• J.B. Winsløws Vej 9, indgang B, 1. Sal

    5000 Odense C



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Personal profile


Curriculum Vitae for Jacob v B. Hjelmborg

Professor in Biostatistics, MSc, PhD, in mathematics, specialized in biostatistics with focus on twin and family study methodology. He is national editor of Scandinavian Journal of Statistics, co-lead researcher of the Nordic Twin Cancer Study and responsible for the Analysis of Twin Data Workshop held yearly since 2008 with international participation.

Work address
Epidemiology, Biostatistics, and Biodemography, Dept. of Public Health, Univ. of Southern Denmark, J.B. Winsloews Vej 9B, 5000 Odense C, Denmark
E-mail: jhjelmborg@health.sdu.dk

Education and academic degrees
Ph.D. in Mathematics at the Faculty of Natural Sciences, University of Southern Denmark, 2000
Professor in Biostatistics at Institute of Public Health (IPH), University of Southern Denmark
(SDU), 2014-
Associate Professor in Biostatistics, IPH, SDU, 2006-2014
Assistant Professor in Biostatistics, IPH, SDU, 2004-2006
Post Doc in Biostatistics, Institute of Public Health, University of Southern Denmark, 2001-2004
Post Doc in Mathematics, Institute of Mathematics, University of Oslo, Norway, 2000-2001
Ph.D. Student, Institute of Mathematics and Computer Science, University of Southern Denmark,
Graduate Student, The Fields Institute of Mathematics, University of Toronto, Canada, 1995-1996

Management and administrative positions
Head of the biostatistics unit, University of Southern Denmark, 2007-
Board member of the Danish Twin Registry, 2006-
National editor of Scandinavian Journal of Statistics, 2015-
Supervision service in biostatistics, University of Southern Denmark, 2003-

Academic memberships
• Danish Society for Theoretical Statistics
• The International Society for Twin Studies

Supervisor for more than 20 PhD, MD, MSc and BA students

• The Nordic Cancer Union (PI, 650.000DKK), NIH National Institute of Public Health (USA) (Key, 5.270.00DKK, Main: Christensen ), Harvard Univ and Ellison Foundation (Key, 133.000DKK), NIH Telomere Dynamics (Key, 3.570.000DKK, Main: Christensen and Aviv), DSF (Key, 7.651.00DKK, Main: Johannesen), Bloch’s legat (with S. Fibiger).

Scientific publications
As of April 2018: 132 peer reviewed publications. H-index: 29 (ISI Web of Science)

Selected Publications
• Genetic influence on human lifespan and longevity By: Hjelmborg, JV; Iachine, I; Skytthe, A; et al. HUMAN GENETICS Volume: 119 Issue: 3 Pages: 312-321 Published: APR 2006

• Familial Risk and Heritability of Cancer Among Twins in Nordic Countries By: Mucci, Lorelei A.; Hjelmborg, Jacob B.; Harris, Jennifer R.; et al. Group Author(s): Nordic Twin Study Canc NorTwinCan JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Volume: 315 Issue: 1 Pages: 68-76 Published: JAN 5 2016

• The Heritability of Prostate Cancer in the Nordic Twin Study of Cancer By: Hjelmborg, Jacob B.; Scheike, Thomas; Holst, Klaus; et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION Volume: 23 Issue: 11 Pages: 2303-2310 Published: NOV 201

• On stability of C*-algebras By: Hjelmborg, JV; Rordam, M JOURNAL OF FUNCTIONAL ANALYSIS Volume: 155 Issue: 1 Pages: 153-170 Published: MAY 10 1998

• Estimation of direct effects for survival data by using the Aalen additive hazards model By: Martinussen, Torben; Vansteelandt, Stijn; Gerster, Mette; et al.JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY Volume: 73 Pages: 773-788 Part: 5 Published: 2011

• Estimating heritability for cause specific mortality based on twin studies By: Scheike, Thomas H.; Holst, Klaus K.; Hjelmborg, Jacob B. LIFETIME DATA ANALYSIS Volume: 20 Issue: 2 Special Issue: Pages: 210-233 Published: APR 2014

• Purely infinite and stable C*-algebras of graphs and dynamical systems By: Hjelmborg, JV ERGODIC THEORY AND DYNAMICAL SYSTEMS Volume: 21 Pages: 1789-1808 Part: 6 Published: DEC 2001

