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Research Output 1982 2019

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Journal article
2019
Polycystic Ovary Syndrome
Mothers
Penis
Denmark
Research
93 Downloads (Pure)

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jørgensen, M. E., Grarup, N. & 9 others, Pedersen, O., Simons, M., Groop, L., Orho-Melander, M., McCarthy, M. I., Melander, O., Rossing, P., Kilpeläinen, T. O. & Hansen, T., Feb 2019, In : Diabetologia. 62, 2, p. 292-305

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Exome
Albuminuria
Meta-Analysis
Kidney Diseases
Type 2 Diabetes Mellitus
45 Downloads (Pure)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W-J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de Las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K-H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H-H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y-D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., 3. Jan 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Mitochondrial Genes
Body Mass Index
Insulin
Adipocytes
Type 2 Diabetes Mellitus
77 Downloads (Pure)

Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Olesen, M. N., Soelberg, K., Debrabant, B., Nilsson, A. C., Lillevang, S. T., Grauslund, J., Brandslund, I., Madsen, J. S., Paul, F., Smith, T. J., Jarius, S. & Asgari, N., 11. Mar 2019, In : Journal of Neuroinflammation. 16, 12 p., 59.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Optic Neuritis
Cerebrospinal Fluid
Cohort Studies
Prospective Studies
Intermediate Filaments

EGFR and EGFR ligands in serum in healthy women: reference intervals and age dependency

Kjær, I. M., Olsen, D. A., Alnor, A., Brandslund, I., Bechmann, T. & Madsen, J. S., 26. Nov 2019, In : Clinical Chemistry and Laboratory Medicine. 57, 12, p. 1948-1955

Research output: Contribution to journalJournal articleResearchpeer-review

Epidermal Growth Factor Receptor
Epidermal Growth Factor
Ligands
Serum
Transforming Growth Factors

Home Management of Warfarin Treatment Through a Real-Time Supervised Telemedicine Solution: A Randomized Controlled Trial

Brasen, C. L., Madsen, J. S., Parkner, T. & Brandslund, I., Feb 2019, In : Telemedicine and e-Health. 25, 2, p. 109-115

Research output: Contribution to journalJournal articleResearchpeer-review

Warfarin
Randomized Controlled Trials
International Normalized Ratio
Point-of-Care Systems
Delivery of Health Care
111 Downloads (Pure)

Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, N. R., Vestergaard, H., Hansen, T., Hansen, T. H., Pedersen, O. & Nielsen, T., Jun 2019, In : Diabetologia. 62, 6, p. 1024-1035

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Type 2 Diabetes Mellitus
Bilophila
Bacterial DNA
Microbiota
Denmark

Myalgisk encefalomyelitis eller kronisk træthedssyndrom

Translated title of the contribution: Myalgic encephalomyelitis or chronic fatigue syndromeBrinth, L., Nielsen, H., Varming, K., Boonen, S. E., Ebsen, A. G., Fernandez-Guerra, P., Schou, A-S., Mehlsen, J., Gregersen, N., Brandslund, I. & Olsen, R. K. J., 10. Jun 2019, In : Ugeskrift for Laeger. 181, 21, 4 p., V08180570.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Fatigue Syndrome
Research
52 Downloads (Pure)

Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey

Pharmacogenomics Education Working Group (PGxEWG), Jun 2019, In : Pharmacogenomics. 20, 9, p. 643-657

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Pharmacy Schools
Pharmacogenetics
Medical Schools
Education
Health Occupations

Polymorphisms in the NFkB, TNF-alpha, IL-1beta, and IL-18 pathways are associated with response to anti-TNF therapy in Danish patients with inflammatory bowel disease

The Danish IBD Genetics Working Group, Apr 2019, In : Alimentary Pharmacology and Therapeutics. 49, 7, p. 890-903

Research output: Contribution to journalJournal articleResearchpeer-review

Interleukin-18
Inflammatory Bowel Diseases
Ulcerative Colitis
Tumor Necrosis Factor-alpha
Crohn Disease

