Jane Stubbe

Search results

• 2020

  Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice

  Ellman, D. G., Lund, M. C., Nissen, M., Nielsen, P. S., Sørensen, C., Lester, E. B., Pedersen, E. T., Jørgensen, L. H., Nedospasov, S., Andersen, D. C., Stubbe, J., Brambilla, R., Degn, M. & Lambertsen, K. L., 3. Nov 2020, In: Cells. 9, 11, 23 p., 2407.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Spinal Cord Injuries
  • Myeloid Cells
  • Chemokine CXCL1
  • Neutrophils
  • Receptors, Tumor Necrosis Factor, Type I
  16 Downloads (Pure)

• Intraluminal infusion of Penta-Galloyl Glucose reduces abdominal aortic aneurysm development in the elastase rat model

  Schack, A. S., Stubbe, J., Steffensen, L. B., Mahmoud, H., Laursen, M. S. & Lindholt, J. S., 28. Aug 2020, In: PLOS ONE. 15, 8, 14 p., e0234409.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Rubiaceae
  • Pancreatic Elastase
  • Abdominal Aortic Aneurysm
  • Glucose
  • Messenger RNA
  34 Downloads (Pure)
• 2019

  Effect of spironolactone for 1 yr on endothelial function and vascular inflammation biomarkers in renal transplant recipients

  Mortensen, L. A., Bistrup, C., Stubbe, J., Carlström, M., Checa, A., Wheelock, C. E., Palarasah, Y., Bladbjerg, E. M., Thiesson, H. C. & Jensen, B. L., 1. Sep 2019, In: American Journal of Physiology: Renal Physiology. 317, 3, p. F529-F539

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Spironolactone
  • Transplant Recipients
  • Biomarkers
  • Inflammation
  • Blood Vessels
  13 Downloads (Pure)

• Nephrotic syndrome is associated with increased plasma K ⁺ concentration, intestinal K ⁺ losses, and attenuated urinary K ⁺ excretion: a study in rats and humans

  Ydegaard, R., Svenningsen, P., Bistrup, C., Andersen, R. F., Stubbe, J., Buhl, K. B., Marcussen, N., Hinrichs, G. R., Iraqi, H., Zamani, R., Dimke, H. & Jensen, B. L., 1. Dec 2019, In: American Journal of Physiology: Renal Physiology. 317, 6, p. F1549-F1562

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Nephrotic Syndrome
  • Epithelial Sodium Channels
  • Puromycin Aminonucleoside
  • Kidney
  • Mineralocorticoid Receptors
  15 Downloads (Pure)

• TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex

  Yli-Karjanmaa, M. L. K., Larsen, K. S., Fenger, C., Kristensen, L. K., Martin, N. A., jensen, P. T., Breton, A., Nathanson, L., Nielsen, P. V., Lund, M. C., Lindeman Carlsen, S., Gramsbergen, J. B., Finsen, B., Stubbe, J., Frich, L. H., Stolp, H., Brambilla, R., anthony, D., Meyer, M. & Lambertsen, K. L., 1. Nov 2019, In: Brain, Behavior, and Immunity. 82, p. 279-297

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Cerebral Cortex
  • Neurons
  • Etanercept
  • Cell Count
  • Inhibition (Psychology)
  158 Downloads (Pure)
• 2018

  Abdominal Aortic Aneurysms Growth Is Associated With High Concentrations of Plasma Proteins in the Intraluminal Thrombus and Diseased Arterial Tissue

  Behr-Rasmussen, C., Lindholt, J. S., Urbonavicius, S., Halekoh, U., Jensen, P. S., Stubbe, J., Rasmussen, L. M. & Beck, H. C., Sep 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 9, p. 2254–2267

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Abdominal Aortic Aneurysm
  • Blood Proteins
  • Thrombosis
  • Growth
  • Porosity

• Experimental comparative study of thrombogenicity of two differently luminal heparinized ePTFE vascular prosthetics

  Liisberg, M., Stenger, M., Behr-Rasmussen, C., Stubbe, J. & Lindholt, J. S., 1. Nov 2018, In: Annals of Medicine and Surgery. 35, p. 76-81

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Polytetrafluoroethylene
  • Transplants
  • Blood Vessels
  • Heparin
  • Sheep
  182 Downloads (Pure)

• Identification of differential gene expression patterns in human arteries from patients with chronic kidney disease

  Stubbe, J., Skov, V., Thiesson, H. C., Larsen, K. E., Hansen, M. L., Jensen, B. L., Jespersen, B. & Rasmussen, L. M., 1. Jun 2018, In: American Journal of Physiology: Renal Physiology. 314, 6, p. F1117-F1128

