20032020

Research output per year

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Research Output

2020

A Simple and Direct Assay for Monitoring Fatty Acid Synthase Activity and Product-Specificity by High-Resolution Mass Spectrometry

Topolska, M., Martínez-Montañés, F. & Ejsing, C. S., 2020, In : Biomolecules. 10, 1, 118.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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1 Downloads (Pure)

LAMTOR/Ragulator regulates lipid metabolism in macrophages and foam cell differentiation

Lamberti, G., De Smet, C. H., Angelova, M., Kremser, L., Taub, N., Herrmann, C., Hess, M. W., Rainer, J., Tancevski, I., Schweigreiter, R., Kofler, R., Schmiedinger, T., Vietor, I., Trajanoski, Z., Ejsing, C. S., Lindner, H. H., Huber, L. A. & Stasyk, T., Jan 2020, In : FEBS letters. 594, 1, p. 31-42

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
14 Downloads (Pure)

LipidCreator workbench to probe the lipidomic landscape

Peng, B., Kopczynski, D., Pratt, B. S., Ejsing, C. S., Burla, B., Hermansson, M., Benke, P. I., Tan, S. H., Chan, M. Y., Torta, F., Schwudke, D., Meckelmann, S. W., Coman, C., Schmitz, O. J., MacLean, B., Manke, M. C., Borst, O., Wenk, M. R., Hoffmann, N. & Ahrends, R., 2020, In : Nature Communications. 11, 2057.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
14 Downloads (Pure)
2019

Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis

Wenning, L., Ejsing, C. S., David, F., Sprenger, R. R., Nielsen, J. & Siewers, V., 11. Mar 2019, In : Microbial Cell Factories. 18, 1, 49.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
132 Downloads (Pure)

Lipidomics needs more standardization

Lipidomics Standards Initiative Consortium, 1. Aug 2019, In : Nature Metabolism. 1, 8, p. 745-747 3 p.

Research output: Contribution to journalComment/debateResearchpeer-review

MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes

Freyre, C. A. C., Rauher, P. C., Ejsing, C. S. & Klemm, R. W., 5. Dec 2019, In : Molecular Cell. 76, 5, p. 811-825

Research output: Contribution to journalJournal articleResearchpeer-review

Quantification of Cholesterol and Cholesteryl Ester by Direct Flow Injection High-Resolution Fourier Transform Mass Spectrometry Utilizing Species-Specific Response Factors

Höring, M., Ejsing, C. S., Hermansson, M. & Liebisch, G., 2019, In : Analytical Chemistry. 91, 5, p. 3459–3466

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
66 Downloads (Pure)
2018

Automated, parallel mass spectrometry imaging and structural identification of lipids

Ellis, S. R., Paine, M. R. L., Eijkel, G. B., Pauling, J. K., Husen, P., Jervelund, M. W., Hermansson, M., Ejsing, C. S. & Heeren, R. M. A., 2018, In : Nature Methods. 15, 7, p. 515-518

Research output: Contribution to journalLetterResearchpeer-review

Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties

Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Rexen Ulven, E., Milligan, G. & Ulven, T., 8. Nov 2018, In : Journal of Medicinal Chemistry. 61, 21, p. 9534-9550

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
181 Downloads (Pure)

Lipid droplet consumption is functionally coupled to vacuole homeostasis independent of lipophagy

Ouahoud, S., Fiet, M. D., Martínez-Montañés, F., Ejsing, C. S., Kuss, O., Roden, M. & Markgraf, D. F., 11. Jun 2018, In : Journal of Cell Science. 131, 15 p., jcs213876 .

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
199 Downloads (Pure)

Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts

Berzina, Z., Solanko, L. M., Mehadi, A. S., Jensen, M. L. V., Lund, F. W., Modzel, M., Szomek, M., Solanko, K. A., Dupont, A., Nielsen, G. K., Heegaard, C. W., Ejsing, C. S. & Wüstner, D., 2018, In : Chemistry and Physics of Lipids. 213, p. 48-61

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
183 Downloads (Pure)

Regulation of lipid droplets by metabolically controlled Ldo isoforms: Report

Teixeira, V., Johnsen, L., Martínez-Montañés, F., Grippa, A., Buxó, L., Idrissi, F-Z., Ejsing, C. S. & Carvalho, P., 2. Jan 2018, In : The Journal of Cell Biology. 217, 1, p. 127-138

