Research Output

2015

GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination

Corell, M., Wicher, G., Radomska, K. J., Daglikoca, E. D., Godskesen, R. E., Fredriksson, R., Benedikz, E., Magnaghi, V. & Fex Svenningsen, Å., 1. Feb 2015, In : Journal of Neuroscience Research. 3, 93, p. 285-295 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Group I Metabotropic Glutamate Receptors: A Potential Target for Regulation of Proliferation and Differentiation of an Immortalized Human Neural Stem Cell Line

Erichsen, J. L., Blaabjerg, M., Bogetofte Thomasen, H., Serrano, A. M. & Meyer, M., 2015, In : Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 329-336

Research output: Contribution to journalJournal articleResearchpeer-review

Histologi: Tekst & Atlas

Gude, M. F., Dall, A. M., Veedfald, S. & Brügmann, A. H., 2015, 1. ed. FADL's Forlag. 434 p.

Research output: Book/anthology/thesis/reportBookEducationpeer-review

Hypersensitivity Responses in the Central Nervous System

Khorooshi, R., Asgari, N., Mørch, M. T., Berg, C. T. & Owens, T., 2015, In : Frontiers in Immunology. 6, 13 p., 517.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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150 Downloads (Pure)

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis

Khorooshi, R., Mørch, M. T., Holm, T., Berg, C. T., Dieu, R. T., Dræby, D., Issazadeh-Navikas, S., Weiss, S., Lienenklaus, S. & Owens, T., 14. Apr 2015, In : Acta Neuropathologica. 130, 1, p. 107-118

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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175 Downloads (Pure)

Interferon-beta induced within the CNS plays a protective role in EAE

Khorooshi, R. M. H., Mørch, M., Holm, T. H., Berg, C. T., Dieu, R., Dræby, D., Weiss, S., Lienenklaus, S. & Owens, T., 2015, In : Glia. 63, S1, p. E336 T12-37A .

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Microglia as regulators of T cell response in the CNS

Owens, T., 2015, In : Glia. 63, S1, p. E44-E45 S16-02.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Microglial regulation of CNS inflammation

Owens, T., Khorooshi, R. M. H., Mørch, M., Wlodarczyk, A., Hermansen, C. & Steckelings, U. M., 2015, In : Irish Journal of Medical Science. 184, S1, p. 5 1 p., S1.2.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Microglial TNF and IL-1 as early disease-modifiers in Alzheimer's-like disease in mice

Ilkjær, L., Babcock, A. & Finsen, B., 2015, In : Glia. 63, S1, p. E52-E53 S20-02 .

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

MRI characteristics of neuromyelitis optica spectrum disorder An international update

Kim, H. J., Paul, F., Lana-Peixoto, M. A., Tenembaum, S., Asgari, N., Palace, J., Klawiter, E. C., Sato, D. K., de Seze, J., Wuerfel, J., Banwell, B. L., Villoslada, P., Saiz, A., Fujihara, K. & Kim, S. H., 2015, In : Neurology. 84, 11, p. 1165-1173

Research output: Contribution to journalJournal articleResearchpeer-review

Neuroinflammation in Alzheimer's disease

Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., Herrup, K., Frautschy, S. A., Finsen, B., Brown, G. C., Verkhratsky, A., Yamanaka, K., Koistinaho, J., Latz, E., Halle, A., Petzold, G. C. & 17 others, Town, T., Morgan, D., Shinohara, M. L., Perry, V. H., Holmes, C., Bazan, N. G., Brooks, D. J., Hunot, S., Joseph, B., Deigendesch, N., Garaschuk, O., Boddeke, E., Dinarello, C. A., Breitner, J. C., Cole, G. M., Golenbock, D. T. & Kummer, M. P., Apr 2015, In : Lancet Neurology. 14, 4, p. 388-405 18 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

Bennett, J. L., de Seze, J., Lana-Peixoto, M., Palace, J., Waldman, A., Schippling, S., Tenembaum, S., Banwell, B., Greenberg, B., Levy, M., Fujihara, K., Chan, K. H., Kim, H. J., Asgari, N., Sato, D. K., Saiz, A., Wuerfel, J., Zimmermann, H., Green, A., Villoslada, P. & 1 others, Paul, F., 2015, In : Multiple Sclerosis Journal. 21, 6, p. 678-688

