Peter Højrup

ph.d.

  • Campusvej 55

    5230 Odense M

    Denmark

1982 …2020
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Personal profile

Curriculum

Personal data:
Date & place of birth: 04-08-1953, Denmark
Address: Department of Biochemistry and Molecular Biology
University of Southern Denmark
Campusvej 55, DK-5230 Odense M
Contacts: php@bmb.sdu.dk; phone: +45 6550 2371

Academic degrees:
1986: PhD in Molecular Biology, Odense University
1982: MSc, Molecular Biology (major) and Chemistry (minor), The University of Aarhus

Employments:
2008-present: Professor MSO (Department of Biochemistry and Molecular Biology, University of Southern Denmark)
1991-2008: Associate Professor, (Department of Molecular Biology, Odense University, now University of Southern Denmark)
1989-1990: Postdoctoral fellow (Department of Molecular Biology, Odense University)
1988: Temporary Associate Professor (Dept. of Molecular Biology, Odense University)
1986-1988: Postdoctoral fellow (Department of Molecular Biology, Odense University)
1985-1986: Postdoctoral fellow (Department of Molecular Biology, Univ. of Aarhus)

Current research:
PHs research focuses on protein structure and function. A primary focus is the development of new methods for determining protein three-dimensional structure and protein interaction by chemical cross-linking followed by mass spectrometric determination of linkages. Another topic is the structure and function of the endoplasmatic proteins, in particular calreticulin and calnexin. Furthermore, development of methods for fast analysis of glycopeptides by mass spectrometry.

Specific topics
• Three-dimensional structure of calreticulin (mono, di- and multimers)
• Fast glycosylation analysis of immunoglobulins
• Glycopeptide quantitation
• Glycosylation analysis of cancer markers
• De novo proteomics of fish mucus proteins

Administrative experience:
2006-present: Ph.d. study leader, Faculty of Science, SDU

Editorial and reviewing tasks:
Editor for Journal of Proteomics.
Member of committees for appointments of assoc. and full Professorships in Denmark. Reviewer of grant proposals (Austria and Switzerland). Referee for a number of journals.

Supervision:
1 postdocs, 6 PhD students, 23 MSc students (4 Novo scholars; 1 Oticon) and 7 BSc students.

Congress organization:
Co-organizer of five conferences in Denmark on Mass spectrometry (2003-2006).

Fingerprint Dive into the research topics where Peter Højrup is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Proteins Medicine & Life Sciences
Peptides Medicine & Life Sciences
Calreticulin Medicine & Life Sciences
Mass spectrometry Chemical Compounds
Locusta migratoria Medicine & Life Sciences
Amino Acids Chemical Compounds
Glycosylation Medicine & Life Sciences
Diazepam Binding Inhibitor Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1982 2019

An IgY-based immunoassay to evaluate the biomarker potential of the Tannerella forsythia virulence factor karilysin in human saliva

Skottrup, P. D., López, R., Ksiazek, M., Højrup, P., Baelum, V., Potempa, J. & Kaczmarek, J. Z., Jun 2019, In : Journal of Immunological Methods. 469, p. 26-32

Research output: Contribution to journalJournal articleResearchpeer-review

Saliva
Immunoassay
Periodontitis
Point-of-Care Systems
Surface Plasmon Resonance
54 Downloads (Pure)

Enhanced trypsin on a budget: Stabilization, purification and high-temperature application of inexpensive commercial trypsin for proteomics applications

Heissel, S., Frederiksen, S. J., Bunkenborg, J. & Højrup, P., 27. Jun 2019, In : PLOS ONE. 14, 6, 16 p., e0218374.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
High temperature applications
proteomics
Trypsin
trypsin
Purification
69 Downloads (Pure)

Immunoglobulin G structure and rheumatoid factor epitopes

Maibom-Thomsen, S. L., Trier, N. H., Holm, B. E., Hansen, K. B., Rasmussen, M. I., Chailyan, A., Marcatili, P., Højrup, P. & Houen, G., 14. Jun 2019, In : PLOS ONE. 14, 6, 28 p., e0217624.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Rheumatoid Factor
immunoglobulin G
epitopes
Epitopes
Immunoglobulin G

Chaperone-client interactions between Hsp21 and client proteins monitored in solution by small angle X-ray scattering and captured by crosslinking mass spectrometry

Rutsdottir, G., I Rasmussen, M., Hojrup, P., Bernfur, K., Emanuelsson, C. & Söderberg, C. A. G., 2018, In : Proteins. 86, 1, p. 110-123

Research output: Contribution to journalJournal articleResearchpeer-review

X ray scattering
Crosslinking
Mass spectrometry
X-Rays
Small Heat-Shock Proteins
29 Downloads (Pure)

Discrimination of Isoleucine and Leucine by Dimethylation-Assisted MS3

Maibom-Thomsen, S., Heissel, S., Mørtz, E., Højrup, P. & Bunkenborg, J., 2018, In : Analytical Chemistry. 90, 15, p. 9055–9059

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Isoleucine
Leucine
Peptides
Ions
Thermolysin

Activities 2007 2013

Cross-linking human protein disulfide isomerase: what to do with a thousand cross-links?

Peter Højrup (Lecturer)
21. Nov 2013

Activity: Talks and presentationsTalks and presentations in private or public companies

MONOCLONAL PROTEINASE 3 ANTIBODIES BINDING AT THE ACTIVE SITE

Peter Højrup (Lecturer)
13. May 2012

Activity: Talks and presentationsTalks and presentations in private or public companies

Structure determination of human calreticulin by chemical cross-linking and mass spectrometry

Peter Højrup (Lecturer)
9. Dec 2011

Activity: Talks and presentationsTalks and presentations in private or public companies

Methods (Journal)

Peter Højrup (Peer reviewer)
21. Nov 2011

Activity: Editorial work and peer reviewPeer review of manuscriptsResearch

Projects 2001 2020

Press / Media

Respekt!

Peter Højrup

05/10/2018

1 Media contribution

Press/Media: Press / Media