Research Output

2011

Dose - and time dependent theraprutic and adverse effects of Mucuna pruriens extract in the 6-OHDA rat model of Parkinson's disease

Gramsbergen, J. B., 2011.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Effects on DHEA levels by estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism.

Fex Svenningsen, Å., Wicher, G., Lundqvist, J., Pettersson, H. & Norlin, M., 2011, In : Neurochemistry International. 58, p. 620-624 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Enhanced proliferation and dopaminergic differentiation of ventral mesencephalic precursor cells by synergistic effect of FGF2 and reduced oxygen tension

Jensen, P., Gramsbergen, J-B., Zimmer, J., Widmer, H. R. & Meyer, M., 2011, In : Experimental Cell Research. 317, 12, p. 1649-62 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of IL-1β and TNF-α in Alzheimer's pathology in mice

Finsen, B., 1. Jul 2011, In : Alzheimer's & Dementia. 7, 4, p. 685

Research output: Contribution to journalConference abstract in journalResearch

Feeder free differentiation of A9 and A10 type dopaminergic neurons from human pluripotent stem cells using small molecules

Cooper, O., Sundberg, M., Bogetofte, H., Seo, H., Deleidi, M., Osborn, T., Perez-Torres, E., Lawson, T. & Isacson, O., 2011.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Identification of Nitrotyrosine Containing Peptides using Combined Fractional Diagonal Chromatography (COFRADIC) and Off-Line Nano-LC-MALDI

Larsen, T. R., Bache, N., Gramsbergen, J. B. & Roepstorff, P., 1. Jun 2011, In : Journal of The American Society for Mass Spectrometry. 22, 6, p. 989-96 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

INCREASED DESENSITIZATION OF DOPAMINE D-2 RECEPTOR-MEDIATED RESPONSE IN THE VENTRAL TEGMENTAL AREA IN THE ABSENCE OF ADENOSINE A(2A) RECEPTORS

Al-Hasani, R., Foster, J. D., Metaxas, A., Ledent, C., Hourani, S. M. O., Kitchen, I. & Chen, Y., 2011, In : Neuroscience.

Research output: Contribution to journalJournal articleResearchpeer-review

Influence of lipid rafts on CD1d presentation by dendritic cells

Peng, W., Martaresche, C., Escande-Beillard, N., Cédile, O., Reynier-Vigouroux, A. & Boucraut, J., 2011, In : Molecular Membrane Biology. 24, 5-6, p. 475-84 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease

Toft-Hansen, H., Füchtbauer, L. & Owens, T., 1. Jan 2011, In : Glia. 59, 1, p. 166-76 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Innate immune responses in central nervous system inflammation

Finsen, B. & Owens, T., 2011, In : FEBS Letters. 585, 23, p. 3606-3612

Research output: Contribution to journalReviewResearchpeer-review

Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

Salem, M., Mony, J. T., Lobner, M., Khorooshi, R. & Owens, T., 2011, In : Journal of Neuroinflammation. 8, 1, p. 181

Research output: Contribution to journalJournal articleResearchpeer-review

In vivo uptake of beta-amyloid stimulates apoptosis but not proliferation of microglia and macrophages

Babcock, A., 2011.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Long-Term Propagation of Neural Stem Cells: Focus on Three-Dimensional Culture Systems and Mitogenic Factors

Andersen, R. K., Zimmer, J. & Meyer, M., 2011, Stem Cells & Regenerative Medicine: From Molecular Embryology to Tissue Engineering. Appasani, K. & Appasani, R. K. (eds.). Totowa, NJ: Humana Press, (Stem Cell Biology and Regenerative Medicine).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells

Zheng, L., Terman, A., Hallbeck, M., Dehvari, N., Cowburn, R. F., Benedikz, E., Kågedal, K., Cedazo-Minguez, A. & Marcusson, J., 2011, In : Autophagy. 7, 12, p. 1528-1545

Research output: Contribution to journalJournal articleResearchpeer-review

MALDI mass spectrometry based molecular phenotyping of CNS glial cells for prediction in mammalian brain tissue

Hanrieder, J., Wicher, G., Bergquist, J., Andersson, M. & Fex Svenningsen, Å., 7. May 2011, In : Analytical and Bioanalytical Chemistry. 401, 1, p. 135-147

Research output: Contribution to journalJournal articleResearchpeer-review

Measurement of ionised calcium is influenced by albumin concentration - an old but still relevant issue?

