Research Output

2014

Diagnostik og behandling af neuromyelitis optica

Nielsen, H. H., Ravnborg, M. & Illes, Z., 23. Jun 2014, In : Ugeskrift for Laeger. 176, 26, p. 1220-1224

Research output: Contribution to journalJournal articleResearchpeer-review

Effect of monomethyl-fumarate on experimental stroke

Illés, Z., Clausen, B. H., Finsen, B., Nielsen, H. H., Lundberg, L. & Lambertsen, K. L., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 221 1 p.

Research output: Contribution to journalConference abstract in journalResearch

IGF1 producing CD11c(+) microglia emerge during postnatal neurodevelopment

Wlodarczyk, A., Martin, N. & Owens, T., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 93-93

Research output: Contribution to journalJournal articleResearchpeer-review

Inflammatory responses and plaque deposition in early stage Alzheimer's pathology in mice

Ilkjaer, L., Babcock, A., Myhre, C. L. & Finsen, B., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 154-155 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin

Krabbe, C., Bak, S. T., Jensen, P., von Linstow, C. U., Martinez-Serrano, A., Hansen, C. & Meyer, M., 2014, In : P L o S One. 9, 5, e96465.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Interferons in the central nervous system: A few instruments play many tunes

Owens, T., Khorooshi, R. M. H., Wlodarczyk, A. & Asgari, N., 2014, In : Glia. 62, 3, p. 339–355 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Kvalitetsutvärdering av biomedicin och närliggande huvudområden

Leffler, H., Fex Svenningsen, Å., Emgård, M., Krengel, U., Lundgren, E., Rehn, M., Eriksson, M. & Halle, T., 6. May 2014, 151 p. Universitetskanslerämbetet, Stockholm, Sverige.

Research output: Other contributionCommissioned

Open Access
File
62 Downloads (Pure)

Mechanisms underlying induction of antibody-mediated demyelination in muliple sclerosis

Berg, C. T., Khorooshi, R. M. H., Asgari, N. & Owens, T., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 55-56

Research output: Contribution to journalJournal articleResearchpeer-review

MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE

Thyagabhavan Mony, J., Khorooshi, R. & Owens, T., 19. Feb 2014, In : Multiple sclerosis. 20, 10, p. 1312-1321

Research output: Contribution to journalJournal articleResearchpeer-review

Multicentre Comparison of European Diagnostic AQP4 Antibody Assays

Waters, P., Reindl, M., Schanda, K., Kral, V., Nytrova, P., Sobek, O., Nielsen, H. H., Illés, Z., Barington, T., Lillevang, S. T., Stöcker, W., Rentzsch, K., Probst, C. & Saschenbrecker, S., 9. Nov 2014.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Myelin specific T cells induce inflammasome activation in microglia in zones of axonal degeneration

Grebing, M. M., Nielsen, H. H., Fenger, C., Clausen, B. H., von Linstow, C. U., Jensen, K. T., Soderman, M., Lambertsen, K. L., Thomassen, M., Kruse, T. A. & Finsen, B., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 151-151

Research output: Contribution to journalJournal articleResearchpeer-review

Neurodevelopmental disorders associated with dosage imbalance of ZBTB20 correlate with the morbidity spectrum of ZBTB20 candidate target genes

Rasmussen, M. B., Nielsen, J. V., Lourenço, C. M., Melo, J. B., Halgren, C., Geraldi, C. V. L., Marques, W., Rodrigues, G. R., Thomassen, M., Bak, M., Hansen, C., Ferreira, S. I., Venâncio, M., Henriksen, K. F., Lind-Thomsen, A., Carreira, I. M., Jensen, N. A. & Tommerup, N., Sep 2014, In : Journal of Medical Genetics. 51, 9, p. 605-613 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

Lambertsen, K. L., Østergaard, K., Clausen, B. H., Hansen, S., Stenvang, J., Thorsen, S. B., Meldgaard, M., Kristensen, B. W., Hansen, P. B. L., Sørensen, G. L. & Finsen, B., Jul 2014, In : Journal of Neuroinflammation. 11, 13 p., 123.

