If you made any changes in Pure these will be visible here soon.

Research Output

2020

2D shear wave liver elastography by aixplorer to detect portal hypertension in cirrhosis: an individual patient data meta‐analysis

Thiele, M., Hugger, M. B., Kim, Y., Rautou, PE., Elkrief, L., Jansen, C., Verlinden, W., Allegretti, G., Israelsen, M., Stefanescu, H., Piscaglia, F., García‐Pagán, J. C., Franque, S., Berzigotti, A., Castera, L., Jeong, W. K., Trebicka, J. & Krag, A., 1. Jun 2020, In : Liver International. 40, 6, p. 1435-1446

Research output: Contribution to journalJournal articleResearchpeer-review

Cost-effectiveness of non-invasive screening for alcohol-related liver fibrosis

Galaxy Consortium, Jun 2020, In : Hepatology (Baltimore, Md.). 71, 6, p. 2093-2104

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Describing the fecal metabolome in cryogenically collected samples from healthy participants

Trošt, K., Ahonen, L., Suvitaival, T., Christiansen, N., Nielsen, T., Thiele, M., Jacobsen, S., Krag, A., Rossing, P., Hansen, T., Dragsted, L. O. & Legido-Quigley, C., 21. Jan 2020, In : Scientific Reports. 10, 8 p., 885.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
10 Downloads (Pure)

Mortality in biopsy-proven alcohol-related liver disease: A population-based nationwide cohort study of 3453 patients

Hagström, H., Thiele, M., Roelstraete, B., Söderling, J. & Ludvigsson, J. F., 1. Jan 2020, (Accepted/In press) In : GUT. 32220902.

Research output: Contribution to journalJournal articleResearchpeer-review

Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar-associated protein 4

Galaxy Consortium, Jul 2020, In : Liver International. 40, 7, p. 1701-1712

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Recent advances in alcohol-related liver disease (ALD): Summary of a Gut round table meeting

Avila, M. A., Dufour, J. F., Gerbes, A. L., Zoulim, F., Bataller, R., Burra, P., Cortez-Pinto, H., Gao, B., Gilmore, I., Mathurin, P., Moreno, C., Poznyak, V., Schnabl, B., Szabo, G., Thiele, M. & Thursz, M. R., Apr 2020, In : GUT. 69, 4, p. 764-780

Research output: Contribution to journalJournal articleResearchpeer-review

Skrumper en skrumpelever virkelig?

Thorhauge, K. & Thiele, M., 15. Feb 2020, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Steatosis Assessment with Controlled Attenuation Parameter (CAP) in Various Diseases.

Wernberg, C., Thiele, M. & Balle Hugger, M., 3. Jun 2020, Liver Elastography. Sebastian, M. (ed.). Springer, p. 441-457

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2019

2D-Shear-Wave elastography predicts survival in advanced chronic liver disease

Trebicka, J., De Ledinghen, V., Aube, C., Krag, A., Castera, L., Dumortier, J., Boursier, J., Friedrich-Rust, M., Stanislas, P., Grgurevic, I., Zheng, R., Francque, S., Gottfriedova, H., Sporea, I., Berzigotti, A., Wang, W., Rautou, P-E., Andrade, F., Strassburg, C. P., Zheng, J. & 16 others, Cassinotto, C., Wassil, M., Rasmussen, D., Vilgrain, V., Guibal, A., Vassord, C., Zeuzem, S., Vonghia, L., Senkerikova, R., Popescu, A., Paisant, A., Margini, C., Zuberbulher, F., Irles-Depe, M., Thiele, M. & Jansen, C., Apr 2019, In : Journal of Hepatology. 70, 1, Supple.1, p. E689

Research output: Contribution to journalConference abstract in journalResearchpeer-review

A Highly Accurate Panel Of Six Micrornas Predicts Early Fibrosis Progression In Patients With Alcohol-Related Liver Disease: A Biopsy-Controlled Study In 317 People

Thiele, M., Georgiou, S., Filippa, V., Madsen, B. S., Rasmussen, D., Kalavros, N., Delis, T., Moller, L., Jacobsen, S., Anastasiadou, E. & Krag, A., Oct 2019, In : Hepatology. 70, Suppl. 1, p. 171A 265.

Research output: Contribution to journalConference abstract in journalResearch

Clinical aspects of alcoholic liver disease

Bastrup Israelsen, M., Krag, A. & Thiele, M., 2019, The Human Gut-Liver-Axis in Health and Disease. Krag, A. & Hansen, T. (eds.). Springer, p. 3-21

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Combination of CCL4 with alcoholic and metabolic injuries mimics human liver fibrosis

Brol, M. J., Rösch, F., Schierwagen, R., Magdaleno, F., Uschner, F. E., Manekeller, S., Queck, A., Schwarzkopf, K., Odenthal, M., Drebber, U., Thiele, M., Lingohr, P., Plamper, A., Kristiansen, G., Lotersztajn, S., Krag, A., Klein, S., Rheinwalt, K. P. & Trebicka, J., 1. Aug 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 317, 2, p. G182-G194

Research output: Contribution to journalJournal articleResearchpeer-review

Different biomarkers reflecting different aspects of fibrogenesis holds a potential to improve diagnostics of alcohol liver disease: serological deconstruction of fibrosis, ballooning and inflammation.