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
138 Downloads (Pure)

Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

Wang, S., Idrissi, F. Z., Hermansson, M., Grippa, A., Ejsing, C. S. & Carvalho, P., 2018, In : Nature Communications. 9, 1, p. 1-12 2939.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
167 Downloads (Pure)

Total Fatty Acid Analysis of Human Blood Samples in One Minute by High-Resolution Mass Spectrometry

Gallego, S. F., Hermansson, M., Liebisch, G., Hodson, L. & Ejsing, C. S., 27. Dec 2018, In : Biomolecules. 9, 1, p. 1-16 7.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
148 Downloads (Pure)
2017

Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism

Kory, N., Grond, S., Kamat, S. S., Li, Z., Krahmer, N., Chitraju, C., Zhou, P., Fröhlich, F., Semova, I., Ejsing, C., Zechner, R., Cravatt, B. F., Farese, R. V. & Walther, T. C., Jan 2017, In : Journal of Lipid Research. 58, 1, p. 226-235

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
201 Downloads (Pure)

Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans

Harvald, E. B., Sprenger, R. R., Dall, K. B., Ejsing, C. S., Nielsen, R., Mandrup, S., Murillo, A. B., Larance, M., Gartner, A., Lamond, A. I. & Færgeman, N. J., 2017, In : Cell Systems. 5, 1, p. 38-52.e4

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
181 Downloads (Pure)

Pex35 is a regulator of peroxisome abundance

Yofe, I., Soliman, K., Chuartzman, S. G., Morgan, B., Weill, U., Yifrach, E., Dick, T. P., Cooper, S. J., Ejsing, C. S., Schuldiner, M., Zalckvar, E. & Thoms, S., 3. Jan 2017, In : Journal of Cell Science. 130, p. 791-804

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
171 Downloads (Pure)

Proposal for a common nomenclature for fragment ions in mass spectra of lipids

Pauling, J. K., Hermansson, M., Hartler, J., Christiansen, K., Gallego, S. F., Peng, B., Ahrends, R. & Ejsing, C. S., 2017, In : PLOS ONE. 12, 11, 21 p., e0188394.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
269 Downloads (Pure)

Quantitative lipidomics reveals age-dependent perturbations of whole-body lipid metabolism in ACBP deficient mice

Gallego, S. F., Sprenger, R. R., Neess, D., Pauling, J. K., Færgeman, N. J. & Ejsing, C. S., Feb 2017, In : B B A - Molecular and Cell Biology of Lipids. 1862, 2, p. 145-155

Research output: Contribution to journalJournal articleResearchpeer-review

Reporting of lipidomics data should be standardized

Liebisch, G., Ekroos, K., Hermansson, M. & Ejsing, C. S., 2017, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 8, p. 747-751

Research output: Contribution to journalJournal articleResearchpeer-review

2016

Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area and Robust in Vivo Efficacy

Hansen, S. V. F., Christiansen, E., Urban, C., Hudson, B. D., Stocker, C. J., Due-Hansen, M. E., Wargent, E. T., Shimpukade, B., Almeida, R., Ejsing, C. S., Cawthorne, M. A., Kassack, M. U., Milligan, G. & Ulven, T., 1. Mar 2016, In : Journal of Medicinal Chemistry. 59, 6, p. 2841-2846

Research output: Contribution to journalJournal articleResearchpeer-review

Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae

Mallela, S. K., Almeida, R., Ejsing, C. S. & Conzelmann, A., 2016, In : P L o S One. 11, 1, p. e0145831 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
150 Downloads (Pure)

Homeoviscous adaptation and the regulation of membrane lipids

Ernst, R., Ejsing, C. S. & Antonny, B., 4. Dec 2016, In : Journal of Molecular Biology. 428, 24 Part A, p. 4776-4791

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
200 Downloads (Pure)

Lipid informatics: From a mass spectrum to interactomics

Ejsing, C. S., Husen, P. J. & Tarasov, K., 2016, Lipidomics, technologies and applications. Ekroos, K. (ed.). Wiley, p. 147-174

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Mga2 transcription factor regulates an oxygen-responsive lipid homeostasis pathway in fission yeast

Burr, R., Stewart, E. V., Shao, W., Zhao, S., Hannibal-Bach, H. K., Ejsing, C. S. & Espenshade, P. J., 3. Jun 2016, In : Journal of Biological Chemistry. 291, 23, p. 12171-12183