Research output: Contribution to journalJournal articleResearchpeer-review

Oxaliplatin-induced neuropathy in colorectal cancer: Many questions with few answers

Zedan, A., Hansen, T. F., Fex Svenningsen, Å. & Vilholm, O. J., Jun 2014, In : Clinical Colorectal Cancer. 13, 2, p. 73-80 8 p.

Research output: Contribution to journalReviewResearchpeer-review

Pericardial resistance arteries show biaxial mechanics and pressure dependent microarchitecture of the extracellular matrix

Bloksgaard, M., Leurgans, T., Rosenstand, K., Jensen, P. S., Hansen, M. L., Brewer, J. R., Bagatolli, L., Marcussen, N., Irmukhamedov, A., Rasmussen, L. M. & De Mey, J., 7. Sep 2014.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands

Nabuurs, R. J. A., Kapoerchan, V. V., Metaxas, A., de Jongh, S., de Backer, M., Welling, M. M., Jiskoot, W., Windhorst, A. D., Overkleeft, H. S., van Buchem, M. A., Overhand, M. & van der Weerd, L., 2014, In : Bioorganic & Medicinal Chemistry.

Research output: Contribution to journalJournal articleResearchpeer-review

Pregnancy outcomes in a woman with neuromyelitis optica

Asgari, N., Henriksen, T. B., Petersen, T., Lillevang, S. T. & Weinshenker, B. G., 21. Oct 2014, In : Neurology. 83, 17, p. 1576-1577

Research output: Contribution to journalComment/debateResearchpeer-review

Spontaneous temporal changes and variability of peripheral nerve conduction analyzed using a random effects model

Krøigård, T., Gaist, D., Otto, M., Højlund, D., Selmar, P. E. & Sindrup, S. H., Aug 2014, In : Journal of Clinical Neurophysiology. 31, 4, p. 387-91

Research output: Contribution to journalJournal articleResearchpeer-review

Structure-activity relationships of N-substituted 4-(trifluoromethoxy) benzamidines with affinity for GluN2B-containing NMDA receptors

Beinat, C., Banister, S. D., Hoban, J., Tsanaktsidis, J., Metaxas, A., Windhorst, A. D. & Kassiou, M., 2014, In : Bioorganic & Medicinal Chemistry Letters.

Research output: Contribution to journalJournal articleResearchpeer-review

Subchronic Treatment With Phencyclidine in Adolescence Leads to Impaired Exploratory Behavior in Adult Rats Without Altering Social Interaction or N-Methyl-D-Aspartate Receptor Binding Levels

Metaxas, A., Willems, R., Kooijman, E. J. M., Renjaan, V. A., Klein, P. J., Windhorst, A. D., Donck, L. V., Leysen, J. E. & van Berckel, B. N. M., 2014, In : Journal of Neuroscience Research.

Research output: Contribution to journalJournal articleResearchpeer-review

Suppressors of cytokine signaling 1 and 3 are up-regulated in brain resident cells in response to virus induced inflammation of the CNS via at least two distinctive pathways

Steffensen, M. A., Fenger, C., Christensen, J. E., Jørgensen, C. K., Bassi, M. R., Christensen, J. P., Finsen, B. & Thomsen, A. R., 24. Sep 2014, In : Journal of Virology. 88, 24, p. 14090-14104

Research output: Contribution to journalJournal articleResearchpeer-review

Synthesis and preclinical evaluation of carbon-11 labelled N-((5-(4-fluoro-2-[C-11]methoxyphenyl) pyridin-3-yl) methyl) cyclopentanamine as a PET tracer for NR2B subunit-containing NMDA receptors

Christiaans, J. A. M., Klein, P. J., Metaxas, A., Kooijman, E. J. M., Schuit, R. C., Leysen, J. E., Lammertsma, A. A., van Berckel, B. N. M. & Windhorst, A. D., 2014, In : Nuclear Medicine and Biology.

