• J.B. Winsløws Vej 9, indgang B, 1. Sal

    5000 Odense C

    Denmark

19982020
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Personal profile

Curriculum

Curriculum Vitae for Jacob v B. Hjelmborg

Professor in Biostatistics, MSc, PhD, in mathematics, specialized in biostatistics with focus on twin and family study methodology. He is national editor of Scandinavian Journal of Statistics, co-lead researcher of the Nordic Twin Cancer Study and responsible for the Analysis of Twin Data Workshop held yearly since 2008 with international participation.

Work address
Epidemiology, Biostatistics, and Biodemography, Dept. of Public Health, Univ. of Southern Denmark, J.B. Winsloews Vej 9B, 5000 Odense C, Denmark
E-mail: jhjelmborg@health.sdu.dk

Education and academic degrees
Ph.D. in Mathematics at the Faculty of Natural Sciences, University of Southern Denmark, 2000
Employment
Professor in Biostatistics at Institute of Public Health (IPH), University of Southern Denmark
(SDU), 2014-
Associate Professor in Biostatistics, IPH, SDU, 2006-2014
Assistant Professor in Biostatistics, IPH, SDU, 2004-2006
Post Doc in Biostatistics, Institute of Public Health, University of Southern Denmark, 2001-2004
Post Doc in Mathematics, Institute of Mathematics, University of Oslo, Norway, 2000-2001
Ph.D. Student, Institute of Mathematics and Computer Science, University of Southern Denmark,
1997-2000
Graduate Student, The Fields Institute of Mathematics, University of Toronto, Canada, 1995-1996

Management and administrative positions
Head of the biostatistics unit, University of Southern Denmark, 2007-
Board member of the Danish Twin Registry, 2006-
National editor of Scandinavian Journal of Statistics, 2015-
Supervision service in biostatistics, University of Southern Denmark, 2003-

Academic memberships
• Danish Society for Theoretical Statistics
• The International Society for Twin Studies

Supervision
Supervisor for more than 20 PhD, MD, MSc and BA students

Funding
• The Nordic Cancer Union (PI, 650.000DKK), NIH National Institute of Public Health (USA) (Key, 5.270.00DKK, Main: Christensen ), Harvard Univ and Ellison Foundation (Key, 133.000DKK), NIH Telomere Dynamics (Key, 3.570.000DKK, Main: Christensen and Aviv), DSF (Key, 7.651.00DKK, Main: Johannesen), Bloch’s legat (with S. Fibiger).

Scientific publications
As of April 2018: 132 peer reviewed publications. H-index: 29 (ISI Web of Science)

Selected Publications
• Genetic influence on human lifespan and longevity By: Hjelmborg, JV; Iachine, I; Skytthe, A; et al. HUMAN GENETICS Volume: 119 Issue: 3 Pages: 312-321 Published: APR 2006

• Familial Risk and Heritability of Cancer Among Twins in Nordic Countries By: Mucci, Lorelei A.; Hjelmborg, Jacob B.; Harris, Jennifer R.; et al. Group Author(s): Nordic Twin Study Canc NorTwinCan JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Volume: 315 Issue: 1 Pages: 68-76 Published: JAN 5 2016

• The Heritability of Prostate Cancer in the Nordic Twin Study of Cancer By: Hjelmborg, Jacob B.; Scheike, Thomas; Holst, Klaus; et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION Volume: 23 Issue: 11 Pages: 2303-2310 Published: NOV 201

• On stability of C*-algebras By: Hjelmborg, JV; Rordam, M JOURNAL OF FUNCTIONAL ANALYSIS Volume: 155 Issue: 1 Pages: 153-170 Published: MAY 10 1998

• Estimation of direct effects for survival data by using the Aalen additive hazards model By: Martinussen, Torben; Vansteelandt, Stijn; Gerster, Mette; et al.JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY Volume: 73 Pages: 773-788 Part: 5 Published: 2011

• Estimating heritability for cause specific mortality based on twin studies By: Scheike, Thomas H.; Holst, Klaus K.; Hjelmborg, Jacob B. LIFETIME DATA ANALYSIS Volume: 20 Issue: 2 Special Issue: Pages: 210-233 Published: APR 2014

• Purely infinite and stable C*-algebras of graphs and dynamical systems By: Hjelmborg, JV ERGODIC THEORY AND DYNAMICAL SYSTEMS Volume: 21 Pages: 1789-1808 Part: 6 Published: DEC 2001

• Paternal age and telomere length in twins: the germ stem cell selection paradigm By: Hjelmborg, Jacob B.; Dalgard, Christine; Mangino, Massimo; et al. AGING CELL Volume: 14 Issue: 4 Pages: 701-703 Published: AUG 2015