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

CHD Exome+ Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 452-469

Research output: Contribution to journalJournal articleResearchpeer-review

Homeostasis
Lipids
Fats
Exome
White Adipose Tissue
64 Downloads (Pure)

Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants

Sun, J., Have, C. T., Hollensted, M., Grarup, N., Linneberg, A., Pedersen, O., Nielsen, J. S., Rungby, J., Christensen, C., Brandslund, I., Kristiansen, K., Jun, W., Hansen, T. & Gjesing, A. P., 15. Aug 2019, In : PLOS ONE. 14, 8, 10 p., e0220805.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Medical problems
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
diabetes
Glutamate Decarboxylase
Polycystic Ovary Syndrome
Third Pregnancy Trimester
Mothers
Cortisone
Fasting

Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes

Kofoed Kjær, L., Cejvanovic, V., Henriksen, T., Hansen, T., Pedersen, O., Kjeldahl Christensen, C., Torp-Pedersen, C., Alexander Gerds, T., Brandslund, I., Mandrup-Poulsen, T. & Enghusen Poulsen, H., 4. Jun 2019, In : Free Radical Research. 53, 6, p. 694-703

Research output: Contribution to journalJournal articleResearchpeer-review

Medical problems
Type 2 Diabetes Mellitus
Nucleic Acids
RNA
Oxidation
2018
105 Downloads (Pure)

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

Finnish Diabetic Nephropathy Study (FinnDiane), 1. Jul 2018, In : Diabetes. 67, 7, p. 1414-1427

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Genome-Wide Association Study
Diabetic Nephropathies
Type 2 Diabetes Mellitus
Glomerular Filtration Rate
Sample Size
133 Downloads (Pure)

Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis

Loft, N. D., Skov, L., Iversen, L., Gniadecki, R., Dam, T. N., Brandslund, I., Hoffmann, H. J., Andersen, M. R., Dessau, R. B., Bergmann, A. C., Møller Andersen, N., Andersen, P. S., Bank, S., Vogel, U. & Andersen, V., 22. May 2018, In : Pharmacogenomics Journal. 18, 3, p. 494–500

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Psoriasis
Single Nucleotide Polymorphism
Psoriatic Arthritis
Interleukin-13
Pharmacogenetics
176 Downloads (Pure)

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, A., Pedersen, O., Kiebish, M. A., Qvortrup, K., Han, X., Pedersen, B. K., Jastroch, M., Mandrup, S., Kjær, A., Gygi, S. P., Hansen, T., Gillum, M. P., Grarup, N., Emanuelli, B., Nielsen, S., Scheele, C., Tseng, Y. H., Færgeman, N. J. & Gerhart-Hines, Z., 3. Jul 2018, In : Cell Metabolism. 28, 1, p. 159-174.e11

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Homeostasis
Fats
Energy Metabolism
Insulin Resistance
Adipocytes
106 Downloads (Pure)

Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project cohort of newly diagnosed patients with type 2 diabetes: a cohort profile

Christensen, D. H., Nicolaisen, S. K., Berencsi, K., Beck-Nielsen, H., Rungby, J., Friborg, S., Brandslund, I., Christiansen, J. S., Vaag, A., Sørensen, H. T., Nielsen, J. S. & Thomsen, R. W., 1. Apr 2018, In : BMJ Open. 8, 4, 11 p., e017273.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Type 2 Diabetes Mellitus
Research
Diabetes Complications
Albuminuria
Diabetic Neuropathies
78 Downloads (Pure)
Open Access
File
Immunoassay
Ligands
Serum
Limit of Detection
Betacellulin
85 Downloads (Pure)

