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Jonathan R. Brewer

PhD

  • Campusvej 55

    5230 Odense M

    Denmark

20042023
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Research Output 2004 2019

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Journal article
2019
104 Downloads (Pure)

Accelerated redevelopment of vocal skills is preceded by lasting reorganization of the song motor circuitry

Vellema, M., Diales Rocha, M., Bascones, S., Zsebők, S., Dreier, J., Leitner, S., Van der Linden, A., Brewer, J. & Gahr, M., 17. May 2019, In : eLife. 8, 26 p., e43194.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Motor Skills
Music
Motor Cortex
Birds
Testosterone

Cross-correlation analysis to quantify relative spatial distributions of fat and protein in super-resolution microscopy images of dairy gels

Glover, Z. J., Bisgaard, A. H., Andersen, U., Povey, M. J., Brewer, J. R. & Simonsen, A. C., Dec 2019, In : Food Hydrocolloids. 97, 11 p., 105225.

Research output: Contribution to journalJournal articleResearchpeer-review

Dairies
Oils and fats
Spatial distribution
Microscopy
microscopy

Label free noninvasive spatially resolved NaCl concentration measurements using Coherent Anti-Stokes Raman Scattering microscopy applied to butter

Jensen, B. B., Glover, Z. J., Pedersen, S. M. M., Andersen, U., Duelund, L. & Brewer, J. R., 1. Nov 2019, In : Food Chemistry. 297, 6 p., 124881.

Research output: Contribution to journalJournal articleResearchpeer-review

Raman spectroscopy
butter
Raman scattering
Labels
Microscopy

Measuring molecular order for lipid membrane phase studies: Linear relationship between Laurdan generalized polarization and deuterium NMR order parameter

Leung, S. S. W., Brewer, J., Bagatolli, L. A. & Thewalt, J. L., 1. Dec 2019, In : Biochimica et Biophysica Acta - Biomembranes. 1861, 12, 8 p., 183053.

Research output: Contribution to journalJournal articleResearchpeer-review

Deuterium
Membrane Lipids
Nuclear magnetic resonance
Polarization
Membranes

Seasonal changes in bacteria and phytoplankton biomass control the condition index of the demosponge Halichondria panicea in temperate Danish waters

Lüskow, F., Riisgård, H. U., Solovyeva, V. & Brewer, J. R., 3. Jan 2019, In : Marine Ecology Progress Series. 608, p. 119-132

Research output: Contribution to journalJournal articleResearchpeer-review

sponge
phytoplankton
bacterium
biomass
bacteria

Strain-Dependent Structural Changes in Major and Minor Ampullate Spider Silk Revealed by Two-Photon Excitation Polarization

Iachina, I. & Brewer, J. R., 10. Jun 2019, In : Biomacromolecules. 20, 6, p. 2384-2391

Research output: Contribution to journalJournal articleResearchpeer-review

Silk
Photons
Polarization
Fibers
Crystalline materials
11 Downloads (Pure)

Super-resolution microscopy and empirically validated autocorrelation image analysis discriminates microstructures of dairy derived gels

Glover, Z. J., Ersch, C., Andersen, U., Holmes, M. J., Povey, M. J., Brewer, J. R. & Simonsen, A. C., 1. May 2019, In : Food Hydrocolloids. 90, p. 62-71

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Dairies
autocorrelation
Autocorrelation
Image analysis
microstructure

The nanoscopic molecular pathway through human skin

Iachina, I., Antonescu, I. E., Dreier, J., Sørensen, J. A. & Brewer, J. R., 1. Jul 2019, In : Biochimica et Biophysica Acta - General Subjects. 1863, 7, p. 1226-1233

Research output: Contribution to journalJournal articleResearchpeer-review

Skin
Lipid Bilayers
Lipid bilayers
Molecules
Skin Absorption
2018
Elastin
Fluorescence microscopy
Fluorescence Microscopy
Collagen
Labels
70 Downloads (Pure)

Dynamic Changes in the Protein Localization in the Nuclear Environment in Pancreatic β-Cell after Brief Glucose Stimulation

