Jonas Mengel-From

MSc, PhD

  • J.B. Winsløws Vej 9 B, st. tv.

    5000 Odense C

    Denmark

20022019
If you made any changes in Pure these will be visible here soon.

Personal profile

Research areas

Genetic epidemiology, epigenetics, pigment genetics and aging research.

Curriculum

Education

  • Ph.d. University of Copenhagen, 2008.
  • Master of Science, University of Southern Denmark, 2002.

Academic carreer

  • Post.doc. at the Department of Epidemiology, University of Southern Denmark, 2009 -
  • Forensic geneticist at the Department of Forensic Medicine, University of Copenhagen, 2008 - 2009.
  • PhD-student at the Department of Forensic Medicine, University of Copenhagen, Københavs Universistet, 2004 - 2008.
  • Forensic geneticist at the Department of Forensic Medicine, University of Copenhagen, 2003 - 2004.
  • Research assistant at the Department of Forensic Medicine, University of Copenhagen, 2002 - 2003.

Internationale experience

  • PhD student at MRC Human Genetics Unit, Edinburgh 2006-2007.
  • EU program - High Throughput Analysis of Single Nucleotide Polymorphisms (SNPs) for the forensic IDentification of Persons. http://www.snpforid.org 2003-2006.
  • Erasmus exchange at Universitat de Barcelona 2000.

Peer reviewed
Mengel-From J, Borsting C, Sanchez JJ, Eiberg H, Morling N. Determination of cis/trans phase of variations in the MC1R gene with allele-specific PCR and single base extension. Electrophoresis. 2008 Dec; 29(23):4780-7.

Eiberg H, Troelsen J, Nielsen M, Mikkelsen A, Mengel-From J, Kjaer K, Hansen L. Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression. Human Genetics. 2008, 123(2):177-187.

Mengel-Jorgensen,J., Jensen,S.S., Rasmussen,A., Poehlsgaard,J., Iversen,J.J.L. & Kirpekar,F. Modifications in Thermus thermophilus 23 S ribosomal RNA are centered in regions of RNA-RNA contact. Journal of biological chemistry. (2006). 281: (31), 22108-22117.

Mengel-Jorgensen J, Sanchez JJ, Borsting C, Kirpekar F & Morling N. Typing of multiple SNPs using ribonuclease cleavage of DNA/RNA chimeric single base extension primers and detection by MALDI-TOF mass spectrometry. Analytical chemistry. (2005). 77: (16), 5229-5235.

Mengel-Jorgensen J, Sanchez JJ, Borsting C, Kirpekar F & Morling N. MALDI-TOF mass spectrometric detection of multiplex single base extended primers. A study of 17 y-chromosome single-nucleotide polymorphisms. Analytical chemistry. (2004). 76: (20), 6039-6045.

Madsen CT, Mengel-Jorgensen J, Kirpekar F, Douthwaite S. Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. Nucleic Acids Res. 2003, 31, 4738-46.

Mengel-Jorgensen J and Kirpekar F. Detection of pseudouridines and other modifications in tRNA cyanoethylation and MALDI mass spectrometry. Nucleic Acids Res. 2002, 30: e135. 

Other scientific contributions 

Wächter A, Mengel-From J, Borsting C, Morling N. A 50 SNP-multiplex mass spectrometry assay for human identification. Forensic Science International: Genetic Supplement Series. 2008, 1:487-9.

Mengel-Jorgensen J, Wächter A, Børsting C, Sanchez JJ, Morling N PCR and SBE multiplexes for determination of SNPs associated with hair and eye colours in humans. DNA in forensic, Innsbruck, Austria, September 2006.

Mengel-Jorgensen J, Borsting C, Sanchez JJ, Morling N. Gene variations associated with hair and eye colours in humans 13th European Society for Pigment Cell Research, Barcelona, Spain. Pigment Cell research 2006, 19, 5, 520.

Mengel-From,J., Eiberg,H., Borsting,C. & Morling,N. Genetic screening of 15 SNPs in the MC1R gene in relation to hair colour in Danes. Elsevier (2006).55-57. Progress in Forensic Genetics 11.

Mengel-From,J., Sanchez Sanchez,J.J., Borsting,C., Kirpekar,F. & Morling,N. Multiplex Y chromosome SNP genotyping using MALDI-TOF mass spectrometry. Elsevier (2004).15-17. Progress in Forensic Genetics 10.

