Moustapha Kassem

  • J.B. Winsløws Vej 25, 1.

    5000 Odense C


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Personal profile


Title: professor, Dr. Moustapha Kassem


November 1983                 MBBCh., Kasr-Al-Aini Medical School, University of Cairo, Egypt.

March 1985                        Egyptian medical license.

January 1988                      Danish medical license.

July 1993                           License to practice medicine in USA and UK

August 1994                       PhD in Medicine, University of Aarhus, Aarhus, Denmark

November 1997                 Doctorate of Science (DSc), University of Aarhus, Aarhus, Denmark.



1995                                   The young investigator award, American Society for Bone and Mineral Research

1996                                   Award for best research project, the Danish Society of Internal Medicine 

2003                                         Generalkonsul Ernst Carlsens foundation award

2004                                                              Research prize from the Danish Free Masons Society.

2008                                                               Queen Ingrid’s Lecture, Åbenrå Hospital.

2010                                  Prize for outstanding scientific communication, University of

                                          Southern Denmark, Denmark

2012                                  Marie & August Krogh award, Danish Medical Association.

2012                                  Award for outstanding scientific achievement, Faculty of Health Sciences, University of Southern Denmark.

2015                                  SEB-Codan award, Danish Medical Association.

2020                                  Louis Avioli Founder Award, the American Society for Bone and Mineral Research



May 2002                           Chief Physician, Department of Endocrinology, Diabetes and Metabolism, University Hospital of Odense, Odense, Denmark

May 2002                           Professor of Molecular Endocrinology, University of Southern Denmark, Odense, Denmark and director for Laboratory of Molecular Endocrinology, Medical Biotechnology Center.

2013                                   Professor of Stem Cell Biology, Danish National Stem Cell Center (Danstem), Faculty of Health Sciences, University of Copenhagen



Dec 89-Dec 92                   PhD student, Osteoporosis Research Unit, Aarhus University Hospital, Aarhus, Denmark.

Aug 93-July 95                  Postdoctoral Fellow, Department of Endocrinology and Metabolism, Mayo Clinic, Rochester, Minnesota, USA.

July 2012- July 2013          Visiting professor, Center of System Biology, Faculty of Science, University of New South Wales, Sydney, Australia.

February-March 2017        Visiting professor, The Garvan Institute for medical research, Sydney, Austrlia.




Scientific Director of Stem Cell Treatment Centre, University Hospital of Odense, Odense, Denmark.


Principal investigator of the Indo-Danish Initiative of Stem Cells and Nanotechnology which is collaboration between Universities of Southern Denmark, University of Aarhus and Stem Cell Centre at Bangalore and Kerala, India,


Regular reviewer for Nature Medicine, Nature Biotechnology, Journal of bone and Mineral Research, Bone, European Journal of Clinical Investigation, Endocrinology, European Journal of Endocrinology, International Journal of Developmental Biology, Calcified Tissue International, Stem Cells, Tissue Engineering, European Journal of Hematology, Biogerontology, Osteoporosis International.


Reviewed grants for Medical Research councils in Norway, UK, Austria, Singapore, China, Finland and France. Reviewed PhD thesis (15) and Dr.Med (doctorate degree of Medical Sciences) thesis (2). Evaluation of professorships (8).


Lecturing frequently at national and international meetings. In 2015 and 2020 more than 100 presentations at national and international meetings with plenary lectures, symposia presentation, meet the professor sessions in major stem cell and endocrinology conferences including Annual meeting of Endocrine Society, Annual meetings of American Society for Bone and Mineral Research, European Calcified Tissue Society and Annual meetings of European Society of Endocrinology.


Editorship and Board Membership:

Member of editorial board of Biogerontolog (1999- 2004)

Member of editorial board of Clinical Endocrinology (2007-)

Member of editorial board of Stem Cell Reviews (2008-)

Associate editor Aging Cell (2016-)

Editor Bone (2012-)

Editor Stem Cell Research (2015-2017)

Stem Cell Research and Therapy (2014-)

Member of the Scientific-Ethical Committee of Aarhus County (1999-2001).

Board member of the Danish Society for Endocrinology (2002-2007)

Board member of the Danish Bone and Tooth Society (2000-2004)

Board Member of the Centre for Art and Science, University of Southern Denmark (2004- )

Board member of PhD graduate school of Stem Cell Research and PhD graduate school of Metabolic diseases.

Board Member of Nordic Research Foundation, Novo Nordisk Foundation (2004-2014)

Member of the advisory board of International Osteoporosis Foundation (IOF) (2009-2014)

Member of Nordic Council on Bioethics (2012-2014)

American Society for Bone and Mineral Research Ethics Advisory Committee (2014- )



PhD students 30, post-doctoral scientists 21, Master students 16, Medical Students (research year) 10, bachelor students 3.