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Mägi, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 95 others, Prins, B. P., Guo, X., Bielak, L. F., Below, J. E., Bowden, D. W., Chambers, J. C., Kim, Y. J., Ng, M. C. Y., Petty, L. E., Sim, X., Zhang, W., Bennett, A. J., Bork-Jensen, J., Brummett, C. M., Canouil, M., Ec Kardt, K-U., Fischer, K., Kardia, S. L. R., Kronenberg, F., Läll, K., Liu, C-T., Locke, A. E., Luan, J., Ntalla, I., Nylander, V., Schönherr, S., Schurmann, C., Yengo, L., Bottinger, E. P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J. C., Ford, I., Franco, O. H., Frayling, T. M., Giedraitis, V., Hackinger, S., Hattersley, A. T., Herder, C., Ikram, M. A., Ingelsson, M., Jørgensen, M. E., Jørgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C. M., Linneberg, A., Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K. L., Morris, A. D., Nadkarni, G., Pankow, J. S., Peters, A., Sattar, N., Stančáková, A., Strauch, K., Taylor, K. D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D. R., Dupuis, J., Peyser, P. A., Zeggini, E., Loos, R. J. F., Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F. S., Jukema, J. W., Palmer, C. N. A., Grallert, H., Metspalu, A., Dehghan, A., Köttgen, A., Abecasis, G. R., Meigs, J. B., Rotter, J. I., Marchini, J., Pedersen, O., Hansen, T., Langenberg, C., Wareham, N. J., Stefansson, K., Gloyn, A. L., Morris, A. P., Boehnke, M. & McCarthy, M. I., Nov 2018, In : Nature Genetics. 50, 11, p. 1505–1513

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Type 2 Diabetes Mellitus
Genome-Wide Association Study
Epigenomics
Equipment and Supplies

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

Groop, L. C., Leslie, R. D., Grant, S. F. A. & Bone Mineral Density in Childhood Study, Nov 2018, In : Diabetes Care. 41, 11, p. 2396-2403

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Genome-Wide Association Study
Type 2 Diabetes Mellitus
Population Control
Latent Autoimmune Diabetes in Adults
Glycolysis
98 Downloads (Pure)

Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis

Sode, J., Bank, S., Vogel, U., Andersen, P. S., Sørensen, S. B., Bojesen, A. B., Andersen, M. R., Brandslund, I., Dessau, R. B., Hoffmann, H. J., Glintborg, B., Hetland, M. L., Locht, H., Heegaard, N. H. & Andersen, V., 12. Sep 2018, In : BMC Medical Genetics. 19, 16 p., 165.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Tumor Necrosis Factor-alpha
Interleukin-18
Odds Ratio
Confidence Intervals
Antirheumatic Agents
157 Downloads (Pure)

Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis

Loft, N. D., Skov, L., Rasmussen, M. K., Gniadecki, R., Dam, T. N., Brandslund, I., Hoffmann, H. J., Andersen, M. R., Dessau, R. B., Bergmann, A. C., Andersen, N. M., Abildtoft, M. K., Andersen, P. S., Hetland, M. L., Glintborg, B., Bank, S., Vogel, U. & Andersen, V., 1. Feb 2018, In : PLOS ONE. 13, 2, 12 p., e0192010.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
psoriasis
Psoriatic Arthritis
arthritis
Genetic Polymorphisms
Polymorphism
126 Downloads (Pure)

Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, Bojesen, A. B., Sorensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexøe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., Feb 2018, In : B M J Open. 8, 2, 17 p., e018166.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Precision Medicine
Cohort Studies
Prospective Studies
Tumor Necrosis Factor-alpha
Hidradenitis Suppurativa

Pathophysiology-based phenotyping in type 2 diabetes: A clinical classification tool

Stidsen, J. V., Henriksen, J. E., Olsen, M. H., Thomsen, R. W., Nielsen, J. S., Rungby, J., Ulrichsen, S. P., Berencsi, K., Kahlert, J. A., Friborg, S. G., Brandslund, I., Nielsen, A. A., Christiansen, J. S., Sørensen, H. T., Olesen, T. B. & Beck-Nielsen, H., Jul 2018, In : Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 5, 11 p., e3005.

