Research Output 1979 2019

2019

Angiotensin AT2-receptor induced interleukin-10 attenuates neuromyelitis optica spectrum disorder-like pathology

Khorooshi, R. M. H., Tofte-Hansen, E. U., Tygesen, C., Montañana Rosell, R., Limburg, H. L., Marczynska, J., Asgari, N., Steckelings, M. & Owens, T., 2019, In : Multiple Sclerosis Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

Angiotensin Type 2 Receptor
Neuromyelitis Optica
Interleukin-10
Pathology
Central Nervous System Diseases
14 Downloads (Pure)

Autoimmune diseases associated with Neuromyelitis Optica Spectrum Disorders: A literature review

Shahmohammadi, S., Doosti, R., Shahmohammadi, A., Mohammadianinejad, S. E., Sahraian, M. A., Azimi, A. R., Harirchian, M. H., Asgari, N. & Naser Moghadasi, A., Jan 2019, In : Multiple Sclerosis and Related Disorders. 27, p. 350-363

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Neuromyelitis Optica
Comorbidity
Immune System Diseases
Patient Care Management
Sjogren's Syndrome
59 Downloads (Pure)

Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Olesen, M. N., Soelberg, K., Debrabant, B., Nilsson, A. C., Lillevang, S. T., Grauslund, J., Brandslund, I., Madsen, J. S., Paul, F., Smith, T. J., Jarius, S. & Asgari, N., 11. Mar 2019, In : Journal of Neuroinflammation. 16, 12 p., 59.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Optic Neuritis
Cerebrospinal Fluid
Cohort Studies
Prospective Studies
Intermediate Filaments
77 Downloads (Pure)

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

Wlodarczyk, A., Benmamar-Badel, A., Cédile, O., Nolling Jensen, K., Kramer, I., Elsborg, N. B. & Owens, T., 10. Jan 2019, In : Frontiers in Cellular Neuroscience. 12, 10 p., 523.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Colony-Stimulating Factor Receptors
Macrophage Colony-Stimulating Factor
Microglia
Ligands
Complement Receptors

Disability and Therapeutic Response in Paediatric Neuromyelitis Optica Spectrum Disorder: A Case Series from Iran

Baghbanian, S. M., Sahraian, M. A., Naser Moghadasi, A. & Asgari, N., 2019, In : Iranian journal of child neurology. 13, 3, p. 99-104

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Neuromyelitis Optica
Iran
Pediatrics
Registries
Pharmaceutical Preparations
39 Downloads (Pure)

Epidemiology of neuromyelitis optica spectrum disorder in Denmark (1998-2008, 2007-2014)

Asgari, N., Lillevang, S. T., Skejoe, H. P. B. & Kyvik, K. O., Jul 2019, In : Brain and Behavior. 9, 7, 8 p., e01338.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neuromyelitis Optica
Denmark
Epidemiology
Epidemiologic Studies
Glial Fibrillary Acidic Protein

Mechanism underlying focal demyelination induced by antibody or T cells

Mørch, M., 12. Apr 2019, Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet.

Research output: Book/anthology/thesis/reportPh.D. thesisResearch

41 Downloads (Pure)

Vocal cord paralysis as primary and secondary results of malignancy. A prospective descriptive study

Knudsen, R., Gaunsbaek, M. Q., Schultz, J. H., Nilsson, A. C., Madsen, J. S. & Asgari, N., Apr 2019, In : Laryngoscope Investigative Otolaryngology. 4, 2, p. 241-245

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Vocal Cord Paralysis
Prospective Studies
Neoplasms
Neurologic Examination
Laryngoscopy
2018
92 Downloads (Pure)

A comparison of pediatric and adult neuromyelitis optica spectrum disorders: A review of clinical manifestation, diagnosis, and treatment

Baghbanian, S. M., Asgari, N., Sahraian, M. A. & Moghadasi, A. N., 15. May 2018, In : Journal of the Neurological Sciences. 388, p. 222-231

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Neuromyelitis Optica
Pediatrics
Central Nervous System Diseases
Neuroimaging
Clinical Trials

Cerebrospinal fluid biomarkers of inflammation and neurodegeneration in acute optic neuritis