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Chronic Renal Insufficiency
  • Arteries
  • Gene Expression
  • Messenger RNA
  • Genes
  182 Downloads (Pure)
• 2017

  Induction of autoimmune abdominal aortic aneurysm in pigs: A novel large animal model

  Riber, S. S., Ali, M., Bergseth, S. H., Stubbe, J., Stenger, M., Behr-Rasmussen, C. & Lindholt, J. S., Aug 2017, In: Annals of Medicine and Surgery. 20, p. 26-31

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Abdominal Aortic Aneurysm
  • Swine
  • Animal Models
  • Heterografts
  • Sheep
  276 Downloads (Pure)

• P/Q-type and T-type voltage-gated calcium channels are involved in the contraction of mammary and brain blood vessels from hypertensive patients

  Thuesen, A. D., Lyngsø, K. S., Rasmussen, L., Stubbe, J., Skøtt, O., Rom Poulsen, F., Pedersen, C. B., Rasmussen, L. M. & Hansen, P. B. L., 1. Mar 2017, In: Acta Physiologica. 219, 3, p. 642–653

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Calcium Channels
  • Breast
  • Blood Vessels
  • Brain
  • Arterioles

• The water channel AQP1 is expressed in human atherosclerotic vascular lesions and AQP1 deficiency augments angiotensin II-induced atherosclerosis in mice

  Wintmo, P., Johansen, S. H., Hansen, P. B. L., Lindholt, J. S., Urbonavicius, S., Rasmussen, L. M., Bie, P., Jensen, B. L. & Stubbe, J., Aug 2017, In: Acta Physiologica. 220, 4, p. 446–460

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Aquaporins
  • Angiotensin II
  • Atherosclerosis
  • Blood Vessels
  • Apolipoproteins E
• 2016

  Animal Models Used to Explore Abdominal Aortic Aneurysms: A Systematic Review

  Lysgaard Poulsen, J., Stubbe, J. & Lindholt, J. S., 16. Aug 2016, In: European Journal of Vascular and Endovascular Surgery. 52, 4, p. 487-499

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Abdominal Aortic Aneurysm
  • Systematic Reviews
  • Animal Models
  • Aortic Diseases
  • Pancreatic Elastase

• MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation

  Schlosser, A., Pilecki, B., Hemstra, L. E., Kejling, K., Kristmannsdottir, G. B., Wulf-Johansson, H., Moeller, J. B., Füchtbauer, E-M., Nielsen, O., Kirketerp-Møller, K., Dubey, L. K., Hansen, P. B. L., Stubbe, J., Wrede, C., Hegermann, J., Ochs, M., Rathkolb, B., Schrewe, A., Bekeredjian, R., Wolf, E. & 6 others, Gailus-Durner, V., Fuchs, H., de Angelis, M. H., Lindholt, J. S., Holmskov, U. & Sorensen, G. L., Jan 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 1, p. 122-133

  Research output: Contribution to journal › Journal article › Research › peer-review

  • microfibrillar protein
  • Neointima
  • Vascular Smooth Muscle
  • Integrins
  • Smooth Muscle Myocytes
• 2014

  Prostaglandin I₂ and Prostaglandin E₂ Modulate Human Intrarenal Artery Contractility Through Prostaglandin E2-EP4, Prostacyclin-IP, and Thromboxane A2-TP Receptors

  Eskildsen, M. P., Hansen, P. B. L., Stubbe, J., Walter, S., Marcussen, N., Rasmussen, L. M., Vanhoutte, P. M. & Jensen, B. L., Sep 2014, In: Hypertension. 64, 3, p. 551-556

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prostaglandin H2 Receptors Thromboxane A2
  • Thromboxane Receptors
  • Epoprostenol
  • Dinoprostone
  • Arteries

• Salt sensitivity of renin secretion, glomerular filtration rate and blood pressure in conscious Sprague-Dawley rats

  Isaksson, G. L., Stubbe, J., Hansen, P. L., Jensen, B. L. & Bie, P., Feb 2014, In: Acta Physiologica (Print). 210, 2, p. 446–454

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Renin
  • Glomerular Filtration Rate
  • Sprague Dawley Rats
  • Blood Pressure
  • Metoprolol

• The water channel aquaporin-1 contributes to renin cell recruitment during chronic stimulation of renin production

  Tinning, A. R., Jensen, B. L., Schweda, F., Machura, K., Hansen, P. B. L., Stubbe, J., Gramsbergen, J. B. & Madsen, K., 1. Dec 2014, In: American Journal of Physiology: Renal Physiology. 307, 11, p. F1215-F1226

