• Campusvej 55

    5230 Odense M

    Denmark

20142019

Research output per year

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Research Output

2019

A double-headed nucleotide with two cytosines: DNA with condensed information and improved duplex stability

Beck, K., Reslow-Jacobsen, C., Hornum, M., Henriksen, C. & Nielsen, P., 1. Mar 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 5, p. 740-743

Research output: Contribution to journalJournal articleResearchpeer-review

Base-Pairing Properties of Double-Headed Nucleotides

Hornum, M., Stendevad, J., Sharma, P. K., Kumar, P., Nielsen, R. B., Petersen, M. & Nielsen, P., 28. May 2019, In : Chemistry: A European Journal. 25, 30, p. 7387-7395

Research output: Contribution to journalJournal articleResearchpeer-review

Photophysical investigation of two emissive nucleosides exhibiting gigantic stokes shifts

Stendevad, J., Hornum, M., Wüstner, D. & Kongsted, J., 17. Jun 2019, In : Photochemical and Photobiological Sciences. 18, 7, p. 1858-1865 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Rational Design of Nile Red Analogs for Sensing in Membranes

Prioli, S., Reinholdt, P., Hornum, M. & Kongsted, J., 12. Dec 2019, In : Journal of Physical Chemistry B. 123, 49, p. 10424-10432

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Additional Stacking or Base Pairing in the Optimization of Nucleic Acid Recognition

Hornum, M., 31. Jan 2017, Odense: Syddansk Universitet. Det Naturvidenskabelige Fakultet. 336 p.

Research output: Book/anthology/thesis/reportPh.D. thesisResearch

Condensing the information in DNA with double-headed nucleotides

Hornum, M., Sharma, P. K., Reslow-Jacobsen, C., Kumar, P., Petersen, M. & Nielsen, P., 2017, In : Chemical Communications. 53, 70, p. 9717-9720 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Open Access
File
199 Downloads (Pure)

Nucleobase-modified antisense oligonucleotides containing 5-(phenyltriazol)-2′-deoxyuridine nucleotides induce exon-skipping: In vitro

Le, B. T., Hornum, M., Sharma, P. K., Nielsen, P. & Veedu, R. N., 2017, In : RSC Advances. 7, 86, p. 54542-54545

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
175 Downloads (Pure)
2016

Synthesis of new C-5-triazolyl-functionalized thymidine analogs and their ability to engage in aromatic stacking in DNA:DNA and DNA:RNA duplexes

Hornum, M., Djukina, A., Sassnau, A-K. & Nielsen, P., 2016, In : Organic & Biomolecular Chemistry. 19, p. 4436-4447

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
146 Downloads (Pure)

Three new double headed nucleotides with additional nucleobases connected to C-5 of pyrimidines: synthesis, duplex and triplex studies

Kumar, P., Sharma, P. K., Hansen, J., Jedinak, L., Reslow-Jacobsen, C., Hornum, M. & Nielsen, P., 2016, In : Bioorganic & Medicinal Chemistry. 24, 4, p. 742-749

Research output: Contribution to journalJournal articleResearchpeer-review

2015

Increasing the stability of DNA: RNA duplexes by introducing stacking phenyl-substituted pyrazole, furan and triazole moieties in the major groove

Hornum, M., Kumar, P., Podsiadly, P. & Nielsen, P., 2015, In : Journal of Organic Chemistry. 80, 19, p. 9592-9602

Research output: Contribution to journalJournal articleResearchpeer-review

2014

High affinity RNA targeting by oligonucleotides displaying aromatic stacking and amino groups in the major groove. Comparison of triazoles and phenylsubstituents

Kumar, P., Hornum, M., Nielsen, L. J., Enderlin, G., Andersen, N. K., Len, C., Hervé, G., Sartori, G. & Nielsen, P., 2014, In : Journal of Organic Chemistry. 79, 7, p. 2854-2863 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review