Villesen, I., Gudmann, N., Thiele, M., Nielsen, M. J., Leeming, D. J., Karsdal, M. & Krag, A., Oct 2019, In : Hepatology. 70, Suppl. 1, p. 824A 1357.

Research output: Contribution to journalConference abstract in journalResearch

En million danskere har fedtlever. Her er 5 gode råd til at undgå bekymring og store undersøgelser

Gluud, L. L., Fialla, A. D. & Thiele, M., 14. Oct 2019, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

High levels of basement membrane remodelling (C4M) and low activity of wound healing (FPA) reflect fibrosis in alcoholic liver disease

Gudmann, N., Thiele, M., Nielsen, M. J., Madsen, B. S., Detlefsen, S., Moeller, L. S., Kjaergaard, M., Leeming, D., Karsdal, M. & Krag, A., Apr 2019, In : Journal of Hepatology. 70, 1 Suppl.1, p. E817

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Hvordan finder vi ud af, om fedtlever er uskadelig?

Gluud, L. L., Dam Fialla, A. & Thiele, M., Oct 2019, In : Ugeskrift for Laeger. 2019, 20

Research output: Contribution to journalComment/debateCommunication

Hvorfor skader alkohol leveren?

Johansen, S. & Thiele, M., 21. Nov 2019, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Open Access

Impact Of Binge Drinking On Hepatic Lipid Metabolism: Lipidome Analysis Of Liver Vein And Peripheral Blood During Acute Alcohol Intoxication

Israelsen, M., Trost, K., Madsen, B. S., Suvitaival, T. R., Hansen, C. D., Thiele, M., Rossing, P., Hensen, T., Legido-Quigley, C., Krag, A. & Consortium, M., Oct 2019, In : Hepatology. 70, Suppl. 1, p. 172A-173A 267.

Research output: Contribution to journalConference abstract in journalResearch

Serial testing with the enhanced liver fibrosis test and liver stiffness is cost-effective for detection of advanced alcoholic liver disease in primary care

Thiele, M., Asphaug, L., Krag, A. & Melberg, H. O., Apr 2019, In : Journal of Hepatology. 70, 1, suppl. 1, p. E345-E346

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Spleen stiffness to liver stiffness ratio significantly differs between ALD and HCV and predicts disease-specific complications

Elshaarawy, O., Mueller, J., Guha, I. N., Chalmers, J., Harris, R., Krag, A., Stæhr Madsen, B., Stefanescu, H., Farcau, O., Ardelean, A., Procopet, B., Thiele, M. & Mueller, S., Aug 2019, In : JHEP Reports. 1, 2, p. 99-106

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
71 Downloads (Pure)

Spleen to liver stiffness ratio significantly differs between ALD and HCV and predicts disease specific complications

Elshaarawy, O., Mueller, J., Guha, I. N., Chalmers, J., Harris, R., Thiele, M., Madsen, B. S., Krag, A., Stefanescu, H., Stancu, O., Ardelean, A. & Mueller, S., 1. Apr 2019, In : Journal of Hepatology. 70, 1 suppl. 1, p. E640

Research output: Contribution to journalConference abstract in journalResearchpeer-review

The Pro-Peptide Of Type Vi Collagen (Endotrophin) Is Equipotent To Tgf-B In Inducing Fibrosis: Identification Of A Self-Perpetuating Vicious Cycle Driving Fibrosis Mediated By Collagen Signals

Karsdal, M., Reese-Petersen, A., Nielsen, M. J., Krag, A., Thiele, M., Gudmann, N. & Genovese, F., Oct 2019, In : Hepatology. 70, Suppl. 1, p. 84A-85A 128.

Research output: Contribution to journalConference abstract in journalResearch

Trænger din lever til en måned uden fedt og alkohol?

