Research output per year
Research output per year
MSc, PhD, DMSc
Design, analysis, and reporting of diagnostic and prognostic trials in molecular imaging.
----- Sequential and adaptive trial designs in diagnostic research -----
** Sample size recalculation based on the overall success rate in a randomized test- treatment trial with restricting randomization to discordant pairs. BMC Med Res Methodol. In press.
** A unified framework for diagnostic test development and evaluation during outbreaks of emerging infections. Commun Med (Lond). 2024; 4(1): 263. https://www.nature.com/articles/s43856-024-00691-9
** Sample size recalculation based on the prevalence in a randomized test-treatment study. BMC Med Res Methodol. 2022; 22(1): 205. https://doi.org/10.1186/s12874-022-01678-7
** Randomized test-treatment studies with an outlook on adaptive designs. BMC Med Res Methodol. 2021; 21(1): 110. https://doi.org/10.1186/s12874-021-01293-y
** The potential for seamless designs in diagnostic research. J Clin Epidemiol. 2021; 129: 51-59. https://doi.org/10.1016/j.jclinepi.2020.09.019
** Adaptive trial designs in diagnostic accuracy research. Stat Med. 2020; 39(5): 591-601. https://doi.org/10.1002/sim.8430
---- Other topics -----
** Modeling Bland–Altman Limits of Agreement with Fractional Polynomials – An Example with the Agatston Score for Coronary Calcification. Axioms. 2023; 12(9): 884. https://doi.org/10.3390/axioms12090884
** Convergence behavior of optimal cutpoints in receiver operating characteristics curve analysis. Mathematics 2022; 10(22): 4206. https://www.doi.org/10.3390/math10224206
** Nonparametric percentile curve estimation for a nonnegative marker with excessive zeros. MethodsX. 2022; 9: 101757. https://doi.org/10.1016/j.mex.2022.101757
** Bland-Altman Limits of Agreement from a Bayesian and frequentist perspective. Stats. 2021; 4(4): 1080-1090. https://doi.org/10.3390/stats4040062
** Reporting standards for a Bland-Altman agreement analysis: a review of methodological reviews. Diagnostics. 2020; 10(5): 334. https://doi.org/10.3390/diagnostics10050334
----- Recent clinical papers -----
** Diagnosing Bone Metastases in Breast Cancer: A Systematic Review and Network Meta-Analysis on Diagnostic Test Accuracy Studies of 2-[18F]FDG-PET/CT, 18F-NaF-PET/CT, MRI, Contrast-Enhanced CT, and Bone Scintigraphy. Semin Nucl Med. 2025; 55(1): 137-151. https://doi.org/10.1053/j.semnuclmed.2024.10.008
** Identifying the primary tumour in patients with cancer of unknown primary (CUP) using [18F]FDG PET/CT: a systematic review and individual patient data meta-analysis. Eur J Nucl Med Mol Imaging. 2024; 52(1): 225-236. https://doi.org/10.1007/s00259-024-06860-1
** Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock. N Engl J Med. 2024; 390(15): 1382-1393. https://doi.org/10.1056/NEJMoa2312572
Current position
Biostatistician, Department of Nuclear Medicine, Odense University Hospital & Professor in Clinical Biostatistics in Diagnostic Research, Dept. of Clinical Research, University of Southern Denmark
Former positions
2011-18 Associate Professor (20%), Dept. of Business and Economics, SDU
2006 Senior Statistician, Early Clinical Development, Novartis Pharma AG, Basel
2002-06 Biometrician, Clinical Statistics Europe, Schering AG, Berlin
2001/02 Junior Specialist, Information Resources GfK GmbH, Nürnberg
Higher education & academic degrees
2024 DMSc, Faculty of Health Sciences, University of Southern Denmark
2010 Lecturer Training Programme, University of Southern Denmark
2001 PhD, Department of Statistics and Econometrics, Faculty of Economics, University of Hamburg
1998 MSc in Mathematics and Economics, University of Hamburg
Membership of scientific societies
International Biometric Society (IBS)
International Society for Clinical Biostatistics (ISCB)
Danish Society for Theoretical Statistics (DSTS)
Co-supervision of ongoing PhD projects: 4
Main / co-supervision of completed PhD projects: 1 / 22
Main supervision of completed master theses: 10
Odense, 03 Jan 2025
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Gerke, O. (Participant)
Activity: Attending an event › Conference organisation or participation
Gerke, O. (Guest lecturer)
Activity: Talks and presentations › Talks and presentations in private or public companies
Gerke, O. (Guest lecturer)
Activity: Talks and presentations › Conference presentations
Gerke, O. (Participant)
Activity: Attending an event › Conference organisation or participation
Gerke, O. (Guest lecturer)
Activity: Talks and presentations › Talks and presentations in private or public companies
Madsen, S. (PhD student), Gjedde, A. (Supervisor), Brandt, L. (Supervisor), Videbech, P. (Supervisor), Gerke, O. (Supervisor) & Høilund-Carlsen, P. (Project applicant)
01/05/2018 → 01/05/2023
Project: PhD Project
Talal Elhakim, M., Stougaard, S. W., Gerke, O., Larsen, L. B., Graumann, O., Nielsen, M. & Rasmussen, B. S.
08/01/2024
1 item of Media coverage
Press/Media: Press / Media
13/12/2023
1 Media contribution
Press/Media: Press / Media
21/10/2019
1 Media contribution
Press/Media: Press / Media