John Hjort Ipsen

  • Campusvej 55

    5230 Odense M

    Denmark

1986 …2019
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Research Output 1986 2019

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Journal article
2019
19 Downloads (Pure)

A Multi-Scale Approach to Membrane Remodeling Processes

Pezeshkian, W., König, M., Marrink, S. J. & Ipsen, J. H., 23. Jul 2019, In : Frontiers in Molecular Biosciences. 6, 7 p., 59.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Membranes
Shiga Toxin
Molecular Dynamics Simulation
Conformations
Molecular dynamics
2018
96 Downloads (Pure)

C24 Sphingolipids Govern the Transbilayer Asymmetry of Cholesterol and Lateral Organization of Model and Live-Cell Plasma Membranes

Courtney, K. C., Pezeshkian, W., Raghupathy, R., Zhang, C., Darbyson, A., Ipsen, J. H., Ford, D. A., Khandelia, H., Presley, J. F. & Zha, X., 24. Jul 2018, In : Cell Reports. 24, 4, p. 1037-1049 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Sphingolipids
Cell membranes
Sphingomyelins
Cholesterol
Cell Membrane

Non-Equilibrium Thermodynamics of Self-Replicating Protocells

Fellermann, H., Corominas-Murtra, B., Hansen, P. L., Ipsen, J. H., Solé, R. & Rasmussen, S., 2018, (Accepted/In press) In : Scientific Reports. 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

nonequilibrium thermodynamics
thermodynamic cycles
cycles
biology
thermodynamics
124 Downloads (Pure)

The tension of framed membranes from computer simulations

Hamkens, D., Jeppesen, C. & Ipsen, J. H., Mar 2018, In : European Physical Journal E. 41, 3, 11 p., 42.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Computer Simulation
computerized simulation
membranes
Membranes
Computer simulation
2017

Capturing suboptical dynamic structures in lipid bilayer patches formed from free-standing giant unilamellar vesicles

Bhartia, T., Cornelius, F. & Ipsen, J. H., 2017, In : Nature Protocols (Print). 12, 8, p. 1563-1575

Research output: Contribution to journalJournal articleResearchpeer-review

Unilamellar Liposomes
Lipid Bilayers
Membranes
Atomic Force Microscopy
Lipids
92 Downloads (Pure)

Cholera toxin B subunit induces local curvature on lipid bilayers

Pezeshkian, W., Nåbo, L. J. & Ipsen, J. H., 2017, In : FEBS Open Bio. 7, 11, p. 1638-1645

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Lipid bilayers
Cholera Toxin
Lipid Bilayers
Cell membranes
Membranes
120 Downloads (Pure)

Effects of seaweed sterols fucosterol and desmosterol on lipid membranes

Mouritsen, O. G., Bagatolli, L. A., Duelund, L., Garvik, O., Ipsen, J. H. & Simonsen, A. C., 2017, In : Chemistry and Physics of Lipids. 205, p. 1-10

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Desmosterol
Seaweed
Sterols
Membrane Lipids
Ergosterol
133 Downloads (Pure)

Mechanism of Shiga Toxin Clustering on Membranes

Pezeshkian, W., Gao, H., Arumugam, S., Becken, U., Bassereau, P., Florent, J. C., Ipsen, J. H., Johannes, L. & Shillcock, J. C., 2017, In : ACS Nano. 11, 1, p. 314-324 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Shiga Toxin
membranes
Membranes
Molecules
molecules

Membrane tubulation in lipid vesicles triggered by the local application of calcium ions

Ali Doosti, B., Pezeshkian, W., Bruhn, D. S., Ipsen, J. H., Khandelia, H., Jeffries, G. D. M. & Lobovkina, T., 2017, In : Langmuir. 33, 41, p. 11010-11017

Research output: Contribution to journalJournal articleResearchpeer-review

Lipids
lipids
calcium
Calcium
Ions
125 Downloads (Pure)

Numerical insights into the phase diagram of p-atic membranes with spherical topology

Hansen, A. G., Ramakrishnan, N., Sunil Kumar, P. B. & Ipsen, J. H., 2017, In : The European Physical Journal E: Soft Matter and Biological Physics. 40, 10 p., 32.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Phase diagrams
topology
phase diagrams
Topology
membranes
2016
74 Downloads (Pure)

