Personal profile
Research Interests
I am a Mandrup group post-doc on the ATLAS project since September 2020. My interest lies in investigating adipose tissue plasticity during obesity development and regression. I will specifically be looking at ectopic adipose depots and its impact on peripheral tissue metabolism, during regression of obesity. With this research focus, we hope to aid in better understanding of clinical obesity and its relapse in humans.
Education/Academic qualification
Molecular Physiology, PhD, Investigating oscillatory epigenomic mechanisms that mediate metabolic transitions, Tata Institute of Fundamental Research
1. Aug 2014 → 28. Jan 2020
Award Date: 28. Jan 2020
Biotechnology, B.Tech, National Institute of Technology- Calicut
1. Sept 2010 → 30. Apr 2014
Award Date: 30. Apr 2014
Chromatin & Gene expression, Short term Post-doc, Tata Institute of Fundamental Research
1. Feb 2020 → 31. Jul 2020
Keywords
- Metabolism
- Regulation of gene expression
- Obesity and associated diseases
- Regulatory RNA
- Transcriptional Control
Fingerprint
- 1 Similar Researchers
Collaborations and top research areas from the last five years
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Single-cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss
Loft, A., Rydbirk, R., Klinggaard, E. G., Hauwaert, E. L. V., Wernberg, C. W., Møller, A. F., Dam, T. V., Hassan, M. N., Maniyadath, B., Nielsen, R., Krag, A., Kalucka, J., Schmidt, S. F., Lauridsen, M. E. M., Madsen, J. G. S. & Mandrup, S., Jan 2026, In: Nature Metabolism. 8, 1, p. 260-278Research output: Contribution to journal › Journal article › Research › peer-review
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Adipose tissue cell states linked to progression and clinical subtypes of MASLD in human obesity
Madsen, J. D., Dam, T. V., Nambiar, J., Liang, C., Peltonen, A. R., Wernberg, C. W., Rydbirk, R., Oussoren, L. M. K., Jakobsen, K. S., Gammelmark Klinggaard, E., Hansen, D., Maniyadath, B., Jonasson, E., Caterino, T. D., Krag, A., Ravnskjær, K., Mandrup, S., Lauridsen, M., Loft, A. & Schmidt, S. F., 29. Sept 2025, In: BioRxiv.Research output: Contribution to journal › Journal article › Research
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Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss
Loft, A., Rydbirk, R., Gammelmark Klinggaard, E., van Hauwaert, E. L., Wernberg, C. W., Møller, A. F., Dam, T. V., Hassan, M. N., Maniyadath, B., Nielsen, R., Krag, A., Kalucka, J., Schmidt, S. F., Lauridsen, M., Madsen, J. G. S. & Mandrup, S., 31. Jan 2025, In: BioRxiv.Research output: Contribution to journal › Journal article › Research
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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution
Loft, A., Emont, M. P., Weinstock, A., Divoux, A., Ghosh, A., Wagner, A., Hertzel, A. V., Maniyadath, B., Deplancke, B., Liu, B., Scheele, C., Lumeng, C., Ding, C., Ma, C., Wolfrum, C., Strieder-Barboza, C., Li, C., Truong, D. D., Bernlohr, D. A. & Stener-Victorin, E. & 46 others, , 2025, In: Nature Metabolism. 7, 5, p. 875-894Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Adipose tissue at single-cell resolution
Maniyadath, B., Zhang, Q., Gupta, R. K. & Mandrup, S., 7. Mar 2023, In: Cell Metabolism. 35, 3, p. 386-413Research output: Contribution to journal › Journal article › Research › peer-review
Open Access
Projects
- 1 Finished
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EMBO - Uncovering molecular mechanisms of in-vivo adipogenesis using single cell transcriptomics
Maniyadath, B. (Project participant)
01/09/2021 → 31/08/2024
Project: Research