Erik Bjerregaard Pedersen

lic.scient.

  • Campusvej 55

    5230 Odense M

    Denmark

1992 …2019
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Personal profile

Curriculum

Curriculum Vitae

Erik Bjerregaard Pedersen


Personal Data: Born 13 July, 1945 in Timring, Denmark

Nationality: Danish

Marital Status:

Married to Inger Line Pedersen, born 25 April, 1946

Children:

Morten Bjerregaard Pedersen, born 20 December, 1969
Klaus Bjerregaard Pedersen, born 14 June, 1972

University Address:

Nucleic Acid Center, Department of Physics and Chemistry,
University of Southern Denmark, Odense, Campusvej 55, DK-5230 Odense M, Denmark
Tel. +45 65 50 25 55 Fax +45 66 15 87 80
Email ebp@chem.sdu.dk
www.sdu.dk/Nat/Chem/STAFF/sci/EbpE.html

Private Address:

Lisas Alle 22,
DK-5230 Odense SV, Denmark
Tel. +45 66172099

General Certificate: 1964, Th. Langs Gymnasium, Silkeborg, Denmark

University Education:

Cand.scient. (M.Sc.) 1970, University of Aarhus, Denmark
Lic.scient. (Ph.D.) 1974, University of Aarhus, with Lektor
S.-O. Lawesson as supervisor

Positions Held:

1970-1972, Kandidatstipendiat (Research Assistant) and
1972-1974, Seniorstipendiat (Senior Research Assistant) at Department of Chemistry, University of Aarhus, Denmark
1974, Postdoc at Professor U. Schöllkopf at Universität Göttingen, Germany
1974 - , Lektor (Associate Professor) at Department of Physics and Chemistry, University of Southern Denmark – Odense

Awards

2008  “Industrial Prize”  The Danish Academy of Natural Sciences
2011  "NAC Research Award"  Nucleic Acid Centre, University of Southern Denmark

Present Research: Modified oligonucleotides and DNA drugs

Publications: More than.300 publications in peer-reviewed journals


Patents:

Eur. Pat. Appl. (1985), 49 pp. EP 155911
PCT Int. Appl. (2003), 313 pp. WO 2003051901
PCT Int. Appl. (2003), 264 pp. WO 2003052132
PCT Int. Appl. (2003), 274 pp. WO 2003052133
PCT Int. Appl. (2003), 264 pp. WO 2003052134
PCT Int. Appl. (2003), 65 pp. WO 2003057677
PCT Int. Appl. (2005), 31 pp. WO 2005083084
PCT Int. Appl. (2006), 54pp. WO 2006125447
PCT Int. Appl. (2008), 52pp. WO 2008067825


Reviews:

Pedersen, O. S.; Pedersen, E. B. Non-nucleoside reverse transcriptase inhibitors. The NNRTI boom. Antiviral Chem. Chemother. 10, 285-314 (1999).

Pedersen, O. S.; Pedersen, E. B. The flourishing syntheses of non-nucleoside reverse transcriptase inhibitors (NNRTIs). Synthesis 2000, 479-495.

Filichev, V.V.; Pedersen, E.B. DNA–Conjugated Organic Chromophores in DNA Stacking Interactions. Wiley Encyclopedea of Chemical Biology 2008, 1-28, John Wiley & Sons, Inc. T. P. Begley (Author). DOI: 10.1002/9780470048672.wecb654



Major Projects:

Enreca 1992-2005. Research capacity building on hepatitis drug discovery in Egypt. (18.8 mio. DKK)
Danish Chemistry Programme 1997-2001. Estalishment of medicinal Chemistry in Odense. (3.5 mio. DKK)
Participating in Nucleic Acid Center under Danish National Research Foundation. 2001-2011
EU project on microbicides (SHIVA) 2004-2009 (593,730 EUR)
EU Madame Curie training centre on Nucleic Acid Based Drug Design (NAC-DRUG) 2004-2008 (1.65 mio. EUR)
PhD School NAC-DRUG 2005-2011 ( 3 grants, 3.62 mio DKK)

Administration:

1981-1986 and 1993-1995, member of the board at Department of Chemistry
1983-1985, vice-chairman and 1985-1986 chairman of Department of Chemistry
1985-1989 Member of the board of Section of Organic Chemistry and
1996-1998 member of the board of The Danish Chemical Society;
1989-1992, member of the Faculty Council of Science
2003-2004 Member of Fagligt Forum, STVF
2005-2007 Member of Academic Council, Faculty of Science, SDU
2006- Research Leader for the section of Synthesis and Medicinal Chemistry including NMR, MS and pharmacy at Department of Physics and Chemistry.