Research output: Contribution to journalJournal articleResearchpeer-review

Medical problems
Type 2 Diabetes Mellitus
Insulin Resistance
Glucocorticoids
Insulin
55 Downloads (Pure)

Personalized laboratory medicine: A patient-centered future approach

Prodan Žitnik, I., Černe, D., Mancini, I., Simi, L., Pazzagli, M., Di Resta, C., Podgornik, H., Repič Lampret, B., Trebušak Podkrajšek, K., Sipeky, C., Van Schaik, R., Brandslund, I., Vermeersch, P., Schwab, M. & Marc, J., 27. Nov 2018, In : Clinical Chemistry and Laboratory Medicine. 56, 12, p. 1981–1991

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Precision Medicine
Medicine
Biostatistics
Cost effectiveness
Restoration
180 Downloads (Pure)

Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort

Gedebjerg, A., Almdal, T. P., Berencsi, K., Rungby, J., Nielsen, J. S., Witte, D. R., Friborg, S., Brandslund, I., Vaag, A., Beck-Nielsen, H., Sørensen, H. T. & Thomsen, R. W., Jan 2018, In : Journal of Diabetes and its Complications. 32, 1, p. 34-40

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Diabetes Complications
Type 2 Diabetes Mellitus
Cross-Sectional Studies
Confidence Intervals
Hypertriglyceridemia

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T. & 31 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Bang, L. E., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, L. F., Brandslund, I., Christensen, C., Jensen, G. B., Jørgensen, M. E., Thuesen, B. H. & CHD Exome+ Consortium, 2018, In : Nature Genetics. 50, 1, p. 26-41

Research output: Contribution to journalJournal articleResearchpeer-review

Energy Metabolism
Body Mass Index
Genome-Wide Association Study
Proteins
Adipocytes
121 Downloads (Pure)

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, Badia, R. M., Udler, M., Leong, A., Kaur, V., Flannick, J., Jørgensen, T., Linneberg, A., Jørgensen, M. E., Witte, D. R., Christensen, C., Brandslund, I., Appel, E. V., Scott, R. A., Luan, J., Langenberg, C., Wareham, N. J., Pedersen, O., Zorzano, A., Florez, J. C., Hansen, T., Ferrer, J., Mercader, J. M. & Torrents, D., 1. Dec 2018, In : Nature Communications. 9, 1, 14 p., 321.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Medical problems
Type 2 Diabetes Mellitus
genome
Genes
Genome-Wide Association Study
118 Downloads (Pure)

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

ExomeBP Consortium, MAGIC Consortium, GIANT Consortium, Witte, D. R. & Hansen, T., 1. Apr 2018, In : Nature Genetics. 50, 4, p. 559-571

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Type 2 Diabetes Mellitus
Causality
Odds Ratio
54 Downloads (Pure)

Testosterone levels in third trimester in polycystic ovary syndrome: Odense Child Cohort

Glintborg, D., Jensen, R. C., Bentsen, K., Schmedes, A. V., Brandslund, I., Kyhl, H. B., Bilenberg, N. & Andersen, M. S., 1. Oct 2018, In : The Journal of clinical endocrinology and metabolism. 103, 10, p. 3819–3827

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Polycystic Ovary Syndrome
Third Pregnancy Trimester
Testosterone
Sex Hormone-Binding Globulin
Pregnant Women
2017

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning, A. K., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S. B., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M. J., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S. M., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E-S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J. C. N., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G. R., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 2017, In : Diabetes. 66, 7, p. 2019-2032

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Type 2 Diabetes Mellitus
Fasting
Insulin
Exome
Population

Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, T., Pedersen, O., Christensen, C. K., Torp-Pedersen, C., Gerds, T. A., Brandslund, I., Mandrup-Poulsen, T. & Poulsen, H. E., 2017, In : Diabetes Care. 40, 2, p. 1771-1778

Research output: Contribution to journalJournal articleResearchpeer-review

Type 2 Diabetes Mellitus
Cohort Studies
Prospective Studies
RNA
8-hydroxyguanosine
75 Downloads (Pure)