Larsen, T. R., Pennerup, L. & Antonsen, S., 15. May 2011.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearch

Microglia - insights into immune system structure, function, and reactivity in the central nervous system

Wirenfeldt, M., Babcock, A. A. & Vinters, H. V., 2011, In : Histology and Histopathology. 26, 4, p. 519-30 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Neuromyelitis optica (NMO): an autoimmune disease of the central nervous system (CNS)

Asgari, N., Owens, T., Frøkiaer, J., Stenager, E., Lillevang, S. T. & Kyvik, K. O., 2011, In : Acta Neurologica Scandinavica. 123, 6, p. 369-384

Research output: Contribution to journalJournal articleResearchpeer-review

RAE-1 is expressed in the adult subventricular zone and controls cell proliferation of neurospheres

Popa, N., Cédile, O., Pollet-Villard, X., Bagnis, C., Durbec, P. & Boucraut, J., 1. Jan 2011, In : Glia. 59, 1, p. 35-44 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Reparation med stamceller - realistisk, hvordan og hvornår?

Meyer, M., Zimmer, J. & Jensen, P., 2011, In : ParkinsonNyt. 1, p. 14-18

Research output: Contribution to journalJournal articleCommunication

Reversible neural stem cell niche dysfunction in a model of multiple sclerosis

Rasmussen, S., Imitola, J., Ayuso-Sacido, A., Wang, Y., Starossom, S. C., Kivisäkk, P., Zhu, B., Meyer, M., Bronson, R. T., Garcia-Verdugo, J. M. & Khoury, S. J., 2011, In : Annals of Neurology. 69, 5, p. 878-891

Research output: Contribution to journalJournal articleResearchpeer-review

Serotonin depleted APP/PS1 mice as a model to study neuropathology in Alzheimer's dementia

Severino, M., Kruse, C. R., Gramsbergen, J. B. & Finsen, B., 2011, In : Alzheimer's & Dementia. 7, 4, Suppl., p. S570 1 p., P3-167.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

SKA-31, an activator of KCa3.1/KCa2.3 channels, produces endothelial hyperpolarization and instantly lowers blood pressure in conscious dogs

Köhler, R., Damkjær, M., Nielsen, G., Stæhr, M., Jensen, B. L., Bie, P. & Gramsbergen, J. B., 2011, In : F A S E B Journal. 25, 808.7

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Stem cell therapy for neurological disorders

Meyer, M., Jensen, P. & Zimmer, J., 2011, In : Ugeskrift for Laeger. 38, p. 2604-2608 4 p.

Research output: Contribution to journalReviewResearchpeer-review

Stimulation of adult oligodendrogenesis by myelin-specific T cells

Hvilsted Nielsen, H., Toft-Hansen, H., Lambertsen, K. L., Owens, T. & Finsen, B., 2011, In : American Journal of Pathology. 179, 4, p. 2028-41 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

The Role of toll-like receptors in CNS glial responses

Holm, T., 2011, Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet.

Research output: Book/anthology/thesis/reportPh.D. thesisResearch

The transcriptional repressor Zbtb20 is essential for specification of hippocampal projection neurons and territory in mice

Rosenthal, E. H., 7. Oct 2011. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearch

Validity of a Danish translation of the Multiple Sclerosis Neuropsychological Questionaire (MSNQ)

Sejbæk, T., Blaabjerg, M., Sprogøe, P. & Ravnborg, M., 2011, In : Multiple sclerosis. 17, suppl, p. S402

Research output: Contribution to journalConference abstract in journalResearch

2010

Activation of the nuclear receptor PPARγ by metabolites isolated from sage (Salvia officinalis L.)

Christensen, K. B., Jørgensen, M., Kotowska, D. E., Petersen, R. K., Kristiansen, K. & Christensen, L. P., 2010, In : Journal of Ethnopharmacology. 132, 1, p. 127-133 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

A Low Ethanol Dose Affects all Types of Cells in Mixed Long-Term Embryonic Cultures of the Cerebellum

Pickering, C., Wicher, G., Rosendahl, S., Schiöth, H. B. & Fex Svenningsen, Å., 14. Jan 2010, In : Basic & Clinical Pharmacology & Toxicology. 106, 6, p. 472-478 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Axonal plasticity elicits long-term changes in oligodendroglia and myelinated fibers

Drøjdahl, N., Nielsen, H. H., Gardi, J. E., Wree, A., Peterson, A. C., Nyengaard, J. R., Eyer, J. & Finsen, B., 1. Jan 2010, In : Glia. 58, 1, p. 29-42 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

CSF transthyretin neuroprotection in a mouse model of brain ischemia

Santos, S. D., Lambertsen, K. L., Clausen, B. H., Akinc, A., Alvarez, R., Finsen, B. & Saraiva, M. J., 1. Dec 2010, In : Journal of Neurochemistry. 115, 6, p. 1434-44 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Differential region-specific regulation of alpha 4 beta 2*nAChRs by self-administered and non-contingent nicotine in C57BL/6J mice

Metaxas, A., Bailey, A., Flavia Barbano, M., Galeote, L., Maldonado, R. & Kitchen, I., 2010, In : Addiction Biology.