Research output: Contribution to journalJournal articleResearchpeer-review

Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

Clausen, B. H., Degn, M., Martin, N. A., Couch, Y., Karimi, L., Ormhøj, M., Mortensen, M-L. B., Gredal, H., Gardiner, C., Sargent, I. I. L., Szymkowski, D. E., Petit, G., Deierborg, T., Finsen, B., Anthony, D. & Lambertsen, K. L., 12. Dec 2014, In : Journal of Neuroinflammation. 11, 1, p. 203

Research output: Contribution to journalJournal articleResearchpeer-review

The complex immunology of multiple sclerosis

Owens, T., 16. Jun 2014, In : Multiple sclerosis. 20, 8, p. 1023-1024 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses

Marczynska, J., Ozga, A., Wlodarczyk, A., Majchrzak-Gorecka, M., Kulig, P., Banas, M., Michalczyk-Wetula, D., Majewski, P., Hutloff, A., Schwarz, J., Chalaris, A., Scheller, J., Rose-John, S. & Cichy, J., 15. Sep 2014, In : Journal of Immunology. 193, 6, p. 2753-63

Research output: Contribution to journalJournal articleResearchpeer-review

The water channel aquaporin-1 contributes to renin cell recruitment during chronic stimulation of renin production

Tinning, A. R., Jensen, B. L., Schweda, F., Machura, K., Hansen, P. B. L., Stubbe, J., Gramsbergen, J. B. & Madsen, K., 2014, In : American Journal of Physiology: Renal Physiology. 307, 11, p. F1215-F1226

Research output: Contribution to journalJournal articleResearchpeer-review

Thymic CCL2 influences induction of T-cell tolerance

Cédile, O., Løbner, M., Toft-Hansen, H., Frank, I., Wlodarczyk, A., Irla, M. & Owens, T., 13. Aug 2014, In : Journal of Autoimmunity. 55, p. 73-85

Research output: Contribution to journalJournal articleResearchpeer-review

What is microglia neurotoxicity (Not)?

Biber, K., Owens, T. & Boddeke, E., Jun 2014, In : Glia. 62, 6, p. 841-854

Research output: Contribution to journalReviewResearchpeer-review

2013

Alternative polyadenylation and miR-34 family members regulate tau expression

Dickson, J. R., Kruse, C., Montagna, D. R., Finsen, B. & Wolfe, M. S., Dec 2013, In : Journal of Neurochemistry. 127, 6, p. 739-49

Research output: Contribution to journalJournal articleResearchpeer-review

A wonderful week of immunology in Copenhagen

Owens, T., 2013, In : Scandinavian Journal of Immunology. Supplement. 77, 4, p. 223

Research output: Contribution to journalJournal articleResearchpeer-review

Beta-amyloid induces apoptosis of phagocytotic microglia and macrophages. Glia, Volume 61, Issue Suppl 1, S63.

Babcock, A., Ilkjær, L., Nielsen, M. W., Myhre, C. L., Toft-Hansen, H., Olesen, L. D. & Finsen, B., 2013.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid

Asgari, N., Khorooshi, R., Lillevang, S. T. & Owens, T., 15. Jan 2013, In : Journal of Neuroimmunology. 254, 1-2, p. 76-82

Research output: Contribution to journalJournal articleResearchpeer-review

Detection and Cellular Localization of Phospho-STAT2 in the Central Nervous System by Immunohistochemical Staining

Khorooshi, R. & Owens, T., 2013, JAK-STAT Signalling : Methods and Protocols. Nicholson, S. E. & Nicola, N. A. (eds.). Springer, p. 179-88 10 p. (Methods in Molecular Biology, Vol. 967).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Distinct subsets of interleukin-1 receptor antagonist producing cells are neuroprotective after focal cerebral ischemia in mice

Clausen, B. H., 2013.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Distinct subsets of interleukin-1 receptor antagonist producing cells are neuroprotective after focal cerebral ischemia in mice. Glia, Volume 61, Issue Suppl 1, S130

Clausen, B. H., Lambertsen, K. L., Babcock, A., von Linstow, C. U. & Finsen, B., 2013.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

DNA structures decorated with cathepsin G/secretory leukocyte proteinase inhibitor stimulate IFNI production by plasmacytoid dendritic cells

Skrzeczynska-Moncznik, J., Wlodarczyk, A., Banas, M., Kwitniewski, M., Zabieglo, K., Kapinska-Mrowiecka, M., Dubin, A. & Cichy, J., 2013, In : American journal of clinical and experimental immunology. 2, 2, p. 186-94

Research output: Contribution to journalJournal articleResearchpeer-review

Epidemiological, clinical and immunological aspects of neuromyelitis optica (NMO)

Asgari, N., 2013, In : Danish Medical Journal. 60, 10, B4730.