Gaussian vector fields on triangulated surfaces

Ipsen, J. H., 2016, In : International Journal of Advances in Engineering Sciences and Applied Mathematics. 8, 2, p. 121-125

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
membranes
degrees of freedom
elastic deformation
lipids
elastic properties
305 Downloads (Pure)

Membrane invagination induced by Shiga toxin B-subunit: From molecular structure to tube formation

Pezeshkian, W., Hansen, A. G., Johannes, L., Khandelia, H., Shillcock, J. C., Kumar, P. B. S. & Ipsen, J. H., 2016, In : Soft Matter. 2016, 12, p. 5164-5171

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Shiga Toxin
Clathrin
Molecular structure
molecular structure
tubes
100 Downloads (Pure)

Spatial distribution and activity of Na +/K +-ATPase in lipid bilayer membranes with phase boundaries

Bhartia, T., Cornelius, F., Brewer, J. R., Bagatolli, L., Simonsen, A. C., Ipsen, J. H. & Mouritsen, O. G., 2016, In : BBA Biomembranes. 1858, 6, p. 1390-1399

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
2015
95 Downloads (Pure)

Curvature inducing macroion condensation driven shape changes of fluid vesicles

Sreeja, K. K., Ipsen, J. H. & Kumar, P. B. S., 2015, In : Journal of Chemical Physics. 143, 19, 8 p., 194902.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Membrane properties of Enchytraeus albidus originating from contrasting environments: a comparative analysis

Fisker, K. V., Bouvrais, H., Overgaard, J., Schottner, K., Ipsen, J. H. & Holmstrup, M., 2015, In : Journal of Comparative Physiology B: Biochemical, Systems, and Environmental Physiology. 185, 4, p. 389-400

Research output: Contribution to journalJournal articleResearchpeer-review

Monte Carlo simulations of fluid vesicles

Sreeja, K. K., Ipsen, J. H. & Kumar, P. B. S., 2015, In : Journal of Physics: Condensed Matter. 27, 27, 14 p., 273104.

Research output: Contribution to journalJournal articleResearchpeer-review

Organelle morphogenesis by active membrane remodeling

Ramakrishnan, N., Ipsen, J. H., Rao, M. & Kumar, P. B. S., 2015, In : Soft Matter. 11, 12, p. 2387-2393

Research output: Contribution to journalJournal articleResearchpeer-review

Preparing giant unilamellar vesicles (GUVs) of complex lipid mixtures on demand: Mixing small unilamellar vesicles of compositionally heterogeneous mixtures

Bhartia, T., Husen, P. J., Brewer, J. R., Bagatolli, L., Hansen, P. L., Ipsen, J. H. & Mouritsen, O. G., 2015, In : B B A - Biomembranes. 1848, 12, p. 3175-3180 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

The effects of globotriaosylceramide tail saturation level on bilayer phases

Pezeshkian, W., Chaban, V. V., Johannes, L., Shillcock, J., Ipsen, J. H. & Khandelia, H., 4. Feb 2015, In : Soft Matter. 11, 7, p. 1352-61 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Shiga Toxin
Phase behavior
lipids
saturation
Lipids
2014

Buffers Affect the Bending Rigidity of Model Lipid Membranes

Bouvrais, H., Duelund, L. & Ipsen, J. H., 2014, In : Langmuir. 30, 1, p. 13-16

Research output: Contribution to journalJournal articleResearchpeer-review

Fluid domain patterns in free-standing membranes captured on a solid support

Bhartia, T., Husen, P. R., Ipsen, J. H., Bagatolli, L. & Simonsen, A. C., 2014, In : B B A - Biomembranes. 1838, 10, p. 2503-2510

Research output: Contribution to journalJournal articleResearchpeer-review

Unilamellar Liposomes
Membranes
Fluids
Liquids
Lipids

Lipophilic Contaminants Influence Cold Tolerance of Invertebrates through Changes in Cell Membrane Fluidity

Holmstrup, M., Bouvrais, H., Westh, P., Wang, C. H., Slotsbo, S., Waagner, D., Enggrob, K. & Ipsen, J. H., 2014, In : Environmental Science & Technology. 48, 16, p. 9797-9803

Research output: Contribution to journalJournal articleResearchpeer-review

2013

Analysis of the shape fluctuations of reconstituted membranes using GUVs made from lipid extracts of invertebrates

