• J.B. Winsløws Vej 9, indgang B, 1. Sal

    5000 Odense C

    Denmark

20022020

Research output per year

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Research Output

2020

Bacille Calmette-Guérin vaccination at birth and differential white blood cell count in infancy. A randomised clinical trial

Jensen, S. K., Jensen, T. M., Birk, N. M., Stensballe, L. G., Benn, C. S., Jensen, K. J., Pryds, O., Jeppesen, D. L. & Nissen, T. N., 4. Mar 2020, In : Vaccine. 38, 11, p. 2449-2455

Research output: Contribution to journalJournal articleResearchpeer-review

BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis

EPIC Consortium, 6. May 2020, In : Science Translational Medicine. 12, 542, eaax4517.

Research output: Contribution to journalJournal articleResearchpeer-review

Cesarean delivery and risk of atopic dermatitis

Skajaa, N., Nissen, T. N., Birk, N. M., Jeppesen, D. L., Thøstesen, L. M. & Benn, C. S., May 2020, In : Allergy. 75, 5, p. 1229-1231

Research output: Contribution to journalJournal articleResearchpeer-review

Defining trained immunity and its role in health and disease

Netea, M. G., Domínguez-Andrés, J., Barreiro, L. B., Chavakis, T., Divangahi, M., Fuchs, E., Joosten, L. A. B., van der Meer, J. W. M., Mhlanga, M. M., Mulder, W. J. M., Riksen, N. P., Schlitzer, A., Schultze, J. L., Stabell Benn, C., Sun, J. C., Xavier, R. J. & Latz, E., 1. Jan 2020, In : Nature Reviews. Immunology.

Research output: Contribution to journalReviewResearchpeer-review

Differential effects of BCG vaccine on immune responses induced by vi polysaccharide typhoid fever vaccination: an explorative randomized trial

Blok, B. A., Arts, R. J. W., van Crevel, R., Aaby, P., Joosten, L. A. B., Benn, C. S. & Netea, M. G., Jun 2020, In : European Journal of Clinical Microbiology and Infectious Diseases. 39, 6, p. 1177-1184

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Hospitalizations for infections by age and sex: register-based study of Danish children 1977–2014

Larsen, J. W. W., Sørensen, A. F., Jensen, A. K. G., Poulsen, A., Gehrt, L., Benn, C. S. & Sørup, S., Feb 2020, In : Infectious Diseases. 52, 2, p. 97-106

Research output: Contribution to journalJournal articleResearchpeer-review

How are children who are delayed in the Childhood Vaccination Programme vaccinated: A nationwide register-based cohort study of Danish children aged 15–24 months and semi-structured interviews with vaccination providers

Pedersen, K. B., Holck, M. E., Jensen, A. K. G., Suppli, C. H., Benn, C. S., Krause, T. G. & Sørup, S., Feb 2020, In : Scandinavian Journal of Public Health. 48, 1, p. 96-105

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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43 Downloads (Pure)

Interacting, Nonspecific, Immunological Effects of Bacille Calmette-Guérin and Tetanus-diphtheria-pertussis Inactivated Polio Vaccinations: An Explorative, Randomized Trial

Blok, B. A., de Bree, L. C. J., Diavatopoulos, D. A., Langereis, J. D., Joosten, L. A. B., Aaby, P., van Crevel, R., Benn, C. S. & Netea, M. G., 16. Jan 2020, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 70, 3, p. 455-463

Research output: Contribution to journalJournal articleResearchpeer-review

Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation

Angelidou, A., Conti, M. G., Diray-Arce, J., Benn, C. S., Shann, F., Netea, M. G., Liu, M., Potluri, L. P., Sanchez-Schmitz, G., Husson, R., Ozonoff, A., Kampmann, B., van Haren, S. D. & Levy, O., 24. Feb 2020, In : Vaccine. 38, 9, p. 2229-2240

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
49 Downloads (Pure)

Maternal Priming: Bacillus Calmette-Guérin (BCG) Vaccine Scarring in Mothers Enhances the Survival of Their Child With a BCG Vaccine Scar

