 p.

Research output: Contribution to journalJournal articleResearch

Glycopeptides
Chromatography
Ions
formic acid
Peptides
2009

Accurate and Site-specific Glycoprofiling using MALDI-MS: A Validation Study

Thaysen-Andersen, M., Mysling, S. & Højrup, P., 2009.

Research output: Contribution to conference without publisher/journalPosterResearch

A proteomics approach to study in vivo protein N(alpha)-modifications.

Zhang, X., Ye, J. & Højrup, P., 2009, In : Journal of Proteomics. 73, 2, p. 240-251 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI)

Valnickova, Z., Thaysen-Andersen, M., Højrup, P., Christensen, T., Sanggaard, K. W., Kristensen, T. & Enghild, J. J., 2009, In : BMC Biochemistry. 10, p. 13

Research output: Contribution to journalJournal articleResearchpeer-review

Carboxypeptidase B2
Plasmas
Fibrinolysis
Proteins
Glycosylation

CROSSWORK for Glycans: Glycan Identificatin Through Mass Spectrometry and Bioinformatics

Rasmussen, M., Thaysen-Andersen, M. & Højrup, P., 2009.

Research output: Contribution to conference without publisher/journalPosterResearch

Interaction of the chaperone calreticulin with proteins and peptides of different structural classes

Duus, K., Sandhu, N., Jørgensen, C. S., Hansen, P. R., Steinø, A., Thaysen-Andersen, M., Højrup, P. & Houen, G., 2009, In : Protein and Peptide Letters. 16, 11, p. 1414-1423 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Calreticulin
Ovalbumin
Peptides
Muramidase
Serum Albumin

Optimization of antibody immobilization for on-line or off-line immunoaffinity chromatography

Beyer, N. H., Schou, C., Højrup, P., Hansen, M. Z. & Heegaard, N. H. H., 26. May 2009, In : Journal of Separation Science. 32, 10, p. 1592-1604 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chromatography
Antibodies
Antigens
Proteins
Crosslinking

Peptide Mapping for Protein Characterization

Højrup, P., 2009, The Protein Protocols Handbook. Totowa: Humana Press

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Site-specific glycoprofiling of N-linked glycopeptides using MALDI-TOF MS: strong correlation between signal strength and glycoform quantities

Thaysen-Andersen, M., Mysling, S. & Højrup, P., 15. May 2009, In : Analytical Chemistry. 81, 10, p. 3933-3943 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glycopeptides
Ionization
Mass spectrometry
Polysaccharides
Desorption

Structure Determination of ER Proteins With Cross-linking, MS and Bioinformatics

Rasmussen, M., Ravnsborg, T., Houen, G., Larsen, H., Krogh, K., Nielsen, J. C. R., Rappsilber, J. & Rappsilber, J., 2009.

Research output: Contribution to conference without publisher/journalPosterResearch

The effects of possible contamination on the radiocarbon dating of the Dead Sea Scrolls II: Methods to remove castor oil

Rasmussen, K. L., van der Plicht, J., Doudna, G., Nielsen, F., Højrup, P., Stenby, E. H. & Pedersen, C. T., 2009, In : Radiocarbon: An International Journal of Cosmogenic Isotope Research. 3, p. 1005-1022 18 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Widespread abundance of functional bacterial amyloid in Mycolata and other Gram-positive bacteria

Jordal, P. B., Dueholm, M. S., Larsen, P., Petersen, S. V., Enghild, J. J., Christiansen, G., Højrup, P., Nielsen, P. H. & Otzen, D. E., 24. Apr 2009, In : Applied and Environmental Microbiology. p. 4101-4110

Research output: Contribution to journalJournal articleResearchpeer-review

amyloid
Gram-positive bacteria
bacterium
Gordonia amarae
spore
2008

Characterisation of the 1st SSI purified MBL standard

Laursen, I., Højrup, P., Houen, G. & Christiansen, M., 2008, In : Clinica Chimica Acta. 395, 1-2, p. 159-161 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Mannose-Binding Lectin
Salt removal
Mannose-Binding Protein-Associated Serine Proteases
Plasma (human)
Proteins