Olesen, M. N., Soelberg, K., Nilsson, A. C., Jarius, S., Madsen, J. S., Grauslund, J., Smith, T. J., Lillevang, S. T., Brandslund, I., Paul, F. & Asgari, N., 2018.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Epidemiology of neuromyelitis optica spectrum disorder

Asgari, N., Lillevang, S. T., Skejoe, H. P. B., Falah, M., Stenager, E. & Kyvik, K. O., Jun 2018, In : Acta Neurologica Scandinavica. 137, 6, p. 626-627

Research output: Contribution to journalComment/debateResearchpeer-review

67 Downloads (Pure)

Leptomeningeal and Intraparenchymal Blood Barrier Disruption in a MOG-IgG-Positive Patient

Mohseni, S. H., Skejoe, H. P. B., Wuerfel, J., Paul, F., Reindl, M., Jarius, S. & Asgari, N., 2018, In : Case Reports in Neurological Medicine. 2018, 3 p., 1365175.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Gadolinium
Demyelinating Diseases
Central Nervous System
Serum
100 Downloads (Pure)

Magnetic resonance imaging findings at the first episode of acute optic neuritis

Soelberg, K., Skejoe, H. P. B., Grauslund, J., Smith, T. J., Lillevang, S. T., Jarius, S., Wildemann, B., Paul, F. & Asgari, N., Feb 2018, In : Multiple Sclerosis and Related Disorders. 20, p. 30-36

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Optic Neuritis
Optic Nerve
Pathology

Optical Coherence Tomography in Acute Optic Neuritis: A Population-based Study

Specovius, S., Soelberg, K., Zimmermann, H., Grauslund, J., Mehlsen, J. J., Olesen, C., Neve, A. S. B., Paul, F., Brandt, A. U. & Asgari, N., 1. Dec 2018.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Parental ethnicity associated with risk for multiple sclerosis: A population-based incident case–control study in Iran

Abdollahpour, I., Nedjat, S., Mansournia, M. A., Sahraian, M. A. & Asgari, N., Feb 2018, In : Multiple Sclerosis and Related Disorders. 20, p. 100-103

Research output: Contribution to journalJournal articleResearchpeer-review

Iran
Population
Logistic Models
Geography
Epidemiology

Primary progressive multiple sclerosis in Iran: A consensus recommendation for diagnosis and management

Sahraian, M. A., Baghbanian, S. M., Langroodi, H. G., Abolfazli, R., Alaie, S., Asgari, N., Ashtari, F., Ayromlouh, H., Moghadam, N. B., Foroughipour, M., Majdinasab, N., Mohammadianinejad, S. E., Nickseresht, A., Nourian, A., Shahmohammadi, S., Shayegannejad, V. & Torabi, H. R., Nov 2018, In : Multiple Sclerosis and Related Disorders. 26, p. 112-120

Research output: Contribution to journalReviewResearchpeer-review

Racial differences in neuromyelitis optica spectrum disorder

Kim, S-H., Mealy, M. A., Levy, M., Schmidt, F., Ruprecht, K., Paul, F., Ringelstein, M., Aktas, O., Hartung, H-P., Asgari, N., Tsz-Ching, J. L., Siritho, S., Prayoonwiwat, N., Shin, H-J., Hyun, J-W., Han, M., Leite, M. I., Palace, J. & Kim, H. J., Nov 2018, In : Neurology. 91, 22, p. E2089-E2099

Research output: Contribution to journalJournal articleResearchpeer-review

Neuromyelitis Optica
Age of Onset
Immunosuppressive Agents
Republic of Korea
Denmark
97 Downloads (Pure)

Selective localization of IgG from cerebrospinal fluid to brain parenchyma

Mørch, M. T., Forsberg Sørensen, S., Khorooshi, R. M. H., Asgari, N. & Owens, T., 17. Apr 2018, In : Journal of Neuroinflammation. 15, 8 p., 110.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cerebrospinal Fluid
Neuromyelitis Optica
Pathology
Needles
Cisterna Magna
2017
160 Downloads (Pure)