Research output: Contribution to journalJournal articleResearchpeer-review

Dyskinesia and plasma DOPA levels in hemi-Parkinsonian rats after chronic oral administration of Mucuna pruriens seed extract or L-DOPA methyl ester

Jørgensen, M., Gramsbergen, J. B. & Christensen, L. P., 1. Jun 2010, In : Basic & Clinical Pharmacology & Toxicology. 107, Supplement 1, p. 361–362 2 p., 2364.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Expression of Astrocytic Type 2 Angiotensin Receptor in Central Nervous System Inflammation Correlates With Blood-Brain Barrier Breakdown

Füchtbauer, L., Toft-Hansen, H., Khorooshi, R. & Owens, T., 23. Apr 2010, In : Journal of Molecular Neuroscience. 42, 1, p. 89-98

Research output: Contribution to journalJournal articleResearchpeer-review

GABA(A) Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels

Young, S. Z., Platel, J-C., Nielsen, J. V., Jensen, N. A. & Bordey, A., 1. Jan 2010, In : Frontiers in cellular neuroscience. 4, p. 8

Research output: Contribution to journalJournal articleResearchpeer-review

Inflammation in the CNS and Th17 Responses Are Inhibited by IFN-{gamma}-Induced IL-18 Binding Protein

Millward, J. M., Pedersen, M. L., Wheeler, R. D. & Owens, T., 19. Jul 2010, In : Journal of Immunology. 185, 4, p. 2458-2466

Research output: Contribution to journalJournal articleResearchpeer-review

Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

Khorooshi, R. & Owens, T., 18. Jun 2010, In : Journal of Immunology. 185, 2, p. 1258-1264

Research output: Contribution to journalJournal articleResearchpeer-review

In Vitro Neurotoxicity of PBDE-99: Immediate and Concentration-Dependent Effects on Protein Expression in Cerebral Cortex Cells

Alm, H., Scholz, B., Kultima, K., Nilsson, A., Andrén, P. E., Savitski, M. M., Bergman, A., Stigson, M., Svenningsen, Å. F. & Dencker, L., 2010, In : Journal of Proteome Research. 9, 3, p. 1226-1235

Research output: Contribution to journalJournal articleResearchpeer-review

MDMA (Ecstasy) Decreases the Number of Neurons and Stem Cells in Embryonic Cortical Cultures

Kindlundh-Högberg, A. M. S., Pickering, C., Wicher, G., Hobér, D., Schiöth, H. B. & Svenningsen, Å. F., 2010, In : Cellular & Molecular Neurobiology. 30, 1, p. 13-21

Research output: Contribution to journalJournal articleResearchpeer-review

MDMA-evoked changes in the binding of dopamine D(2) receptor ligands in striatum of rats with unilateral serotonin depletion

Ostergaard, S. D., Alstrup, A. K. O., Gramsbergen, J. B., Minuzzi, L., Pedersen, K., Jensen, S. B., Doudet, D. & Cumming, P., 1. Jan 2010, In : Synapse. 64, 1, p. 70-82 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Mouse strain differences in locomotor, sensitisation and rewarding effect of heroin; association with alterations in MOP-r activation and dopamine transporter binding

Bailey, A., Metaxas, A., Al-Hasani, R., Keyworth, H. L., Forster, D. M. & Kitchen, I., 2010, In : European Journal of Neuroscience.

Research output: Contribution to journalJournal articleResearchpeer-review

Optimization of chemically defined cell culture media - Replacing fetal bovine serum in mammalian in vitro methods

van der Valk, J., Brunner, D., De Smet, K., Fex Svenningsen, Å., Honegger, P., Knudsen, L. E., Lindl, T., Noraberg, J., Price, A., Scarino, M. L. & Gstraunthaler, G., 31. Mar 2010, In : Toxicology in Vitro. 24, 4, p. 1053-1063 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Spatiotemporal distribution and function of N-cadherin in postnatal Schwann cells: A matter of adhesion?

Corell, M., Wicher, G., Limbach, C., Kilimann, M. W., Colman, D. R. & Fex Svenningsen, Å., 2010, In : Journal of Neuroscience Research. 88, 11, p. 2338-49 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Stamceller i behandlingen af neurodegenerative lidelser

Meyer, M., Jensen, P. & Zimmer, J., 20. Sep 2010, In : Ugeskrift for Laeger. 172, 38, p. 2604-2607 4 p.

Research output: Contribution to journalReviewResearchpeer-review