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2020

DDI2 Is a Ubiquitin-Directed Endoprotease Responsible for Cleavage of Transcription Factor NRF1

Dirac-Svejstrup, A. B., Walker, J., Faull, P., Encheva, V., Akimov, V., Puglia, M., Perkins, D., Kümper, S., Hunjan, S. S., Blagoev, B., Snijders, A. P., Powell, D. J. & Svejstrup, J. Q., 6. Sep 2020, In : Molecular Cell.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Kappa- opioid receptor regulates human sperm functions via SPANX-A/D protein family

Urizar-Arenaza, I., Osinalde, N., Akimov, V., Puglia, M., Muñoa-Hoyos, I., Gómez-Giménez, B., Gianzo, M., Ganzabal, T., Blagoev, B., Kratchmarova, I. & Subiran, N., 16. Jun 2020, In : Reproductive Biology.

Research output: Contribution to journalJournal articleResearchpeer-review

Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow-derived stromal stem cells

Barrio-Hernandez, I., Jafari, A., Rigbolt, K. T. G., Hallenborg, P., Sanchez-Quiles, V., Skovrind, I., Akimov, V., Kratchmarova, I., Dengjel, J., Kassem, M. & Blagoev, B., Jan 2020, In : Genome Research. 30, 1, p. 127-137 11 p.

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SPANX-A/D protein subfamily plays a key role in nuclear organisation, metabolism and flagellar motility of human spermatozoa

Urizar-Arenaza, I., Osinalde, N., Akimov, V., Puglia, M., Muñoa-Hoyos, I., Gianzo, M., Rodriguez, J. A., Ganzabal, T., Blagoev, B., Kratchmarova, I. & Subiran, N., 27. Mar 2020, In : Scientific Reports. 10, 9 p., 5625.

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2019

NADH dehydrogenase complex I is overexpressed in incipient metastatic murine colon cancer cells

Marquez, J., Kratchmarova, I., Akimov, V., Unda, F., Ibarretxe, G., Clerigué, A. S., Osinalde, N. & Badiola, I., 1. Feb 2019, In : Oncology Reports. 41, 2, p. 742-752

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Open Access
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Phosphoproteomic and functional analyses reveal sperm-specific protein changes downstream of kappa opioid receptor in human spermatozoa

Urizar-Arenaza, I., Osinalde, N., Akimov, V., Puglia, M., Candenas, L., Pinto, F. M., Muñoa-Hoyos, I., Gianzo, M., Matorras, R., Irazusta, J., Blagoev, B., Subiran, N. & Kratchmarova, I., 15. Mar 2019, In : Molecular and Cellular Proteomics. 18, Suppl 1, p. S118-S131

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2018

Data on mass spectrometry-based proteomics for studying the involvement of CYLD in the ubiquitination events downstream of EGFR activation

Sanchez-Quiles, V., Osinalde, N., Akimov, V., Kratchmarova, I. & Blagoev, B., 1. Jun 2018, In : Data in Brief. 18, p. 1856-1863

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Open Access
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StUbEx PLUS-A Modified Stable Tagged Ubiquitin Exchange System for Peptide Level Purification and In-Depth Mapping of Ubiquitination Sites

Akimov, V., Olsen, L. C. B., Hansen, S. V. F., Barrio-Hernandez, I., Puglia, M., Jensen, S. S., Solov'yov, I. A., Kratchmarova, I. & Blagoev, B., 2018, In : Journal of Proteome Research. 17, 1, p. 296-304

Research output: Contribution to journalJournal articleResearchpeer-review

UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites

Akimov, V., Barrio-Hernandez, I., Hansen, S. V. F., Hallenborg, P., Pedersen, A-K., Bekker-Jensen, D. B., Puglia, M., Christensen, S. D. K., Vanselow, J. T., Nielsen, M. M., Kratchmarova, I., Kelstrup, C. D., Olsen, J. V. & Blagoev, B., 2018, In : Nature Structural and Molecular Biology. 25, 7, p. 631-640

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Characterization of receptor-associated protein complex assembly in interleukin (IL)-2- and IL-15-activated T-cell lines

Osinalde, N., Sánchez-Quiles, V., Akimov, V., Aloria, K., Arizmendi, J. M., Blagoev, B. & Kratchmarova, I., 6. Jan 2017, In : Journal of Proteome Research. 16, 1, p. 106-121

Research output: Contribution to journalJournal articleResearchpeer-review

Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor

Sanchez-Quiles, V., Akimov, V., Osinalde, N., Francavilla, C., Puglia, M., Barrio-Hernandez, I., Kratchmarova, I., Olsen, J. V. & Blagoev, B., 2017, In : Molecular and Cellular Proteomics. 16, 8, p. 1433-1446 14 p.