A novel microglial subset plays a key role in myelinogenesis in developing brain

Wlodarczyk, A., Holtman, I., Krueger, M., Yogev, N., Bruttger, J., Khorooshi, R. M. H., Benmamar-Badel, A., de Boer Bergsma, J., Martin, N. A., Karram, K., Kramer, I., Boddeke, E. W. G. M., Waisman, A., Eggen, B. J. L. & Owens, T., 2017, In : E M B O Journal. 36, 22, p. 3292-3308

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Microglia
Brain
Immunotoxins
Macrophages
Neurology

A population-based prospective study of optic neuritis

Soelberg, K., Jarius, S., Skejoe, H. P. B., Engberg, H., Mehlsen, J., Nilsson, A. C., Madsen, J. S., Reindl, M., Wildemann, B., Grauslund, J., Kyvik, K. O., Smith, T. J., Lillevang, S. T., Paul, F., Weinshenker, B. G. & Asgari, N., 2017, In : Multiple sclerosis. 23, 14, p. 1893-1901

Research output: Contribution to journalJournal articleResearchpeer-review

Optic Neuritis
Prospective Studies
Population
Incidence
Neurologic Examination
104 Downloads (Pure)

CCL2 recruits T cells into the brain in a CCR2-independent manner

Cédile, O., Wlodarczyk, A. & Owens, T., 2017, In : A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 11, p. 945–956

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Central Nervous System
CCR4 Receptors
CXCR3 Receptors
Adenoviridae
Flow Cytometry

Comparison of the efficacy of azathioprine and rituximab in neuromyelitis optica spectrum disorder: a randomized clinical trial

Nikoo, Z., Badihian, S., Shaygannejad, V., Asgari, N. & Ashtari, F., 2017, In : Journal of Neurology. 264, 9, p. 2003-2009

Research output: Contribution to journalLetterResearchpeer-review

Neuromyelitis Optica
Randomized Controlled Trials
Age Distribution
Iran
Names

Differential intrathecal inflammatory markers in acute optic neuritis and later conversion to multiple sclerosis

Olesen, M. N., Soelberg, K., Nilsson, A. C., Jarius, S., Madsen, J. S., Grauslund, J., Smith, T. J., Lillevang, S. T., Brandslund, I., Paul, F., Weinshenker, B. G. & Asgari, N., 2017. 1 p.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Optic Neuritis
Cerebrospinal Fluid
Interleukin-10
Interleukin-17
Interleukin-6
142 Downloads (Pure)

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

Berg, C. T., Khorooshi, R. M. H., Asgari, N. & Owens, T., 2017, In : Journal of Neuroinflammation. 14, p. 127-134 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Demyelinating Diseases
Corpus Callosum
Autoimmune Experimental Encephalomyelitis
Pathology
Neuromyelitis Optica
175 Downloads (Pure)

Noninvasive Retinal Markers in Diabetic Retinopathy: Advancing from Bench towards Bedside

Blindbæk, S. L., Torp, T. L., Lundberg, K., Soelberg, K., Vergmann, A. S., Poulsen, C. D., Frydkjær-Olsen, U., Broe, R., Rasmussen, M. L., Wied, J., Lind, M., Vestergaard, A. H., Peto, T. & Grauslund, J., 2017, In : Journal of Diabetes Research. 2017, 10 p., 2562759.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File

Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study

Nordin, A., Akimoto, C., Wuolikainen, A., Alstermark, H., Forsberg, K., Baumann, P., Pinto, S., de Carvalho, M., Hübers, A., Nordin, F., Ludolph, A. C., Weishaupt, J. H., Meyer, T., Grehl, T., Schweikert, K., Weber, M., Burkhardt, C., Neuwirth, C., Holmøy, T., Morita, M. & 9 others, Tysnes, O. B., Benatar, M., Wuu, J., Lange, D. J., Bisgård, C., Asgari, N., Tarvainen, I., Brännström, T. & Andersen, P. M., 2017, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 18, 3-4, p. 256-264

Research output: Contribution to journalJournal articleResearchpeer-review

Alleles
Polymerase Chain Reaction
Age of Onset
Population
Mutation
2016
136 Downloads (Pure)

Aquaporin-4 IgG autoimmune syndrome and immunoreactivity associated with thyroid cancer

Soelberg, K., Larsen, S. R., Mørch, M., Thomassen, M., Brusgaard, K., Paul, F., Smith, T. J., Godballe, C., Grauslund, J., Lillevang, S. T. & Asgari, N., 2016, In : Neurology: Neuroimmunology & Neuroinflammation. 3, 4, 4 p., e252.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Innate Interferons Regulate CNS Inflammation

Dieu, R., Khorooshi, R. M. H., Mariboe, A., Hyre Arpe, M-L. & Owens, T., 29. Sep 2016.