• Paternal age and telomere length in twins: the germ stem cell selection paradigm By: Hjelmborg, Jacob B.; Dalgard, Christine; Mangino, Massimo; et al. AGING CELL Volume: 14 Issue: 4 Pages: 701-703 Published: AUG 2015

• Genetic Analysis of Rare Disorders: Bayesian Estimation of Twin Concordance Rates By: van den Berg, Stephanie M.; Hjelmborg, Jacob vB. BEHAVIOR GENETICS Volume: 42 Issue: 5 Pages: 857-865 Published: SEP 2012

• Svane, AM, Soerensen, M, Lund, J, Tan, Q, Jylhävä, J, Wang, Y, Pedersen, NL, Hägg, S, Debrabant, B, Deary, IJ, Christensen, K, Christiansen, L & Hjelmborg, JB 2018, 'DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins' Genes, bind 9, nr. 2, 78. DOI: 10.3390/genes9020078

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Research Output

Clonal hematopoiesis in elderly twins: concordance, discordance and mortality

Hansen, J. W., Pedersen, D. A., Larsen, L. A., Husby, S., Clemmensen, S. B., Hjelmborg, J., Favero, F., Weischenfeldt, J., Christensen, K. & Grønbæk, K., 23. Jan 2020, In : Blood. 135, 4, p. 261-268

Research output: Contribution to journalJournal articleResearchpeer-review

  • Single-cell high content imaging parameters predict functional phenotype of cultured human bone marrow stromal stem cells

    Kowal, J. M., Schmal, H., Halekoh, U., Hjelmborg, J. B. & Kassem, M., Feb 2020, In : Stem Cells Translational Medicine. 9, 2, p. 189-202

    Research output: Contribution to journalJournal articleResearchpeer-review

    Open Access
  • 45 Downloads (Pure)

    Survival after cancer for twins aged 70+

    Villumsen, M. D., Christensen, K., Ewertz, M. & Hjelmborg, J. V. B., Jan 2020, Symposium i anvendt statistik 2020. Linde, P. (ed.). p. 17-26

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

    10-year epigenetic change: age-associated CpGs are differentially heritable

    Reynolds, C., Tan, Q., Munoz, E., Jylhava, J., Hjelmborg, J., Christiansen, L., Hagg, S. & Pedersen, N. L., Nov 2019, In : Behavior Genetics. 49, 6, p. 527 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

    Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies

    Mengel-From, J., Svane, A. M., Pertoldi, C., Kristensen, T. N., Loeschcke, V., Skytthe, A., Christensen, K., Lindahl-Jacobsen, R., Hjelmborg, J. & Christiansen, L., 13. Nov 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 12, p. 1853-1860

    Research output: Contribution to journalJournal articleResearchpeer-review

  • 2 Downloads (Pure)


    Scandinavian Journal of Statistics (Journal)

    Jacob von Bornemann Hjelmborg (Editor)

    Activity: Editorial work and peer reviewEditor of research journalResearch

    DMF-DSTS-DSBS Two Day Meeting

    Birgit Debrabant (Participant), Floor Dijkstra Zegers (Participant), Jacob v. B. Hjelmborg (Participant), Martin Dalgaard Villumsen (Participant), Signe Bedsted Clemmensen (Participant), Ulrich Halekoh (Participant), Philip Hougaard (Participant)
    19. Nov 201920. Nov 2019

    Activity: Attending an eventOrganisation or participation in workshops, courses or seminars

    Determinants for MGMT Glioblastoma Treatment Marker

    Jacob v. B. Hjelmborg (Keynote speaker)
    28. May 2019

    Activity: Talks and presentationsTalks and presentations in private or public companies

    Medlem af ph.d. bedømmelsesudvalg

    Jacob v. B. Hjelmborg (Examiner)
    27. May 2019

    Activity: Examination

    IAGG-ER 2019 Gothenburg, Sweden

    Kaare Christensen (Participant), Jacob v. B. Hjelmborg (Participant), Mette Wod (Participant), Mette Sørensen (Participant), Jacob Krabbe Pedersen (Participant)
    23. May 201925. May 2019

    Activity: Attending an eventConference organisation or participation


    NorTwinCan - Nordisk Tvillingstudie af Cancer

    Adami, H., Czene, K., Harris, J. R., Hjelmborg, J. V. B., Kaprio, J., Skytthe, A. & Mucci, L. A.


    Project: Research