Research output: Contribution to journalReviewResearchpeer-review

Neuromyelitis optica IgG in the cerebrospinal fluid induces astrocytopathy in optic nerve

Soelberg, K., Lillevang, S. T., Mørch, M., Khorooshi, R. M. H., Berg, C. T., Morgan, P., Asgari, N. & Owens, T., Oct 2015. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Non-traditional Models: The Giraffe Kidney from a Comparative and Evolutionary Biology Perspective

Damkjær, M., Wang, T., Østergaard, K. H., Brøndum, E. T., Baandrup, U., Hørlyck, A., Hasenkam, J. M., Marcussen, N., Danielsen, C. C., Bertelsen, M. F., Grøndahl, C., Pedersen, M., Agger, P., Candy, G., Chemnitz, J., Aalkjær, C. & Bie, P., 2015, Sodium and Water Homeostasis: Comparative, Evolutionary and Genetic Models. Hyndman, K. A. & Pannabecker, T. L. (eds.). Springer, p. 233-253 (Physiology in Health and Disease).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation

Wlodarczyk, A., Cédile, O., Jensen, K. N., Jasson, A., Mony, J. T., Khorooshi, R. & Owens, T., 2015, In : Frontiers in Immunology. 6, 11 p., 463.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
156 Downloads (Pure)

Patient reported outcome in posttraumatic pituitary deficiency: results from The Danish National Study on posttraumatic hypopituitarism

Klose, M., Stochholm, K., Janukonyté, J., Christensen, L. L., Cohen, A. S., Wagner, A., Laurberg, P., Christiansen, J. S., Andersen, M. & Feldt-Rasmussen, U., 2015, In : European Journal of Endocrinology. 172, 6, p. 753-762

Research output: Contribution to journalJournal articleResearchpeer-review

Phosphodiesterase4D (PDE4D)--A risk factor for atrial fibrillation and stroke?

Jørgensen, C., Yasmeen, S., Iversen, H. K. & Kruuse, C., 15. Dec 2015, In : Journal of the Neurological Sciences. 359, 1-2, p. 266-74 9 p.

Research output: Contribution to journalReviewResearchpeer-review

Preclinical evaluation of [F-18]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors

Golla, S. S. V., Klein, P. J., Bakker, J., Schuit, R. C., Christiaans, J. A. M., van Geest, L., Kooijman, E. J. M., Oropeza-Seguias, G. M., Langermans, J. A. M., Leysen, J. E., Boellaard, R., Windhorst, A. D., van Berckel, B. N. M. & Metaxas, A., 2015, In : Nuclear Medicine and Biology.

Research output: Contribution to journalJournal articleResearchpeer-review

Preserved Cerebral Microcirculation After Cardiac Arrest in a Rat Model

Secher, N., Østergaard, L., Iversen, N. K., Lambertsen, K. L., Clausen, B. H., Tønnesen, E. & Granfeldt, A., 2015, In : Microcirculation. 22, 6, p. 464-474

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Protective Effects of Surfactant Protein D (SP-D) Treatment in 1,3-β-glucan-modulated Allergic Inflammation

Fakih, D., Pilecki, B., Schlosser, A., Jepsen, C. E. S., Thomsen, L. K., Ormhøj, M., Watson, A., Madsen, J., Clark, H. W., Barfod, K. K., Hansen, S. W. K., Marcussen, N., Jounblat, R., Chamat, S., Holmskov, U. & Sorensen, G. L., 2. Oct 2015, In : American Journal of Physiology: Lung Cellular and Molecular Physiology. 309, 11, p. L1333-L1343

Research output: Contribution to journalJournal articleResearchpeer-review

Quantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes and Lower Levels among Metformin Users

Rørdam Preil, S., Kristensen, L. P., Beck, H. C., Jensen, P. S., Nielsen, P. S., Steiniche, T., Bjørling-Poulsen, M., Larsen, M. R., Hansen, M. L. & Rasmussen, L. M., 14. Sep 2015, In : Circulation: Cardiovascular Genetics. 8, p. 727-35

Research output: Contribution to journalJournal articleResearchpeer-review

Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration

Zanos, P., Georgiou, P., Metaxas, A., Kitchen, I., Winsky-Sommerer, R. & Bailey, A., 2015, In : Neuroscience Letters.

Research output: Contribution to journalJournal articleResearchpeer-review

Role of neuroinflammation in progression of Alzheimer's disease

Ilkjær, L., 2015, Odense: Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet. 147 p.