Exome-wide association study of plasma lipids in >300,000 individuals

Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Di Angelantonio, E., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 31 others, Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y-D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A., Dubé, M-P., Ebeling, T., Eiriksdottir, G., Hansen, T., Jensen, G. B., Jørgensen, M. E. & Charge Diabetes Working Group, 2017, In : Nature Genetics. 49, p. 1758–1766

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Exome
Lipids
Type 2 Diabetes Mellitus
Coronary Artery Disease
LDL Cholesterol
90 Downloads (Pure)

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus

Gjesing, A. P., Rui, G., Lauenborg, J., Have, C. T., Hollensted, M., Andersson, E., Grarup, N., Sun, J., Quan, S., Brandslund, I., Damm, P., Pedersen, O., Wang, J. & Hansen, T., 2017, In : Journal of the Endocrine Society. 1, 6, p. 681-690

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Gestational Diabetes
Type 2 Diabetes Mellitus
Diet
Glucose Intolerance
Introns
79 Downloads (Pure)

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A-E., Fava, C., Ferreira, T., Herzig, K-H., Giri, A. & 31 others, Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Christensen, C. K., Hansen, T. & Understanding Society Scientific Group, 2017, In : Circulation: Cardiovascular Genetics. 10, 5, e001778.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Meta-Analysis
Exome
Genome-Wide Association Study
150 Downloads (Pure)

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gómez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G. R., Aben, K. K., Adair, L. S., Alam, D. S., Albrecht, E., Allin, K. H., Allison, M. A., Amouyel, P., Appel, E. V. R., Arveiler, D., Asselbergs, F. W., Auer, P. L., Balkau, B., Banas, B., Bang, L. E., Benn, M., Bergmann, S., Brandslund, I., Christensen, C., Hansen, T., Jensen, G. B., Jørgensen, M. E. & EPIC-InterAct Consortium, 9. Feb 2017, In : Nature. 542, 7640, p. 186-190

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Alleles
Insulin-Like Growth Factor Binding Protein 4
Pregnancy-Associated Plasma Protein-A
Multifactorial Inheritance
Genome-Wide Association Study

Rhodopsin in plasma from patients with diabetic retinopathy - development and validation of digital ELISA by Single Molecule Array (Simoa) technology

Petersen, E. R. B., Olsen, D. A., Christensen, H., Hansen, S. B., Christensen, C. & Brandslund, I., 2017, In : Journal of Immunological Methods. 446, p. 60-69

Research output: Contribution to journalJournal articleResearchpeer-review

Rhodopsin
Diabetic Retinopathy
Western World
Young Adult
108 Downloads (Pure)

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason, F., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., 2017, In : Scientific Data. 4, 20 p., 170179.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Diabetes
Medical problems
chronic illness
statistics
Statistics

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

CHARGE Glycemic-T2D Working Group, & CHARGE Blood Pressure Working Group, 2017, In : Journal of the American Society of Nephrology. 28, 3, p. 981-994

Research output: Contribution to journalJournal articleResearchpeer-review

Exome
Kidney
ras Guanine Nucleotide Exchange Factors
Rho Guanine Nucleotide Exchange Factors
Cytochrome P-450 CYP1A1

Stability of Biomedical Components in Blood Samples Transported by Tempus600/Sysmex GLP Robot Reception System

Bøgh Andersen, I., Mogensen, N. & Brandslund, I., Jan 2017, In : The Journal of Applied Laboratory Medicine. 2, 3, p. 376-386

Research output: Contribution to journalJournal articleResearchpeer-review

The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes

Sørensen, A-S., Kjær, L. K., Petersen, K. M., Henriksen, T. M., Cejvanovic, V., Pedersen, O., Hansen, T., Christensen, C. K., Brandslund, I. & Poulsen, H. E., Jul 2017, In : Scandinavian Journal of Clinical & Laboratory Investigation. 77, 4, p. 253-258

Research output: Contribution to journalJournal articleResearchpeer-review

Type 2 Diabetes Mellitus
Smoking
RNA
DNA
Population
2016

Association of parental history of type 2 diabetes with age, lifestyle, anthropometric factors, and clinical severity at type 2 diabetes diagnosis: results from the DD2 study