• Genetic Analysis of Rare Disorders: Bayesian Estimation of Twin Concordance Rates By: van den Berg, Stephanie M.; Hjelmborg, Jacob vB. BEHAVIOR GENETICS Volume: 42 Issue: 5 Pages: 857-865 Published: SEP 2012

• Svane, AM, Soerensen, M, Lund, J, Tan, Q, Jylhävä, J, Wang, Y, Pedersen, NL, Hägg, S, Debrabant, B, Deary, IJ, Christensen, K, Christiansen, L & Hjelmborg, JB 2018, 'DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins' Genes, bind 9, nr. 2, 78. DOI: 10.3390/genes9020078

Fingerprint Dive into the research topics where Jacob v. B. Hjelmborg is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 49 Similar Profiles
Twin Studies Medicine & Life Sciences
Telomere Medicine & Life Sciences
Dizygotic Twins Medicine & Life Sciences
Population Medicine & Life Sciences
Monozygotic Twins Medicine & Life Sciences
Longitudinal Studies Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Glioma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1998 2019

2 Downloads (Pure)

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies

Mengel-From, J., Svane, A. M., Pertoldi, C., Kristensen, T. N., Loeschcke, V., Skytthe, A., Christensen, K., Lindahl-Jacobsen, R., Hjelmborg, J. & Christiansen, L., 15. Mar 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fruit
Parents
DNA
Maternal Age
Health

A major limitation of the direction of causation model: Non-shared environmental confounding

Hebbelstrup Rye Rasmussen, S., Ludeke, S. & Hjelmborg, J. V. B., 1. Feb 2019, In : Twin Research and Human Genetics. 22, 1, p. 14-26

Research output: Contribution to journalJournal articleResearchpeer-review

Causality
Research Personnel
Direction compound

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers

Skytthe, A., Harris, J. R., Czene, K., Mucci, L., Adami, H-O., Christensen, K., Hjelmborg, J., Holm, N. V., Nilsen, T. S., Kaprio, J. & Pukkala, E., Apr 2019, In : Twin Research and Human Genetics. 22, 2, p. 99-107

Research output: Contribution to journalJournal articleResearchpeer-review

Confidence Intervals
Incidence
Neoplasms
Population
Registries
49 Downloads (Pure)

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Lund, J., Li, S., Baumbach, J., Svane, A. M., Hjelmborg, J. V. B., Christiansen, L., Christensen, K., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 8. Feb 2019, In : Clinical Epigenetics. 11, 8 p., 23.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
DNA Methylation
Genome-Wide Association Study
Survival Analysis
Proportional Hazards Models
Epigenomics
34 Downloads (Pure)

Epigenome-wide association study of leukocyte telomere length

Lee, Y., Sun, D., Ori, A. P. S., Lu, A. T., Seeboth, A., Harris, S. E., Deary, I. J., Marioni, R. E., Soerensen, M., Mengel-From, J., Hjelmborg, J., Christensen, K., Wilson, J. G., Levy, D., Reiner, A. P., Chen, W., Li, S., Harris, J. R., Magnus, P., Aviv, A. & 2 others, Jugessur, A. & Horvath, S., 26. Aug 2019, In : Aging. 11, 16, p. 5876-5894

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Telomere
Epigenomics
Women's Health
DNA Methylation
Circadian Rhythm

Activities 2002 2019

Determinants for MGMT Glioblastoma Treatment Marker

Jacob v. B. Hjelmborg (Keynote speaker)
28 May 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

Medlem af ph.d. bedømmelsesudvalg

Jacob v. B. Hjelmborg (Examiner)
27. May 2019

Activity: ExaminationExternal examination

IAGG-ER 2019 Gothenburg, Sweden

Kaare Christensen (Participant), Jacob v. B. Hjelmborg (Participant), Mette Wod (Participant), Mette Sørensen (Participant), Jacob Krabbe Pedersen (Participant)
23. May 201925. May 2019

Activity: Attending an eventConference organisation or participation

On Biomarker of Aging and Cancer

Jacob v. B. Hjelmborg (Speaker)
23 May 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

Nordic Infrastructure: Researcher perspective

Jacob v. B. Hjelmborg (Keynote speaker)
15. May 2019

Activity: Talks and presentationsTalks and presentations in private or public companies

Projects 2000 2020

NorTwinCan - Nordisk Tvillingstudie af Cancer

Adami, H., Czene, K., Harris, J. R., Hjelmborg, J. V. B., Kaprio, J., Skytthe, A. & Mucci, L. A.

01/01/200001/01/2020

Project: Research