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2016

Nuclear Phosphoproteomic Screen Uncovers ACLY as Mediator of IL-2-induced Proliferation of CD4+ T lymphocytes

Osinalde, N., Mitxelena, J., Sánchez-Quiles, V., Akimov, V., Aloria, K., Arizmendi, J. M., Zubiaga, A. M., Blagoev, B. & Kratchmarova, I., Jun 2016, In : Molecular and Cellular Proteomics. 15, 6, p. 2076-92 17 p.

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2015

SILAC-based quantification of changes in protein tyrosine phosphorylation induced by Interleukin-2 (IL-2) and IL-15 in T-lymphocytes

Osinalde, N., Sánchez-Quiles, V., Akimov, V., Blagoev, B. & Kratchmarova, I., Dec 2015, In : Data in Brief. 5, p. 53-58

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Open Access
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Simultaneous dissection and comparison of IL-2 and IL-15 signaling pathways by global quantitative phosphoproteomics

Osinalde, N., Sánchez-Quiles, V., Akimov, V., Guerra, B., Blagoev, B. & Kratchmarova, I., 2015, In : Proteomics. 15, 2-3, p. 520-31

Research output: Contribution to journalJournal articleResearchpeer-review

2014

Phosphorylation site dynamics of early T-cell receptor signaling

Chylek, L. A., Akimov, V., Dengjel, J., Rigbolt, K. T. G., Hu, B., Hlavacek, W. S. & Blagoev, B., 2014, In : PLOS ONE. 9, 8, p. e104240

Research output: Contribution to journalJournal articleResearchpeer-review

StUbEx: Stable Tagged Ubiquitin Exchange System for the Global Investigation of Cellular Ubiquitination

Akimov, V., Henningsen, J., Hallenborg, P., Rigbolt, K. T. G., Jensen, S. S., Nielsen, M. M., Kratchmarova, I. & Blagoev, B., 2014, In : Journal of Proteome Research. 13, 9, p. 4192-4204

Research output: Contribution to journalJournal articleResearchpeer-review

2013

JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks

Watanabe, S., Watanabe, K., Akimov, V., Bartkova, J., Blagoev, B., Lukas, J. & Bartek, J., 2013, In : Nature Structural and Molecular Biology. 20, 12, p. 1425-33

Research output: Contribution to journalJournal articleResearchpeer-review

The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

Altmeyer, M. F., Toledo, L., Gudjonsson, T., Grøfte, M., Rask, M-B., Lukas, C., Akimov, V., Blagoev, B., Bartek, J. & Lukas, J., 2013, In : Molecular Cell. 52, 2, p. 206-220

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens

Dengjel, J., Høyer-Hansen, M., Nielsen, M., Eisenberg, T., Harder, L. M., Schandorff, S., Farkas, T., Kirkegaard, T., Becker, A. C., Schroeder, S., Vanselow, K., Lundberg, E., Nielsen, M. M., Kristensen, A. R., Akimov, V., Bunkenborg, J., Madeo, F., Jäättelä, M. & Andersen, J. S., 2012, In : Molecular and Cellular Proteomics. 11, 3, p. M111.014035

Research output: Contribution to journalJournal articleResearchpeer-review

Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation

Hallenborg, P., Feddersen, S., Francoz, S., Murano, I., Sundekilde, U., Petersen, R. K., Akimov, V., Olson, M. V., Lozano, G., Cinti, S., Gjertsen, B. T., Madsen, L., Marine, J-C., Blagoev, B. & Kristiansen, K., 2012, In : Cell Death and Differentiation. 19, 8, p. 1381-9 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2011

Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics

Akimov, V., Rigbolt, K. T. G., Nielsen, M. M. & Blagoev, B., 1. Dec 2011, In : Molecular BioSystems. 7, 12, p. 3223-33 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

Rigbolt, K. T. G., Prokhorova, T. A., Akimov, V., Henningsen, J., Johansen, P. T., Kratchmarova, I., Kassem, M., Mann, M., Olsen, J. V. & Blagoev, B., 2011, In : Science Signaling. 4, 164, p. rs3

Research output: Contribution to journalJournal articleResearchpeer-review