Research output per year
Research output per year
Personal profile
Research interests
The impact of Noncoding RNAs (ncRNAs) such as microRNAs and, more recently, long ncRNAs (LncRNAs) onto eukaryotic gene regulation has just started to be understood. The research Group of Jan-Wilhelm Kornfeld lab would like to take part in this 'Noncoding RNA revolution' by identifying novel ncRNAs and elucidating their role in homeostatic circuits regulating energy homeostasis in health and disease. We apply state-of-the art techniques such as next-generation sequencing, the generation of transgenic mouse models and in vivo anti-ncRNA approaches to ultimately better understand the intricate biology of disease-associated ncRNAs. Our ultimatate goal is to define novel sequence-specific anti-ncRNAs therapeutics for anti-obesity intervention.
Research areas
Noncoding RNAs, Energy Metabolism, Obesity, Type 2 Diabetes, Adipose tissue, Epigenetics
Research areas
- Bioinformatics
- Antisense and siRNA
- Obesity
- Fat cell development and function
- Cirrhosis
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Nanopore sequencing unveils the complexity of the cold-activated murine brown adipose tissue transcriptome
Engelhard, C. A., Khani, S., Derdak, S., Bilban, M. & Kornfeld, J. W., 18. Aug 2023, In: iScience. 26, 8, 24 p., 107190.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Downloads (Pure) -
Studying The Vascular Adipose Niche Using Organotypic Spheriods
Davidsen, L. I., Hagberg, C. E., Ebbesen, M. F. & Kornfeld, J-W., 23. Mar 2023.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Studying The Vascular Adipose Niche Using Organotypic Spheriods
Davidsen, L. I., Hagberg, C. E., Ebbesen, M. F. & Kornfeld, J-W., 14. Mar 2023.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Comprehensive transcriptional profiling and mouse phenotyping reveals dispensable role for adipose tissue selective long noncoding RNA Gm15551
Engelhard, C. A., Huang, C., Khani, S., Kasparek, P., Prochazka, J., Rozman, J., Reguera, D. P., Sedlacek, R. & Kornfeld, J. W., Jun 2022, In: Non-coding RNA. 8, 3, 32.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Downloads (Pure) -
The function of proto-adipokine AOC3 during adipose tissue dysfunction in metabolic diseases
Topel Batarlar, H., Davidsen, L. I., Egedal, N. M., Park, J. H., Larsen, B. D. M. & Kornfeld, J-W., 30. May 2022.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research
Activities
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Conference talk 'Long noncoding RNAs in Energy Homeostasis and Metabolic Disease'
Jan-Wilhelm Kornfeld (Guest lecturer)
11. Dec 2019Activity: Talks and presentations › Talks and presentations in private or public companies
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Workshop 'Does diabetes start from before conception? – An transgenerational perspective on Metabolic Disease'
Jan-Wilhelm Kornfeld (Guest lecturer) & Joo Hyun Park (Guest lecturer)
27. Nov 2019Activity: Talks and presentations › Guest lectures, external teaching and course activities at other universities
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Conference talk 'Long noncoding RNAs in Energy Homeostasis and Metabolic Diseases'
Jan-Wilhelm Kornfeld (Lecturer)
12. Sept 2019Activity: Talks and presentations › Conference presentations
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Conference talk 'Plasticity of BAT signaling responses during cold exposure and metabolic disease'
Jan-Wilhelm Kornfeld (Lecturer)
3. Jun 2019Activity: Talks and presentations › Talks and presentations in private or public companies
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ADIPOSIGN Opening Sympoisum
Susanne Mandrup (Organizer), Marianne Holmer (Panel member), Jakob Møller-Jensen (Panel member), Jan-Wilhelm Kornfeld (Panel member), Zachary Gerhart-Hines (Panel member), M. Madan Babu (Panel member), Matthias Blüher (Panel member), Ruth J F Loos (Panel member), Martin Klingenspor (Panel member) & Christian Wolfrum (Panel member)
27. May 2019Activity: Attending an event › Organisation or participation in workshops, courses or seminars
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Aarhus Universitet -The role of microRNAs in the obese adipose vascular niche
01/11/2023 → 31/10/2026
Project: Other Government Institutions
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Sygeforsikringen "Danmark" - Novel approaches to intergenerational epigenetic inheritance of Metabolic
01/05/2021 → 30/04/2025
Project: Research
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Novo Nordisk Fonden - Challenge Programme 2018 - ADIPOSIGN - Center for Adipocyte Signaling JK
01/05/2019 → 31/12/2024
Project: Research
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Novo Nordisk Challenge Programme - ADIPOSIGN - Center for Adipocyte Signaling
Mandrup, S., Kornfeld, J., Quesada-Lopez, T. P., Mikkelsen, V. A., Josephrajan, A., Malmros, R. V., Gerhart-Hines, Z., Babu, M. M., Elmelund-Præstekær, L. C. B., Wishoff, M., Nielsen, R. & Marcher, A.
01/01/2019 → 31/12/2024
Project: Research
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Novo Nordisk Fonden - Nutrient-chromatin crosstalk in adipose tissue health and metabolic disease (HISTONE HEALTH)
01/01/2022 → 31/12/2024
Project: Research
Press/Media
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PRM / Ny forskning: Spøgelses-gener holder diabetes i skak
03/02/2020
1 Media contribution
Press/Media: Press / Media
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PRM / Ny forskning: Spøgelses-gener holder diabetes i skak
03/02/2020
1 Media contribution
Press/Media: Press / Media
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Spøgelses-gen har betydning for stofskiftefunktionen
03/02/2020
1 Media contribution
Press/Media: Press / Media
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Ny forskning: Spøgelses-gener holder diabetes i skak
03/02/2020
1 Media contribution
Press/Media: Press / Media
Teaching & Supervision
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BMB822 - Modern Developments and Technologies in Molecular Cell Biology
Jan-Wilhelm Kornfeld & 01/01/2018 → …
Course: Teaching
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NAT501 - First year project - Responsible supervisor
Jan-Wilhelm Kornfeld & 01/01/2018 → …
Course: Teaching