Personal profile

Research interests

I am a cancer researcher with a specific interest in cancer prevention and prediction. My work  focuses on cancer aetiology, through studying effects of environmental and genetics factors on 
cancer risk and progression. I use range of approaches in my work, from observational  epidemiological studies of risk factors, including case-control, population-based cohort studies,  twin studies, to meta-analysis and umbrella reviews, and multi-omics data analysis to study associations between environmental exposures, genetics, and intermediate phenotypes (biomarkers). The overarching aim of my work is to improve cancer prediction by understanding risk factors of cancer, improving cancer screening, and thus improving survival 
of cancer patient and cancer outcomes. My work is characterized by collaborative and international nature as reflected in my publication list.

Research areas

  • Understanding genetics of cancer risk through multi-omic analysis.
  • Interdisciplinary Project on Adherance to Colorectal Cancer Screening. A short description of the project can be found here.
  • Meta-analysis and systematic literature review of factors associated with false-positive and false-negative FOBT results. The details of the study protocol and methods are published in PROSPERO (ID: CRD42022315767).
  • COlorectal Cancer screening Among RElatives (CoCARE): a twin-family study in Denmark.

Education/Academic qualification

Epidemiology, Dr.sc.hum, Investigations into the role of Glutathione-S-transferase (GST) and Cytochrome-P450-monooxygenase (CYP) polymorphisms as risk factors for early onset lung cancer, Heidelberg University

20052009

Award Date: 19. Feb 2009

External positions

Honorary Fellow, The University of Edinburgh

7. Dec 2019 → …

Statistical Geneticist , The University of Edinburgh

20132019

Postdoctoral Fellow, International Agency for Research on Cancer

20092013

Research areas

  • Cancer
  • genetic and environmental risk factors
  • molecular epidemiology
  • Bioinformatics
  • Genome Analysis
  • Genetics
  • RNA
  • DNA
  • Prevention and Screening

Fingerprint

Dive into the research topics where Maria Timofeeva is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Researchers

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Circulating 25-hydroxyvitamin D and survival outcomes of colorectal cancer: evidence from population-based prospective cohorts and Mendelian randomisation

    Zhang, X., He, Y., Li, X., Shraim, R., Xu, W., Wang, L., Farrington, S. M., Campbell, H., Timofeeva, M., Zgaga, L., Vaughan-Shaw, P., Theodoratou, E. & Dunlop, M. G., 13. Mar 2024, (E-pub ahead of print) In: British Journal of Cancer.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
  • Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

    Thomas, M., Su, Y. R., Rosenthal, E. A., Sakoda, L. C., Schmit, S. L., Timofeeva, M. N., Chen, Z., Fernandez-Rozadilla, C., Law, P. J., Murphy, N., Carreras-Torres, R., Diez-Obrero, V., van Duijnhoven, F. J. B., Jiang, S., Shin, A., Wolk, A., Phipps, A. I., Burnett-Hartman, A., Gsur, A., Chan, A. T., & 108 othersZauber, A. G., Wu, A. H., Lindblom, A., Um, C. Y., Tangen, C. M., Gignoux, C., Newton, C., Haiman, C. A., Qu, C., Bishop, D. T., Buchanan, D. D., Crosslin, D. R., Conti, D. V., Kim, D. H., Hauser, E., Siegel, E., Schumacher, F. R., Rennert, G., Giles, G. G., Hampel, H., Brenner, H., Oze, I., Oh, J. H., Lee, J. K., Schneider, J. L., Chang-Claude, J., Kim, J., Huyghe, J. R., Zheng, J., Hampe, J., Greenson, J., Hopper, J. L., Palmer, J. R., Visvanathan, K., Matsuo, K., Matsuda, K., Jung, K. J., Li, L., Le Marchand, L., Vodickova, L., Bujanda, L., Gunter, M. J., Matejcic, M., Jenkins, M. A., Slattery, M. L., D’Amato, M., Wang, M., Hoffmeister, M., Woods, M. O., Kim, M., Song, M., Iwasaki, M., Du, M., Udaltsova, N., Sawada, N., Vodicka, P., Campbell, P. T., Newcomb, P. A., Cai, Q., Pearlman, R., Pai, R. K., Schoen, R. E., Steinfelder, R. S., Haile, R. W., Vandenputtelaar, R., Prentice, R. L., Küry, S., Castellví-Bel, S., Tsugane, S., Berndt, S. I., Lee, S. C., Brezina, S., Weinstein, S. J., Chanock, S. J., Jee, S. H., Kweon, S. S., Vadaparampil, S., Harrison, T. A., Yamaji, T., Keku, T. O., Vymetalkova, V., Arndt, V., Jia, W. H., Shu, X. O., Lin, Y., Ahn, Y. O., Stadler, Z. K., Van Guelpen, B., Ulrich, C. M., Platz, E. A., Potter, J. D., Li, C. I., Meester, R., Moreno, V., Figueiredo, J. C., Casey, G., Lansdorp Vogelaar, I., Dunlop, M. G., Gruber, S. B., Hayes, R. B., Pharoah, P. D. P., Houlston, R. S., Jarvik, G. P., Tomlinson, I. P., Zheng, W., Corley, D. A., Peters, U. & Hsu, L., 2. Oct 2023, In: Nature Communications. 14, 13 p., 6147.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
    7 Downloads (Pure)
  • Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

    Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z., Law, P., Thomas, M., Schmit, S., Díez-Obrero, V., Hsu, L., Fernandez-Tajes, J., Palles, C., Sherwood, K., Briggs, S., Svinti, V., Donnelly, K., Farrington, S., Blackmur, J., Vaughan-Shaw, P., Shu, X. O., Long, J., Cai, Q., & 190 othersGuo, X., Lu, Y., Broderick, P., Studd, J., Huyghe, J., Harrison, T., Conti, D., Dampier, C., Devall, M., Schumacher, F., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Moratalla-Navarro, F., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J., Jenkins, M., Win, A. K., Pai, R., Figueiredo, J., Haile, R., Gallinger, S., Woods, M., Newcomb, P., Duggan, D., Cheadle, J., Kaplan, R., Maughan, T., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, L. P., Jousilahti, P., Knekt, P., Aaltonen, L., Rissanen, H., Pukkala, E., Eriksson, J., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Zanke, B., Männistö, S., Albanes, D., Weinstein, S., Ruiz-Narvaez, E., Palmer, J., Buchanan, D., Platz, E., Visvanathan, K., Ulrich, C., Siegel, E., Brezina, S., Gsur, A., Campbell, P., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M., Potter, J., Tsilidis, K., Schulze, M., Gunter, M., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Stern, M., Pardamean, B., Bishop, T., Giles, G., Southey, M., Idos, G., McDonnell, K., Abu-Ful, Z., Greenson, J., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T., van Guelpen, B., Hudson, T., Hampel, H., Pearlman, R., Berndt, S., Hayes, R., Martinez, M. E., Thomas, S., Corley, D., Pharoah, P., Larsson, S., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K., Pugh, E., Shelford, T., Chan, A., Cruz-Correa, M., Lindblom, A., Hunter, D., Joshi, A., Schafmayer, C., Scacheri, P., Kundaje, A., Nickerson, D., Schoen, R., Hampe, J., Stadler, Z., Vodicka, P., Vodickova, L., Vymetalkova, V., Papadopoulos, N., Edlund, C., Gauderman, W., Thomas, D., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S., van Duijnhoven, F., Feskens, E., Sakoda, L., Gago-Dominguez, M., Wolk, A., Naccarati, A., Pardini, B., FitzGerald, L., Lee, S. C., Ogino, S., Bien, S., Kooperberg, C., Li, C., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Tangen, C., Mardis, E., Yamaji, T., Sawada, N., Iwasaki, M., Haiman, C., Le Marchand, L., Wu, A., Qu, C., McNeil, C., Coetzee, G., Hayward, C., Deary, I., Harris, S., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Moreno, V., Casey, G., Gruber, S., Tomlinson, I., Zheng, W., Dunlop, M., Houlston, R. & Peters, U., Jan 2023, In: Nature Genetics. 55, p. 89-99

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
    60 Downloads (Pure)
  • Development and Validation of Risk Prediction Models for Colorectal Cancer in Patients with Symptoms

    Xu, W., Mesa-Eguiagaray, I., Kirkpatrick, T., Devlin, J., Brogan, S., Turner, P., Macdonald, C., Thornton, M., Zhang, X., He, Y., Li, X., Timofeeva, M., Farrington, S., Din, F., Dunlop, M. & Theodoratou, E., Jul 2023, In: Journal of Personalized Medicine. 13, 7, 16 p., 1065.

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
    19 Downloads (Pure)
  • Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk

    Zhou, X., Xiao, Q., Jiang, F., Sun, J., Wang, L., Yu, L., Zhou, Y., Zhao, J., Zhang, H., Yuan, S., Timofeeva, M., Spiliopoulou, A., Mesa-Eguiagaray, I., Farrington, S. M., Law, P. J., Houlston, R. S., Ding, K., Dunlop, M. G., Theodoratou, E. & Li, X., Oct 2023, In: British Journal of Cancer. 129, 8, p. 1306-1313

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
    File
    3 Downloads (Pure)