Research output per year
Research output per year
- 20 results
Search results
-
2023
Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness
Chandran, V. I., Wernberg, C. W., Lauridsen, M. M., Skytthe, M. K., Bendixen, S. M., Larsen, F. T., Hansen, C. D., Grønkjær, L. L., Siersbæk, M. S., Caterino, T. D., Detlefsen, S., Møller, H. J., Grøntved, L., Ravnskjaer, K., Moestrup, S. K., Thiele, M. S., Krag, A. & Graversen, J. H., Feb 2023, In: Hepatology. 77, 2, p. 558-572Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Downloads (Pure) -
Stellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity
Larsen, F. T., Hansen, D., Terkelsen, M. K., Bendixen, S. M., Avolio, F., Wernberg, C. W., Lauridsen, M. M., Grønkjaer, L. L., Jacobsen, B. G., Klinggaard, E. G., Mandrup, S., Di Caterino, T., Siersbæk, M. S., Chandran, V. I., Graversen, J. H., Krag, A., Grøntved, L. & Ravnskjaer, K., Feb 2023, In: JHEP Reports. 5, 2, 100615.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile17 Downloads (Pure) -
2022
Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells
Weis-Banke, S. E., Lisle, T. L., Perez-Penco, M., Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Marie Svane, I., Met, Ö., Ødum, N., Madsen, D. H., Donia, M., Grøntved, L. & Andersen, M. H., Oct 2022, In: Journal for immunotherapy of cancer. 10, 10, e005326.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Downloads (Pure) -
TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
Perez-Penco, M., Weis-Banke, S. E., Schina, A., Siersbæk, M., Hübbe, M. L., Jørgensen, M. A., Lecoq, I., Lara De La Torre, L., Bendtsen, S. K., Martinenaite, E., Holmström, M. O., Madsen, D. H., Donia, M., Ødum, N., Grøntved, L. & Andersen, M. H., 6. Dec 2022, In: Journal for immunotherapy of cancer. 10, 12, e005491.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Downloads (Pure) -
2021
Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage
Præstholm, S. M., Correia, C. M., Goitea, V. E., Siersbæk, M. S., Jørgensen, M., Havelund, J. F., Pedersen, T. Å., Færgeman, N. J. & Grøntved, L., 2. Nov 2021, In: Cell Reports. 37, 5, 109938.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile54 Downloads (Pure) -
2020
C57BL/6J substrain differences in response to high-fat diet intervention
Siersbæk, M. S., Ditzel, N., Hejbøl, E. K., Præstholm, S. M., Markussen, L. K., Avolio, F., Li, L., Lehtonen, L., Hansen, A. K., Schrøder, H. D., Krych, L., Mandrup, S., Langhorn, L., Bollen, P. & Grøntved, L., 1. Dec 2020, In: Scientific Reports. 10, 15 p., 14052.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile51 Downloads (Pure) -
Collagen Density Modulates the Immunosuppressive Functions of Macrophages
Larsen, A. M. H., Kuczek, D. E., Kalvisa, A., Siersbæk, M. S., Thorseth, M. L., Johansen, A. Z., Carretta, M., Grøntved, L., Vang, O. & Madsen, D. H., 1. Sept 2020, In: Journal of immunology (Baltimore, Md. : 1950). 205, 5, p. 1461-1472Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone
Præstholm, S. M., Siersbæk, M. S., Nielsen, R., Zhu, X., Hollenberg, A. N., Cheng, S-Y. & Grøntved, L., 2020, In: PLOS Genetics. 16, 5, 26 p., e1008770.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile71 Downloads (Pure) -
Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial
Godskesen, L. E., Lassen, T. R., Jespersen, N. R., Siersbæk, M., Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G., Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J., 12. Jun 2020, In: Scientific Reports. 10, 15 p., 9537.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile111 Downloads (Pure) -
2019
Collagen density regulates the activity of tumor-infiltrating T cells
Kuczek, D. E., Larsen, A. M. H., Thorseth, M-L., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, L. H., Noessner, E., Donia, M., Svane, I. M., Straten, P. T., Grøntved, L. & Madsen, D. H., 12. Mar 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, 15 p., 68.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile138 Downloads (Pure) -
2018
Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver
Kalvisa, A., Siersbæk, M. S., Præstholm, S. M., Christensen, L. J. L., Nielsen, R., Stohr, O., Vettorazzi, S., Tuckermann, J., White, M., Mandrup, S. & Grøntved, L., 10. Dec 2018, In: PLOS Biology. 16, 12, p. 1-32 e2006249.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile210 Downloads (Pure) -
2017
High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss
Siersbæk, M., Varticovski, L., Yang, S., Baek, S., Nielsen, R., Mandrup, S., Hager, G., H. Chung, J. & Grøntved, L., 10. Jan 2017, In: Scientific Reports. 7, 13 p., 40220.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile234 Downloads (Pure) -
Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo
Hönes, G. S., Rakov, H., Logan, J., Liao, X. H., Werbenko, E., Pollard, A. S., Præstholm, S. M., Siersbæk, M. S., Rijntjes, E., Gassen, J., Latteyer, S., Engels, K., Strucksberg, K. H., Kleinbongard, P., Zwanziger, D., Rozman, J., Gailus-Durner, V., Fuchs, H., De Angelis, M. H., Klein-Hitpass, L., & 8 others, 2017, In: Proceedings of the National Academy of Sciences (PNAS). 114, 52, p. E11323-E11332Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake
Madsen, D. H., Jürgensen, H. J., Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, N., Grøntved, L., Weigert, R. & Bugge, T. H., 26. Dec 2017, In: Cell Reports. 21, 13, p. 3662-3671Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile168 Downloads (Pure) -
2016
MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3
Hallenborg, P., Siersbæk, M., Barrio-Hernandez, I., Nielsen, R., Kristiansen, K., Mandrup, S., Grøntved, L. & Blagoev, B., 1. Jul 2016, In: Cell Death & Disease. 7, 6, p. e2289Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile135 Downloads (Pure) -
2015
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers
Loft, A., Forss, I., Siersbæk, M. S., Schmidt, S. F., Larsen, A-S. B., Madsen, J. G. S., Pisani, D. F., Nielsen, R., Aagaard, M. M., Mathison, A., Neville, M. J., Urrutia, R., Karpe, F., Amri, E-Z. & Mandrup, S., 2015, In: Genes & Development. 29, 1, p. 7-22Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile326 Downloads (Pure) -
Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling.
Jafari, A., Siersbæk, M., Chen, L., Qanie, D. W. M., Zaher, W., Abdallah, B. & Kassem, M., Jul 2015, In: Stem Cells. 33, 7, p. 2219–2231Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
2012
Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression
Siersbæk, M., Loft, A., Jørgensen, M. M. A., Nielsen, R., Schmidt, S. F., Petrovic, N., Nedergaard, J. & Mandrup, S., 2012, In: Molecular and Cellular Biology. 32, 17, p. 3452-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PPARs: fatty acid sensors controlling metabolism
Poulsen, L. L. C., Siersbæk, M. & Mandrup, S., 2012, In: Seminars in Cell and Developmental Biology. 23, 6, p. 631-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2010
A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes
Bugge, A., Siersbæk, M., Madsen, M. S., Göndör, A., Rougier, C. & Mandrup, S., 4. Jun 2010, In: Journal of Biological Chemistry. 285, 23, p. 17310-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review