Identifying sources and estimating glandular output of salivary TIMP-1

Holten-Andersen, L., Beier Jensen, S., Bardow, A., Harslund, J., Thaysen-Andersen, M., Lademann, U., Autzen Usher, P., Offenberg, H., Højrup, P., Reibel, J., Nielsen, H. J., Brunner, N. & Nauntofte, B., 2008, In : Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 68, 7, p. 548-554 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Tissue Inhibitor of Metalloproteinase-1
Saliva
Mastication
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

Investigating the biomarker potential of glycoproteins using comparative glycoprofiling - application to tissue inhibitor of metalloproteinases-1

Thaysen-Andersen, M., Thøgersen, I. B., Lademann, U., Offenberg, H., Giessing, A., Enghild, J. J., Nielsen, H. J., Brünner, N. & Højrup, P., 1. Mar 2008, In : BBA General Subjects. 1784, 3, p. 455-463

Research output: Contribution to journalJournal articleResearchpeer-review

Tissue Inhibitor of Metalloproteinase-1
Colorectal Neoplasms
Colonic Neoplasms
Cell Line
Neoplasms

Molekylærbiologiske databaser

Højrup, P., 2008, Proteiner: Oprensning og karakterisering. Kielberg, V. & Rasmussen, L. (eds.). København: Gad, p. 171-184

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Small angle X-ray scattering study of calreticulin reveals conformational plasticity

Nørgaard Toft, K., Larsen, N., Steen Jørgensen, F., Højrup, P., Houen, G. & Vestergaard, B., 1. Sep 2008, In : BBA General Subjects. 1784, 9, p. 1265-1270 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Calreticulin
X-Rays
Calnexin
Placenta
Homeostasis

The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases

Pagh, R., Duus, K., Laursen, I., Hansen, P. R., Mangor, J., Thielens, N., Arlaud, G. J., Kongerslev, L., Højrup, P. & Houen, G., 1. Feb 2008, In : FEBS Journal. 275, 3, p. 515-26 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Mannose-Binding Protein-Associated Serine Proteases
Mitogen Receptors
Calreticulin
Salts
Complement C1q

The function of the human interferon-beta 1a glycan determined in vivo

Dissing-Olesen, L., Thaysen-Andersen, M., Meldgaard, M., Højrup, P. & Finsen, B., 1. Jul 2008, In : Journal of Pharmacology and Experimental Therapeutics. 326, 1, p. 338-47 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Congenic Mice
Relapsing-Remitting Multiple Sclerosis
Messenger RNA
Glycoside Hydrolases
Orthomyxoviridae
2007

An enzymatic deglycosylation scheme enabling identification of core fucosylated N-glycans and O-glycosylation site mapping of human plasma proteins

Hägglund, P., Matthiesen, R., Elortza, F., Højrup, P., Roepstorff, P., Jensen, O. N. & Bunkenborg, J., 1. Aug 2007, In : Journal of Proteome Research. 6, 8, p. 3021-3031 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glycosylation
Polysaccharides
Blood Proteins
Peptides
Glycoside Hydrolases

Calibration of matrix-assisted laser desorption/ionization time-of-flight peptide mass fingerprinting spectra

Hjernø, K. & Højrup, P., 2007, Methods in Molecular Biology: Mass Spectrometry Data Analysis in Proteomics. Matthiesen, R. (ed.). 1 ed. AAAI Press, Vol. 367. p. 49-60 11 p.

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Peptides

Determination of protein conformation by isotopically labelled cross-linking and dedicated software: Application to the chaperone, calreticulin

Nielsen, T., Andersen, M. T., Larsen, N., Jørgensen, F. S., Houen, G. & Højrup, P., 2007, In : International Journal of Mass Spectrometry. 268, 2-3, p. 217-226 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glycoprofiling of a biomarker for colorectal cancer

Andersen, M. T., Thøgersen, I. B., Nielsen, H. J., Lademann, U., Brünner, N. & Højrup, P., 2007.

Research output: Contribution to conference without publisher/journalPosterResearch