Research Output

Expansion and characterization of ventral mesencephalic precursor cells: effect of mitogens and investigation of FA1 as a potential dopaminergic marker.

Jensen, P., Bauer, M., Jensen, C. H., Widmer, H. R., Gramsbergen, J. B., Blaabjerg, M., Zimmer, J. & Meyer, M., 1. Jul 2007, In : Journal of Neuroscience Research. 85, 9, p. 1884-93 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice

Martin, N. A., Molnar, V., Szilagyi, G. T., Elkjaer, M. L., Nawrocki, A., Okarmus, J., Wlodarczyk, A., Thygesen, E. K., Palkovits, M., Gallyas, F., Larsen, M. R., Lassmann, H., Benedikz, E., Owens, T., Svenningsen, A. F. & Illes, Z., 2018, In : Frontiers in Immunology. 9, 14 p., 490.

Research output: Contribution to journalJournal articleResearchpeer-review

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EXPERT OPINIONS ON THE DIAGNOSIS AND TREATMENT OF PATIENTS WITH AQP4-NEGATIVE NMO/MS OVERLAPPING SYNDROMES

Juryńczyk, M., Weinshenker, B. G., Wingerchuk, D., Akman-Demir, G., Asgari, N., Barnes, D., Boggild, M., Chaudhuri, A. & Leite, M. I., 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 11, p. e4 1 p.

Research output: Contribution to journalConference abstract in journalResearch

Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex

Alm, H., Kultima, K., Scholz, B., Nilsson, A., Andrén, P. E., Svenningsen, Å. F., Dencker, L. & Stigson, M., 2008, In : NeuroToxicology. 29, 4, p. 628-37 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: Potential effects of vitamin D on brain steroidogenesis.

Emanuelsson, I., Almokhtar, M., Wikvall, K., Grönbladh, A., Nylander, E., Svensson, AL., Fex Svenningsen, Å. & Norlin, M., 2018, In : Neurochemistry International. 113, p. 46-55

Research output: Contribution to journalJournal articleResearchpeer-review

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Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis

Amin, D. N., Rottenberg, M. E., Thomsen, A. R., Mumba, D., Fenger, C., Kristensson, K., Büscher, P., Finsen, B. & Masocha, W., 15. Nov 2009, In : Journal of Infectious Diseases. 200, 10, p. 1556-65 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of Astrocytic Type 2 Angiotensin Receptor in Central Nervous System Inflammation Correlates With Blood-Brain Barrier Breakdown

Füchtbauer, L., Toft-Hansen, H., Khorooshi, R. & Owens, T., 23. Apr 2010, In : Journal of Molecular Neuroscience. 42, 1, p. 89-98

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of IL-1β and TNF-α in Alzheimer's pathology in mice

Finsen, B., 1. Jul 2011, In : Alzheimer's & Dementia. 7, 4, p. 685

Research output: Contribution to journalConference abstract in journalResearch

Expression of major histocompatibility complex antigens and induction of human T-lymphocyte proliferation by astrocytes and macrophages from porcine fetal brain

Brevig, T., Kristensen, T. & Rasmussen, J. Z., 1999, In : Experimental Neurology. 159, p. 474-483

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of Pluripotency Markers in Nonpluripotent Human Neural Stem and Progenitor Cells

Vincent, P., Benedikz, E., Uhlén, P., Hovatta, O. & Sundström, E., 2017, In : Stem Cells and Development. 26, 12, p. 876-887

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of Trefoil factor 1 in the developing and adult rat ventral mesencephalon

Jensen, P., Heimberg, M., Ducray, A. D., Widmer, H. R. & Meyer, M., 7. Oct 2013, In : P L o S One. 8, 10, 12 p., e76592.