Research output: Contribution to conference without publisher/journalPosterCommunication

Microglia - Role in Immunity

Owens, T., 27. Apr 2016, Development and Phylogeny of the Immune System. Elsevier, Vol. 1. p. 302-308

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Microglia
Macrophages
Amyloid Plaques
Alzheimer Disease
Homeostasis
240 Downloads (Pure)

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

Pache, F., Zimmermann, H., Mikolajczak, J., Schumacher, S., Lacheta, A., Oertel, F. C., Bellmann-Strobl, J., Jarius, S., Wildemann, B., Reindl, M., Waldman, A., Soelberg, K., Asgari, N., Ringelstein, M., Aktas, O., Gross, N., Buttmann, M., Ach, T., Ruprecht, K., Paul, F. & 2 others, Brandt, A. U. & in cooperation with the Neuromyelitis Optica Study Group (NEMOS), 2016, In : Journal of Neuroinflammation. 13, 10 p., 282.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Optic Neuritis
Multicenter Studies
Neuromyelitis Optica
Nerve Fibers
Ganglia
130 Downloads (Pure)

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

in cooperation with the Neuromyelitis Optica Study Group (NEMOS), 2016, In : Journal of Neuroinflammation. 13, 16 p., 279.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Multicenter Studies
Optic Neuritis
Cerebrospinal Fluid
Serum
Neuromyelitis Optica
168 Downloads (Pure)

MOG-IgG in NMO and related disorders: A multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

in cooperation with the Neuromyelitis Optica Study Group (NEMOS), 2016, In : Journal of Neuroinflammation. 13, 45 p., 280.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
118 Downloads (Pure)

MOG-IgG in NMO and related disorders: A multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome

and in cooperation with the Neuromyelitis Optica Study Group (NEMOS), 2016, In : Journal of Neuroinflammation. 13, 23 p., 281.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Protective roles for microglia inneuroinflammation

Wlodarczyk, A., Holtman, I. R., Bruttger, J., Yogev, N., de Boer-Bergsma, J. J., Jensen, K. N., Martin, N. A., Karram, K., Boddeke, E. W. G. M., Waisman, A., Eggen, B. J. L. & Owens, T., 2016, In : Scandinavian Journal of Immunology. 83, 5, p. 369 1 p., O505.

Research output: Contribution to journalConference abstract in journalResearch

Open Access

Signal abnormalities on magnetic resonance imaging in acute optic neuritis. A prospective study

Soelberg, K., Skejoe, H. P. B., Mehlsen, J., Grauslund, J., Paul, F., Smith, T. J., Lillevang, S. T., Weinshenker, B. & Asgari, N., 15. Sep 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes

Juryńczyk, M., Weinshenker, B., Akman-Demir, G., Asgari, N., Barnes, D., Boggild, M., Chaudhuri, A., D'hooghe, M., Evangelou, N., Geraldes, R., Illes, Z., Jacob, A., Kim, H. J., Kleiter, I., Levy, M., Marignier, R., McGuigan, C., Murray, K., Nakashima, I., Pandit, L. & 11 others, Paul, F., Pittock, S., Selmaj, K., de Sèze, J., Siva, A., Tanasescu, R., Vukusic, S., Wingerchuk, D., Wren, D., Leite, I. & Palace, J., 2016, In : Journal of Neurology. 263, 1, p. 140-149

Research output: Contribution to journalLetterResearchpeer-review

Neuromyelitis Optica
Optic Neuritis
Pharmaceutical Preparations

Type I interferon and receptor activator ofnuclear factor Kappa B signaling withinthe central nervous system

Khorooshi, R. M. H., Dieu, R., Hyre Arpe, M-L., Cédile, O., Mørch, M. T., Lienenklaus, S. & Owens, T., 2016, In : Scandinavian Journal of Immunology. 83, 5, p. 348 1 p., O102.