Research output: Book/anthology/thesis/reportPh.D. thesisResearch

Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development

Venø, M. T., Hansen, T. B., Venø, S. T., Clausen, B. H., Grebing, M., Finsen, B., Holm, I. E. & Kjems, J., 2015, In : Genome Biology (Online Edition). 16, November , 17 p., 245.

Research output: Contribution to journalJournal articleResearchpeer-review

Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-D-aspartate receptor as potential imaging probes for positron emission tomography

Klein, P. J., Christiaans, J. A. M., Metaxas, A., Schuit, R. C., Lammertsma, A. A., van Berckel, B. N. M. & Windhorst, A. D., 2015, In : Bioorganic & Medicinal Chemistry.

Research output: Contribution to journalJournal articleResearchpeer-review

Telomere dysfunction reduces microglial numbers without fully inducing an aging phenotype.

Khan, A. M., Babcock, A., Saeed, H., Myhre, C. L., Kassem, M. & Finsen, B., 2015, In : Neurobiology of Aging. 36, 6, p. 2164-75 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

The impact of TNFalpha on the developing brain

Breton, A., Stolp, H., Ferrara, L., Lundberg, L., Sa-Pereira, I., Finsen, B., Clausen, B. H., Lambertsen, K. L. & Anthony, D., 2015, In : Glia. 63, S1, p. E305-E306 T11-02B.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

The Rat Homolog of the Schizophrenia Susceptibility Gene ZNF804A Is Highly Expressed during Brain Development, Particularly in Growth Cones

Hinna, K. H., Rich, K., Fex Svenningsen, Å. & Benedikz, E., 2015, In : P L o S One. 10, 7, 13 p., e0132456.

Research output: Contribution to journalJournal articleResearchpeer-review

The Urine Proteome Profile Is Different in Neuromyelitis Optica Compared to Multiple Sclerosis: A Clinical Proteome Study

Nielsen, H. H., Beck, H. C., Kristensen, L. P., Burton, M., Csepany, T., Simo, M., Dioszeghy, P., Sejbaek, T., Grebing, M., Heegaard, N. H. H. & Illes, Z., 2015, In : PLOS ONE. 10, 10, p. e0139659

Research output: Contribution to journalJournal articleResearchpeer-review

The Urine Proteome Profile Is Different in Neuromyelitis Optica Compared to Multiple Sclerosis: A Clinical Proteome Study

Nielsen, H. H., Beck, H. C., Kristensen, L. P., Burton, M., Csepany, T., Simo, M., Dioszeghy, P., Mathiesen, T. S., Grebing, M., Heegaard, N. & Illés, Z., 8. Oct 2015.

Research output: Contribution to conference without publisher/journalPosterResearch

Udredning og behandling af autoimmun encefalitis Workup and treatment of autoimmune encephalitis

Blaabjerg, M., Mærsk-Møller, C. C., Kondziella, D., Somnier, F., Celicanin, M., Andersen, H., Bach, F. W. & Pinborg, L. H., 2. Nov 2015, In : Ugeskrift for Laeger. 177, 45, p. 2-7 V05150448.

Research output: Contribution to journalJournal articleResearchpeer-review

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder

Kremer, S., Renard, F., Achard, S., Lana-Peixoto, M. A., Palace, J., Asgari, N., Klawiter, E. C., Tenembaum, S. N., Banwell, B., Greenberg, B. M., Bennett, J. L., Levy, M., Villoslada, P., Saiz, A., Fujihara, K., Chan, K. H., Schippling, S., Paul, F., Kim, H. J., de Seze, J. & 1 others, Wuerfel, J. T., 2015, In : J A M A Neurology. 72, 7, p. 815-822

Research output: Contribution to journalReviewResearchpeer-review

2014

Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

Baron, R., Babcock, A. A., Nemirovsky, A., Finsen, B. & Monsonego, A., 2014, In : Aging Cell. 13, 4, p. 584-595

Research output: Contribution to journalJournal articleResearchpeer-review

Antibodies against interferon-beta in neuromyelitis optica patients

Asgari, N., Kyvik, K. O., Steenstrup, T., Stenager, E. & Lillevang, S. T., 15. Apr 2014, In : Journal of the Neurological Sciences. 339, 1-2, p. 52-56

