Kent Søe

Search results

• 2023

  How to support implementation of the ambitious strategy “to actively involve patients and relatives in all parts of the research process” at Odense University Hospital

  Lykke Jensen, J., Janssens, A., Kragh-Sørensen, A., Friis Olsen, A., Nielsen, D. S., Kidholm, K., Søe, K., Lærkner, E. A., Karlsson, A. T., Hinnerup Hartmeyer, L. & Agerskov, H., 25. Apr 2023.

  Research output: Contribution to conference without publisher/journal › Poster › Communication
• 2022

  Bone resorptive activity of human osteoclasts is altered on bone from Osteogenesis Imperfecta patients and mouse models in vitro

  Folkestad, L., Fritzen, M. E., Tauer, J., Olesen, J. B., Winther, V., Duran, I., Komarova, S., Nijhuis, W., Kruse, R., Rogers, K., Sakkers, R., Delaissé, J.-M. & Søe, K., 8. May 2022.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Human osteoclasts in vitro are both inhibited and stimulated dose dependently by cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC)

  Nielsen, S. S., Pedersen, J., Sharma, N., Wasehuus, P., Marie Julie Møller, A., Søndergaard, T. E. & Søe, K., 8. May 2022.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Reduced sensitivity to zoledronic acid of human osteoclasts from smokers in vitro parallels their blood cells' DNA methylation

  Tan, Q., Marie Julie Møller, A., Madsen, J. S., Bechmann, T., Delaissé, J.-M., Kristensen, B. W., Karasik, D. & Søe, K., 9. May 2022.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2020

  Human osteoclasts generated from different individuals show a highly variable sensitivity to zoledronic acid in vitro – osteoclasts from smokers are less sensitive!

  Marie Julie Møller, A., Delaissé, J.-M., Bechmann, T., Olesen, J. B., Madsen, J. S., Canto, L. M. D., Hugger Jakobsen, E., Rogatto, S. R. & Søe, K., 31. Jan 2020.

  Research output: Contribution to conference without publisher/journal › Poster › Research
• 2019

  BoneBio: Breast cancer and bone biomarkers: Poster to abstract #24 BoneBio: The variable sensitivity of breast cancer patients to zoledronic acid

  Marie Julie Møller, A., Bechmann, T., Madsen, J. S., Hugger Jakobsen, E. & Søe, K., 29. Aug 2019, p. 38. 1 p.

  Research output: Contribution to conference without publisher/journal › Poster › Research

  Open Access

  • Biological Marker 100%
  • Breast Cancer 100%
  • Zoledronic Acid 100%
  • Clinical Research 100%
  • Cytotechnology 75%

• BoneProst: Prostate cancer and bone biomarkers

  Poulsen, M. H., Osther, P. J. S., Marie Volmer, L., Madsen, J. S., Nørby, B., Lund, L., Mejlholm, I. & Søe, K., 29. Aug 2019.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

  • Scintigraphy 100%
  • Quality of Life 100%
  • Bone Resorption 100%
  • Polyethylene Terephthalate 100%
  • Acid Treatment 100%
• 2018

  Human osteoclasts generated from different individuals show a highly variable sensitivity to zoledronic acid in vitro - this sensitivity relates to in vivo characteristics of each individual

  Marie Julie Møller, A., Delaissé, J.-M., Bechmann, T., Madsen, J. S., Marie Volmer, L. & Søe, K., 3. Jul 2018.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Mild inhibition of CatK paradoxically stimulates the resorptive activity of osteoclasts co-cultured with osteoblast lineage cells

  Pirapaharan, D. C., Søe, K., Panwar, P., Christensen, S. B., Kjærsgaard-Andersen, P., Madsen, J. S., Brömme, D. & Delaissé, J.-M., 27. May 2018.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2017

  SEPT9 is involved in osteoclast bone resorption

  Marie Julie Møller, A., Füchtbauer, E.-M., Brüel , A., Levin Andersen, T., Borggaard, X. G., S Thomsen, J., S Pedersen, F., Delaissé, J.-M. & Søe, K., 2017.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• The variable sensitivity to treatment against bone resorption

