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Henrik J. Ditzel is Professor and Head of Research at Cancer and Inflammation Research Unit, Institute of Molecular Medicine, University of Southern Denmark, and Head of Research, Professor of Precision Medicine, and Senior Consultant at the Department of Oncology, Odense University Hospital, and Institute of Clinical Research, University of Southern Denmark. He is also an Adjunct Professor at The Scripps Research Institute, La Jolla, CA, USA and Visiting Professor at Tianjin Medical University Cancer Institute and Hospital in China.

Dr. Ditzel obtained his MD at the University of Odense in 1987. He received his PhD in Cancer immunology in 1992 and defended his medical doctorial thesis (DMSc) at University of Odense in 1999. He has spent 10 years at the prestigious U.S. research institution, The Scripps Research Institute, La Jolla, California, where he held positions as Assistant and Associate Professor and headed several NIH grants. Concurrently with his research effort, Dr. Ditzel completed his clinical training in Clinical Immunology at University of California, Diego (UCSD) Medical Center and became board certified in Histocompatibility and Immunogenetics (ABHI) in 2001. He obtained his California State license in 2002 and served as Associate Clinical professor and Associate clinical Director at the Histocompatibility and Immunogenetics laboratory at UCSD Medical Center.

Since 2003 Dr. Ditzel is Professor at University of Southern Denmark, where he heads a large (20+) translational cancer research group. His primary research interests include breast cancer, precision medicine, drug resistance mechansims, predictive and prognostic biomarker, cancer immunity, cancer stem cells, dissection of the metastasis process, cancer/testis antigens, and targeted therapies. Dr. Ditzel also play a central role in the genomic precision oncology program at Odense University Hospital.

Dr. Ditzel has been a member of NIH study sections and the American Arthritis Foundation Grant Review Board, the Biomedical panel of The Irish Science Foundation and he has reviewed grants from several public and private foundation in the US and Europe. Dr. Ditzel has chaired the Danish Cancer Society Scientific committee (2013-15) and the Danish Cancer Research Foundation (2013-15), and served as a member of these committees for additional 3 years.

He has published more than 160 scientific articles, most regarding cancer and in very prestigious journals, such as Nature Medicine, Nature Immunology, Nature Clinical Practice in Oncology, Nature Communications, Journal Clinical Investigation, JAMA Oncology, and Journal of Experimental Medicine, and given 100+ international invited oral presentations.

He has received several awards and honors, including the Danish Society for Cancer Research Honorary prize in 2011, Research Result of the Year in 2014, Knight of the Order of Dannebrog in 2015, and he was elected member of American Society of Clinical Investigation in 2003.

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Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Cells Chemical Compounds
HIV-1 Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Tumors Chemical Compounds
Libraries Medicine & Life Sciences

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Research Output 1988 2020

ARAP1 is an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma receiving first-line platinum-based antineoplastic therapy

On behalf of Academy of Geriatric Cancer Research (AgeCare), 2. Jan 2020, In : Acta Oncologica. 59, 1, p. 40-47

Research output: Contribution to journalJournal articleResearchpeer-review

Ankyrin Repeat
Platinum
Ovarian Neoplasms
Gene Expression Profiling
Multivariate Analysis
39 Downloads (Pure)

A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence

Brückmann, N. H., Bennedsen, S. N., Duijf, P. H. G., Terp, M. G., Thomassen, M., Larsen, M., Pedersen, C. B., Kruse, T., Alcaraz, N., Ditzel, H. J. & Gjerstorff, M. F., 6. Nov 2019, In : Cell Death & Disease. 10, 11, 12 p., 841.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neoplasms
Epirubicin
Proteins
Cell Aging
Nevus

Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19

Ormhøj, M., Scarfò, I., Cabral, M. L., Bailey, S. R., Lorrey, S. J., Bouffard, A. A., Castano, A. P., Larson, R. C., Riley, L. S., Schmidts, A., Choi, B. D., Andersen, R. S., Cédile, O., Nyvold, C. G., Haaber, J., Gjerstorff, M. F., Ditzel, H. J., Weinstock, D. M., Barington, T., Frigault, M. J. & 1 others, Maus, M. V., 1. Dec 2019, In : Clinical Cancer Research. 25, 23, p. 7046-7057

Research output: Contribution to journalJournal articleResearchpeer-review

Antigen Receptors
B-Cell Lymphoma
T-Cell Antigen Receptor
Lymphoma
CD19 Antigens
3 Downloads (Pure)

Correction: VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR–PI3K–AKT pathway (Oncogene, (2018), 37, 41, (5585-5586), 10.1038/s41388-018-0495-6)

Elias, D., Vever, H., Lænkholm, A. V., Gjerstorff, M. F., Yde, C. W., Lykkesfeldt, A. E. & Ditzel, H. J., 11. Nov 2019, In : Oncogene.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
Publications
Hepatocellular Carcinoma
61 Downloads (Pure)

CYPOR is a novel and independent prognostic biomarker of recurrence-free survival in triple-negative breast cancer patients

Pedersen, M. H., Hood, B. L., Ehmsen, S., Beck, H. C., Conrads, T. P., Bak, M., Ditzel, H. J. & Leth-Larsen, R., 1. Feb 2019, In : International Journal of Cancer. 144, 3, p. 631-640

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
NADPH-Ferrihemoprotein Reductase
Paraffin
Formaldehyde
Lymph Nodes
Regression Analysis

Activities 2005 2019

Oplæg

Henrik Ditzel (Speaker)
17. Jun 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

Foredrag

Henrik Ditzel (Lecturer)
13. Jun 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

American Association of Clinical Oncology (ASCO) Annual Meeting

Henrik Ditzel (Participant)
31. May 20194. Jun 2019

Activity: Attending an eventConference organisation or participation

Foredrag

Henrik Ditzel (Lecturer)
21. Mar 2019

Activity: Talks and presentationsConference presentations

Symposium: Kræftens Bekæmpelse

Henrik Ditzel (Participant)
23. Oct 2017

Activity: Attending an eventConference organisation or participation

Press / Media

Knæk Cancer vil øge ældre patienters overlevelse og livskvalitet

Henrik Ditzel

05/11/2019

1 Media contribution

Press/Media: Press / Media

Blokering af protein stresser brystkræftceller ihjel

Henrik Ditzel

13/11/2018

1 Media contribution

Press/Media: Press / Media

NAVNE I NOTER

Henrik Ditzel

24/10/2018

1 Media contribution

Press/Media: Press / Media

Prizes

Prestigefyldt Kræftforskningspris 2011

Henrik Ditzel (Recipient), 6. May 2011

Prize: Prizes, scholarships, distinctions