Research Output

Characterizing disease-associated changes in post-translational modifications by mass spectrometry

Thygesen, C., Boll, I., Finsen, B., Modzel, M. & Larsen, M. R., 2018, In : Expert Review of Proteomics. 15, 3, p. 245-258

Research output: Contribution to journalReviewResearchpeer-review

Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS.

Babcock, A. A., Kuziel, W. A., Rivest, S. & Owens, T., 27. Aug 2003, In : Journal of Neuroscience. 23, 21, p. 7922-30 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis.

Glabinski, A. R., Krakowski, M., Han, Y., Owens, T. & Ransohoff, R. M., 1. Feb 1999, In : Journal of NeuroVirology. 5, 1, p. 95-101 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chemokine receptor expression by inflammatory T cells in EAE

Mony, J. T., Khorooshi, R. & Owens, T., 2014, In : Frontiers in cellular neuroscience. 8, 9 p., 187.

Research output: Contribution to journalJournal articleResearchpeer-review

Chemokines in Autoimmune Demyelination

Fux, M., Millward, J. & Owens, T., 2008, Central Nervous System Diseases and Inflammation. Lane, T. E., Carson, M., Bergmann, C. & Wyss-Coray, T. (eds.). New York: Springer Science+Business Media, p. 175-201

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Chemokines in experimental autoimmune encephalomyelitis and multiple sclerosis.

Babcock, A. & Owens, T., 1. Jan 2003, In : Advances in Experimental Medicine and Biology. 520, p. 120-32 12 p.

Research output: Contribution to journalReviewResearch

Chronic, systemic LPS treatment reduces cortical Aβ levels in APP/PS1 Tg mice of two backgrounds

Thygesen, C., 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Chronic lipopolysaccharide treatment affects cerebral amyloidosis and pathways of inflammation and synaptic plasticity in an APP/PS1 mouse model of Alzheimer's disease"

Ilkjær, L., Thygesen, C., Babcock, A., Kempf, S. & Finsen, B., 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Cladribine modifies functional properties of murine microglia

Jorgensen, L., Hyrlov, K. H., Elkjaer, M. L., Pedersen, A. E., Svenningsen, A. F. & Illes, Z., 1. Sep 2019, In : Multiple Sclerosis Journal. 25, 2 Suppl. 1, p. 527 1 p., P997.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Clinically stable disease is associated with a lower risk of both income loss and disability pension for patients with multiple sclerosis

Chalmer, T. A., Buron, M., Illes, Z., Papp, V., Theodorsdottir, A., Schäfer, J., Hansen, V., Asgari, N., Skejø, P. B., Jensen, H. B., Sørensen, P. S. & Magyari, M., Jan 2020, In : Journal of Neurology, Neurosurgery and Psychiatry. 91, 1, p. 67-74

Research output: Contribution to journalJournal articleResearchpeer-review

Clinically Suspected Cast Nephropathy: A Retrospective, Multi-Center, Real-World Study

Szabo, A. G., Thorsen, J., Hansen, C. T., Vase, M. Ø., Teodorescu, M., Pedersen, S. B., Flæng, S. B., Frølund, U. C., Vangsted, A. J. & Plesner, T., 13. Nov 2019, In : Blood. 134, Suppl. 1, p. 5553-5553 1 p.

Research output: Contribution to journalConference abstract in journalResearch

CLIPPERS among patients diagnosed with non-specific CNS neuroinflammatory diseases

Kerrn-Jespersen, B. M., Lindelof, M., Illes, Z., Blaabjerg, M., Lund, E. L., Klausen, C., Christiansen, I., Sellebjerg, F. & Kondziella, D., 15. Aug 2014, In : Journal of the Neurological Sciences. 343, 1-2, p. 224-7

Research output: Contribution to journalJournal articleResearchpeer-review

CLIPPERS as a differential diagnosis to multiple sclerosis: evidence from pathology and 7T MRI

Blaabjerg, M., Ruprech, K., Sinnecker, T., Kondziella, D., Niendorf, T., Kerrn-Jespersen, B. M., Lindelof, M., Lassmann, H., Kristensen, B. W., Paul, F. & Illes, Z., 2015, In : Multiple Sclerosis Journal. 21, 11 suppl, p. 370 1 p., P745.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

CLIPPERS as a differential diagnosis to multiple sclerosis: evidence from pathology and 7T MRI

Blaabjerg, M., Ruprecht, K., Sinnecker, T., Kondziella, D., Niendorf, T., Kern-Jespersen, BM., Lindelof, M., Lassmann, H., Kristensen, B. W., Paul, F. & Illés, Z., 7. Oct 2015.