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
180 Downloads (Pure)

Seipin is required for converting nascent to mature lipid droplets

Wang, H., Becuwe, M., Housden, B. E., Chitraju, C., Porras, A. J., Graham, M. M., Liu, X. N., Thiam, A. R., Savage, D. B., Agarwal, A. K., Garg, A., Olarte, M-J., Lin, Q., Fröhlich, F., Hannibal-Bach, H. K., Upadhyayula, S., Perrimon, N., Kirchhausen, T., Ejsing, C. S., Walther, T. C. & 1 others, Farese, R. V., 26. Aug 2016, In : eLife. 5, 28 p., e16582.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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414 Downloads (Pure)

Structural characterization of suppressor lipids by high-resolution mass spectrometry

Rovillos, M. J., Pauling, J. K., Hannibal-Bach, H. K., Vionnet, C., Conzelmann, A. & Ejsing, C. S., 30. Oct 2016, In : Rapid Communications in Mass Spectrometry. 30, 20, p. 2215-2227

Research output: Contribution to journalJournal articleResearchpeer-review

2015

Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases

Christiansen, E., Watterson, K. R., Stocker, C. J., Sokol, E., Jenkins, L., Simon, K., Grundmann, M., Petersen, R. K., Wargent, E. T., Hudson, B. D., Kostenis, E., Ejsing, C. S., Cawthorne, M. A., Milligan, G. & Ulven, T., 2015, In : The British Journal of Nutrition. 113, 11, p. 1677-1688 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
201 Downloads (Pure)
Open Access
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252 Downloads (Pure)

Comprehensive lipidome analysis by shotgun lipidomics on a hybrid quadrupole-orbitrap-linear ion trap mass spectrometer

Almeida, R., Pauling, J. K., Sokol, E., Hannibal-Bach, H. K. & Ejsing, C. S., Jan 2015, In : Journal of the American Society for Mass Spectrometry. 26, 1, p. 133-48

Research output: Contribution to journalJournal articleResearchpeer-review

Identification and Annotation of Lipid Species in Metabolomics Studies Need Improvement

Liebisch, G., Ejsing, C. S. & Ekroos, K., 2015, In : Clinical Chemistry. 61, 12, p. 1542-1544

Research output: Contribution to journalJournal articleResearchpeer-review

Modulation of the Lactobacillus acidophilus La-5 lipidome by different growth conditions

Hansen, M-L. R. W., Clausen, A., Ejsing, C. S. & Risbo, J., Oct 2015, In : Microbiology. 161, 10, p. 1990-8

Research output: Contribution to journalJournal articleResearchpeer-review

Quantitative analysis of proteome and lipidome dynamics reveals functional regulation of global lipid metabolism

Casanovas, A., Sprenger, R. R., Tarasov, K., Ruckerbauer, D. E., Hannibal-Bach, H. K., Zanghellini, J., Jensen, O. N. & Ejsing, C. S., 19. Mar 2015, In : Chemistry & Biology. 22, 3, p. 412-25 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Quantitative Profiling of Long-Chain Bases by Mass Tagging and Parallel Reaction Monitoring

Ejsing, C. S., Bilgin, M. & Fabregat, A., 2015, In : PLOS ONE. 10, 12, 17 p., e0144817.

Research output: Contribution to journalJournal articleResearchpeer-review

Quantitative spatial analysis of the mouse brain lipidome by pressurized liquid extraction surface analysis

Almeida, R., Berzina, Z., Christensen, E. A., Baumgart, J., Vogt, J., Nitsch, R. & Ejsing, C. S., 3. Feb 2015, In : Analytical Chemistry. 87, 3, p. 1749-56

Research output: Contribution to journalJournal articleResearchpeer-review

Rom2-dependent phosphorylation of Elo2 controls the abundance of very long chain fatty acids

Olson, D. K., Fröhlich, F., Christiano, R., Hannibal-Bach, H. K., Ejsing, C. S. & Walther, T. C., 2015, In : Journal of Biological Chemistry. 290, p. 4238-4247

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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145 Downloads (Pure)

Saccharomyces cerevisiae depend on vesicular traffic between Golgi and vacuole when Inositolphosphorylceramide synthase Aur1 is inactivated

Voynova, N. S., Roubaty, C., Vazquez, H. M., Mallela, S. K., Ejsing, C. S. & Conzelmann, A., 2. Oct 2015, In : Eukaryotic Cell. 14, 12, p. 1203-1216