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of Zinc Finger Protein 804A (ZNF804A) in the brain

Benedikz, E., 2013.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Extracellular clusterin promotes neuronal network complexity in vitro

Wicher, G., Velsecchi, I., Charnay, Y., Aldskogius, H. & Svenningsen, Å. F., 2008, In : NeuroReport. 19, 15, p. 1487-91 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Feeder free differentiation of A9 and A10 type dopaminergic neurons from human pluripotent stem cells using small molecules

Cooper, O., Sundberg, M., Bogetofte, H., Seo, H., Deleidi, M., Osborn, T., Perez-Torres, E., Lawson, T. & Isacson, O., 2011.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Fluidic system for long-term in vitro culturing and monitoring of organotypic brain slices

Bakmand, T., Troels-Smith, A. R., Dimaki, M., Nissen, J. D., Andersen, K. B., Sasso, L., Waagepetersen, H. S., Gramsbergen, J. B. & Svendsen, W. E., Aug 2015, In : Biomedical Microdevices. 17, 4, p. 71

Research output: Contribution to journalJournal articleResearchpeer-review

Focal cerebral ischemia induces increased myelin basic protein and growth-associated protein-43 gene transcription in peri-infarct areas in the rat brain

Gregersen, R., Christensen, T., Lehrmann, E., Diemer, N. H. & Finsen, B., 2001, In : Experimental Brain Research. 138, p. 384-392

Research output: Contribution to journalJournal articleResearch

Four cases of gabab receptor encephalitis

Szots, M., Blaabjerg, M., Kondziella, D., Herceg, M., Dioszeghy, P., Bajzik, G., Berki, T., Kalman, E., Nagy, F. & Illes, Z., 2016, In : Ideggyogyaszati Szemle. 69, 7-8, p. 281-287

Research output: Contribution to journalJournal articleResearchpeer-review

Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade

Christensen, J. E., Simonsen, S., Fenger, C., Sørensen, M. R., Moos, T., Christensen, J. P., Finsen, B. & Thomsen, A. R., 15. Jan 2009, In : Journal of Immunology. 182, 2, p. 1079-87 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fumarate decreases edema volume and improves functional outcome after experimental stroke

Clausen, B. H., Lundberg, L., Yli-Karjanmaa, M. L. K., Martin, N. A., Svensson, M., Zeiler Alfsen, M., Flæng, S. B., Lyngsø, K. S., Boza-Serrano, A., Nielsen, H. H., Hansen, P. B. L., Finsen, B., Deierborg, T., Illés, Z. & Lambertsen, K. L., Sep 2017, In : Experimental Neurology. 295, p. 144–154

Research output: Contribution to journalJournal articleResearchpeer-review

Fumarate improves functional outcome of experimental ischemic stroke

Clausen, BH., Lundberg, L., Yli-Karjanmaa, M., Martin, N. A., Svensson, M., Alfsen, Lyngsø, K., Serrano, AB., Nielsen, H. H., Hansen, PB., Finsen, B., Deierborg, T., Illés, Z. & Lambertsen, K. L., 26. Sep 2016.

Research output: Contribution to conference without publisher/journalPosterResearch

Fumaric acid for derivatives for medical use

Illés, Z., Lambertsen, K. L., Finsen, B., Nielsen, H. H. & Clausen, B. H., 19. May 2016, Patent No. WO2016074684 (A1), 19. May 2016, Priority date 11. Nov 2014, Priority No. US201462078051P

Research output: Patent

Functional effect of FGF2- and FGF8-expanded ventral mesencephalic precursor cells in a rat model of Parkinson's disease

Jensen, P., Pedersen, E. A., Zimmer, J. & Meyer, M., 2008, In : Brain Research. 1218, p. 13-20

Research output: Contribution to journalJournal articleResearchpeer-review

Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis

Leth-Larsen, R., Terp, M. G., Christensen, A. G. L., Elias, D., Kühlwein, T., Jensen, O. N., Petersen, O. W. & Ditzel, H., 2012, In : Molecular Medicine. 18, p. 1109-1121 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia

Dionne, N., Dib, S., Finsen, B., Denarier, E., Kuhlmann, T., Drouin, R., Kokoeva, M., Hudson, T. J., Siminovitch, K., Friedman, H. C. & Peterson, A. C., Jan 2016, In : Glia. 64, 1, p. 175–194

Research output: Contribution to journalJournal articleResearchpeer-review

Function of the Nkx2.2 transcription factor in oligodendrocytes and their progenitor cells. Glia, Volume 61, Issue Suppl 1, S49.