Research output: Contribution to conference without publisher/journalPosterResearch

Cloning and expression of the human N-methyl-D-aspartate receptor subunit NR3A

Eriksson, M., Nilsson, A., Froelich-Fabre, S., Akesson, E., Dunker, J., Seiger, A., Folkesson, R., Benedikz, E. & Sundström, E., 2002, In : Neuroscience Letters. 321, 3, p. 177-81 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation

Owens, T., Fazekas de St Groth, B. & Miller, J. F., 1. Dec 1987, In : Proceedings of the National Academy of Science of the United States of America. 84, 24, p. 9209-13 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Colchicine induces apoptosis in organotypic hippocampal slice cultures

Kristensen, B. W., Noer, H., Gramsbergen, J. B., Zimmer, J. & Noraberg, J., 28. Feb 2003, In : Brain Research. 964, 2, p. 264-78 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD

Cook, L. J., Rose, J. W., Alvey, J. S., Jolley, A. M., Kuhn, R., Marron, B., Pederson, M., Enriquez, R., Yearley, J., McKechnie, S., Han, M. H., Tomczak, A. J., Levy, M., Mealy, M. A., Coleman, J., Bennett, J. L., Johnson, R., Barnes-Garcia, M., Traboulsee, A. L., Carruthers, R. L. & 42 others, Lee, L. E., Schubert, J. J., McMullen, K., Kister, I., Rimler, Z., Reid, A., Sicotte, N. L., Planchon, S. M., Cohen, J. A., Ivancic, D., Sedlak, J. L., Sand, I. K., Repovic, P., Amezcua, L., Pruitt, A., Amundson, E., Chitnis, T., Mullin, D. S., Klawiter, E. C., Russo, A. W., Riley, C. S., Onomichi, K. B., Levine, L., Nelson, K. E., Nealon, N. M., Engel, C., Kruse-Hoyer, M., Marcille, M., Tornes, L., Rumpf, A., Greer, A., Behne, M. K., Rodriguez, R. R., Behne, D. W., Blackway, D. W., Coords, B., Blaschke, T. F., Sheard, J., Smith, T. J., Behne, J. M., Yeaman, M. R. & The Guthy-Jackson Charitable Foundation International Clinical Consortium (GJCF–ICC), Sep 2019, In : Neurology: Neuroimmunology & Neuroinflammation. 6, 5, 17 p., e583.

Research output: Contribution to journalJournal articleResearchpeer-review

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Comparative analysis of spontaneous and stimulus-evoked calcium transients in proliferating and differentiating human midbrain-derived stem cells

Johansen, T., Krabbe, C., Schmidt, S. I., Martinez-Serrano, A. & Meyer, M., 22. Oct 2017, In : Stem Cells International. 2017, 14 p., 9605432.

Research output: Contribution to journalJournal articleResearchpeer-review

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Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures

Kristensen, B. W., Noraberg, J. & Zimmer, J., 2001, In : Brain Research. 917, 1, p. 21-44 24 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparison of mesencephalic free-floating tissue culture grafts and cell suspension grafts in the 6-hydroxydopamine-lesioned rat

Meyer, M., Widmer, H. R., Wagner, B., Guzman, R., Evtouchenko, L., Seiler, R. W. & Spenger, C., 1. Apr 1998, In : Experimental Brain Research. 119, 3, p. 345-55 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparison of microglia and infiltrating CD11c+ cells as antigen presenting cells for T cell proliferation and cytokine response

Wlodarczyk, A., Løbner, M., Cédile, O. & Owens, T., 25. Mar 2014, In : Journal of Neuroinflammation. 11, 1, 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures

Montero, M., Rom Poulsen, F., Noraberg, J., Kirkeby, A., van Beek, J., Leist, M. & Zimmer, J., 1. Mar 2007, In : Experimental Neurology. 204, 1, p. 106-117 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparison of the efficacy of azathioprine and rituximab in neuromyelitis optica spectrum disorder: a randomized clinical trial

Nikoo, Z., Badihian, S., Shaygannejad, V., Asgari, N. & Ashtari, F., 22. Aug 2017, In : Journal of Neurology. 264, 9, p. 2003-2009

