Personal profile

Research interests

The impact of Noncoding RNAs (ncRNAs) such as microRNAs and, more recently, long ncRNAs (LncRNAs) onto eukaryotic gene regulation has just started to be understood. The research Group of Jan-Wilhelm Kornfeld lab would like to take part in this 'Noncoding RNA revolution' by identifying novel ncRNAs and elucidating their role in homeostatic circuits regulating energy homeostasis in health and disease. We apply state-of-the art techniques such as next-generation sequencing, the generation of transgenic mouse models and in vivo anti-ncRNA approaches to ultimately better understand the intricate biology of disease-associated ncRNAs. Our ultimatate goal is to define novel sequence-specific anti-ncRNAs therapeutics for anti-obesity intervention.

Research areas

Noncoding RNAs, Energy Metabolism, Obesity, Type 2 Diabetes, Adipose tissue, Epigenetics

Research areas

  • Bioinformatics
  • Antisense and siRNA
  • Obesity
  • Fat cell development and function
  • Cirrhosis

Fingerprint

Dive into the research topics where Jan-Wilhelm Kornfeld is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Researchers

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or