Berendsen, M., Øland, C., Bles, P., Jensen, A. K. G., Kofoed, P-E., Whittle, H., De Bree, C., Netea, M., Martins, C., Benn, C. S. & Aaby, P., 30. Apr 2020, In : Pediatric Infectious Diseases Society. Journal. 9, 2, p. 166-172

Research output: Contribution to journalJournal articleResearchpeer-review

Measles Vaccination in Presence of Measles Antibody May Enhance Child Survival

Benn, C. S., Martins, C. L., Andersen, A., Fisker, A. B., Whittle, H. C. & Aaby, P., 7. Feb 2020, In : Frontiers in Pediatrics. 8, 6 p., 20.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
37 Downloads (Pure)

Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children: A prospective cohort study

Thysen, S. M., Benn, C. S., Gomes, V. F., Rudolf, F., Wejse, C., Roth, A., Kallestrup, P., Aaby, P. & Fisker, A., 28. Feb 2020, In : BMJ Open. 10, 2, 10 p., e035595.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
27 Downloads (Pure)

Seasonal variation in the non-specific effects of BCG vaccination on neonatal mortality: Three randomised controlled trials in Guinea-Bissau

Jensen, K. J., Biering-Sørensen, S., Ursing, J., Kofoed, P. E. L., Aaby, P. & Benn, C. S., 5. Mar 2020, In : BMJ Global Health. 5, 3, 10 p., e001873.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
21 Downloads (Pure)

Stopping live vaccines after disease eradication may increase mortality

Aaby, P. & Benn, C. S., 3. Jan 2020, In : Vaccine. 38, 1, p. 10-14

Research output: Contribution to journalComment/debateCommunication

WHO's rollout of malaria vaccine in Africa: can safety questions be answered after only 24 months?

Aaby, P., Fisker, A. B., Björkman, A. & Benn, C. S., 24. Jan 2020, In : BMJ (Clinical research ed.). 368, 6 p., l6920.

Research output: Contribution to journalJournal articleResearchpeer-review

2019

BCG Vaccination at Birth and Rate of Hospitalization for Infection Until 15 Months of Age in Danish Children: A Randomized Clinical Multicenter Trial

Stensballe, L. G., Ravn, H., Birk, N. M., Kjærgaard, J., Nissen, T. N., Pihl, G. T., Thøstesen, L. M., Greisen, G., Jeppesen, D. L., Kofoed, P-E., Pryds, O., Sørup, S., Aaby, P. & Benn, C. S., Sep 2019, In : Pediatric Infectious Diseases Society. Journal. 8, 3, p. 213-220

Research output: Contribution to journalJournal articleResearchpeer-review

BCG vaccination is associated with reduced malaria prevalence in children under the age of 5 years in sub-Saharan Africa

Berendsen, M. L. T., Van Gijzel, S. W. L., Smits, J., De Mast, Q., Aaby, P., Benn, C. S., Netea, M. G. & Van Der Ven, A. J. A. M., 1. Nov 2019, In : BMJ Global Health. 4, 6, 11 p., e001862.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
72 Downloads (Pure)

Can earlier BCG vaccination reduce early infant mortality? Study protocol for a cluster randomised trial in Guinea-Bissau

Thysen, S. M., Jensen, A. K. G., Rodrigues, A., Borges, I. D. S., Aaby, P., Benn, C. & Fisker, A., 24. Sep 2019, In : BMJ Open. 9, 9, 7 p., e025724.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
109 Downloads (Pure)

Cohort profile: Bandim Health Project's (BHP) rural Health and Demographic Surveillance System (HDSS) - A nationally representative HDSS in Guinea-Bissau

Thysen, S. M., Fernandes, M., Benn, C. S., Aaby, P. & Fisker, A. B., 11. Jun 2019, In : BMJ Open. 9, 6, 8 p., e028775.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
94 Downloads (Pure)

Developing the concept of beneficial non-specific effect of live vaccines with epidemiological studies

Aaby, P. & Benn, C. S., Dec 2019, In : Clinical Microbiology and Infection. 25, 12, p. 1459-1467 9 p.

