• J. B. Winsløws Vej 17, 2. sal.

    5000 Odense C

Research Output 1973 2020

2020

Associations of exposure to perfluoroalkyl substances with thyroid hormone concentrations and birth size

Xiao, C., Grandjean, P., Valvi, D., Nielsen, F., Jensen, T. K., Weihe, P. & Oulhote, Y., Mar 2020, In : The Journal of clinical endocrinology and metabolism. 105, 3, 11 p., dgz147.

Research output: Contribution to journalJournal articleResearchpeer-review

perfluorooctanoic acid
Thyrotropin
Thyroid Hormones
Mothers
Linear regression

Associations of Fish Oil Supplement Use With Testicular Function in Young Men

Jensen, T. K., Priskorn, L., Holmboe, S. A., Nassan, F. L., Andersson, A-M., Dalgård, C., Petersen, J. H., Chavarro, J. E. & Jørgensen, N., 3. Jan 2020, In : JAMA Network Open. 3, 1, p. e1919462

Research output: Contribution to journalJournal articleResearchpeer-review

Fish Oils
Follicle Stimulating Hormone
Luteinizing Hormone
Semen
Fatty Acids

Associations of Perfluoroalkyl substances with blood lipids and Apolipoproteins in lipoprotein subspecies: the POUNDS-lost study

Liu, G., Zhang, B., Hu, Y., Rood, J., Liang, L., Qi, L., Bray, G. A., DeJonge, L., Coull, B., Grandjean, P., Furtado, J. D. & Sun, Q., 13. Jan 2020, In : Environmental Health: A Global Access Science Source. 19, 1, p. 5

Research output: Contribution to journalJournal articleResearchpeer-review

Lipoproteins
perfluorooctanoic acid
Lipids
HDL Lipoproteins
Least-Squares Analysis

Higher circulating plasma polychlorinated biphenyls (PCBs) in fit and lean children: The European youth heart study

Domazet, S. L., Grøntved, A., Jensen, T. K., Wedderkopp, N. & Andersen, L. B., 18. Jan 2020, In : Environment International. 105481.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
PCB
plasma
fat
fitness
physical activity

What is useful research? The good, the bad, and the stable (Editorial)

Ozonoff, D. M. & Grandjean, P., 7. Jan 2020, In : Environmental Health: A Global Access Science Source. 19, 1, p. 2

Research output: Contribution to journalJournal articleResearch

Environmental Health
Research
Lenses
Publications
Public Health
2019
7 Downloads (Pure)

A Birth Cohort Study on the Genetic Modification of the Association of Prenatal Methylmercury With Child Cognitive Development

Julvez, J., Smith, G. D., Ring, S. M. & Grandjean, P., Oct 2019, In : American Journal of Epidemiology. 188, 10, p. 1784-1793

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cohort Studies
Mercury
Progesterone Receptors
Single Nucleotide Polymorphism
Alleles
Polycystic Ovary Syndrome
Mothers
Penis
Denmark
Research

A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24

Mirza, M. R., Bergmann, T. K., Mau-Sørensen, M., Christensen, R. D., Åvall-Lundqvist, E., Birrer, M. J., Jørgensen, M., Roed, H., Malander, S., Nielsen, F., Lassen, U., Brøsen, K., Bjørge, L. & Mäenpää, J., Oct 2019, In : Cancer Chemotherapy and Pharmacology. 84, 4, p. 791-798

Research output: Contribution to journalJournal articleResearchpeer-review

Platinum
Angiogenesis Inhibitors
Germ-Line Mutation
Ovarian Neoplasms
Disease-Free Survival

A randomised, double-blind, placebo-controlled trial of metformin on myocardial efficiency in insulin-resistant chronic heart failure patients without diabetes

Larsen, A. H., Jessen, N., Nørrelund, H., Tolbod, L. P., Harms, H. J., Feddersen, S., Nielsen, F., Brøsen, K., Hansson, N. H., Frøkiaer, J., Poulsen, S. H., Sörensen, J. & Wiggers, H., 21. Dec 2019, In : European Journal of Heart Failure.

Research output: Contribution to journalJournal articleResearchpeer-review

Placebos
Insulin
Oxygen Consumption
Confidence Intervals
Exercise
29 Downloads (Pure)
Open Access
File
Mothers
perfluorooctanoic acid
Endocrine Disruptors
Denmark
Parity
69 Downloads (Pure)

A strategy to validate a selection of human effect biomarkers using adverse outcome pathways: Proof of concept for phthalates and reproductive effects

Baken, K. A., Lambrechts, N., Remy, S., Mustieles, V., Rodríguez-Carrillo, A., Neophytou, C. M., Olea, N. & Schoeters, G., 2019, In : Environmental Research. 175, p. 235-256

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
phthalate
Biomarkers
biomarker
Peroxisome Proliferator-Activated Receptors
Health

Bone mineral density is preserved in men with idiopathic infertility

Antonio, L., Priskorn, L., Nordkap, L., Bang, A. K., Jensen, T. K., Skakkebæk, N. E., Petersen, J. H., Vanderschueren, D. & Jørgensen, N., 2019, In : Journal of Andrology.

