• J.B. Winsløws Vej 25, 2.

    5000 Odense C

    Denmark

19952019
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Personal profile

Research areas

Research areas

Brain-immune interaction - Glial involvement in neurologic disorders - Microglial response and function in Alzheimer’s disease - Microglial response and function in stroke - Molecular and cellular mechanisms of remyelination

Selected presentations

Jubilee-Meeting for Danish Society for Neuroscience and Phd Course, "Inflammatory cytokines in stroke", Copenhagen, November 27, 2009

Society for Neuroscience, Minisymposium on myeloid cells in the brain during health and disease, "Microglial cells as sensors and modulators of brain pathology". Chicago, October 2009

9th European Meeting on Glial Cell Function in Health and Disease, Paris, Microglial renewal in health and disease: "Microglial response to acute and chronic neuropathology". Chair and speaker. Paris, September 2009

Folkeuniversitet, Syddansk Universitet, Hjernen og dens sygdomme, "Alzheimers sygdom -ny viden om en gammel sygdom". Odense, April 2009

Awards

2009: Savværksmester Jeppe Juhl og hustru Ovita Juhls Mindelegat

2007: Torben Fogs og Erik Triers Research Award in Multiple Sclerosis

2006: The Danish Alzheimer Society Research Foundation Award

Selected publications

Drøjdahl N, Nielsen HH, Gardi J, Wree A, Peterson AC, Nyengaard JR, Eyer J, Finsen B (2010) Axonal plasticity elicits long-term changes in oligodendroglia and myelinated fibers. Glia 58:29-42

Lyck L, Dalmau Santamaria I, Pakkenberg B, Chemnitz J, Schrøder HD, Finsen B*, Gundersen HJG (2009) An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling. J Neurosci Meth 182:143-56. *Corresponding author.

Nielsen HH, Ladeby R, Fenger C, Toft-Hansen H, Babcock AA, Owens T, Finsen B (2009) Enhanced microglial clearance of myelin debris in T cell infiltrated central nervous system. J Neuropathol Exp Neurol 68:845-56

Lambertsen KL, Clausen BH, Babcock A, Gregersen R, Fenger C, Nielsen HH, Haugaard LS, Wirenfeldt M, Nielsen M, Dagnaes-Hansen F, Bluethmann H, Færgeman NJ, Meldgaard M, Deierborg T, Finsen B (2009) Microglia protect neurons against ischemia by synthesis of tumor necrosis factor. J Neurosci 29:1319-1330

Dissing-Olesen L, Thaysen-Andersen M, Meldgaard M, Højrup P, Finsen B (2008) The function of the human interferon-beta 1a glycan determined in vivo. J Pharm Exp Ther 326:338-347

Wirenfeldt M, Dissing-Olesen L, Babcock AA, Nielsen M, Meldgaard M, Zimmer J, Azcoitia I, Leslie RGQ, Dagnæs-Hansen F, Finsen B (2007) Population control of resident and immigrating microglia by mitosis and apoptosis. Am J Pathol 171:17-31

Research areas

  • Health and Illness

Fingerprint Dive into the research topics where Bente Finsen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 23 Similar Profiles
Microglia Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Messenger RNA Medicine & Life Sciences
Neocortex Medicine & Life Sciences
Neurons Medicine & Life Sciences
Tumor Necrosis Factor-alpha Medicine & Life Sciences
Oligodendroglia Medicine & Life Sciences
Perforant Pathway Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1995 2019

1 Downloads (Pure)

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Metaxas, A., Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S., Brooks, D. J., Larsen, M. R. & Finsen, B., 31. Oct 2019, In : Scientific Reports. 9, 1, 15 p., 15758.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Alzheimer Disease
Pathology
Tauopathies
Ribosomal RNA
Energy Metabolism
121 Downloads (Pure)

Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Andersson, C. R., Falsig, J., Stavenhagen, J. B., Christensen, S., Kartberg, F., Rosenqvist, N., Finsen, B. & Pedersen, J. T., 15. Mar 2019, In : Scientific Reports. 9, 1, 12 p., 4658.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Fc Receptors
Microglia
RNA Sequence Analysis
tau Proteins
Messenger RNA

Corrigendum to “Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9transgenic mice: Effect of long-term treatment with paroxetine" [Neurobiol Dis. 2017; 104: 50-60].

Olesen, LØ., Sivasaravanaparan, M., Severino, M., Babcock, A. A., Bouzinova, E. V., West, M. J., Wiborg, O. & Finsen, B., Apr 2019, In : Neurobiology of Disease. 124, p. 573

Research output: Contribution to journalComment/debateResearchpeer-review

Paroxetine
Neurons
corrigendum
44 Downloads (Pure)

Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice

Myhre, C. L., Thygesen, C., Villadsen, B., Vollerup, J., Ilkjær, L., Krohn, K. T., Grebing, M., Zhao, S., Khan, A. M., Dissing-Olesen, L., Jensen, M. S., Babcock, A. A. & Finsen, B., 30. Jul 2019, In : Frontiers in cellular neuroscience. 13, 17 p., 308.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Microglia
Messenger RNA
Tumor Necrosis Factor-alpha
Cell Proliferation
Neurons
11 Downloads (Pure)

Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer's disease

Metaxas, A., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M. & Finsen, B., 1. May 2019, In : Alzheimer's Research & Therapy. 11, 1, 38.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Serotonin Plasma Membrane Transport Proteins
Alzheimer Disease
Interleukin-6
Tumor Necrosis Factor-alpha
Serotonin Antagonists

Activities 2010 2019

Innate microglia in Alzheimer's disease

Bente Finsen (Keynote speaker)
15. Nov 2019

Activity: Talks and presentationsGuest lectures, external teaching and course activities at other universities

Lecture on 'Neurobiology of AD',

Bente Finsen (Guest lecturer)
29. Aug 2019

Activity: Talks and presentationsGuest lectures, external teaching and course activities at other universities

Posterpresentation

Bente Finsen (Other)
10. Jul 201913. Jul 2019

Activity: Talks and presentationsConference presentations

1st Immunology and inflammation Conference

Bente Finsen (Keynote speaker)
24. Mar 201926. Mar 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

Perskeptivering af artiklen: ’Nøglen til at fremme myelindannelse er fundet’

Bente Finsen (Lecturer)
30. Jan 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

Press / Media

Das Immunsystem im Fokus

Bente Finsen

25/02/2019

1 Media contribution

Press/Media: Press / Media

Das Immunsystem im Fokus

Bente Finsen

25/02/2019

1 Media contribution

Press/Media: Press / Media

Virker diætbehandling mod multipel sklerose?

Bente Finsen

13/06/2016

1 item of Media coverage

Press/Media: Press / Media

SDU giver millioner til egen forskning

Sergey I. Bozhevolnyi, James W. Vaupel, Jan Stentoft, Erik Albæk, Anne-Marie Mai, Lars Bo Andersen, Trond Ulven, Bente Finsen, John Hallam, Jan Mollenhauer, Charlotte Kroløkke, Susanne Mandrup, Lars Peter Raahave Østerdal & Jakob Kjelstrup-Hansen

05/07/2013

1 item of Media coverage

Press/Media: Press / Media