• J. B. Winsløws Vej 17, 2. sal.

    5000 Odense C

Research Output 1973 2019

2019
2 Downloads (Pure)

A Birth Cohort Study on the Genetic Modification of the Association of Prenatal Methylmercury With Child Cognitive Development

Julvez, J., Smith, G. D., Ring, S. M. & Grandjean, P., 1. Oct 2019, In : American Journal of Epidemiology. 188, 10, p. 1784-1793

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cohort Studies
Mercury
Progesterone Receptors
Single Nucleotide Polymorphism
Alleles

Anogenital distance in children born of mothers with polycystic ovary syndrome: the Odense Child Cohort

Glintborg, D., Jensen, R. C., Schmedes, A. V., Brandslund, I., Kyhl, H. B., Nielsen, T. K. & Andersen, M. S., 2. Oct 2019, In : Human reproduction (Oxford, England). 34, 10, p. 2061-2070

Research output: Contribution to journalJournal articleResearchpeer-review

Polycystic Ovary Syndrome
Mothers
Penis
Denmark
Research

Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population

Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, A., Skakkebaek, N. E., Swan, S. H. & Jørgensen, N., 1. Jan 2019, In : Human reproduction (Oxford, England). 34, 1, p. 12-24

Research output: Contribution to journalJournal articleResearchpeer-review

Hormones
Population
Odds Ratio
Semen
Scrotum

A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24

Mirza, M. R., Bergmann, T. K., Mau-Sørensen, M., Christensen, R. D., Åvall-Lundqvist, E., Birrer, M. J., Jørgensen, M., Roed, H., Malander, S., Nielsen, F., Lassen, U., Brøsen, K., Bjørge, L. & Mäenpää, J., Oct 2019, In : Cancer Chemotherapy and Pharmacology. 84, 4, p. 791-798

Research output: Contribution to journalJournal articleResearchpeer-review

Platinum
Angiogenesis Inhibitors
Germ-Line Mutation
Ovarian Neoplasms
Disease-Free Survival
Open Access
File
Mothers
perfluorooctanoic acid
Endocrine Disruptors
Denmark
Parity

Associations of exposure to perfluoroalkyl substances with thyroid hormone concentrations and birth size

Xiao, C., Grandjean, P., Valvi, D., Nielsen, F., Jensen, T. K., Weihe, P. & Oulhote, Y., 29. Oct 2019, In : The Journal of clinical endocrinology and metabolism.

Research output: Contribution to journalJournal articleResearchpeer-review

perfluorooctanoic acid
Thyrotropin
Thyroid Hormones
Mothers
Linear regression
34 Downloads (Pure)

A strategy to validate a selection of human effect biomarkers using adverse outcome pathways: Proof of concept for phthalates and reproductive effects

Baken, K. A., Lambrechts, N., Remy, S., Mustieles, V., Rodríguez-Carrillo, A., Neophytou, C. M., Olea, N. & Schoeters, G., 2019, In : Environmental Research. 175, p. 235-256

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
phthalate
Biomarkers
biomarker
Peroxisome Proliferator-Activated Receptors
Health

Bone mineral density is preserved in men with idiopathic infertility

Antonio, L., Priskorn, L., Nordkap, L., Bang, A. K., Jensen, T. K., Skakkebæk, N. E., Petersen, J. H., Vanderschueren, D. & Jørgensen, N., 2019, In : Andrology.

Research output: Contribution to journalJournal articleResearchpeer-review

Bone Density
Infertility
Femur Neck
Photon Absorptiometry
Semen

Development priority

Grandjean, P., Prins, G. S. & Weihe, P., Aug 2019, In : Basic & Clinical Pharmacology & Toxicology. 125, S3, p. 3-4

Research output: Contribution to journalEditorialResearchpeer-review

Early life exposures to perfluoroalkyl substances in relation to adipokine hormone levels at birth and during childhood

Shelly, C., Grandjean, P., Oulhote, Y., Plomgaard, P., Frikke-Schmidt, R., Nielsen, F., Zmirou-Navier, D., Weihe, P. & Valvi, D., 1. Nov 2019, In : The Journal of clinical endocrinology and metabolism. 104, 11, p. 5338-5348

Research output: Contribution to journalJournal articleResearchpeer-review

Adipokines
Resistin
Hormones
Adiponectin
Leptin

Endocrine disrupters, semen quality and anogenital distance

Jensen, T. K., Aug 2019, In : Current Opinion in Endocrine and Metabolic Research. 7, p. 34-42