Research output: Contribution to journalReviewResearchpeer-review

Does India Need a Universal High-Dose Vitamin A Supplementation Program?

Greiner, T., Mason, J., Benn, C. S. & Sachdev, H. P. S., Jun 2019, In : The Indian Journal of Pediatrics. 86, 6, p. 538-541

Research output: Contribution to journalReviewResearchpeer-review

Early BCG Vaccination, Hospitalizations, and Hospital Deaths: Analysis of a Secondary Outcome in 3 Randomized Trials from Guinea-Bissau

Schaltz-Buchholzer, F., Biering-Sørensen, S., Lund, N., Monteiro, I., Umbasse, P., Fisker, A. B., Andersen, A., Rodrigues, A., Aaby, P. & Benn, C. S., 29. Jan 2019, In : The Journal of Infectious Diseases. 219, 4, p. 624-632

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
50 Downloads (Pure)

Early vaccination with BCG-Denmark or BCG-Japan versus BCG-Russia to healthy newborns in Guinea-Bissau: A randomized controlled trial

Schaltz-Buchholzer, F., Bjerregaard-Andersen, M., Øland, C. B., Golding, C., Stjernholm, E. B., Monteiro, I., Aaby, P. & Benn, C. S., 3. Nov 2019, In : Clinical Infectious Diseases. 11 p., ciz1080.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
13 Downloads (Pure)

Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau

Hansen, O. B., Rodrigues, A., Martins, C., Rieckmann, A., Benn, C. S., Aaby, P. & Fisker, A. B., 1. Oct 2019, In : Journal of Tropical Pediatrics. 65, 5, p. 446-456

Research output: Contribution to journalJournal articleResearchpeer-review

Is it time for South Africa to end the routine high-dose vitamin A supplementation programme?

Coutsoudis, A., Sanders, D., Dhansay, M. A., van Stuijvenberg, M. E. & Benn, C. S., 27. Nov 2019, In : S A M J South African Medical Journal. 109, 12, p. 907-910

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
26 Downloads (Pure)

Lessons Learned from the Testing of Neonatal Vitamin A Supplementation

Benn, C. S., Aaby, P. & Fisker, A. B., 21. Feb 2019, In : Nutrients. 11, 2, 449.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
145 Downloads (Pure)

Maternal measles antibodies and their influence on all-cause mortality following measles vaccination: an alternative to measure very low maternal antibody levels

Smits, G., Stabell Benn, C., Whittle, H., van Binnendijk, R., Aaby, P. & van der Klis, F., 2. May 2019, In : Clinical Infectious Diseases. 68, 10, p. 1758-1760

Research output: Contribution to journalJournal articleResearchpeer-review

Measles, mumps and rubella vs diphtheria-tetanus-acellular-pertussis-inactivated-polio-Haemophilus influenzae type b as the most recent vaccine and risk of early 'childhood asthma'

Rieckmann, A., Hærskjold, A., Benn, C. S., Aaby, P., Lange, T. & Sørup, S., 1. Dec 2019, In : International Journal of Epidemiology. 48, 6, p. 2026-2038

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
13 Downloads (Pure)

Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity

Blok, B. A., Jensen, K. J., Aaby, P., Fomsgaard, A., van Crevel, R., Benn, C. S. & Netea, M. G., Mar 2019, In : European Journal of Clinical Microbiology and Infectious Diseases. 38, 3, p. 449–456

Research output: Contribution to journalJournal articleResearchpeer-review

Outcomes of controlled human malaria infection after BCG vaccination

Walk, J., de Bree, L. C. J., Graumans, W., Stoter, R., van Gemert, G. J., van de Vegte-Bolmer, M., Teelen, K., Hermsen, C. C., Arts, R. J. W., Behet, M. C., Keramati, F., Moorlag, S. J. C. F. M., Yang, A. S. P., van Crevel, R., Aaby, P., de Mast, Q., van der Ven, A. J. A. M., Stabell Benn, C., Netea, M. G. & Sauerwein, R. W., 20. Feb 2019, In : Nature Communications. 10, 8 p., 874.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
188 Downloads (Pure)