Svensson, E., Berencsi, K., Sander, S., Mor, A., Rungby, J., Nielsen, J. S., Friborg, S., Brandslund, I., Christiansen, J. S., Vaag, A., Beck-Nielsen, H., Sørensen, H. T. & Thomsen, R. W., 2016, In : Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 3, p. 308-315

Research output: Contribution to journalJournal articleResearchpeer-review

Medical problems
Type 2 Diabetes Mellitus
Confidence Intervals
Abdominal Obesity
Insulin-Secreting Cells

Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

Vestmar, M. A., Andersson, E. A., Christensen, C. R., Hauge, M., Glümer, C., Linneberg, A., Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, O., Holst, B., Grarup, N., Schwartz, T. W. & Hansen, T., 2016, In : Journal of Medical Genetics. 53, 9, p. 616-623

Research output: Contribution to journalJournal articleResearchpeer-review

Arrestin
Population
Ligands
Exome
Adiponectin
161 Downloads (Pure)

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, Iwasaki, M., Fujita, H., Suzuki, K., Danesh, J., Jørgensen, T., Jørgensen, M. E., Witte, D. R., Brandslund, I., Christensen, C., Hansen, T., Mercader, J. M., Flannick, J., Moreno-Macías, H., Burtt, N. P., Zhang, R., Kim, Y. J., Zheng, W., Singh, J. R., Tam, C. H. T., Hirose, H., Maegawa, H., Ito, C., Kaku, K., Watada, H., Tanaka, Y., Tobe, K., Kawamori, R., Kubo, M., Cho, Y. S., Chan, J. C. N., Sanghera, D., Frossard, P., Park, K. S., Shu, X-O., Kim, B-J., Florez, J. C., Tusié-Luna, T., Jia, W., Tai, E. S., Pedersen, O., Saleheen, D., Maeda, S. & Kadowaki, T., 2016, In : Nature Communications. 7, 13 p., 10531.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
genome
Genome-Wide Association Study
loci
Medical problems
Type 2 Diabetes Mellitus
141 Downloads (Pure)

Identification of high-risk patients by human epididymis protein 4 levels during follow-up of ovarian cancer

Dahl Steffensen, K., Waldstrøm, M., Brandslund, I., Lund, B., Sørensen, S. M., Petzold, M. & Jakobsen, A., 2016, In : Oncology Letters. 11, 6, p. 3967-3974

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Epididymis
Ovarian Neoplasms
Proteins
Disease-Free Survival
Multivariate Analysis
114 Downloads (Pure)

Patient pools and the use of "patient means" are valuable tools in quality control illustrated by a bone-specific alkaline phosphatase assay

Hinge, M., Lund, E. D., Brandslund, I., Plesner, T. & Madsen, J. S., 2016, In : Clinical Chemistry and Laboratory Medicine. 54, 3, p. 403-406

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Quality control
Alkaline Phosphatase
Assays
Bone
Biochemistry

Rates of Community-based Antibiotic Prescriptions and Hospital-treated Infections in Individuals With and Without Type 2 Diabetes: A Danish Nationwide Cohort Study, 2004-2012

Mor, A., Berencsi, K., Nielsen, J. S., Rungby, J., Friborg, S., Brandslund, I., Christiansen, J. S., Vaag, A., Beck-Nielsen, H., Sørensen, H. T. & Thomsen, R. W., 2016, In : Clinical Infectious Diseases. 63, 4, p. 501-511

Research output: Contribution to journalJournal articleResearchpeer-review

Type 2 Diabetes Mellitus
Prescriptions
Cohort Studies
Confidence Intervals
Population

The genetic architecture of type 2 diabetes

Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stancáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., 4. Aug 2016, In : Nature. 536, 7614, p. 41-7

Research output: Contribution to journalJournal articleResearchpeer-review

Type 2 Diabetes Mellitus
Genome-Wide Association Study
Exome
Sample Size
Alleles