Kang, T., Jensen, P., Solovyeva, V., Brewer, J. R. & Larsen, M. R., 6. Apr 2018, In : Journal of Proteome Research. 17, 4, p. 1664–1676

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Nuclear Pore
Glucose
Insulin
Proteins
Transcription
2017

Enzymatic studies on planar supported membranes using a widefield fluorescence LAURDAN Generalized Polarization imaging approach

Brewer, J. R., Thoke, H. S., Stock, R. & Bagatolli, L. A., 2017, In : Biochimica et Biophysica Acta - Biomembranes. 1859, 5, p. 888-895

Research output: Contribution to journalJournal articleResearchpeer-review

Fluorescence
Polarization
Membranes
Imaging techniques
Microscopes

Evidence of proteolipid domain formation in an inner mitochondrial membrane mimicking model

Cheniour, M., Brewer, J. R., Bagatolli, L., Marcillat, O. & Granjon, T., 2017, In : Biochimica et Biophysica Acta - General Subjects. 1861, 5 Part A, p. 969-976

Research output: Contribution to journalJournal articleResearchpeer-review

Mitochondrial Form Creatine Kinase
Proteolipids
Mitochondria
Membranes
Cardiolipins
150 Downloads (Pure)

Fundamental constraints in synchronous muscle limit superfast motor control in vertebrates

Mead, A. F., Osinalde, N., Ørtenblad, N., Nielsen, J., Brewer, J., Vellema, M., Adam, I., Scharff, C., Song, Y., Frandsen, U., Blagoev, B., Kratchmarova, I. & Elemans, C. P., 2017, In : eLife. 6, 20 p., e29425.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Muscle
Vertebrates
Muscles
Skates (Fish)
Actomyosin
114 Downloads (Pure)
Open Access
File
Pericardium
Mechanics
Myography
Adventitia
Elastic Modulus
138 Downloads (Pure)

Mapping Charge Carrier Density in Organic Thin-Film Transistors by Time-Resolved Photoluminescence Lifetime Studies

Leißner, T., Jensen, P. B. W., Liu, Y., Brewer, J. R., Fiutowski, J., Rubahn, H-G. & Kjelstrup-Hansen, J., 2017, In : Organic Electronics. 49, p. 69-75

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Thin film transistors
Charge carriers
Carrier concentration
charge carriers
Photoluminescence

On the gastrophysics of jellyfish preparation

Pedersen, M. T., Brewer, J. R., Duelund, L. & Hansen, P. L., 2017, In : International Journal of Gastronomy and Food Science. 9, p. 34-38

Research output: Contribution to journalJournal articleResearchpeer-review

74 Downloads (Pure)

The diffusion dynamics of PEGylated liposomes in the intact vitreous of the ex vivo porcine eye: A fluorescence correlation spectroscopy and biodistribution study

Eriksen, A. Z., Brewer, J., Andresen, T. L. & Urquhart, A. J., 2017, In : International Journal of Pharmaceutics. 522, 1-2, p. 90-97

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Eye Diseases
Malus
Static Electricity
75 Downloads (Pure)

The impact of interplay between electronic and steric effects on the synthesis and the linear and non-linear optical properties of diketopyrrolopyrrole bearing benzofuran moieties

Purc, A., Koszarna, B., Iachina, I., Friese, D. H., Tasior, M., Sobczyk, K., Pȩdziński, T., Brewer, J. & Gryko, D. T., 2017, In : Organic Chemistry Frontiers. 4, 5, p. 724-736

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Bearings (structural)
Photons
Optical properties
Coloring Agents
Quantum yield
2016

A new approach for a blood-brain barrier model based on phospholipid vesicles: Membrane development and siRNA-loaded nanoparticles permeability

Gomes, M. J., Dreier, J., Brewer, J., Martins, S., Brandl, M. & Sarmento, B., 2016, In : Journal of Membrane Science. 503, p. 8-15