Research output: Contribution to journalReviewResearchpeer-review

Maternal Exposure
Chlorinated Hydrocarbons
Endocrine Disruptors
Reproductive Health
Meta-Analysis
48 Downloads (Pure)

Environmental chemical exposures among Greenlandic children in relation to diet and residence

Timmermann, C. A. G., Pedersen, H. S., Budtz-Jørgensen, E., Bjerregaard, P., Oulhote, Y., Weihe, P., Nielsen, F. & Grandjean, P., Dec 2019, In : International Journal of Circumpolar Health. 78, 1, 11 p., 1642090.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Environmental Exposure
Diet
Proxy
Mercury
Linear Models

Fish Consumption During Pregnancy

Grandjean, P., Lederman, S. A. & Silbergeld, E. K., 1. Mar 2019, In : JAMA Pediatrics. 173, 3

Research output: Contribution to journalJournal articleResearch

18 Downloads (Pure)

Gender differences in cognitive performance and health status in the Faroese Septuagenarians cohort

Petersen, M. S., Debes, F., Grandjean, P. & Weihe, P., Feb 2019, In : European Journal of Public Health. 29, 1, p. 79–81

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Joint Diseases
Myalgia
Cross-Sectional Studies
Health
Surveys and Questionnaires

Hair cortisol in newly diagnosed bipolar disorder and unaffected first-degree relatives

Coello, K., Munkholm, K., Nielsen, F., Vinberg, M. & Kessing, L. V., Jan 2019, In : Psychoneuroendocrinology. 99, p. 183-190

Research output: Contribution to journalJournal articleResearchpeer-review

Hair
Wounds and Injuries

Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors

Shaffer, R. M., Sellers, S. P., Baker, M. G., de Buen Kalman, R., Frostad, J., Suter, M. K., Anenberg, S. C., Balbus, J., Basu, N., Bellinger, D. C., Birnbaum, L., Brauer, M., Cohen, A., Ebi, K. L., Fuller, R., Grandjean, P., Hess, J. J., Kogevinas, M., Kumar, P., Landrigan, P. J. & 7 others, Lanphear, B., London, S. J., Rooney, A. A., Stanaway, J. D., Trasande, L., Walker, K. & Hu, H., Oct 2019, In : Environmental Health Perspectives. 127, 10, p. 105001-1-105001-16

Research output: Contribution to journalJournal articleResearchpeer-review

Environmental Health
Air Pollution
Health
Endocrine Disruptors
Premature Mortality

Mothers and children are related, even in exposure to chemicals present in common consumer products

Koppen, G., Govarts, E., Vanermen, G., Voorspoels, S., Govindan, M., Dewolf, M. C., Den Hond, E., Biot, P., Casteleyn, L., Kolossa-Gehring, M., Schwedler, G., Angerer, J., Koch, H. M., Schindler, B. K., Castaño, A., López, M. E., Sepai, O., Exley, K., Bloemen, L., Knudsen, L. E. & 4 others, Joas, R., Joas, A., Schoeters, G. & Covaci, A., Aug 2019, In : Environmental Research. 175, p. 297-307

Research output: Contribution to journalJournal articleResearchpeer-review

Consumer products
phthalate
Triclosan
Mothers
Dibutyl Phthalate

Perfluorinated substances, risk factors for multiple sclerosis and cellular immune activation

Ammitzbøll, C., Börnsen, L., Petersen, E. R., Oturai, A. B., Søndergaard, H. B., Grandjean, P. & Sellebjerg, F., 15. May 2019, In : Journal of Neuroimmunology. 330, p. 90-95

Research output: Contribution to journalJournal articleResearchpeer-review

Smoking
perfluorooctane sulfonic acid

Perfluoroalkyl substances and changes in bone mineral density: A prospective analysis in the POUNDS-LOST study

Hu, Y., Liu, G., Rood, J., Liang, L., Bray, G. A., de Jonge, L., Coull, B., Furtado, J. D., Qi, L., Grandjean, P. & Sun, Q., 2019, In : Environmental Research. 179, 7 p., 108775.