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Aquaporins
  • Renin
  • Angiotensin-Converting Enzyme Inhibitors
  • Genotype
  • Sodium-Restricted Diet
• 2013

  Regulation of renin secretion by renal juxtaglomerular cells

  Friis, U. G., Madsen, K., Stubbe, J., Hansen, P. B. L., Svenningsen, P., Bie, P., Skøtt, O. & Jensen, B. L., 2013, In: Pflügers Archiv - European Journal of Physiology. 465, 1, p. 25-37

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Renin
  • Kidney
  • Cyclic AMP
  • Cyclic GMP
  • Receptors, Prostaglandin E, EP2 Subtype

• Renal renin secretion as regulator of body fluid homeostasis

  Damkjær, M., Isaksson, G. L., Stubbe, J., Jensen, B. L., Assersen, K. B. & Bie, P., Jan 2013, In: Pflügers Archiv - European Journal of Physiology. 465, 1, p. 153-165

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Body fluids
  • Body Fluids
  • Renin
  • Blood pressure
  • Sodium

• The effects of calcineurin inhibitors on prostanoid synthesis: a randomized cross-over study in healthy humans

  Ozbay, L. A., Stubbe, J., Jespersen, B. & Jensen, B. L., 2013, In: Transplant International. 26, 2, p. 131-137

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Calcineurin Inhibitors
  • Tacrolimus
  • Prostaglandins
  • Cross-Over Studies
  • Cyclooxygenase 2
• 2012

  Niacin and biosynthesis of PGD₂ by platelet COX-1 in mice and humans

  Song, W-L., Stubbe, J., Ricciotti, E., Alamuddin, N., Ibrahim, S., Crichton, I., Prempeh, M., Lawson, J. A., Wilensky, R. L., Rasmussen, L. M., Puré, E. & FitzGerald, G. A., 2012, In: Journal of Clinical Investigation. 122, 4, p. 1459-68 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prostaglandins D
  • Niacin
  • Blood Platelets
  • Prostaglandins E
  • Thromboxanes

• Ulcerating and stenosing enteropathy treated with misoprostol: a case report with analysis of prostaglandin metabolism

  Havelund, T., Jensen, B. L., Vinholt, P. J., Engvad, B. & Stubbe, J., 2012, In: European Journal of Gastroenterology and Hepatology. 24, 10, p. 1238-1241

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Misoprostol
  • Prostaglandins
  • Synthetic Prostaglandins
  • Capsule Endoscopy
  • Prostaglandins E
• 2010

  Cyclooxygenase-2-dependent prostacyclin formation and blood pressure homeostasis: targeted exchange of cyclooxygenase isoforms in mice

  Yu, Y., Stubbe, J., Ibrahim, S., Song, W., Symth, E. M., Funk, C. D. & FitzGerald, G. A., 5. Feb 2010, In: Circulation Research. 106, 2, p. 337-45 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Epoprostenol
  • Prostaglandin-Endoperoxide Synthases
  • Cyclooxygenase 2
  • Protein Isoforms
  • Homeostasis

• Targeted deletions of cyclooxygenase-2 and atherogenesis in mice

  Hui, Y., Ricciotti, E., Crichton, I., Yu, Z., Wang, D., Stubbe, J., Wang, M., Puré, E. & FitzGerald, G. A., 22. Jun 2010, In: Circulation. 121, 24, p. 2654-60 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclooxygenase 2
  • Atherosclerosis
  • T-Lymphocytes
  • Prostaglandins
  • Macrophages
• 2009

  Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel

  Svenningsen, P., Bistrup, C., Friis, U. G., Bertog, M., Haerteis, S., Krueger, B., Stubbe, J., Jensen, O. N., Thiesson, H. C., Uhrenholt, T. R., Jespersen, B., Jensen, B. L., Korbmacher, C. & Skøtt, O., 1. Jan 2009, In: Journal of the American Society of Nephrology. 20, 2, p. 299-310

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Epithelial Sodium Channels
  • Fibrinolysin
  • Nephrotic Syndrome
  • Urine
  • Amiloride

• Prostaglandin F2alpha elevates blood pressure and promotes atherosclerosis

  Yu, Y., Lucitt, M. B., Stubbe, J., Cheng, Y., Friis, U. G., Hansen, P. B., Jensen, B. L., Smyth, E. M. & FitzGerald, G. A., 12. May 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 19, p. 7985-90 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Dinoprost
  • Prostaglandins
  • Atherosclerosis
  • Blood Pressure
  • Prostaglandins F
• 2007

  Postnatal adrenalectomy impairs urinary concentrating ability by increased COX-2 and leads to renal medullary injury.