Research output: Contribution to journalJournal articleResearchpeer-review

Biochemical and Bioimaging Evidence of Cholesterol in Acquired Cholesteatoma

Thorsted, B., Bloksgaard, M., Groza, A., Schousboe, P., Færgeman, N. J., Sørensen, J. A., Svane-Knudsen, V. & Brewer, J. R., 15. Apr 2016, In : Annals of Otology, Rhinology and Laryngology. 125, 8, p. 627-633

Research output: Contribution to journalJournal articleResearchpeer-review

Cholesteatoma
Lipids
Skin
Cholesterol Esters
Thin Layer Chromatography
Open Access
Endothelin-1
Nitric Oxide
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Endothelium-Dependent Relaxing Factors
NG-Nitroarginine Methyl Ester
100 Downloads (Pure)

Spatial distribution and activity of Na +/K +-ATPase in lipid bilayer membranes with phase boundaries

Bhartia, T., Cornelius, F., Brewer, J. R., Bagatolli, L., Simonsen, A. C., Ipsen, J. H. & Mouritsen, O. G., 2016, In : BBA Biomembranes. 1858, 6, p. 1390-1399

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
166 Downloads (Pure)

Superresolution and Fluorescence Dynamics Evidence Reveal That Intact Liposomes Do Not Cross the Human Skin Barrier

Dreier, J., Sørensen, J. A. & Brewer, J. R., 2016, In : P L o S One. 11, 1, 15 p., e0146514.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
skin (animal)
Liposomes
Skin
Fluorescence
fluorescence

π-Expanded 1,3-diketones – synthesis, optical properties and application in two-photon polymerization

Nazir, R., Thorsted, B., Balčiūnas, E., Mazur, L., Deperasińska, I., Samoć, M., Brewer, J. R., Farsari, M. & Gryko, D. T., 2016, In : Journal of Materials Chemistry C. 4, 1, p. 167-177

Research output: Contribution to journalJournal articleResearchpeer-review

2015

Elastin organization in pig and cardiovascular disease patients' pericardial resistance arteries

Bloksgaard, M., Leurgans, T., Nissen, I., Jensen, P. S., Hansen, M. L., Brewer, J. R., Bagatolli, L., Marcussen, N., Irmukhamedov, A., Rasmussen, L. M. & De Mey, J. G. R., 2015, In : Journal of Vascular Research. 52, 1, 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Pericardium
Heart Valves
Photons
Fluorescence Microscopy
Research
147 Downloads (Pure)

Enzyme-Free Detection of Mutations in Cancer DNA Using Synthetic Oligonucleotide Probes and Fluorescence Microscopy

Miotke, L., Maity, A., Ji, H., Brewer, J. & Astakhova, K., 2015, In : PLOS ONE. 10, 8, e0136720.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
oligonucleotide probes
Oligonucleotide Probes
Fluorescence microscopy
fluorescence microscopy
Fluorescence Microscopy
83 Downloads (Pure)

Nanostructure induced changes in lifetime and enhanced second-harmonic response of organic-plasmonic hybrids

Leißner, T., Kostiučenko, O., Brewer, J. R., Rubahn, H-G. & Fiutowski, J., 21. Dec 2015, In : Applied Physics Letters. 107, 25, p. 251102-(1-4) 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
microscopy
harmonics
life (durability)
fluorescence
harmonic generations

Preparing giant unilamellar vesicles (GUVs) of complex lipid mixtures on demand: Mixing small unilamellar vesicles of compositionally heterogeneous mixtures

Bhartia, T., Husen, P. J., Brewer, J. R., Bagatolli, L., Hansen, P. L., Ipsen, J. H. & Mouritsen, O. G., 2015, In : B B A - Biomembranes. 1848, 12, p. 3175-3180 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Slow Relaxation of Shape and Orientational Texture in Membrane Gel Domains

Jeppesen, J. C., Solovyeva, V., Brewer, J. R., Johannes, L., Hansen, P. L. & Simonsen, A. C., 2015, In : Langmuir. 31, 46, p. 12699–12707 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

399 Downloads (Pure)

Tight Coupling of Metabolic Oscillations and Intracellular Water Dynamics in Saccharomyces cerevisiae

Thoke, H. S., Tobiesen, A., Brewer, J. R., Hansen, P. L., Stock, R., Olsen, L. F. & Bagatolli, L., 23. Feb 2015, In : PLOS ONE. 10, 2, 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
2014

Effect of detergents on the physico-chemical properties of skin stratum corneum: A two-photon excitation fluorescence microscopy study.