Phase-out of smallpox vaccination and the female/male HIV-1 prevalence ratio: an ecological study from Guinea-Bissau

Rieckmann, A., Villumsen, M., Hønge, B. L., Sørup, S., Rodrigues, A., Da Silva, Z. J., Whittle, H., Benn, C. & Aaby, P., 1. Oct 2019, In : BMJ Open. 9, 10, 7 p., e031415.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
64 Downloads (Pure)

Smallpox and BCG vaccination in childhood and cutaneous malignant melanoma in Danish adults followed from 18 to 49 years

Rieckmann, A., Meyle, K. D., Rod, N. H., Baker, J. L., Benn, C. S., Aaby, P. & Sørup, S., 16. Oct 2019, In : Vaccine. 37, 44, p. 6730-6736

Research output: Contribution to journalJournal articleResearchpeer-review

The effect of inactivated mycobacterium paratuberculosis vaccine on the response to a heterologous bacterial challenge in pigs

Jensen, K. J., Hansen, M. S., Heegaard, P. M. H., Benn, C. S. & Jungersen, G., 5. Jul 2019, In : Frontiers in Immunology. 10, JULY, 11 p., 1557.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
94 Downloads (Pure)

The importance of randomised vs non-randomised trials

Rieckmann, A. & Benn, C. S., 24. Aug 2019, In : The Lancet. 394, 10199, p. 634 1 p.

Research output: Contribution to journalComment/debateCommunication

2018

Admission and mortality at the main neonatal intensive care unit in Guinea-Bissau

Joergensen, A. S. P., Bjerregaard-Andersen, M., Biering-Sørensen, S., Byberg, S., Camala, L., Martins, C., Rodrigues, A., Aaby, P. & Benn, C. S., 1. Jul 2018, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 112, 7, p. 335-341

Research output: Contribution to journalJournal articleResearchpeer-review

A Two-Center Randomized Trial of an Additional Early Dose of Measles Vaccine: Effects on Mortality and Measles Antibody Levels

Fisker, A. B., Nebie, E., Schoeps, A., Martins, C., Rodrigues, A., Zakane, A., Kagone, M., Byberg, S., Thysen, S. M., Tiendrebeogo, J., Coulibaly, B., Sankoh, O., Becher, H., Whittle, H. C., van der Klis, F. R. M., Benn, C. S., Sie, A., Müller, O. & Aaby, P., 2. May 2018, In : Clinical Infectious Diseases. 66, 10, p. 1573–1580

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
56 Downloads (Pure)

Bacillus Calmette-Guérin-Induced trained immunity is not protective for experimental influenza A/Anhui/1/2013 (H7N9) infection in mice

J. de Bree, L. C., Marijnissen, R. J., Kel, J. M., Huber, S. K. R., Aaby, P., Benn, C. S., Wijnands, M. V. W., Diavatopoulos, D. A., Crevel, R. V., Joosten, L. A. B., Netea, M. G. & Dulos, J., 2018, In : Frontiers in Immunology. 9, APR, 11 p., 869.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
152 Downloads (Pure)

Bacillus Calmette-Guérin vaccination at birth and in vitro cytokine responses to non-specific stimulation. A randomized clinical trial

Nissen, T. N., Birk, N. M., Blok, B. A., Arts, R. J. W., Andersen, A., Kjærgaard, J., Thøstesen, L. M., Hoffmann, T., Jeppesen, D. L., Nielsen, S. D., Kofoed, P-E., Stensballe, L. G., Aaby, P., Ruhwald, M., Netea, M. G., Benn, C. S. & Pryds, O., Jan 2018, In : European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 37, 1, p. 29–41

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

Arts, R. J. W., Moorlag, S. J. C. F. M., Novakovic, B., Li, Y., Wang, S-Y., Oosting, M., Kumar, V., Xavier, R. J., Wijmenga, C., Joosten, L. A. B., Reusken, C. B. E. M., Benn, C. S., Aaby, P., Koopmans, M. P., Stunnenberg, H. G., van Crevel, R. & Netea, M. G., 10. Jan 2018, In : Cell Host & Microbe. 23, 1, p. 89-100.e5

Research output: Contribution to journalJournal articleResearchpeer-review

Begrænset kendskab til effekten af vaccinationer og A-vitamintilskud på børnedødeligheden i Afrika

Translated title of the contribution: Limited knowledge of the effect on child mortality of vaccinations and vitamin A supplementationFisker, A., Marie Thysen, S., Benn, C. S. & Aaby, P., 29. Oct 2018, In : Ugeskrift for Laeger. 180, 22, V06180465.