Research output: Contribution to journalJournal articleResearchpeer-review

Bone Density
Minerals
bone
Bone
Hip
1 Downloads (Pure)

Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances

Eryasa, B., Grandjean, P., Nielsen, F., Valvi, D., Zmirou-Navier, D., Sunderland, E., Weihe, P. & Oulhote, Y., Sep 2019, In : Environment International. 130, p. 104874

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
diabetes
chemical property
partitioning
blood
serum
Adiposity
Adipose Tissue
Cohort Studies
Mothers
Linear Models

Prenatal bisphenol A exposure is associated with language development but not with ADHD-related behavior in toddlers from the Odense Child Cohort

Jensen, T. K., Mustieles, V., Bleses, D., Frederiksen, H., Trecca, F., Schoeters, G., Andersen, H. R., Grandjean, P., Kyhl, H. B., Juul, A., Bilenberg, N. & Andersson, A. M., 1. Mar 2019, In : Environmental Research. 170, p. 398-405

Research output: Contribution to journalJournal articleResearchpeer-review

Mothers
urine
Urine
breastfeeding
fasting
48 Downloads (Pure)

Prevalence of prediabetes and type 2 diabetes in two non-random populations aged 44–77 years in the Faroe Islands

Veyhe, A. S., Andreassen, J., Halling, J., Grandjean, P., Skaalum Petersen, M. & Weihe, P., Jun 2019, In : Journal of Clinical and Translational Endocrinology. 16, 8 p., 100187.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Prediabetic State
Denmark
Type 2 Diabetes Mellitus
Population
Fasting
2 Downloads (Pure)

Response to Juberg et al

Mie, A., Rudén, C. & Grandjean, P., 2019, In : Environmental Health. 18, 3 p., 29.

Research output: Contribution to journalLetterResearch

Open Access
File
44 Downloads (Pure)

Tap water contributions to plasma concentrations of poly- and perfluoroalkyl substances (PFAS) in a nationwide prospective cohort of U.S. women

Hu, X. C., Tokranov, A. K., Liddie, J., Zhang, X., Grandjean, P., Hart, J. E., Laden, F., Sun, Q., Yeung, L. W. Y. & Sunderland, E. M., Jun 2019, In : Environmental Health Perspectives. 127, 6, 11 p., 067006.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
perfluorooctanoic acid
Nurses
United States Environmental Protection Agency
Fluorine
Water Supply
Registries
Twin Studies
Denmark
Polycystic Ovary Syndrome
Third Pregnancy Trimester
Mothers
Cortisone
Fasting
21 Downloads (Pure)

Time scales of developmental toxicity impacting on research and needs for intervention

Grandjean, P., Abdennebi-Najar, L., Barouki, R., Cranor, C. F., Etzel, R. A., Gee, D., Heindel, J. J., Hougaard, K. S., Hunt, P., Nawrot, T. S., Prins, G. S., Ritz, B., Soffritti, M., Sunyer, J. & Weihe, P., Aug 2019, In : Basic & Clinical Pharmacology & Toxicology. 125, Suppl. 3, p. 70-80

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Toxicity
Research
Health
Computational chemistry
Epidemiology
2018

Accelerated functional losses in ageing congenital Minamata disease patients

Yorifuji, T., Takaoka, S. & Grandjean, P., 10. Aug 2018, In : Neurotoxicology and Teratology. 69, p. 49-53

Research output: Contribution to journalJournal articleResearchpeer-review

Nervous System Mercury Poisoning
Aging of materials
Cognition
Cerebral Palsy
Poisoning

Anogenital distance as a phenotypic signature through infancy

Priskorn, L., Petersen, J. H., Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, K. M., Andersson, A-M., Skakkebaek, N. E. & Jensen, T. K., Mar 2018, In : Pediatric Research. 83, 3, p. 573–579

Research output: Contribution to journalJournal articleResearchpeer-review

Clitoris
Scrotum
Penis
Equidae
Pediatrics
95 Downloads (Pure)

A novel inverse association between cord 25-hydroxyvitamin D and leg length in boys up to three years: An Odense Child Cohort study

Christensen, M. E., Beck-Nielsen, S. S., Dalgård, C., Larsen, S. D., Lykkedegn, S., Kyhl, H. B., Husby, S. & Christesen, H. T., 1. Jun 2018, In : PLOS ONE. 13, 6, 17 p., e0198724.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
cohort studies
Leg
legs
Cohort Studies
rickets
66 Downloads (Pure)

Application of benchmark analysis for mixed contaminant exposures: Mutual adjustment of perfluoroalkylate substances associated with immunotoxicity

Budtz-Jørgensen, E. & Grandjean, P., 2018, In : PLOS ONE. 13, 10, 14 p., e0205388.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
immunotoxicity
Benchmarking
Impurities
Antibodies
dosage
96 Downloads (Pure)
Open Access
File
Maternal Exposure
Pyrethrins
2,4-Dichlorophenoxyacetic Acid
Organophosphates
Herbicides
61 Downloads (Pure)