Bouvrais, H., Holmstrup, M., Westh, P. & Ipsen, J. H., 2013, In : Biology Open. 2, 4, p. 373-378

Research output: Contribution to journalJournal articleResearchpeer-review

Composition, structure and properties of POPC-triolein mixtures. Evidence of triglyceride domains in phospholipid bilayers

Duelund, L., Vestergaard Jensen, G., Hannibal-Bach, H. K., Ejsing, C. S., Skov Pedersen, J., Inkeri Pakkanen, K. & Ipsen, J. H., 2013, In : BBA General Subjects. 1828, 8, p. 1909-1917

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Triolein
Phosphorylcholine
Phospholipids
Membranes
Electron Spin Resonance Spectroscopy

Linking membrane physical properties and low temperature tolerance in arthropods Cryobiology

Waagner, D., Bouvrais, H., Ipsen, J. H. & Holmstrup, M., 2013, In : Cryobiology. 67, 3, p. 383-385

Research output: Contribution to journalJournal articleResearchpeer-review

Membrane-Mediated Aggregation of Curvature-inducing Nematogens and Membrane Tubulation

Ipsen, J. H., 2013, In : Biophysical Journal. 104 , p. 1018-1028

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
2012

Aktive membraner med Na+/K+-pumper. Lipid-proteinvekselvirkninger i biologiske membraner

Bouvrais, H., Cornelius, F., Ipsen, J. H. & Mouritsen, O. G., 2012, In : Dansk Kemi. 12, p. 14-15

Research output: Contribution to journalJournal articleCommunication

A method for analysis of lipid vesicle domain structure from confocal image data

Husen, P. R., Fidorra, M., Hartel, S., Bagatolli, L. & Ipsen, J. H., 2012, In : European Biophysics Journal. 41, 2, p. 161-175

Research output: Contribution to journalJournal articleResearchpeer-review

Lipids
Membranes
Fluorescence Microscopy

Intrinsic reaction-cycle time scale of Na+,K+-ATPase manifests itself in the lipid-protein interactions of nonequilibrium membranes

Bouvrais, H., Cornelius, F., Ipsen, J. H. & Mouritsen, O. G., 2012, In : Proceedings of the National Academy of Sciences of the United States of America.

Research output: Contribution to journalJournal articleResearchpeer-review

Intrinsic reaction-cycle time scale of Na+,K+-ATPase manifests itself in the lipid-protein interactions of non-equilibrium membranes

Bouvrais, H., Cornelius, F., Ipsen, J. H. & Mouritsen, O. G., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, p. 18442-18446

Research output: Contribution to journalJournal articleResearchpeer-review

Membranen sladrer om ion-pumpers funktion

Bouvrais, H., Cornelius, F., Ipsen, J. H. & Mouritsen, O. G., 2012, In : Aktuel Naturvidenskab. 6, p. 42-47 5 p.

Research output: Contribution to journalJournal articleCommunication

Morphometric image analysis of giant vesicles: a new tool for quantitative thermodynamics studies of phase-separation in lipid membranes

Husen, P. R., Arriaga, L., Monroy, F., Ipsen, J. H. & Bagatolli, L., 2012, In : Biophysical Journal. 103, 11, p. 2304-2310

Research output: Contribution to journalJournal articleResearchpeer-review

Membrane Lipids
Phase separation
Unilamellar Liposomes
Image analysis
Cholesterol

Role of disclinations in determining the morphology of deformable fluid interfaces

Ramakrishnan, N., Ipsen, J. H. & Kumar, P. B. S., 2012, In : Soft Matter. 8, 11, p. 3058-3061 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2011

Advantages of statistical analysis of giant vesicle flickering for bending elasticity measurements

Méléard, P., Pott, T., Bouvrais, H. & Ipsen, J. H., 2011, In : The European Physical Journal E: Soft Matter and Biological Physics. 34, 10, 14 p.