Research output: Contribution to journalJournal articleResearchpeer-review

Determinants of BCG scarification among children in rural Guinea-Bissau: A prospective cohort study

Funch, K. M., Thysen, S. M., Rodrigues, A., Martins, C. L., Aaby, P., Benn, C. S. & Fisker, A. B., 3. Oct 2018, In : Human Vaccines & Immunotherapeutics. 14, 10, p. 2434-2442

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
170 Downloads (Pure)

Evidence of Increase in Mortality After the Introduction of Diphtheria-Tetanus-Pertussis Vaccine to Children Aged 6-35 Months in Guinea-Bissau: A Time for Reflection?

Aaby, P., Mogensen, S. W., Rodrigues, A. & Benn, C. S., Mar 2018, In : Frontiers in Public Health. 6, 10 p., 79.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
168 Downloads (Pure)

How to evaluate potential non-specific effects of vaccines: the quest for randomized trials or time for triangulation?

Benn, C. S., Fisker, A. B., Rieckmann, A., Jensen, A. K. G. & Aaby, P., May 2018, In : Expert Review of Vaccines. 17, 5, p. 411-420

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
188 Downloads (Pure)

Is the decline in neonatal mortality in northern Ghana, 1996-2012, associated with the decline in the age of BCG vaccination? An ecological study

Welaga, P., Debpuur, C., Aaby, P., Hodgson, A., Azongo, D. K., Benn, C. S. & Oduro, A. R., 14. Dec 2018, In : BMJ Open. 8, 12, 9 p., e023752.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
115 Downloads (Pure)

National Immunization Campaigns with Oral Polio Vaccine Reduce All-Cause Mortality: A Natural Experiment within Seven Randomized Trials

Andersen, A., Fisker, A. B., Rodrigues, A., Martins, C., Ravn, H., Lund, N., Biering-Sorensen, S., Benn, C. S. & Aaby, P., Feb 2018, In : Frontiers in Public Health. 6, 10 p., 13.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
139 Downloads (Pure)

Neonatal BCG vaccination and atopic dermatitis before 13 months of age: A randomized clinical trial

Thøstesen, L. M., Kjaergaard, J., Pihl, G. T., Birk, N. M., Nissen, T. N., Aaby, P., Jensen, A. K. G., Olesen, A. W., Stensballe, L. G., Jeppesen, D. L., Benn, C. S. & Kofoed, P-E., Feb 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 2, p. 498-504

Research output: Contribution to journalJournal articleResearchpeer-review

Non-specific effects of vaccines: Current evidence and potential implications

de Bree, C. L. C. J., Koeken, V. A. C. M., Joosten, L. A. B., Aaby, P., Benn, C. S., van Crevel, R. & Netea, M. G., Oct 2018, In : Seminars in Immunology. 39, p. 35-43

Research output: Contribution to journalReviewResearchpeer-review

Randomized Trial of 2 Versus 1 Dose of Measles Vaccine: Effect on Hospital Admission of Children After 9 Months of Age

Brønd, M., Martins, C. L., Byberg, S., Benn, C. S., Whittle, H., Garly, M-L., Aaby, P. & Fisker, A. B., 17. Aug 2018, In : Pediatric Infectious Diseases Society. Journal. 7, 3, p. 226–233

Research output: Contribution to journalJournal articleResearchpeer-review

Rapid protective effects of early BCG on neonatal mortality among low birth weight boys: Observations from randomized trials

Biering-Sørensen, S., Jensen, K. J., Monterio, I., Ravn, H., Aaby, P. & Benn, C. S., 14. Feb 2018, In : Journal of Infectious Diseases. 217, 5, p. 759–766

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
173 Downloads (Pure)