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Personal profile

Curriculum

Current position

Biostatistician, Department of Nuclear Medicine, Odense University Hospital & Professor with specific responsibilities in clinical biostatistics in diagnostic research, Department of Clinical Research, University of Southern Denmark

Former positions

2011-18 Associate Professor (20%), Dep. of Business and Economics, SDU

2006 Senior Statistician, Early Clinical Development, Novartis Pharma AG, Basel

2002-06 Biometrician, Clinical Statistics Europe, Schering AG, Berlin

2001/02 Junior Specialist, Information Resources GfK GmbH, Nürnberg

Scientific focus area

Design, analysis, and reporting of diagnostic and prognostic trials in molecular imaging

---- Response evaluation -----

** Gerke O et al. PET/CT-based response evaluation in cancer – a systematic review of design issues. Mol Imaging Biol. In press. https://rdcu.be/byrOE (Author’s Accepted Manuscript: https://www.ogy.dk)

** Helland F et al. FDG-PET/CT versus contrast-enhanced CT for response evaluation in metastatic breast cancer: a systematic review. Diagnostics (Basel). 2019;9(3):106. https://www.ncbi.nlm.nih.gov/pubmed/31461923  

** Sjölander H et al. Value of FDG-PET/CT for treatment response in tuberculosis - a systematic review and meta-analysis. Clin Transl Imaging. 2018 Feb;6(1):19-29. http://rdcu.be/zsBK

** Vach W, Høilund-Carlsen PF, Fischer BM, Gerke O, Weber W. How to study optimal timing of PET/CT for monitoring of cancer treatment. Am J Nucl Med Mol Imaging. 2011;1(1):54-62. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477720

----- Sequential and adaptive trial designs in diagnostic research -----

** Gerke O et al. Group-sequential analysis may allow for early trial termination: illustration by an intra-observer repeatability study. EJNMMI Res. 2017;7:79.  http://rdcu.be/wd5R

----- Agreement -----

** Gerke O et al. Experience Applying the Guidelines for Reporting Reliability and Agreement Studies (GRRAS) Indicated Five Questions Should Be Addressed in the Planning Phase from a Statistical Point of View. Diagnostics (Basel). 2018;8(4):69. https://www.ncbi.nlm.nih.gov/pubmed/30249982

** Gerke O et al. How to assess intra- and inter-observer agreement with quantitative PET using variance component analysis: a proposal for standardization. BMC Med Imaging. 2016;16:54. http://rdcu.be/nhN5

Co-advisor of ongoing PhD projects: 4

Co-advisor of completed PhD projects: 16

Main supervision of completed master theses: 6

Teaching: BSc and MSc level

 

Odense, 13 Sep 2019

Fingerprint Dive into the research topics where Oke Gerke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

15 Downloads (Pure)
Open Access
File
Prostatic Neoplasms
Lymph Nodes
Radionuclide Imaging
Positron Emission Tomography Computed Tomography
Choline

A higher increase in FDG uptake in whole bone marrow of multiple myeloma patients from early to delayed pre-treatment scans is associated with poor response to treatment and inferior survival

Zadeh, M. Z., Østergaard, B., Raynor, W., Ayubcha, C., Acosta-Montenegro, O., Yellanki, D., Seraj, S. M., Rojulpote, C., Gerke, O., Constantinescu, C. M., Werner, T., Zhuang, H., Høilund-Carlsen, P. F. & Alavi, A., 1. May 2019, In : Journal of Nuclear Medicine. 60, Supplement 1, 21.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

A novel alignment procedure to assess calcified coronary plaques in histopathology, post-mortem computed tomography angiography and optical coherence tomography

Precht, H., Broersen, A., Kitslaar, P. H., Dijkstra, J., Gerke, O., Thygesen, J., Egstrup, K., Leth, P. M., Hardt-Madsen, M., Nielsen, B., Falk, E. & Lambrechtsen, J., Mar 2019, In : Cardiovascular Pathology. 39, p. 25-29

Research output: Contribution to journalReviewResearchpeer-review

Optical Coherence Tomography
Computed Tomography Angiography

Artificial intelligence-based versus manual assessment of prostate cancer in the prostate gland: a method comparison study

Mortensen, M. A., Borrelli, P., Poulsen, M. H., Gerke, O., Enqvist, O., Ulén, J., Trägårdh, E., Constantinescu, C., Edenbrandt, L., Lund, L. & Høilund-Carlsen, P. F., 22. Aug 2019, In : Clinical Physiology and Functional Imaging.

Research output: Contribution to journalJournal articleResearchpeer-review

Prostate
Prostatic Neoplasms
Neoplasm Grading
Weights and Measures
human glutamate carboxypeptidase II

Assessment of Physiological Intracranial Calcification in Healthy Adults Using 18F-NaF PET/CT.

Al-Zaghal, A., Seraj, S. M., Werner, T. J., Gerke, O., Høilund-Carlsen, P. F. & Alavi, A., Feb 2019, In : Journal of Nuclear Medicine. 60, 2, p. 267-271

Research output: Contribution to journalJournal articleResearchpeer-review

Choroid Plexus
Habenula
Pineal Gland
Retrospective Studies
Clinical Trials

Activities 2006 2019

IBS Summerschool on group-sequential and adaptive methods

Oke Gerke (Participant)
17 Oct 201919 Oct 2019

Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

File

Danish Society for Theoretical Statistics

Oke Gerke (Participant)
9 Apr 201910 Apr 2019

Activity: Attending an eventConference organisation or participation

File

Workshop on flexible designs for diagnostic studies

Oke Gerke (Participant)
1 Apr 20192 Apr 2019

Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

File

Response evaluation with PET/CT in cancer trials

Oke Gerke (Guest lecturer)
5 Feb 2019

Activity: Talks and presentationsConference presentations

File

Publiceringsstrategier i et forsker perspektiv

Oke Gerke (Guest lecturer)
30 Aug 2018

Activity: Talks and presentationsConference presentations

Press / Media

NAVNE I NOTER

Oke Gerke

10/10/2019

1 Media contribution

Press/Media: Press / Media

UDNÆVNT

Oke Gerke

07/10/2019

1 Media contribution

Press/Media: Press / Media

Oke Gerke er ansat som professor i klinisk biostatistik

Oke Gerke

02/10/2019

1 Media contribution

Press/Media: Press / Media

Professor i klinisk biostatistik

Oke Gerke

30/09/2019

1 Media contribution

Press/Media: Press / Media

Professor i klinisk biostatistik

Oke Gerke

30/09/2019

1 Media contribution

Press/Media: Press / Media