Bloksgaard, M., Brewer, J. R., Pashkovski, E., Ananthapadmanabhan, KP., Sørensen, J. A. & Bagatolli, L., 2014, In : International Journal of Cosmetic Science. 36, 1, p. 39-45

Research output: Contribution to journalJournal articleResearchpeer-review

Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells

Miethling-Graff, R., Rumpker, R., Richter, M., Verano-Braga, T., Kjeldsen, F., Brewer, J. R., Hoyland, J., Rubahn, H-G. & Erdmann, H., 2014, In : Toxicology in Vitro. 28, 7, p. 1280–1289

Research output: Contribution to journalJournal articleResearchpeer-review

Oxidative stress
Intestinal Mucosa
Cytotoxicity
Silver
Particle Size

Insights into the Cellular Response Triggered by Silver Nanoparticles using Quantitative Proteomics

Verano-Braga, T., Miethling-Graff, R., Wojdyla, K. I., Rogowska-Wrzesinska, A., Brewer, J. R., Erdmann, H. & Kjeldsen, F., 2014, In : A C S Nano. 8, 3, p. 2161–2175

Research output: Contribution to journalJournal articleResearchpeer-review

Quadrupolar, emission-tunable pi-expanded 1,4-dihydropyrrolo 3,2-b pyrroles - synthesis and optical properties

Janiga, A., Bednarska, D., Thorsted, B., Brewer, J. & Gryko, D. T., 2014, In : Organic & Biomolecular Chemistry. 12, 18, p. 2874-2881

Research output: Contribution to journalJournal articleResearchpeer-review

Systematic Variation of Gel-Phase Texture in Phospholipid Membranes

Dreier, J., Brewer, J. R. & Simonsen, A. C., 2014, In : Langmuir. 30 , p. 10678−10685

Research output: Contribution to journalJournal articleResearchpeer-review

Tetraaryl-, Pentaaryl-, and Hexaaryl-1,4-dihydropyrrolo 3,2-b pyrroles: Synthesis and Optical Properties

Krzeszewski, M., Thorsted, B., Brewer, J. & Gryko, D. T., 2014, In : Journal of Organic Chemistry. 79, 7, p. 3119-3128

Research output: Contribution to journalJournal articleResearchpeer-review

2013

Hydrophobic mismatch triggering texture defects in membrane gel domains

Dreier, J., Brewer, J. R. & Simonsen, A. C., 2013, In : The Journal of Physical Chemistry Letters. 4, 17, p. 2789-2793

Research output: Contribution to journalJournal articleResearchpeer-review

Gels
Textures
Membranes
Defects
Lipids

Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure

Solanko, L. M., Wüstner, D., Lund, F. W., Brewer, J. R., Midtiby, H., Bittman, R., Eggeling, C., Honigmann, A. & Dekaris, V., 5. Nov 2013, In : Biophysical Journal. 105, 9, p. 2082-2092 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cholesterol
Membranes
Cell membranes
Fluorophores
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene

Single Molecule Applications of Quantum Dots

Rasmussen, T. E., Jauffred, L., Brewer, J. R., Vogel, S., Torbensen, E. R., Lagerholm, B. C., Oddershede, L. & Christensen, E. A., 2013, In : Journal of Modern Physics. 4, p. 27-42

Research output: Contribution to journalJournal articleResearchpeer-review

Semiconductor quantum dots
Molecules
Lipids
Lipid bilayers
Bleaching

Spatially Resolved Two-Color Diffusion Measurements in Human Skin Applied to Transdermal Liposome Penetration

Brewer, J., Bloksgaard, M., Kubiak, J., Sørensen, J. A. & Bagatolli, L. A., 2013, In : Journal of Investigative Dermatology. 133, p. 1260-1268

Research output: Contribution to journalJournal articleResearchpeer-review

Liposomes
Skin
Color
Fluorophores
Spectroscopy

Structural and dynamical aspects of skin studied by multiphoton excitation fluorescence microscopy-based methods.