Research output: Contribution to journalJournal articleResearchpeer-review

Bone Density
Infertility
Femur Neck
Photon Absorptiometry
Semen

Child behaviour and subsequent changes in body weight, composition and shape

Christensen, K. G., Nielsen, S. G., Olsen, N. J., Dålgard, C., Heitmann, B. L. & Larsen, S. C., 2019, In : PLOS ONE. 14, 12, 10 p., e0226003.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
body weight changes
Child Behavior
questionnaires
Association reactions
Chemical analysis
5 Downloads (Pure)

Developmental fluoride neurotoxicity: an updated review

Grandjean, P., 19. Dec 2019, In : Environmental Health: A Global Access Science Source. 18, 1, 17 p., 110.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Preventive Dentistry
Topical Fluorides
Fluoridation
Benchmarking
Mexico

Development priority

Grandjean, P., Prins, G. S. & Weihe, P., Aug 2019, In : Basic & Clinical Pharmacology & Toxicology. 125, S3, p. 3-4

Research output: Contribution to journalEditorialResearchpeer-review

Early life exposures to perfluoroalkyl substances in relation to adipokine hormone levels at birth and during childhood

Shelly, C., Grandjean, P., Oulhote, Y., Plomgaard, P., Frikke-Schmidt, R., Nielsen, F., Zmirou-Navier, D., Weihe, P. & Valvi, D., 1. Nov 2019, In : The Journal of clinical endocrinology and metabolism. 104, 11, p. 5338-5348

Research output: Contribution to journalJournal articleResearchpeer-review

Adipokines
Resistin
Hormones
Adiponectin
Leptin

Endocrine disrupters, semen quality and anogenital distance

Jensen, T. K., Aug 2019, In : Current Opinion in Endocrine and Metabolic Research. 7, p. 34-42

Research output: Contribution to journalReviewResearchpeer-review

Maternal Exposure
Chlorinated Hydrocarbons
Endocrine Disruptors
Reproductive Health
Meta-Analysis

Endocrine-distributing chemicals and reproductive function.

Araki, A. & Jensen, T. K., 2019, Health Impacts of Developmental Exposure to Environmental Chemicals. Kishi, R. & grandjean, P. (eds.). Springer, p. 101-128 (Current Topics in Environmental Health and Preventive Medicine).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

77 Downloads (Pure)

Environmental chemical exposures among Greenlandic children in relation to diet and residence

Timmermann, C. A. G., Pedersen, H. S., Budtz-Jørgensen, E., Bjerregaard, P., Oulhote, Y., Weihe, P., Nielsen, F. & Grandjean, P., Dec 2019, In : International Journal of Circumpolar Health. 78, 1, 11 p., 1642090.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Environmental Exposure
Diet
Proxy
Mercury
Linear Models

Fish Consumption During Pregnancy

Grandjean, P., Lederman, S. A. & Silbergeld, E. K., 1. Mar 2019, In : JAMA Pediatrics. 173, 3, p. 292

Research output: Contribution to journalComment/debateResearch

38 Downloads (Pure)

Gender differences in cognitive performance and health status in the Faroese Septuagenarians cohort

Petersen, M. S., Debes, F., Grandjean, P. & Weihe, P., Feb 2019, In : European Journal of Public Health. 29, 1, p. 79–81

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Joint Diseases
Myalgia
Cross-Sectional Studies
Health
Surveys and Questionnaires

Hair cortisol in newly diagnosed bipolar disorder and unaffected first-degree relatives

Coello, K., Munkholm, K., Nielsen, F., Vinberg, M. & Kessing, L. V., Jan 2019, In : Psychoneuroendocrinology. 99, p. 183-190

Research output: Contribution to journalJournal articleResearchpeer-review

Hair
Wounds and Injuries
15 Downloads (Pure)

Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors

Shaffer, R. M., Sellers, S. P., Baker, M. G., de Buen Kalman, R., Frostad, J., Suter, M. K., Anenberg, S. C., Balbus, J., Basu, N., Bellinger, D. C., Birnbaum, L., Brauer, M., Cohen, A., Ebi, K. L., Fuller, R., Grandjean, P., Hess, J. J., Kogevinas, M., Kumar, P., Landrigan, P. J. & 7 others, Lanphear, B., London, S. J., Rooney, A. A., Stanaway, J. D., Trasande, L., Walker, K. & Hu, H., Oct 2019, In : Environmental Health Perspectives. 127, 10, p. 105001-1-105001-16