Research output: Contribution to journalJournal articleResearchpeer-review

Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid

Asgari, N., Khorooshi, R., Lillevang, S. T. & Owens, T., 15. Jan 2013, In : Journal of Neuroimmunology. 254, 1-2, p. 76-82

Research output: Contribution to journalJournal articleResearchpeer-review

Compromised epidermal barrier stimulates Harderian gland activity and hypertrophy in ACBP-/- mice

Sørensen, S. B., Neess, D., Dixen, K., Bloksgaard, M., Marcher, A-B., Chemnitz, J., Færgeman, N. J. & Mandrup, S., Sep 2015, In : Journal of Lipid Research. 56, 9, p. 1738-1746 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling

Clausen, B. H., Degn, M., Sivasaravanaparan, M., Fogtmann, T., Andersen, M. G., Trojanowsky, M. D., Gao, H., Hvidsten, S., Baun, C., Deierborg, T., Finsen, B., Kristensen, B. W., Bak, S. T., Meyer, M., Lee, J., Nedospasov, S. A., Brambilla, R. & Lambertsen, K. L., 7. Jul 2016, In : Scientific Reports. 6, 16 p., 29291.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death.

Hollmann, C. A., Owens, T., Nalbantoglu, J., Hudson, T. J. & Sladek, R., 1. Apr 2006, In : Cancer Research. 66, 7, p. 3550-7 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Constitutive expression of a costimulatory ligand on antigen-presenting cells in the nervous system drives demyelinating disease.

Zehntner, S. P., Brisebois, M., Tran, E., Owens, T. & Fournier, S., 1. Oct 2003, In : The FASEB Journal. 17, 13, p. 1910-2 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis.

Kuhlmann, T., Remington, L., Cognet, I., Bourbonniere, L., Zehntner, S., Guilhot, F., Herman, A., Guay-Giroux, A., Antel, J. P., Owens, T. & Gauchat, J-F., 1. Aug 2006, In : American Journal of Pathology. 169, 2, p. 584-98 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Contralesional hindlimb motor response induced by unilateral brain injury: evidence for extra spinal mechanism

Bakalkin, G., Carvalho, L., Watanabe, H., Zhang, M., Sarkisyan, D., Kononenko, O., Bazov, I., Iakovleva, T., Schouenborg, J. & Lukoyanov, N., 2018. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Convection-enhanced delivery of an anti-miR is well-tolerated, preserves anti-miR stability and causes efficient target de-repression: a proof of concept

Halle, B., Marcusson, E. G., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Schulz, M. K., Andersen, C. & Kristensen, B. W., 2016, In : Journal of Neuro-Oncology. 126, 1, p. 47-55

Research output: Contribution to journalJournal articleResearchpeer-review

Corrigendum to “Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9transgenic mice: Effect of long-term treatment with paroxetine" [Neurobiol Dis. 2017; 104: 50-60].

Olesen, LØ., Sivasaravanaparan, M., Severino, M., Babcock, A. A., Bouzinova, E. V., West, M. J., Wiborg, O. & Finsen, B., Apr 2019, In : Neurobiology of Disease. 124, p. 573

Research output: Contribution to journalComment/debateResearchpeer-review

Cortical morphogenesis during embryonic development is regulated by miR-34c and miR-204

Venø, M. T., Venø, S. T., Rehberg, K., van Asperen, J. V., Clausen, B. H., Holm, I. E., Pasterkamp, R. J., Finsen, B. & Kjems, J., 2017, In : Frontiers in Molecular Neuroscience. 10, 10 p., 31.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Co-stimulation by anti-immunoglobulin is required for B cell activation by CD40Llow T cells

Poudrier, J. & Owens, T., 1. Dec 1994, In : European Journal of Immunology. 24, 12, p. 2993-9 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Coupling of organotypic brain slice cultures to silicon-based arrays of electrodes

Jahnsen, H., Kristensen, B. W., Thiébaud, P., Noraberg, J., Jakobsen, B., Bove, M., Martinoia, S., Koudelka-Hep, M., Grattarola, M. & Zimmer, J., 1. Jun 1999, In : Methods. 18, 2, p. 160-72 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Creation of a library of induced pluripotent stem cells from Parkinsonian patients