Research output: Contribution to journalJournal articleResearchpeer-review

Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

Brambilla, R., Morton, P. D., Ashbaugh, J. J., Karmally, S., Lambertsen, K. L. & Bethea, J. R., Mar 2014, In : Glia. 62, 3, p. 452-467

Research output: Contribution to journalJournal articleResearchpeer-review

Brain-derived microvesicles confer sickness behaviours by switching on the acute phase response in the liver

Couch, Y., Evans, M. C., Gardiner, C., Sargent, I., Losey, P., Lambertsen, K. L. & Anthony, D. C., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 57

Research output: Contribution to journalJournal articleResearchpeer-review

CCL2 Chemokine in Central Tolerance

Cedile, O., Lobner, M., Toft-Hansen, H., Frank, I., Wlodarczyk, A., Irla, M. & Owens, T., 2014, In : Scandinavian Journal of Immunology. 79, 6, p. 452-453

Research output: Contribution to journalConference abstract in journalResearchpeer-review

CCL2 chemokine in T cell tolerance and protection against experimental autoimmune encephalomyelitis

Cedile, O., Lobner, M., Toft-Hansen, H., Frank, I., Wlodarczyk, A., Irla, M. & Owens, T., 2014, In : Journal of Neuroimmunology. 275, 1-2 (Special issue), p. 197-197

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Cell therapy for Parkinson's disease - status and perspectives

Meyer, M. & Jensen, P., 2014, In : BestPractice. 25, p. 42-45 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

Novrup, H. G., Bracchi-Ricard, V., Ellman, D. G., Ricard, J., Jain, A., Runko, E., Lyck, L., Yli-Karjanmaa, M., Szymkowski, D. E., Lambertsen, K. L. & Bethea, J. R., 10. Sep 2014, In : Journal of Neuroinflammation. 11, 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cerebral Level of vGlut1 is Increased and Level of Glycine is Decreased in TgSwDI Mice

Timmer, N. M., Metaxas, A., van der Stelt, I., Kluijtmans, L. A. J., van Berckel, B. N. & Verbeek, M. M., 2014, In : Journal of Alzheimers Disease.

Research output: Contribution to journalJournal articleResearchpeer-review

Chemokine receptor expression by inflammatory T cells in EAE

Mony, J. T., Khorooshi, R. & Owens, T., 2014, In : Frontiers in cellular neuroscience. 8, 9 p., 187.

Research output: Contribution to journalJournal articleResearchpeer-review

CLIPPERS among patients diagnosed with non-specific CNS neuroinflammatory diseases

Kerrn-Jespersen, B. M., Lindelof, M., Illes, Z., Blaabjerg, M., Lund, E. L., Klausen, C., Christiansen, I., Sellebjerg, F. & Kondziella, D., 15. Aug 2014, In : Journal of the Neurological Sciences. 343, 1-2, p. 224-7

Research output: Contribution to journalJournal articleResearchpeer-review

Comparison of microglia and infiltrating CD11c+ cells as antigen presenting cells for T cell proliferation and cytokine response

Wlodarczyk, A., Løbner, M., Cédile, O. & Owens, T., 25. Mar 2014, In : Journal of Neuroinflammation. 11, 1, 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Diagnostik og behandling af neuromyelitis optica

Nielsen, H. H., Ravnborg, M. & Illes, Z., 23. Jun 2014, In : Ugeskrift for Laeger. 176, 26, p. 1220-1224

Research output: Contribution to journalJournal articleResearchpeer-review

Effect of monomethyl-fumarate on experimental stroke

Illés, Z., Clausen, B. H., Finsen, B., Nielsen, H. H., Lundberg, L. & Lambertsen, K. L., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 221 1 p.

Research output: Contribution to journalConference abstract in journalResearch

IGF1 producing CD11c(+) microglia emerge during postnatal neurodevelopment

Wlodarczyk, A., Martin, N. & Owens, T., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 93-93

Research output: Contribution to journalJournal articleResearchpeer-review

Inflammatory responses and plaque deposition in early stage Alzheimer's pathology in mice

Ilkjaer, L., Babcock, A., Myhre, C. L. & Finsen, B., 2014, In : Journal of Neuroimmunology. 275, 1-2, p. 154-155 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin

Krabbe, C., Bak, S. T., Jensen, P., von Linstow, C. U., Martinez-Serrano, A., Hansen, C. & Meyer, M., 2014, In : P L o S One. 9, 5, e96465.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access