1. PCT/EP2012/060997 miRNA-138 for use in regulation of osteoblast differentiation of


2.  PCT/EP2013/059207 Identification of a novel molecule (chemical) to enhance bone cell differentiation of skeletal (mesenchymal) stem cells

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Research Output

Delta-like 1 (DLK1) is a possible mediator of vitamin D effects on bone and energy metabolism

Bassatne, A., Jafari, A., Kassem, M., Mantzoros, C., Rahme, M. & El-Hajj Fuleihan, G., Sep 2020, In : Bone. 138, 115510.

Research output: Contribution to journalJournal articleResearchpeer-review

  • Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism

    Weivoda, M. M., Chew, C. K., Monroe, D. G., Farr, J. N., Atkinson, E. J., Geske, J. R., Eckhardt, B., Thicke, B., Ruan, M., Tweed, A. J., McCready, L. K., Rizza, R. A., Matveyenko, A., Kassem, M., Andersen, T. L., Vella, A., Drake, M. T., Clarke, B. L., Oursler, M. J. & Khosla, S., 7. Jan 2020, In : Nature Communications. 11, 13 p., 87.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
  • 54 Downloads (Pure)

    Identification of osteolineage cell-derived extracellular vesicle cargo implicated in hematopoietic support

    Morhayim, J., Ghebes, C. A., Erkeland, S. J., ter Borg, M. N. D., Hoogenboezem, R. M., Bindels, E. M. J., van Alphen, F. P. J., Kassem, M., van Wijnen, A. J., Cornelissen, J. J., van Leeuwen, J. P., van der Eerden, B. C. J., Voermans, C., van de Peppel, J. & Braakman, E., 1. Apr 2020, In : FASEB Journal. 34, 4, p. 5435-5452

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
  • 34 Downloads (Pure)

    Less is more: Corroborating a genomic biomarker identifying human bone marrow multipotent stromal cells with high scalability

    Burns, J. S. & Kassem, M., 20. Aug 2020, In : Stem Cells.

    Research output: Contribution to journalJournal articleCommunication

    MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway

    Vishnubalaji, R., Elango, R., Manikandan, M., Siyal, A. A., Ali, D., Al-Rikabi, A., Hamam, D., Hamam, R., Benabdelkamel, H., Masood, A., Alanazi, I. O., Alfadda, A. A., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 1. Dec 2020, In : Cell Death Discovery. 6, 16 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
  • 8 Downloads (Pure)


    Danish Bone Research Workshop

    Justyna Kowal (Participant), , Li Chen (Participant), , Michaela Tencerova (Participant), , Nicholas Ditzel (Participant), , Abbas Jafari (Participant), & Moustapha Kassem (Participant)

    2. Feb 20184. Feb 2018

    Activity: Attending an eventConference organisation or participation

    Pathophysiology of osteoporotic bone loss

    Moustapha Kassem (Lecturer)

    22. Oct 2017

    Activity: Talks and presentationsGuest lectures, external teaching and course activities at other universities

    Bone Morphology in IKBKG (NEMO) Mutation Positive Women. A case-control study

    Morten Frost (Guest lecturer), , Michaela Tencerova (Guest lecturer), , Charlotte Albjerg Ejersted (Guest lecturer), , Dea Svaneby (Guest lecturer), , Christina Møller Andreasen (Guest lecturer), , Thomas Levin Andersen (Guest lecturer), , Moustapha Kassem (Guest lecturer), , William H McAlister (Guest lecturer), , D. Novack (Guest lecturer), , Michael P Whyte (Guest lecturer), & Anja Lisbeth Frederiksen (Guest lecturer)

    9. Sep 2017

    Activity: Talks and presentationsConference presentations

    Third International Meeting on Bone Marrow Adiposity

    Moustapha Kassem (Participant), & Michaela Tencerova (Participant)

    31. Aug 20171. Sep 2017

    Activity: Attending an eventConference organisation or participation

    Press / Media


    Moustapha Kassem


    1 Media contribution

    Press/Media: Press / Media


    Honorary award from Danish Doctors Association sponsored by Codan and SEB Pensions

    Kassem, Moustapha (Recipient), 5. Feb 2015

    Prize: Prizes, scholarships, distinctions

    Forskningsformidlingsprisen 2010: Syddansk Universitet

    Kassem, Moustapha (Recipient), 1. Oct 2010

    Prize: Prizes, scholarships, distinctions

    Generalkonsul Ernst Carlsens Fonds pris

    Kassem, Moustapha (Recipient), 2003

    Prize: Prizes, scholarships, distinctions