Bloksgaard, M., Brewer, J. R. & Bagatolli, L., 2013, In : European Journal of Pharmaceutical Sciences. 50, 5, p. 586-594

Research output: Contribution to journalJournal articleResearchpeer-review

Multiphoton Fluorescence Microscopy
Skin
Fluorescence
Protons
Optical Imaging
2012

Escherichia coli Uropathogenesis In Vitro: Invasion, Cellular Escape, and Secondary Infection Analyzed in a Human Bladder Cell Infection Model

Andersen, T. E., Khandige, S., Madelung, M., Brewer, J., Kolmos, H. J. & Møller-Jensen, J., 2012, In : Infection and Immunity. 80, 5, p. 1858-67 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Coinfection
Epithelial Cells
Uropathogenic Escherichia coli
In Vitro Techniques
Epithelium

Multi-Color Single Particle Tracking with Quantum Dots

Christensen, E. A., Brewer, J. R. & Lagerholm, B. C., 2012, In : P L o S One. 7, 11

Research output: Contribution to journalJournal articleResearchpeer-review

Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphate

Stock, R., Brewer, J. R., Wagner, K., Ramos-Cerrillo, B., Duelund, L., Jernshøj, K. D., Olsen, L. F. & Bagatolli, L., 25. Apr 2012, In : PLOS ONE. 7, 4, p. 1-15 (e-36003) 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

ceramides
sphingomyelins
Sphingomyelins
phosphates
Membranes

Structural characterization and lipid composition of acquired cholesteatoma: a comparative study with normal skin

Bloksgaard, M., Svane-Knudsen, V., Sørensen, J. A., Bagatolli, L. & Brewer, J., 2012, In : Otology & Neurotology. 33, 2, p. 177-83 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cholesteatoma
Lipids
Skin
Multiphoton Fluorescence Microscopy
Membrane Lipids

Texture defects in lipid membrane domains

Dreier, J., Brewer, J. R. & Simonsen, A. C., 2012, In : Soft Matter. 8, p. 4894–4904 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

The acyl-CoA binding protein is required for normal epidermal barrier function in mice

Bloksgaard, M., Bek, S., Marcher, A-B., Neess, D., Brewer, J., Hannibal-Bach, H. K., Helledie, T., Fenger, C., Due, M., Berzina, Z., Neubert, R., Chemnitz, J., Finsen, B., Clemmensen, A., Wilbertz, J., Saxtorph, H., Knudsen, J., Bagatolli, L. & Mandrup, S., 2012, In : Journal of Lipid Research. 53, 10, p. 2162-74 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Diazepam Binding Inhibitor
Skin
Diglycerides
Nonesterified Fatty Acids
Sebum

The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety

Iwai, I., Han, H., Hollander, L. D., Svensson, S., Ofverstedt, L-G., Anwar, J., Brewer, J., Mølgaard, M. B., Laloeuf, A., Nosek, D., Masich, S., Bagatolli, L. A., Skoglund, U. & Norlén, L., 2012, In : Journal of Investigative Dermatology. 132, 9, p. 2215-2225 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Ceramides
Skin
Cholesterol
Molecules
Lipids
2011

Biophysical Evaluation of Food Decontamination Effects on Tissue and Bacteria

Andersen, A. Z., Duelund, L., Brewer, J. R., Nielsen, P. K., Birk, T., Garde, K., Kallipolitis, B. H., Krebs, N. & Bagatolli, L., Jan 2011, In : Food Biophysics. 6, p. 170-182 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

food analysis
Decontamination
decontamination
Bacteria
Tissue

Lipid lateral organization on giant unilamellar vesicles containing lipopolysaccharides

Kubiak, J., Brewer, J. R., Hansen, S. & Bagatolli, L., Feb 2011, In : Biophysical Journal. 100, 4, p. 978-986 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

vesicle
lipid
membrane
gel
coexistence