Research areas

Brain-immune interaction - Glial involvement in neurologic disorders - Microglial response and function in Alzheimer’s disease - Microglial response and function in stroke - Molecular and cellular mechanisms of remyelination

Selected presentations

Jubilee-Meeting for Danish Society for Neuroscience and Phd Course, "Inflammatory cytokines in stroke", Copenhagen, November 27, 2009

Society for Neuroscience, Minisymposium on myeloid cells in the brain during health and disease, "Microglial cells as sensors and modulators of brain pathology". Chicago, October 2009

9th European Meeting on Glial Cell Function in Health and Disease, Paris, Microglial renewal in health and disease: "Microglial response to acute and chronic neuropathology". Chair and speaker. Paris, September 2009

Folkeuniversitet, Syddansk Universitet, Hjernen og dens sygdomme, "Alzheimers sygdom -ny viden om en gammel sygdom". Odense, April 2009

Awards

2009: Savværksmester Jeppe Juhl og hustru Ovita Juhls Mindelegat

2007: Torben Fogs og Erik Triers Research Award in Multiple Sclerosis

2006: The Danish Alzheimer Society Research Foundation Award

Selected publications

Drøjdahl N, Nielsen HH, Gardi J, Wree A, Peterson AC, Nyengaard JR, Eyer J, Finsen B (2010) Axonal plasticity elicits long-term changes in oligodendroglia and myelinated fibers. Glia 58:29-42

Lyck L, Dalmau Santamaria I, Pakkenberg B, Chemnitz J, Schrøder HD, Finsen B*, Gundersen HJG (2009) An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling. J Neurosci Meth 182:143-56. *Corresponding author.

Nielsen HH, Ladeby R, Fenger C, Toft-Hansen H, Babcock AA, Owens T, Finsen B (2009) Enhanced microglial clearance of myelin debris in T cell infiltrated central nervous system. J Neuropathol Exp Neurol 68:845-56

Lambertsen KL, Clausen BH, Babcock A, Gregersen R, Fenger C, Nielsen HH, Haugaard LS, Wirenfeldt M, Nielsen M, Dagnaes-Hansen F, Bluethmann H, Færgeman NJ, Meldgaard M, Deierborg T, Finsen B (2009) Microglia protect neurons against ischemia by synthesis of tumor necrosis factor. J Neurosci 29:1319-1330

Dissing-Olesen L, Thaysen-Andersen M, Meldgaard M, Højrup P, Finsen B (2008) The function of the human interferon-beta 1a glycan determined in vivo. J Pharm Exp Ther 326:338-347

Wirenfeldt M, Dissing-Olesen L, Babcock AA, Nielsen M, Meldgaard M, Zimmer J, Azcoitia I, Leslie RGQ, Dagnæs-Hansen F, Finsen B (2007) Population control of resident and immigrating microglia by mitosis and apoptosis. Am J Pathol 171:17-31