Finsen, B. & Fenger, C., 2013.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

GABA(A) Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels

Young, S. Z., Platel, J-C., Nielsen, J. V., Jensen, N. A. & Bordey, A., 1. Jan 2010, In : Frontiers in cellular neuroscience. 4, p. 8

Research output: Contribution to journalJournal articleResearchpeer-review

GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination

Corell, M., Wicher, G., Radomska, K. J., Daglikoca, E. D., Godskesen, R. E., Fredriksson, R., Benedikz, E., Magnaghi, V. & Fex Svenningsen, Å., 1. Feb 2015, In : Journal of Neuroscience Research. 93, 2, p. 285-295 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Gamma-secretase activity of presenilin 1 regulates acetylcholine muscarinic receptor-mediated signal transduction

Popescu, B. O., Cedazo-Minguez, A., Benedikz, E., Nishimura, T., Winblad, B., Ankarcrona, M. & Cowburn, R. F., 2004, In : Journal of Biological Chemistry. 279, 8, p. 6455-64 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures

Bonde, C., Kristensen, B. W., Blaabjerg, M., Johansen, T., Zimmer, J. & Meyer, M., 18. Dec 2000, In : NeuroReport. 11, 18, p. 4069-73 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

GDNF family ligands display distinct action profiles on cultured GABAergic and serotonergic neurons of rat ventral mesencephalon.

Ducray, A., Krebs, S. H., Schaller, B., Seiler, R. W., Meyer, M. & Widmer, H. R., 19. Jan 2006, In : Brain Research. 1069, 1, p. 104-112 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

GDNF pre-treatment aggravates neuronal cell loss in oxygen-glucose deprived hippocampal slice cultures: A possible effect of glutamate transporter upregulation

Bonde, C., Sarup, A., Schousboe, A., Gegelashvili, G., Noraberg, J. & Zimmer, J., 2003, In : Neurochemistry International. 43, 4-5, p. 381-388

Research output: Contribution to journalJournal articleResearch

Gene-environment effects on hippocampal neurodevelopment: Implication for psychiatric illness

Rosenthal, E. H., 15. Jun 2012.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearch

Generation and properties of a new human ventral mesencephalic neural stem cell line

Villa, A., Liste, I., Courtois, E. T., Seiz, E. G., Ramos, M., Meyer, M., Juliusson, B., Kusk, P. & Martínez-Serrano, A., 1. Jul 2009, In : Experimental Cell Research. 315, 11, p. 1860-74 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Generation of human induced pluripotent stem cells (SDUKIi002-A) from a 22-year-old male diagnosed with autism spectrum disorder

Kamand, M., Ilieva, M., Forsberg, S. L., Thomassen, M., Fex Svenningsen, Å., Holst, B., Meyer, M. & Michel, T. M., Jul 2020, In : Stem Cell Research. 46, 4 p., 101834.

Research output: Contribution to journalJournal articleResearchpeer-review

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Gene therapy for glioblastoma [correction of gliobestome] multiform: in vivo tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir.

Stockhammer, G., Brotchi, J., Leblanc, R., Bernstein, M., Schackert, G., Weber, F., Ostertag, C., Mulder, N. H., Mellstedt, H., Seiler, R., Yonekawa, Y., Twerdy, K., Kostron, H., De Witte, O., Lambermont, M., Velu, T., Laneuville, P., Villemure, J. G., Rutka, J. T., Warnke, P. & 6 others, Laseur, M., Mooij, J. J., Boëthius, J., Mariani, L., Gianella-Borradori, A. & Meyer, M., 1. Apr 1997, In : Journal of Molecular Medicine. 75, 4, p. 300-4 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Genetic ablation of soluble TNF does not affect lesion size and functional recovery after moderate spinal cord injury in mice

Ellman, D. G., Degn, M., Lund, M. C., Clausen, B. H., Novrup, H. G., Flæng, S. B., Jørgensen, L. H., Suntharalingam, L., Fex Svenningsen, Å., Brambilla, R. & Lambertsen, K. L., 14. Dec 2016, In : Mediators of Inflammation. 2016, 2684098.