  Marie Julie Møller, A., Delaissé, J.-M., Skov Madsen, J. & Søe, K., 2017.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Unraveling the molecular determinants of continuous long-term bone resorption by osteoclasts

  Borggaard, X. G., Pirapaharan, D. C., Marie Julie Møller, A., Delaissé, J.-M. & Søe, K., 2017.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2016

  Comparison of the Anti-Resorptive Activities of an Ectosteric With an Active Site Inhibitor of Cathepsin K.

  Panwar, P., Søe, K., Delaissé, J.-M. & Bromme, D., 2016.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Control of bone resorption by the rate of osteoprogenitor recruitment during bone remodeling

  Lassen, N. E., Levin Andersen, T., Søe, K., Hauge, E. M., Harving, S., Eser Toft Eschen, G. & Delaissé, J.-M., 2016.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Septin 9 – a critical player in osteoclast resorption.

  Julie Marie Møller, A., Delaissé, J.-M., Füchtbauer, E.-M. & Søe, K., 2016.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Slow and Fast Bone Resorption Modes of Human Osteoclasts Revealed by Time-lapse Recording.

  Søe, K. & Delaissé, J.-M., 2016.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2015

  Ectosteric inhibitors of cathepsin K prevent bone resorption

  Panwar, P., Søe, K., Law, S., Delaissé, J.-M. & Brömme, D., 11. Oct 2015.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Pit And Trench Forming Osteoclasts: a Distinction That Matters?

  Merrild, D. M. H., Pirapaharan, D. C., Andreasen, C. M., Kjærsgaard-Andersen, P., Ding, M., Delaissé, J.-M. & Søe, K., 12. Oct 2015.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2014

  A novel approach to inhibit bone resorption: Ectosite inhibitors against cathepsin K

  Panwar, P., Søe, K., Cui, H., Du, X., Delaissé, J.-M. & Bromme, D., 2014.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• The elementary fusion modalities of osteoclasts

  Søe, K., Hobolt-Pedersen, A.-S. & Delaissé, J.-M., 2014.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2013

  OC Fusion: Regulation through Collagen and Mineral Contacts at the Marrow/Bone Interface? The American Society for Bone and Mineral Research, Annual Meeting 2013

  Søe, K., Levin Andersen, T. & Delaissé, J.-M., 4. Oct 2013.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2012

  "Differences and similarities in treatment related effects of zoledronic acid in multiple myeloma and breast cancer patients with metastasis to bone." in Journal of Bone and Mineral Research, 27, suppl.1, p213-S214.

  Søe, K., Delaissé, J.-M., Hugger Jakobsen, E., Hansen, C. & Plesner, T., 2012. 2 p.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• "Distinct Roles of cathepsin K and MMPs in Osteoclastic Bone Resorption" in Journal of Bone and Mineral research, 27, suppl. 1, p283-284

  Merrild, D. M. H., Søe, K. & Delaissé, J.-M., 2012. 2 p.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Does collagen trigger migration of reversal cells into vacated bone resorption lacunae? i Journal of Bone and Mineral Research, 27, suppl. 1, p.172

  Abdelgawad, M. E., Søe, K., Engelholm, L. H., Kjærsgaard-Andersen, P., Behrendt, N. & Delaissé, J.-M., 2012. 1 p.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• "Is zoledronic acid retention onto bone different in multiple myeloma and breast cancer patients with bone metastasis?" in Journal of Bone and Mineral Research, 27, suppl. 1, p323

  Søe, K., Plesner, T., Hugger Jakobsen, E., Hansen, C., Jørgensen, H. & Delaissé, J.-M., 2012. 1 p.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2010

  An in vivo assessment of the relation between critical shortening of telomeres and osteoarthritis in humans: Telomeres and the DNA Damage Response. EMBO