Teaching:

Biomolecular Chemistry (Lectures in chemistry)
Organic Chemical Separation (Laboratory course)
Physical Organic Chemistry (Lectures)

Research areas

Synthesis of nucleic acids (DNA/RNA)

http://www1.sdu.dk/Nat/Chem/staff/sci/Intercalating%20Nucleic%20Acids%20Chemistry2.pdf

 

 Synthesis of new agents against HIV

http://www.nac.sdu.dk/Anti-HIV%20Drugs.pdf

Research information

Synthesis of nucleic acids (DNA/RNA) 

http://www1.sdu.dk/Nat/Chem/staff/sci/Intercalating%20Nucleic%20Acids%20Chemistry2.pdf

Synthesis of new agents against HIV 

http://www.nac.sdu.dk/Anti-HIV%20Drugs.pdf

Research areas

  • Chemistry
  • Bioorganic chemistry
  • DNA
  • Carbohydrates
  • Pharmaceuticals
  • Nucleic acids
  • Organic chemistry

Fingerprint Dive into the research topics where Erik Bjerregaard Pedersen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Nucleic Acids Chemical Compounds
Oligonucleotides Chemical Compounds
Thermodynamic stability Chemical Compounds
HIV-1 Medicine & Life Sciences
DNA Chemical Compounds
Monomers Chemical Compounds
Intercalating Agents Chemical Compounds
Nucleosides Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1992 2019

Intercalating Agents
Quinoxalines
Oligonucleotides
Monomers
Amines

Liposomes Decorated with G-Quadruplex Decoy Oligonucleotides: Their Nanoparticle Delivery and Efficient Bioactivity in Pancreatic Cancer Cells

Pedersen, E. B., Vogel, S. & Xodo, L. E., 2019, p. 69-71. 2 p.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearch

Open Access

Asymmetric Synthesis of Potential Precursors of the HIV Drug MC1220 and Its Analogues by Hydrogenation of (1-Arylvinyl)pyrimidines

Loksha, Y. M. & Pedersen, E. B., 2018, In : Journal of Heterocyclic Chemistry. 55, 6, p. 1352-1357

Research output: Contribution to journalJournal articleResearchpeer-review

Pyrimidines
Hydrogenation
Derivatives
Pharmaceutical Preparations
Bearings (structural)
114 Downloads (Pure)

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

Cogoi, S., Ferino, A., Miglietta, G., Pedersen, E. B. & Xodo, L. E., 2018, In : Nucleic Acids Research. 46, 2, p. 661–676

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
ras Genes
Guanine
Chromatin Immunoprecipitation
Transcription Initiation Site
Epigenomics

Corrigendum to "PNA-COMBO-FISH: From combinatorial probe design in silico to vitality compatible, specific labelling of gene targets in cell nuclei" [Exp. Cell Res. 345 (2016) 51-59]

Müller, P., Rößler, J., Schwarz-Finsterle, J., Pedersen, E. B., Géci, I., Schmitt, E. & Hausmann, M., 15. Jun 2017, In : Experimental Cell Research. 355, 2, p. 194-195 2 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Activities 1976 2019

International Conference on Nanomedicine and Nanobiotechnology 2019

Erik Bjerregaard Pedersen (Participant)
16. Oct 2019

Activity: Attending an eventConference organisation or participation

A contribution from organic chemistry to produce DNA drugs for cancer therapy

Erik Bjerregaard Pedersen (Guest lecturer)
13. Dec 2018

Activity: Talks and presentationsTalks and presentations in private or public companies

The Egyptian Fourth International Conference in Chemistry

Erik Bjerregaard Pedersen (Participant)
11. Dec 201814. Dec 2018

Activity: Attending an eventConference organisation or participation

Alexandria University (External organisation)

Erik Bjerregaard Pedersen (Member)
29. Oct 2017

Activity: MembershipMembership of review committee

28th International Conference on Antiviral Research

Erik Bjerregaard Pedersen (Participant)
11. May 201514. May 2015

Activity: Attending an eventConference organisation or participation

Projects 1998 2019

Novartis - CIBA-GEIGY

Pedersen, E. B.

01/01/199831/12/2012

Project: Research

Novartis - CIBA-GEIGY

Pedersen, E. B.

01/01/199830/09/2019

Project: Research

Tina Holding Aps - Oligoer af TINA-typen

Pedersen, E. B.

01/10/200730/09/2019

Project: Research

Press / Media

Prizes

NAC Research Award

Erik Bjerregaard Pedersen (Recipient), 16. Jun 2011

Prize: Prizes, scholarships, distinctions

Industripris 2008

Erik Bjerregaard Pedersen (Recipient), 5. Dec 2008

Prize: Prizes, scholarships, distinctions