Research output: Contribution to journalJournal articleResearchpeer-review

Evolution of longitudinally extensive transverse myelitis in an aquaporin-4 IgG-positive patient

Asgari, N., Skejoe, H. P. B. & Lennon, V. A., 2013, In : Neurology. 81, 1, p. 95-96 2 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Expression of Trefoil factor 1 in the developing and adult rat ventral mesencephalon

Jensen, P., Heimberg, M., Ducray, A. D., Widmer, H. R. & Meyer, M., 7. Oct 2013, In : P L o S One. 8, 10, 12 p., e76592.

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of Zinc Finger Protein 804A (ZNF804A) in the brain

Benedikz, E., 2013.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Function of the Nkx2.2 transcription factor in oligodendrocytes and their progenitor cells. Glia, Volume 61, Issue Suppl 1, S49.

Finsen, B. & Fenger, C., 2013.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Genetic deletion of the adenosine A(2A) receptor prevents nicotine-induced upregulation of alpha 7, but not alpha 4 beta 2*nicotinic acetylcholine receptor binding in the brain

Metaxas, A., Al-Hasani, R., Farshim, P., Tubby, K., Berwick, A., Ledent, C., Hourani, S., Kitchen, I. & Bailey, A., 2013, In : Neuropharmacology.

Research output: Contribution to journalJournal articleResearchpeer-review

Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons

Sundberg, M., Bogetofte, H., Lawson, T., Jansson, J., Smith, G., Astradsson, A., Moore, M., Osborn, T., Cooper, O., Spealman, R., Hallett, P., Isacson, O. & Bogetofte Thomasen, H., Aug 2013, In : Stem Cells. 31, 8, p. 1548-62 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Inhibition of Astroglial NFkappaB enhances oligodendrogenesis following spinal cord injury

Bracchi-Ricard, V., Lambertsen, K. L., Ricard, J., Nathanson, L., Karmally, S., Johnstone, J., Ellman, D. G., Frydel, B., McTigue, D. M. & Bethea, J. R., 2013, In : Journal of Neuroinflammation. 10, 1, p. 92

Research output: Contribution to journalJournal articleResearchpeer-review

In situ hybridization of cytokine mRNA using alkaline phosphatase-labelled oligodeoxynucleotide probes

Clausen, B. H., Fenger, C. & Finsen, B., 2013, In : Methods in Molecular Biology. 1041, p. 83-91

Research output: Contribution to journalJournal articleResearchpeer-review

Interferon alpha association with neuromyelitis optica

Asgari, N., Voss, A., Steenstrup, T., Kyvik, K. O., Stenager, E. & Lillevang, S. T., 2013.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearch

Interferon alpha association with neuromyelitis optica

Asgari, N., Voss, A., Steenstrup, T., Kyvik, K. O., Stenager, E. & Lillevang, S. T., 2013, In : Clinical & Developmental Immunology. 2013, 713519.

Research output: Contribution to journalJournal articleResearchpeer-review

Islet-1 is a dual regulator of fibrogenic epithelial-to-mesenchymal transition in epicardial mesothelial cells

Brønnum, H., Andersen, D. C., Schneider, M., Yaël Nossent, A., Nielsen, S. B. & Sheikh, S. P., 15. Feb 2013, In : Experimental Cell Research. 319, 4, p. 424-435

Research output: Contribution to journalJournal articleResearchpeer-review

Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia

Maiorino, C., Khorooshi, R., Ruffini, F., Løbner, M., Bergami, A., Garzetti, L., Martino, G., Owens, T. & Furlan, R., May 2013, In : Gene Therapy Weekly. 20, 5, p. 487-96 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Microdialysis and microfiltration: Technology and cerebral applications for energy substrates.

Gramsbergen, J. B., 2013, Neural Metabolism In Vivo, Advances in Neurobiology 4. Choi, I-Y. & Gruetter, R. (eds.). Springer Science+Business Media, (Advances in Neurobiology, Vol. 4).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review