Sanchez,J.J., Borsting,C., Hernandez,A., Mengel-From,J. & Morling,N. Y chromosome SNP haplogroups in Danes, Greenlanders and Somalis. Elsevier (2004).347-349. Progress in Forensic Genetics 10.

Phillips C., Lareu M., Brion M., Sobrino B., Carracedo A., Boersting C., Kirpekar F., Mengel-Joergensen J., Sanchez J.J., Morling N., Syndercombe Court D., Balogh K., Bogus M., Bender K., SchneiderP.M. Selecting Single Nucleotide Polymorphisms for Forensic Applications Elsevier International Congress Series 1261 (2004) Progress in Forensic Genetics 10.

Fingerprint Dive into the research topics where Jonas Mengel-From is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 41 Similar Profiles
Cognition Medicine & Life Sciences
Twin Studies Medicine & Life Sciences
Alleles Medicine & Life Sciences
Eye Color Medicine & Life Sciences
Monozygotic Twins Medicine & Life Sciences
Hair Color Medicine & Life Sciences
Single Nucleotide Polymorphism Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2002 2019

2 Downloads (Pure)

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies

Mengel-From, J., Svane, A. M., Pertoldi, C., Kristensen, T. N., Loeschcke, V., Skytthe, A., Christensen, K., Lindahl-Jacobsen, R., Hjelmborg, J. & Christiansen, L., 15. Mar 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fruit
Parents
DNA
Maternal Age
Health
5 Downloads (Pure)

Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

Lund, J. B., Li, S., Christensen, K., Mengel-From, J., Thinggaard, M. S., Marioni, R. E., Starr, J., Pattie, A., Deary, I. J., Baumbach, J. & Tan, Q., 2019, In : Aging Cell. 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
DNA Methylation
Epigenomics
Sex Characteristics
20 Downloads (Pure)

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

Sørensen, T. I. A. & DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), Aug 2019, In : Acta Neuropathologica. 138, 2, p. 237-250

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Lewy Body Disease
Alzheimer Disease
Mutation
Neurodegenerative Diseases
Alleles
26 Downloads (Pure)

Epigenome-wide association study of leukocyte telomere length

Lee, Y., Sun, D., Ori, A. P. S., Lu, A. T., Seeboth, A., Harris, S. E., Deary, I. J., Marioni, R. E., Soerensen, M., Mengel-From, J., Hjelmborg, J., Christensen, K., Wilson, J. G., Levy, D., Reiner, A. P., Chen, W., Li, S., Harris, J. R., Magnus, P., Aviv, A. & 2 others, Jugessur, A. & Horvath, S., 26. Aug 2019, In : Aging. 11, 16, p. 5876-5894

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Telomere
Epigenomics
Women's Health
DNA Methylation
Circadian Rhythm
8 Downloads (Pure)
Open Access
File
Monozygotic Twins
Cell Differentiation
HLA-C Antigens
Comb and Wattles
Nucleic Acid Regulatory Sequences

Activities 2010 2019

  • 6 Conference presentations
  • 5 Conference organisation or participation
  • 5 Talks and presentations in private or public companies

Molecular biomarkers of aging - experiences from the Danish Twin Register and Aging Biobank

Jonas Mengel-From (Keynote speaker)
8. Jul 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

49th Annual Meeting of the Behavior Genetics Association

Jonas Mengel-From (Participant)
26. Jun 201929. Jun 2019

Activity: Attending an eventConference organisation or participation

Implementation of Digital Data Collection for Cognitive Performance in the Long Life Family Study

Jonas Mengel-Jørgensen (Speaker)
Nov 2018

Activity: Talks and presentationsConference presentations

Press / Media

New hair colour genes identified

Jonas Mengel-Jørgensen

16/04/2018

1 Media contribution

Press/Media: Press / Media

Shot of Klotho Boosts Memory In Aging and Diseased Mice

Jonas Mengel-Jørgensen

15/08/2017

1 Media contribution

Press/Media: Press / Media

VIDENSKAB: Broccoli kan indeholde ' ungdomseliksir'

Jonas Mengel-Jørgensen

19/02/2017

1 item of Media coverage

Press/Media: Press / Media

Broccolieliksir gør gamle mus unge igen

Jonas Mengel-Jørgensen

13/02/2017

1 item of Media coverage

Press/Media: Press / Media