  Harbo, M., Bendix, L., Jensen, A.-C. B., Graakjær, J., Søe, K., Levin Andersen, T., Kjærsgaard-Andersen, P., Delaissé, J.-M. & Kølvraa, S., 14. Sept 2010.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2009

  Bone remodeling compartments are critical in cushing

  Jensen, P. R., Levin Andersen, T., Søe, K., Hauge, E., Bollerslev, J. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Clucocorticoids alter the osteoclast resorption mode

  Søe, K. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Glucocorticoids act directly on osteoclasts, and maitain them in the active mode of the resorption cycle: an explanation for immediate bone fragilization after glucocorticoid treatment

  Søe, K. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Rapid stimulation of bone formation by Bortezomib in multiple myeloma

  Lund, T., Søe, K., Abildgaard, N., Garnero, P., Pedersen, P., Delaissé, J.-M. & Plesner, T., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Syncytin1 is involved in osteoclast fusion

  Søe, K., Bjerregaard, B., Hobolt-Pedersen, A.-S., Larsson, L.-I. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Syncytin 1 is involved in osteoclast fusion

  Søe, K., Bjerregaard, B., Larsson, L.-I. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• The molecular mechanism behind osteoclast-mmyeloma cell fusion

  Hobolt-Pedersen, A.-S., Søe, K., Kupisiewicz, K. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• The proteasome inhibitor bortezomib overcomes the inhibition of osteoblast function observed in multiple myeloma

  Lund, T., Søe, K., Abildgaard, N., Garnero, P., Pedersen, P., Ormstrup, T., Delaissé, J.-M. & Plesner, T., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Uncooupling of Bone resoption and bone formation correlates with disruption of the bone remodeling compartment: A study in cushings patients

  Jensen, P. R., Levin Andersen, T., Søe, K., Hauge, E., Bollerslev, J. & Delaissé, J.-M., 2009.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
• 2008

  Biological prerequisites for heterotypic fusion between myeloma cells and osteoclasts

  Kupisiewicz, K., Søe, K., Levin Andersen, T., Søndergaard, T. E., Plesner, T. & Delaissé, J.-M., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Chondrocyte telomere length decreases as the level of cartilage degeneration in human osteoathritic knees increases

  Harbo, M., Graakjær, J., Bendix, L., Jensen, A.-C. B., Søe, K., Delaissé, J.-M. & Kølvraa, S., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Myeloma cell-induced collapse of the vascular bone remodeling compartments leads to osteolysis and the generation of osteoclast-myeloma hybrid cells

  Levin Andersen, T., Søe, K., Søndergaard, T. E., Kupisiewicz, K., Plesner, T. & Delaissé, J.-M., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research

• Proteasome Inhibition Counteracts the Negative Effect of Glucocorticoid Treatment on Bone Metabolism by Stimulating Osteoblasts and Inhibiting Osteoclasts in Vitro

  Søe, K., Levin Andersen, T., Lund, T., Plesner, T. & Delaissé, J.-M., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Proteasome inhibition enhances anti-myeloma and anti-osteoclastic effects of glucocorticoids and weakens the anti-osteoblastic effects

  Søe, K., Levin Andersen, T., Plesner, T. & Delaissé, J.-M., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Proteasome inhibition protects osteoblasts from glucocorticoid-induced damage and enhances glucocorticoid-induced toxicity against osteoclasts

  Søe, K., Levin Andersen, T., Plesner, T. & Delaissé, J.-M., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review

• Resveratrol analogs as potential treatment of multiple myeloma and bone related disease: Effect on myeloma cells and osteoclasts in vitro

  Kupisiewicz, K., Boissy, P., Søe, K., Plesner, T. & Delaissé, J.-M., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research

• The bone degradation marker CTX shows unique properties in disease monitoring compared to NTX, ICTP and bALP in multiple myeloma

  Lund, T., Delaissé, J.-M., Abildgaard, N., Kupisiewicz, K., Levin Andersen, T., Søe, K. & Plesner, T., 2008.

  Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review