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Environmental Health
Air Pollution
Health
Endocrine Disruptors
Premature Mortality

Joint and independent neurotoxic effects of early life exposures to a chemical mixture: A multi-pollutant approach combining ensemble learning and g-computation

Oulhote, Y., Coull, B., Bind, M-A., Debes, F., Nielsen, F., Tamayo, I., Weihe, P. & Grandjean, P., Oct 2019, In : Environmental Epidemiology. 3, 5, 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Joints
Confidence Intervals
perfluorooctanoic acid
Mothers
Mercury

Mothers and children are related, even in exposure to chemicals present in common consumer products

Koppen, G., Govarts, E., Vanermen, G., Voorspoels, S., Govindan, M., Dewolf, M. C., Den Hond, E., Biot, P., Casteleyn, L., Kolossa-Gehring, M., Schwedler, G., Angerer, J., Koch, H. M., Schindler, B. K., Castaño, A., López, M. E., Sepai, O., Exley, K., Bloemen, L., Knudsen, L. E. & 4 others, Joas, R., Joas, A., Schoeters, G. & Covaci, A., Aug 2019, In : Environmental Research. 175, p. 297-307

Research output: Contribution to journalJournal articleResearchpeer-review

Consumer products
phthalate
Triclosan
Mothers
Dibutyl Phthalate

Perfluorinated substances, risk factors for multiple sclerosis and cellular immune activation

Ammitzbøll, C., Börnsen, L., Petersen, E. R., Oturai, A. B., Søndergaard, H. B., Grandjean, P. & Sellebjerg, F., 15. May 2019, In : Journal of Neuroimmunology. 330, p. 90-95

Research output: Contribution to journalJournal articleResearchpeer-review

Smoking
perfluorooctane sulfonic acid

Perfluoroalkyl substances and changes in bone mineral density: A prospective analysis in the POUNDS-LOST study

Hu, Y., Liu, G., Rood, J., Liang, L., Bray, G. A., de Jonge, L., Coull, B., Furtado, J. D., Qi, L., Grandjean, P. & Sun, Q., 2019, In : Environmental Research. 179, 7 p., 108775.

Research output: Contribution to journalJournal articleResearchpeer-review

Bone Density
Minerals
bone
Bone
Hip

PFASs and decreased Vaccine Response in Guinea-Bissau Children

Timmermann, A., Jun 2019.

Research output: Contribution to conference without publisher/journalPosterResearch

7 Downloads (Pure)

Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances

Eryasa, B., Grandjean, P., Nielsen, F., Valvi, D., Zmirou-Navier, D., Sunderland, E., Weihe, P. & Oulhote, Y., Sep 2019, In : Environment International. 130, 9 p., 104874.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
diabetes
chemical property
partitioning
blood
serum
Adiposity
Adipose Tissue
Cohort Studies
Mothers
Linear Models

Prenatal bisphenol A exposure is associated with language development but not with ADHD-related behavior in toddlers from the Odense Child Cohort

Jensen, T. K., Mustieles, V., Bleses, D., Frederiksen, H., Trecca, F., Schoeters, G., Andersen, H. R., Grandjean, P., Kyhl, H. B., Juul, A., Bilenberg, N. & Andersson, A. M., 1. Mar 2019, In : Environmental Research. 170, p. 398-405

Research output: Contribution to journalJournal articleResearchpeer-review

Mothers
urine
Urine
breastfeeding
fasting
65 Downloads (Pure)

Prevalence of prediabetes and type 2 diabetes in two non-random populations aged 44–77 years in the Faroe Islands

Veyhe, A. S., Andreassen, J., Halling, J., Grandjean, P., Skaalum Petersen, M. & Weihe, P., Jun 2019, In : Journal of Clinical and Translational Endocrinology. 16, 8 p., 100187.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Prediabetic State
Denmark
Type 2 Diabetes Mellitus
Population
Fasting
14 Downloads (Pure)

Response to Juberg et al

Mie, A., Rudén, C. & Grandjean, P., 2019, In : Environmental Health. 18, 3 p., 29.