A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission

Audouze, K., Taboureau, O. & Grandjean, P., Sep 2018, In : Toxicology and Applied Pharmacology. 354, p. 56-63

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
pyriproxyfen
Systems Biology
Viruses
Microcephaly
Toxicity

Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years

Priskorn, L., Nordkap, L., Bang, A. K., Krause, M., Holmboe, S. A., Egeberg Palme, D. L., Winge, S. B., Mørup, N., Carlsen, E., Joensen, U. N., Blomberg Jensen, M., Main, K. M., Juul, A., Skakkebaek, N. E., Jensen, T. K. & Jørgensen, N., 1. Jun 2018, In : Human Reproduction. 33, 6, p. 998-1008

Research output: Contribution to journalJournal articleResearchpeer-review

Cross-Sectional Studies
Smoking
Mothers
Maternal Exposure
Semen
62 Downloads (Pure)

Blood pressure in 3-year-old girls associates inversely with umbilical cord serum 25-hydroxyvitamin D: an Odense Child Cohort study

Larsen, S. D., Dalgård, C., Christensen, M. E., Lykkedegn, S., Andersen, L. B., Andersen, M., Glintborg, D. & Christesen, H. T., 1. Oct 2018, In : Endocrine Connections. 7, 12, p. 1236–1244

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Umbilical Cord
Cohort Studies
Serum
25-Hydroxyvitamin D 2
Mothers
91 Downloads (Pure)

Can profiles of poly- and Perfluoroalkyl substances (PFASs) in human serum provide information on major exposure sources?

Hu, X. C., Dassuncao, C., Zhang, X., Grandjean, P., Weihe, P., Webster, G. M., Nielsen, F. & Sunderland, E. M., 1. Feb 2018, In : Environmental Health: A Global Access Science Source. 17, 15 p., 11.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Serum
Seafood
perfluorooctanoic acid
Population
Health
104 Downloads (Pure)

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

Felix, J. F., Joubert, B. R., Baccarelli, A. A., Sharp, G. C., Almqvist, C., Annesi-Maesano, I., Arshad, H., Baïz, N., Bakermans-Kranenburg, M. J., Bakulski, K. M., Binder, E. B., Bouchard, L., Breton, C. V., Brunekreef, B., Brunst, K. J., Burchard, E. G., Bustamante, M., Chatzi, L., Cheng Munthe-Kaas, M., Corpeleijn, E. & 104 others, Czamara, D., Dabelea, D., Davey Smith, G., De Boever, P., Duijts, L., Dwyer, T., Eng, C., Eskenazi, B., Everson, T. M., Falahi, F., Fallin, M. D., Farchi, S., Fernandez, M. F., Gao, L., Gaunt, T. R., Ghantous, A., Gillman, M. W., Gonseth, S., Grote, V., Gruzieva, O., Håberg, S. E., Herceg, Z., Hivert, M-F., Holland, N., Holloway, J. W., Hoyo, C., Hu, D., Huang, R-C., Huen, K., Järvelin, M-R., Jima, D. D., Just, A. C., Karagas, M. R., Karlsson, R., Karmaus, W., Kechris, K. J., Kere, J., Kogevinas, M., Koletzko, B., Koppelman, G. H., Küpers, L. K., Ladd-Acosta, C., Lahti, J., Lambrechts, N., Langie, S. A. S., Lie, R. T., Liu, A. H., Magnus, M. C., Magnus, P., Maguire, R. L., Marsit, C. J., McArdle, W., Melén, E., Melton, P., Murphy, S. K., Nawrot, T. S., Nisticò, L., Nohr, E. A., Nordlund, B., Nystad, W., Oh, S. S., Oken, E., Page, C. M., Perron, P., Pershagen, G., Pizzi, C., Plusquin, M., Raikkonen, K., Reese, S. E., Reischl, E., Richiardi, L., Ring, S., Roy, R. P., Rzehak, P., Schoeters, G., Schwartz, D. A., Sebert, S., Snieder, H., Sørensen, T. I. A., Starling, A. P., Sunyer, J., Taylor, J. A., Tiemeier, H., Ullemar, V., Vafeiadi, M., Van Ijzendoorn, M. H., Vonk, J. M., Vriens, A., Vrijheid, M., Wang, P., Wiemels, J. L., Wilcox, A. J., Wright, R. J., Xu, C-J., Xu, Z., Yang, I. V., Yousefi, P., Zhang, H., Zhang, W., Zhao, S., Agha, G., Relton, C. L., Jaddoe, V. W. V. & London, S. J., 1. Feb 2018, In : International Journal of Epidemiology. 47, 1, p. 22–23u