Research output: Contribution to journalJournal articleResearch

Correlation between the ripple phase and stripe domains in membranes

Bernchou, U., Midtiby, H., Ipsen, J. H. & Simonsen, A. C., 2011, In : B B A - Biomembranes. 1808, p. 2849–2858 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Elastic moderation of intrinsically applied tension in lipid membranes

Lomholt, M. A., Loubet, B. & Ipsen, J. H., 2011, In : Physical Review E. Statistical, Nonlinear, and Soft Matter Physics. 83, p. 011913-1 - 011913-4 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Mechanics and dynamics of triglyceride-phospholipid model membranes: Implications for cellular properties and function

Pakkanen, K. I., Duelund, L., Qvortrup, K., Pedersen, J. S. & Ipsen, J. H., 2011, In : BBA General Subjects. 1808, 8, p. 1947-1956 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Modeling anisotropic elasticity of fluid membranes

Ramakrishnan, N., Kumar, P. B. S. & Ipsen, J. H., 25. Aug 2011, In : Macromolecular Theory and Simulations. 20, 7, p. 446-450 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2010

An outlook on organization of lipids in membranes: Searching for a realistic connection with the organization of biological membranes

Bagatolli, L., Ipsen, J. H., Simonsen, A. C. & Mouritsen, O. G., 2010, In : Progress in Lipid Research. 49, p. 378-389 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Impact of membrane-anchored fluorescent probes on the mechanical properties of lipid bilayers

Bouvrais, H., Pott, T., Bagatolli, L., Ipsen, J. H. & Méléard, P., 2010, In : Biochimica et Biophysica Acta - Biomembranes. 1798, 7, p. 1333-1337

Research output: Contribution to journalJournal articleResearchpeer-review

Monte Carlo Simulations of fluid vesicles with in-plane orientational order

Ramakrishnan, N., Kumar, P. B. S. & Ipsen, J. H., 2010, In : Physical Review E. 81, 10, p. 041922 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Monte Carlo simulations of fluid vesicles with in-plane orientational ordering

Ramakrishnan, N., Sunil Kumar, P. B. & Ipsen, J. H., 2010, In : Physical Review E.

Research output: Contribution to journalJournal articleResearchpeer-review

Phase coexistence in a triolein–phosphatidylcholine system. Implications for lysosomal membrane properties

Pakkanen, K. I., Duelund, L., Vuento, M. & Ipsen, J. H., 1. Feb 2010, In : Chemistry and Physics of Lipids. 163, 2, p. 218-227 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

335 Downloads (Pure)

Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes

Khandelia, H., Duelund, L., Pakkanen, K. I. & Ipsen, J. H., 2010, In : P L o S One. 5, 9, p. e12811

Research output: Contribution to journalJournal articleResearchpeer-review

File
Triolein
blisters
triolein
lipid bilayers
Lipid bilayers

Understanding detergent effects on lipid membranes - A model study of lysolipids

Henriksen, J., Andresen, T., Feldborg, L., Duelund, L. & Ipsen, J. H., 2010, In : Biophysical Journal. 98, 10, p. 2199-2205 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2009
image analysis
Image analysis
Nucleation
membranes
Membranes

Lipid domains in giant unilamellar vesicles and their correspondence with equilibrium thermodynamic phases: A quantitative fluorescence microscopy imaging approach

Fidorra, M., Garcia, A., Ipsen, J. H., Härtel, S. & Bagatolli, L., 1. Oct 2009, In : Biochimica et Biophysica Acta - Biomembranes. 1788, 10, p. 2142-2149 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Unilamellar Liposomes
Fluorescence microscopy
Optical Imaging
Fluorescence Microscopy
Thermodynamics

Texture of lipid bilayer domains

Jensen, U. B., Brewer, J. R., Midtiby, H. S., Ipsen, J. H., Bagatolli, L. & Simonsen, A. C., 14. Oct 2009, In : Journal of the American Chemical Society. 131, 40, p. 14130-14131

Research output: Contribution to journalJournal articleResearchpeer-review

Lipid bilayers
Lipid Bilayers
Textures
Gels
Lipids
2008

Softening of POPC membranes by magainin

Bouvrais, H., Méléard, P., Pott, T., Jensen, K. J., Brask, J. & Ipsen, J. H., 2008, In : Biophysical Chemistry. 137, 1, p. 7-12 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

The impact of peptides on lipid membranes

Khandelia, H., Ipsen, J. H. & Mouritsen, O. G., 2008, In : BBA General Subjects. 1778, p. 1528-1536

Research output: Contribution to journalJournal articleResearchpeer-review