  Stubbe, J., Madsen, K., Nielsen, F. T., Bonde, R. K., Skøtt, O. & Jensen, B. L., 1. Sep 2007, In: American Journal of Physiology - Renal Physiology. 293, 3, p. F780-F789 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Adrenalectomy
  • Corticosterone
  • Cyclooxygenase 2
  • parecoxib
  • Osmolar Concentration
• 2006

  Glucocorticoid impairs growth of kidney outer medulla and accelerates loop of Henle differentiation and urinary concentrating capacity in rat kidney development.

  Stubbe, J., Madsen, K., Nielsen, F. T., Skøtt, O. & Jensen, B. L., 1. Oct 2006, In: American Journal of Physiology - Renal Physiology. 291, 4, p. F812-822 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Kidney Medulla
  • Proliferating Cell Nuclear Antigen
  • Weaning
  • Glucocorticoids
  • Kidney
• 2005

  Prostaglandin E2 EP2 and EP4 receptor activation mediates cAMP-dependent hyperpolarization and exocytosis of renin in juxtaglomerular cells

  Friis, U. G., Stubbe, J., Uhrenholt, T. R., Svenningsen, P., Nüsing, R. M., Skøtt, O. & Jensen, B. L., 2005, In: American Journal of Physiology - Renal Physiology. 289, 5, p. F989-F997 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prostaglandins E
  • Renin
  • Dinoprostone
  • butaprost
  • 6-isopropoxy-9-oxoxanthene-2-carboxylic acid
• 2004

  Cycloxygenase-2 is expressed in vasculature of normal and ischemic adult human kidney and is colocalized with vascular PGE2 EP4 receptors.

  Therland, K. L., Stubbe, J., Thiesson, H., Ottosen, P. D., Walter, S., Sørensen, G. L., Skøtt, O. & Jensen, B. L., 2004, In: Journal of the American Society of Nephrology. 15, p. 1189-1198 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Cycloxygenase-2 is expressed in vasculature of normal and ischemic adult human kidney and is colocalized with vascular prostaglandin E2 EP4 receptors

  Therland, K. L., Stubbe, J., Thiesson, H. C., Ottosen, P. D., Walter, S., Sørensen, G. L., Skøtt, O. & Jensen, B. L., May 2004, In: Journal of the American Society of Nephrology. 15, 5, p. 1189-98 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Receptors, Prostaglandin E, EP4 Subtype
  • Cyclooxygenase 2
  • Dinoprostone
  • Blood Vessels
  • Kidney

• Low endogenous glucocorticoid allows induction of kidney cortical cyclooxygenase-2 during postnatal rat development

  Madsen, K., Stubbe, J., Skøtt, O., Yang, T., Bachmann, S. & Jensen, B. L., 2004, In: American Journal of Physiology - Renal Physiology. 286, 1, p. f26-f37 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclooxygenase 2
  • Glucocorticoids
  • Kidney
  • Corticosterone
  • Parturition

• The renin-angiotensin system in kidney development: role of COX-2 and adrenal steroids

  Jensen, B. L., Stubbe, J., Madsen, K., Nielsen, F. T. & Skøtt, O., 2004, In: Acta Physiologica Scandinavica. 181, 4, p. 549-559 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclooxygenase 2
  • Renin-Angiotensin System
  • Steroids
  • Angiotensin II
  • Kidney
• 2003

  Cyclooxygenase-2 contributes to elevated renin in the early postnatal period in rats

  Stubbe, J., Jensen, B. L., Bachmann, S., Morsing, P. & Skøtt, O., 2003, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 284, 5, p. 1179-1189

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cyclooxygenase 2
  • Renin
  • Messenger RNA
  • parecoxib
  • Kidney
• 2001

  Expression of Prostaglandin E2 EP2 and EP4 receptors in the rat kidney

  Jensen, B. L., Stubbe, J., Hansen, P. B., Andreasen, D. & Skøtt, O., 2001, In: American Journal of Physiology - Renal Physiology. 280, p. 1001-1009

  Research output: Contribution to journal › Journal article › Research

• Localization of prostaglandin E(2) EP2 and EP4 receptors in the rat kidney

  Jensen, B. L., Stubbe, J., Hansen, P. B., Andreasen, D. & Skøtt, O., 2001, In: American Journal of Physiology: Renal Physiology. 280, 6, p. F1001-9

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Prostaglandins E
  • Rectum
  • butaprost
  • Kidney
  • Kidney Medulla