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
118 Downloads (Pure)

Structural characterization of ether lipids from the archaeon Sulfolobus islandicus by high-resolution shotgun lipidomics

Jensen, S. M., Brandl, M., Treusch, A. H. & Ejsing, C. S., Mar 2015, In : Journal of Mass Spectrometry. 50, 3, p. 476-487 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

33 Downloads (Pure)

The Effects of Temperature and Growth Phase on the Lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii

Jensen, S. M., Neesgaard, V. L., Skjoldbjerg, S. L. N., Brandl, M., Ejsing, C. S. & Treusch, A. H., 2015, In : Life. 5, 3, p. 1539-66

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
160 Downloads (Pure)

The GARP complex is required for cellular sphingolipid homeostasis

Fröhlich, F., Petit, C., Kory, N., Christiano, R., Hannibal-Bach, H-K., Graham, M., Liu, X., Ejsing, C. S., Farese, R. V. & Walther, T. C., 2015, In : eLife. 4, e08712 .

Research output: Contribution to journalJournal articleResearchpeer-review

2014

An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER

Markgraf, D. F., Klemm, R. W., Junker, M., Hannibal-Bach, H. K., Ejsing, C. S. & Rapoport, T. A., 2014, In : Cell Reports. 6, 1, p. 44-55

Research output: Contribution to journalJournal articleResearchpeer-review

Characterization of yeast mutants lacking alkaline ceramidases YPC1 and YDC1

Voynova, N. S., Mallela, S. K., Vazquez, H. M., Cerantola, V., Sonderegger, M., Knudsen, J., Ejsing, C. S. & Conzelmann, A., 28. May 2014, In : F E M S Yeast Research. 14, 5, p. 776-788

Research output: Contribution to journalJournal articleResearchpeer-review

High-content screening of yeast mutant libraries by shotgun lipidomics

Tarasov, K., Stefanko, A., Casanovas, A., Surma, M. A., Berzina, Z., Hannibal-Bach, H. K., Ekroos, K. & Ejsing, C. S., Jun 2014, In : Chemical Communications. 10, 6, p. 1364-76 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Shotgun lipidomic analysis of chemically sulfated sterols compromises analytical sensitivity: Recommendation for large-scale global lipidome analysis

Casanovas, A., Hannibal-Bach, H. K., Jensen, O. N. & Ejsing, C. S., 2014, In : European Journal of Lipid Science and Technology. 116, 12, p. 1618-1620

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
271 Downloads (Pure)

Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage

Moessinger, C., Klizaite, K., Steinhagen, A., Philippou-Massier, J., Shevchenko, A., Hoch, M., Ejsing, C. S. & Thiele, C., 10. Dec 2014, In : B M C Cell Biology. 15, 1, p. 43

Research output: Contribution to journalJournal articleResearchpeer-review

2013

A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress

Surma, M. A., Klose, C., Peng, D., Shales, M., Mrejen, C., Stefanko, A., Braberg, H., Gordon, D. E., Vorkel, D., Ejsing, C. S., Farese, R., Simons, K., Krogan, N. J. & Ernst, R., 2013, In : Journal of Molecular Cell Biology. 51, 4, p. 519-530

Research output: Contribution to journalJournal articleResearchpeer-review

Analysis of Lipid Experiments (ALEX): A Software Framework for Analysis of High-Resolution Shotgun Lipidomics Data

Husen, P., Tarasov, K., Katafiasz, M., Sokol, E., Vogt, J., Baumgart, J., Nitsch, R., Ekroos, K. & Ejsing, C. S., 2013, In : PLOS ONE. 8, 11, p. e79736

Research output: Contribution to journalJournal articleResearchpeer-review

Characterization of archaeal membrane lipids from sulfolobus islandicus for further enhance the stability of liposomes for oral drug delivery

Jensen, S. M., Ejsing, C. S., Brandl, M. & Treusch, A. H., 16. Sep 2013. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Composition, structure and properties of POPC-triolein mixtures. Evidence of triglyceride domains in phospholipid bilayers

Duelund, L., Vestergaard Jensen, G., Hannibal-Bach, H. K., Ejsing, C. S., Skov Pedersen, J., Inkeri Pakkanen, K. & Ipsen, J. H., 2013, In : BBA General Subjects. 1828, 8, p. 1909-1917

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access