Holmqvist, S., Lehtonen, S., Chumarina, M., Puttonen, K., Azevedo, C., Lebedeva, O., Ruponen, M., Oksanen, M., Djelloul, M., Collin, A., Goldwurm, S., Meyer, M., Lagarkova, M., Kiselev, S., Koistinaho, J. & Roybon, L., 2. Jun 2016, In : n p j Parkinson's Disease. 2, 10 p., 16009.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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CSF1R stimulation promotes increased neuroprotection by CD11c+microglia in EAE

Benmamar-Badel, A., Wlodarczyk, A., Cedile, O., Jensen, K. N., Kramer, I., Elsborg, N. B. & Owens, T., Dec 2019, In : Scandinavian Journal of Immunology. 90, 6, p. 4 1 p., 7.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

Wlodarczyk, A., Benmamar-Badel, A., Cédile, O., Nolling Jensen, K., Kramer, I., Elsborg, N. B. & Owens, T., 10. Jan 2019, In : Frontiers in Cellular Neuroscience. 12, 10 p., 523.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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CSF biomarkers for Parkinson’s disease: Loss of glucocerebrosidase activity and alterations in modified forms of alpha-synuclein

Gramsbergen, J. B., Dammann Andersen, A., Iversen, P., Blaabjerg, M., Binzer, M., Pakkenberg, B., Brudek, T., Heegaard, N. H. H. & Stenager, E., 2017, In : Journal of Neurochemistry. 142, Suppl. 1, p. 108 1 p., MTU04-09.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

CSF catecholamine and kynurenine metabolites in Parkinson's disease and L-DOPA-induced dyskinesia

Dammann Andersen, A., Havelund, J. F., Binzer, M., Blaabjerg, M., Kamal, A., Thagesen, H., Kjær, T. W., Færgeman, N. J., Heegaard, N. H. H., Stenager, E. & Gramsbergen, J. B., 20. Aug 2017, In : Journal of Neurochemistry. 142, Suppl. 1, p. 107 1 p., MTU04-04.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

CSF transthyretin neuroprotection in a mouse model of brain ischemia

Santos, S. D., Lambertsen, K. L., Clausen, B. H., Akinc, A., Alvarez, R., Finsen, B. & Saraiva, M. J., 1. Dec 2010, In : Journal of Neurochemistry. 115, 6, p. 1434-44 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cyclosporin A ameliorates cerebral oxidative metabolism and infarct size in the endothelin-1 rat model of transient cerebral ischaemia

Forsse, A., Nielsen, T. H., Nygaard, K. H., Nordström, C-H., Gramsbergen, J. B. & Poulsen, F. R., 2019, In : Scientific Reports. 9, 1, 3702.

Research output: Contribution to journalJournal articleResearchpeer-review

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Cytokine and chemokine inter-regulation in the inflamed or injured CNS.

Owens, T., Babcock, A. A., Millward, J. M. & Toft-Hansen, H., 1. Apr 2005, In : Brain Research Reviews. 48, 2, p. 178-84 6 p.

Research output: Contribution to journalReviewResearch

Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice

Babcock, A. A., Ilkjær, L., Clausen, B. H., Villadsen, B., Dissing-Olesen, L., Bendixen, A. T. M., Lyck, L., Lambertsen, K. L. & Finsen, B., Aug 2015, In : Brain, Behavior, and Immunity. 48, August, p. 86–101

Research output: Contribution to journalJournal articleResearchpeer-review

Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice

Renno, T., Lin, J. Y., Piccirillo, C., Antel, J. & Owens, T., 1. Jan 1994, In : Journal of Neuroimmunology. 49, 1-2, p. 1-7 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Cytokines in CNS Inflammation

Owens, T., Wheeler, R. D. & Zehntner, S. P., 2005, Cytokines and the CNS. Ransohoff, R. M. & Benveniste, E. N. (eds.). Second Edition ed. Boca Raton, FL, USA: CRC Press, p. 113-136

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Dannelse af nye nerveceller i den voksne hjerne

Translated title of the contribution: Generation of new nerve cells in the adult human brainPoulsen, F. R., Meyer, M. & Rasmussen, J. Z., 2003, In : Ugeskrift for læger. 165, 14, p. 1443-1447

Research output: Contribution to journalJournal articleResearchpeer-review

Decreased interleukin-2 responses to Fusobacterium nucleatum and Porphyromonas gingivalis in generalized aggressive periodontitis

Borch, T. S., Pedersen, M. L., Bendtzen, K., Holmstrup, P. & Nielsen, C. H., 2009, In : Journal of Periodontology. 80, 5, p. 800-7 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review