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
84 Downloads (Pure)

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Fritsche, E., Grandjean, P., Crofton, K. M., Aschner, M., Goldberg, A., Heinonen, T., Hessel, E. V. S., Hogberg, H. T., Bennekou, S. H., Lein, P. J., Leist, M., Mundy, W. R., Paparella, M., Piersma, A. H., Sachana, M., Schmuck, G., Solecki, R., Terron, A., Monnet-Tschudi, F., Wilks, M. F. & 3 others, Witters, H., Zurich, M-G. & Bal-Price, A., Sep 2018, In : Toxicology and Applied Pharmacology. 354, p. 3-6

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
Consensus
Innovation
Needs Assessment
Environmental Exposure
Testing
Cohort Studies
Serum
Gestational Age
Cranial Fontanelles
25-hydroxyvitamin D
87 Downloads (Pure)
Open Access
File
Environmental Health
Health
Publications
Immune System
Public Health
86 Downloads (Pure)

Dermal uptake and percutaneous penetration of organophosphate esters in a human skin ex vivo model

Frederiksen, M., Stapleton, H. M., Vorkamp, K., Webster, T. F., Jensen, N. M., Sørensen, J. A., Nielsen, F., Knudsen, L. E., Sørensen, L. S., Clausen, P. A. & Nielsen, J. B., Apr 2018, In : Chemosphere. 197, p. 185-192

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
organophosphate
ester
skin
penetration
phosphate

Epigenetics as a mechanism linking developmental exposures to long-term toxicity

Barouki, R., Melén, E., Herceg, Z., Beckers, J., Chen, J., Karagas, M., Puga, A., Xia, Y., Chadwick, L., Yan, W., Audouze, K., Slama, R., Heindel, J., Grandjean, P., Kawamoto, T. & Nohara, K., May 2018, In : Environment International. 114, p. 77-86 10 p.

Research output: Contribution to journalReviewResearchpeer-review

toxicity
health and disease
endocrine disruptor
methylation
smoking

Forskere og universiteter bløder, mens forlagene skummer fløden

Dorch, B. F. & Grandjean, P., 22. Sep 2018

Research output: Other contributionNet publication - Internet publicationCommunication

Open Access

Gestational Diabetes Mellitus: Does One Size Fit All? A Challenge to Uniform Worldwide Diagnostic Thresholds

McIntyre, H. D., Jensen, D. M., Jensen, R. C., Kyhl, H. B., Jensen, T. K., Glintborg, D. & Andersen, M., Jul 2018, In : Diabetes Care. 41, 7, p. 1339-1342

Research output: Contribution to journalJournal articleResearchpeer-review

Gestational Diabetes
Fasting
Pregnancy Complications
Denmark
Cohort Studies
75 Downloads (Pure)

GLI2 promoter hypermethylation in saliva of children with a respiratory allergy

Langie, S. A. S., Moisse, M., Szarc Vel Szic, K., Van Der Plas, E., Koppen, G., De Prins, S., Louwies, T., Nelen, V., Van Camp, G., Lambrechts, D., Schoeters, G., Vanden Berghe, W. & De Boever, P., 11. Apr 2018, In : Clinical Epigenetics (Print). 10, 13 p., 50.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Saliva
Hypersensitivity
DNA Methylation
Genetic Markers
Epigenomics

Health Status of Workers Exposed to Perfluorinated Alkylate Substances

Grandjean, P., Oct 2018, In : Journal of occupational and environmental medicine . 60, 10, p. e562 1 p.

Research output: Contribution to journalComment/debateResearch

100 Downloads (Pure)

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, A. L., Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, B., Antignac, J-P., Le Bizec, B., Platel, C., Hay-Schmidt, A., Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, K., Brunak, S., Kjaer, M., Juul, A. & Jégou, B., 23. Jan 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. E715-E724

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hypogonadism
Ibuprofen
Luteinizing Hormone
Western World
Endocrine System

Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort

Leung, Y-K., Ouyang, B., Niu, L., Xie, C., Ying, J., Medvedovic, M., Chen, A., Weihe, P., Valvi, D., Grandjean, P. & Ho, S-M., 4. Mar 2018, In : Epigenetics. 13, 3, p. 290-300

Research output: Contribution to journalJournal articleResearchpeer-review

Dichlorodiphenyl Dichloroethylene
DNA Methylation
Fetal Blood
Hexachlorobenzene
Chlorinated Hydrocarbons