Lindvig, K. P. & Thiele, M., 12. Jan 2019, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Transient elastography for screening of liver fibrosis: Cost-effectiveness analysis from six prospective cohorts in Europe and Asia

Serra-Burriel, M., Graupera, I., Torán, P., Thiele, M., Roulot, D., Wai-Sun Wong, V., Neil Guha, I., Fabrellas, N., Arslanow, A., Expósito, C., Hernández, R., Lai-Hung Wong, G., Harman, D., Darwish Murad, S., Krag, A., Pera, G., Angeli, P., Galle, P., Aithal, G. P., Caballeria, L. & 4 others, Castera, L., Ginès, P., Lammert, F. & investigators of the LiverScreen Consortium, 1. Dec 2019, In : Journal of Hepatology. 71, 6, p. 1141-1151

Research output: Contribution to journalJournal articleResearchpeer-review

2018

Accuracy of the Enhanced Liver Fibrosis Test vs Fibrotest, Elastography and Indirect Markers in Detection of Advanced Fibrosis in Patients with Alcoholic Liver Disease

Thiele, M., Madsen, B. S., Hansen, J. F., Detlefsen, S., Antonsen, S. & Krag, A., Apr 2018, In : Gastroenterology. 154, 5, p. 1369-1379

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
189 Downloads (Pure)

Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: Study protocol for a randomized controlled trial

Madsen, B. S., Trebicka, J., Thiele, M., Israelsen, M., Arumugan, M., Havelund, T. & Krag, A., 26. Feb 2018, In : Trials. 19, 5 p., 143.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
214 Downloads (Pure)

Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data based meta-analysis

Herrmann, E., de Lédinghen, V., Cassinotto, C., Chu, W. C-W., Leung, V. Y-F., Ferraioli, G., Filice, C., Castera, L., Vilgrain, V., Ronot, M., Dumortier, J., Guibal, A., Pol, S., Trebicka, J., Jansen, C., Strassburg, C. P., Zheng, R., Zheng, J., Francque, S., Vanwolleghem, T. & 11 others, Vonghia, L., Manesis, E. K., Zoumpoulis, P., Sporea, I., Thiele, M., Krag, A., Cohen-Bacrie, C., Criton, A., Gay, J., Deffieux, T. & Friedrich-Rust, M., Jan 2018, In : Hepatology. 67, 1, p. 260–272

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
168 Downloads (Pure)

Controlled Attenuation Parameter And Alcoholic Hepatic Steatosis: Diagnostic Accuracy and Role Of Alcohol Detoxification

Thiele, M., Rausch, V., Fluhr, G., Kjærgaard, M., Piecha, F., Mueller, J., Straub, B. K., Lupşor-Platon, M., De-Ledinghen, V., Seitz, H. K., Detlefsen, S., Madsen, B., Krag, A. & Mueller, S., May 2018, In : Journal of Hepatology. 68, 5, p. 1025-1032

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
254 Downloads (Pure)

Controlled attenuation parameter er en ny metode til screening for ikkealkoholisk fedtleversygdom

Translated title of the contribution: Controlled attenuation parameter is a novel technique in screening for non-alcoholic fatty liver diseaseSøholm, J., Thiele, M. S. & Christensen, P. B., 29. Jan 2018, In : Ugeskrift for Laeger. 180, 17, p. 2-5 V05170414.

Research output: Contribution to journalJournal articleResearchpeer-review

Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis

Nguyen-Khac, E., Thiele, M., Voican, C., Nahon, P., Moreno, C., Boursier, J., Mueller, S., de Ledinghen, V., Stärkel, P., Gyune Kim, S., Fernandez, M., Madsen, B., Naveau, S., Krag, A., Perlemuter, G., Ziol, M., Chatelain, D. & Diouf, M., 1. Sep 2018, In : The Lancet Gastroenterology and Hepatology. 3, 9, p. 614-625

Research output: Contribution to journalJournal articleResearchpeer-review

Non-Invasive Markers Are Superior to Histological Fibrosis Stage for Predicting LiverRelated Outcomes in Alcoholic Liver Disease

Rasmussen, D., Thiele, M., Madsen, B. S., Moller, L., Antonsen, S., Detlevsen, S. & Krag, A., Oct 2018, In : Hepatology. 68, suppl. 1, p. 780A 1 p.

Research output: Contribution to journalConference abstract in journalResearch

Sådan påvirker decembers flæsk, sovs og snaps din fordøjelse

Thiele, M., 9. Dec 2018, In : Videnskab.dk.

Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

2017

Contemporary use of elastography in liver fibrosis and portal hypertension

Thiele, M., Kjærgaard, M., Thielsen, P. & Krag, A., 2017, In : Clinical Physiology and Functional Imaging. 37, 3, p. 235–242

Research output: Contribution to journalReviewResearchpeer-review

Controlled Attenuation Parameter (CAP) for the assessment of alcoholic hepatic steatosis: biopsy-controlled diagnostic accuracy and role of detoxification

Thiele, M., Rausch, V., Fluhr, G., Piecha, F., Mueller, J., Straub, B., Stæhr Madsen, B., Detlefsen, S. & Krag, A., 1. Sep 2017. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Long Version)