Research output: Contribution to journalJournal articleResearchpeer-review

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Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia

Madsen, P. M., Clausen, B. H., Degn, M., Thyssen, S., Kristensen, L. K., Svensson, M., Ditzel, N., Finsen, B., Deierborg, T., Brambilla, R. & Lambertsen, K. L., 1. Sep 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 9, p. 1553-1569

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Genetic deletion of the adenosine A(2A) receptor prevents nicotine-induced upregulation of alpha 7, but not alpha 4 beta 2*nicotinic acetylcholine receptor binding in the brain

Metaxas, A., Al-Hasani, R., Farshim, P., Tubby, K., Berwick, A., Ledent, C., Hourani, S., Kitchen, I. & Bailey, A., 2013, In : Neuropharmacology.

Research output: Contribution to journalJournal articleResearchpeer-review

Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels

Lambertsen, K. L., Gramsbergen, J. B., Sivasaravanaparan, M., Ditzel, N., Møller, L. M. S., Oliván-Viguera, A., Rabjerg, M., Wulff, H. & Köhler, R., 2012, In : P L o S One. 7, 10, p. e47744

Research output: Contribution to journalJournal articleResearchpeer-review

Genetic Manipulations of EAE in the Mouse

Zehntner, S. P. & Owens, T., 2008, Multiple sclerosis: a comprehensive text. Raine, C. S., McFarland, H. F. & Hohlfeld, R. (eds.). Edinburgh: Pergamon Press, p. 259-271

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Genetic models for CNS inflammation.

Owens, T., Wekerle, H. & Antel, J., 1. Feb 2001, In : Nature Medicine. 7, 2, p. 161-6 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Genome-wide association study of seasonal affective disorder

Ho, K. W. D., Han, S., Nielsen, J. V., Jancic, D., Hing, B., Fiedorowicz, J., Weissman, M. M., Levinson, D. F. & Potash, J. B., 14. Sep 2018, In : Translational Psychiatry. 8, 8 p., 190.

Research output: Contribution to journalJournal articleResearchpeer-review

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Glial cell line-derived neurotrophic factor up-regulates GTP-cyclohydrolase I activity and tetrahydrobiopterin levels in primary dopaminergic neurones.

Bauer, M., Suppmann, S., Meyer, M., Hesslinger, C., Gasser, T., Widmer, H. R. & Ueffing, M., 1. Sep 2002, In : Journal of Neurochemistry. 82, 5, p. 1300-10 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glial membranes at the node of Ranvier prevent neurite outgrowth

Huang, J. K., Phillips, G. R., Roth, A. D., Pedraza, L., Shan, W., Belkaid, W., Mi, S., Svenningsen, Å. F., Florens, L., Yates, J. R. & Colman, D. R., 2005, In : Science. 310, 5755, p. 1813-7 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis

Hardin-Pouzet, H., Krakowski, M., Bourbonnière, L., Didier-Bazes, M., Tran, E. & Owens, T., 1. May 1997, In : Glia. 20, 1, p. 79-85 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glutamate receptor antagonists and growth factors modulate dentate granule cell neurogenesis in organotypic, rat hippocampal slice cultures.

Poulsen, F. R., Blaabjerg, M., Montero, M. & Zimmer, J., 27. Jul 2005, In : Brain Research. 1051, 1-2, p. 35-49 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

Bøttger, P., Glerup, S., Gesslein, B., Illarionova, N. B., Isaksen, T. J., Heuck, A., Clausen, B. H., Füchtbauer, E-M., Gramsbergen, J. B., Gunnarson, E., Aperia, A., Lauritzen, M., Lambertsen, K. L., Nissen, P. & Lykke-Hartmann, K., 25. Feb 2016, In : Scientific Reports. 6, 21 p., 22047.

Research output: Contribution to journalJournal articleResearchpeer-review

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Group I Metabotropic Glutamate Receptors: A Potential Target for Regulation of Proliferation and Differentiation of an Immortalized Human Neural Stem Cell Line

Erichsen, J. L., Blaabjerg, M., Bogetofte Thomasen, H., Serrano, A. M. & Meyer, M., Apr 2015, In : Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 329-336

Research output: Contribution to journalJournal articleResearchpeer-review