Research output: Contribution to journalConference abstract in journalResearch

2015

Antibody and complement-mediated glial response and demyelination

Berg, C., Khorooshi, R., Asgari, N., Linington, C., Morgan, P. B. & Owens, T., 2015, In : Glia. 63, S1, p. E361-E362 T12-06B.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Aquaporin-4-autoimmunity and association to systemic lupus erythematosus: A predominantly population-based study

Asgari, N., Jarius, S., Laustrup, H., Lillevang, S. T. & Voss, A., 2015, In : Multiple Sclerosis Journal. 21, S1, p. 374 1 p., P752.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
183 Downloads (Pure)

Aquaporin-4-Immunoglobulin G-autoimmune syndrome in a Paraneoplastic Context

Soelberg, K., Grauslund, J., Lillevang, S. T. & Asgari, N., Mar 2015. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

File

CD11c(+) microglia are potent producers of IGF-1 during postnatal neurodevelopment

Wlodarczyk, A., Martin, N. & Owens, T., 2015, In : Glia. 63, S1, p. E253 1 p., T08-43B.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
95 Downloads (Pure)

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier

Asgari, N., Berg, C. T., Mørch, M. T., Khorooshi, R. & Owens, T., Aug 2015, In : Annals of Clinical and Translational Neurology. 2, 8, p. 857-63

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cerebrospinal Fluid
Neuromyelitis Optica
Horseradish Peroxidase

Demographic and clinical features of neuromyelitis optica: A review

Pandit, L., Asgari, N., Apiwattanakul, M., Palace, J., Paul, F., Leite, M. I., Kleiter, I. & Chitnis, T., 2015, In : Multiple Sclerosis Journal. 21, 7, p. 845-853

Research output: Contribution to journalReviewResearchpeer-review

Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia

Inacio, A. R., Liu, Y., Clausen, B. H., Svensson, M., Kucharz, K., Yang, Y., Stankovich, T., Khorooshi, R. M. H., Lambertsen, K. L., Issazadeh-Navikas, S. & Deierborg, T., 2015, In : Journal of Neuroinflammation. 12, 18 p., 211.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

EXPERT OPINIONS ON THE DIAGNOSIS AND TREATMENT OF PATIENTS WITH AQP4-NEGATIVE NMO/MS OVERLAPPING SYNDROMES

Juryńczyk, M., Weinshenker, B. G., Wingerchuk, D., Akman-Demir, G., Asgari, N., Barnes, D., Boggild, M., Chaudhuri, A. & Leite, M. I., 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 11, p. e4 1 p.

Research output: Contribution to journalConference abstract in journalResearch

86 Downloads (Pure)

Hypersensitivity Responses in the Central Nervous System

Khorooshi, R., Asgari, N., Mørch, M. T., Berg, C. T. & Owens, T., 2015, In : Frontiers in Immunology. 6, 13 p., 517.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neuromyelitis Optica
Hypersensitivity
Central Nervous System
Pathology
Macrophages
122 Downloads (Pure)

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

Khorooshi, R., Mørch, M. T., Holm, T., Berg, C. T., Dieu, R. T., Dræby, D., Issazadeh-Navikas, S., Weiss, S., Lienenklaus, S. & Owens, T., 14. Apr 2015, In : Acta Neuropathologica. 130, 1, p. 107-118

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Autoimmune Experimental Encephalomyelitis
Central Nervous System
Interferon-alpha
Interferon Inducers
Interferon Receptors

Interferon-beta induced within the CNS plays a protective role in EAE

Khorooshi, R. M. H., Mørch, M., Holm, T. H., Berg, C. T., Dieu, R., Dræby, D., Weiss, S., Lienenklaus, S. & Owens, T., 2015, In : Glia. 63, S1, p. E336 T12-37A .

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Microglia as regulators of T cell response in the CNS

Owens, T., 2015, In : Glia. 63, S1, p. E44-E45 S16-02.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Microglial regulation of CNS inflammation

Owens, T., Khorooshi, R. M. H., Mørch, M., Wlodarczyk, A., Hermansen, C. & Steckelings, U. M., 2015, In : Irish Journal of Medical Science. 184, S1, p. 5 1 p., S1.2.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access