Dietrich, C. F., Bamber, J., Berzigotti, A., Bota, S., Cantisani, V., Castera, L., Cosgrove, D., Ferraioli, G., Friedrich-Rust, M., Gilja, O. H., Goertz, R. S., Karlas, T., de Knegt, R., de Lédinghen, V., Piscaglia, F., Procopet, B., Saftoiu, A., Sidhu, P. S., Sporea, I. & Thiele, M., 1. Aug 2017, In : Ultraschall in der Medizin (Stuttgart, Germany : 1980). 38, 4, p. e16-e47

Research output: Contribution to journalJournal articleResearch

EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Short Version)

Dietrich, C. F., Bamber, J., Berzigotti, A., Bota, S., Cantisani, V., Castera, L., Cosgrove, D., Ferraioli, G., Friedrich-Rust, M., Gilja, O. H., Goertz, R. S., Karlas, T., de Knegt, R., de Lédinghen, V., Piscaglia, F., Procopet, B., Saftoiu, A., Sidhu, P. S., Sporea, I. & Thiele, M., 1. Aug 2017, In : Ultraschall in der Medizin (Stuttgart, Germany : 1980). 38, 4, p. 377-394

Research output: Contribution to journalJournal articleResearch

Erratum: EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Long Version)

Dietrich, C. F., Bamber, J., Berzigotti, A., Bota, S., Cantisani, V., Castera, L., Cosgrove, D., Ferraioli, G., Friedrich-Rust, M., Gilja, O. H., Goertz, R. S., Karlas, T., de Knegt, R., de Ledinghen, V., Piscaglia, F., Procopet, B., Saftoiu, A., Sidhu, P. S., Sporea, I. & Thiele, M., Aug 2017, In : Ultraschall in der Medizin (Stuttgart, Germany : 1980). 38, 4, p. e48

Research output: Contribution to journalComment/debateResearchpeer-review

High risk of misinterpreting liver and spleen stiffness using 2D shear-wave and transient elastography after a moderate or high calorie meal

Kjærgaard, M., Thiele, M., Jansen, C., Stæhr Madsen, B., Görtzen, J., Strassburg, C. P., Trebicka, J. & Krag, A., 2017, In : PLOS ONE. 12, 4, 15 p., e0173992.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
223 Downloads (Pure)

Human ascites microfibril associeret protein 4 (MFAP4) er en uafhængig prædikter for død ved dekompenseret cirrose

Translated title of the contribution: Human ascites microfibrilassociated protein 4 (MFAP4) is an independent predictor of mortality in decompensated cirrhosisStæhr Madsen, B., Kjærgaard, M., Thiele, M., Pohlmann, A., Lutz, P., Schierwagen, R., Klein, S., Jansen, C., Lehmann, J., Mortensen, C., Wilkens Knudsen, A., Trebicka, J., Schlosser, A., Holmskov, U., Sørensen, G. L. & Krag, A., 1. Sep 2017. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Hvad laver en lever?

Thiele, M., 11. Oct 2017, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Impact of metabolic risk factors in non-cirrhotic patients with alcoholic liver disease

Thiele, M., 22. Oct 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Is liver stiffness equal to liver fibrosis?

Thiele, M., Madsen, B. S. & Krag, A., 1. Feb 2017, In : Hepatology. 65, 2, p. 749 1 p.

Research output: Contribution to journalComment/debateResearch

Pharmacological interventions for alcoholic liver disease (alcohol-related liver disease): an attempted network meta-analysis

Buzzetti, E., Kalafateli, M., Thorburn, D., Davidson, B. R., Thiele, M., Gluud, L. L., Del Giovane, C., Askgaard, G., Krag, A., Tsochatzis, E. & Gurusamy, K. S., 2017, In : Cochrane Database of Systematic Reviews. 2017, 3, 182 p., CD011646.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
216 Downloads (Pure)

Prediction of presence of oesophageal varices just by shear-wave elastography of the liver and spleen

Jansen, C., Thiele, M., Verlinden, W., Krag, A., Francque, S. & Trebicka, J., Sep 2017, In : Liver International. 37, 9, p. 1406-1407

Research output: Contribution to journalComment/debateResearch

Quality of life and pituitary function in patients with hereditary hemochromatosis: An observational study

Dahl, E., Haaber, A., Kimer, N., Thiele, M., Bach, J. & Gluud, L. L., 2017, In : Journal of Gastroenterology and Hepatology Research. 2, 1, 6 p., 006.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
189 Downloads (Pure)

Reliability Criteria for Liver Stiffness Measurements with Real-Time 2D Shear Wave Elastography in Different Clinical Scenarios of Chronic Liver Disease

Thiele, M., Stæhr Madsen, B., Procopet, B., Fuglsang Hansen, J., Møller, L. M. S., Detlefsen, S., Berzigotti, A. & Krag, A., 2017, In : Ultraschall in der Medizin. 38, 6, p. 648-654

Research output: Contribution to journalJournal articleResearchpeer-review