Research output: Contribution to journalLetterResearch

Open Access
File
64 Downloads (Pure)

Tap water contributions to plasma concentrations of poly- and perfluoroalkyl substances (PFAS) in a nationwide prospective cohort of U.S. women

Hu, X. C., Tokranov, A. K., Liddie, J., Zhang, X., Grandjean, P., Hart, J. E., Laden, F., Sun, Q., Yeung, L. W. Y. & Sunderland, E. M., Jun 2019, In : Environmental Health Perspectives. 127, 6, 11 p., 067006.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
perfluorooctanoic acid
Nurses
United States Environmental Protection Agency
Fluorine
Water Supply
Registries
Twin Studies
Denmark
Polycystic Ovary Syndrome
Third Pregnancy Trimester
Mothers
Cortisone
Fasting
40 Downloads (Pure)

Time scales of developmental toxicity impacting on research and needs for intervention

Grandjean, P., Abdennebi-Najar, L., Barouki, R., Cranor, C. F., Etzel, R. A., Gee, D., Heindel, J. J., Hougaard, K. S., Hunt, P., Nawrot, T. S., Prins, G. S., Ritz, B., Soffritti, M., Sunyer, J. & Weihe, P., Aug 2019, In : Basic & Clinical Pharmacology & Toxicology. 125, Suppl. 3, p. 70-80

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Toxicity
Research
Health
Computational chemistry
Epidemiology
2018

Accelerated functional losses in ageing congenital Minamata disease patients

Yorifuji, T., Takaoka, S. & Grandjean, P., 10. Aug 2018, In : Neurotoxicology and Teratology. 69, p. 49-53

Research output: Contribution to journalJournal articleResearchpeer-review

Nervous System Mercury Poisoning
Aging of materials
Cognition
Cerebral Palsy
Poisoning

Anogenital distance as a phenotypic signature through infancy

Priskorn, L., Petersen, J. H., Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, K. M., Andersson, A-M., Skakkebaek, N. E. & Jensen, T. K., Mar 2018, In : Pediatric Research. 83, 3, p. 573–579

Research output: Contribution to journalJournal articleResearchpeer-review

Clitoris
Scrotum
Penis
Equidae
Pediatrics
124 Downloads (Pure)

A novel inverse association between cord 25-hydroxyvitamin D and leg length in boys up to three years: An Odense Child Cohort study

Christensen, M. E., Beck-Nielsen, S. S., Dalgård, C., Larsen, S. D., Lykkedegn, S., Kyhl, H. B., Husby, S. & Christesen, H. T., 1. Jun 2018, In : PLOS ONE. 13, 6, 17 p., e0198724.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
cohort studies
Leg
legs
Cohort Studies
rickets
82 Downloads (Pure)

Application of benchmark analysis for mixed contaminant exposures: Mutual adjustment of perfluoroalkylate substances associated with immunotoxicity

Budtz-Jørgensen, E. & Grandjean, P., 2018, In : PLOS ONE. 13, 10, 14 p., e0205388.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
immunotoxicity
Benchmarking
Impurities
Antibodies
dosage
122 Downloads (Pure)
Open Access
File
Maternal Exposure
Pyrethrins
2,4-Dichlorophenoxyacetic Acid
Organophosphates
Herbicides
91 Downloads (Pure)

A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission

Audouze, K., Taboureau, O. & Grandjean, P., Sep 2018, In : Toxicology and Applied Pharmacology. 354, p. 56-63

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
pyriproxyfen
Systems Biology
Viruses
Microcephaly
Toxicity

Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years

Priskorn, L., Nordkap, L., Bang, A. K., Krause, M., Holmboe, S. A., Egeberg Palme, D. L., Winge, S. B., Mørup, N., Carlsen, E., Joensen, U. N., Blomberg Jensen, M., Main, K. M., Juul, A., Skakkebaek, N. E., Jensen, T. K. & Jørgensen, N., 1. Jun 2018, In : Human Reproduction. 33, 6, p. 998-1008

Research output: Contribution to journalJournal articleResearchpeer-review

Cross-Sectional Studies
Smoking
Mothers
Maternal Exposure
Semen
75 Downloads (Pure)

Blood pressure in 3-year-old girls associates inversely with umbilical cord serum 25-hydroxyvitamin D: an Odense Child Cohort study

Larsen, S. D., Dalgård, C., Christensen, M. E., Lykkedegn, S., Andersen, L. B., Andersen, M., Glintborg, D. & Christesen, H. T., 1. Oct 2018, In : Endocrine Connections. 7, 12, p. 1236–1244

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Umbilical Cord
Cohort Studies
Serum
25-Hydroxyvitamin D 2
Mothers
114 Downloads (Pure)

Can profiles of poly- and Perfluoroalkyl substances (PFASs) in human serum provide information on major exposure sources?

Hu, X. C., Dassuncao, C., Zhang, X., Grandjean, P., Weihe, P., Webster, G. M., Nielsen, F. & Sunderland, E. M., 1. Feb 2018, In : Environmental Health: A Global Access Science Source. 17, 15 p., 11.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Serum
Seafood
perfluorooctanoic acid
Population
Health