Research Output 1989 2020

2018

Decreased mortality in patients with acute cholangitis despite an increase in malignant etiologies – A 25-year epidemiological study

Tan, M., Schaffalitzky de Muckadell, O. B. & Laursen, S. B., Jun 2018, In : Gastrointestinal Endoscopy. 87, 6 Suppl., p. AB224–AB225 Sa1348.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

69 Downloads (Pure)

Design of the Prospective Real-world Outcomes Study of hepatic encephalopathy Patients' Experience on Rifaximin-α (PROSPER): an observational study among 550 patients

Krag, A., Schuchmann, M., Sodatonou, H., Pilot, J., Whitehouse, J., Strasser, S. I. & Hudson, M., 2018, In : Hepatology, Medicine and Policy. 3, 8 p., 4.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hepatic Encephalopathy
Outcome Assessment (Health Care)
Caregivers
Quality of Life
Ammonia
130 Downloads (Pure)

Development and predictive validity of the cirrhosisassociated ascites symptom scale: A cohort study of 103 patients

Riedel, A. N., Kimer, N., Jensen, A. S. H., Dahl, E. K., Israelsen, M., Aamann, L. & Gluud, L. L., 21. Apr 2018, In : World Journal of Gastroenterology. 24, 15, p. 1650-1657

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cohort Studies
Quality of Life
Liver Diseases

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

Krag, A. & European Association for the Study of the Liver, Aug 2018, In : Journal of Hepatology. 69, 2, p. 406-460

Research output: Contribution to journalJournal articleCommunication

152 Downloads (Pure)
Open Access
File
Psoriatic Arthritis
Randomized Controlled Trials
Placebos
Safety
Psoriasis
85 Downloads (Pure)

Exposure to previous cART is associated with significant liver fibrosis and cirrhosis in human immunodeficiency virus-infected patients

Anadol, E., Lust, K., Boesecke, C., Schwarze-Zander, C., Mohr, R., Wasmuth, J-C., Rockstroh, J. K. & Trebicka, J., 1. Jan 2018, In : PLOS ONE. 13, 1, 12 p., e0191118.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Didanosine
liver cirrhosis
Human immunodeficiency virus
Viruses
Liver Cirrhosis

External validation of the international bleeding risk score in both upper and lower GI bleeding: An international multicentre study

Laursen, S. B., Oakland, K., Laine, L., Bieber, V., Marmo, R., Redondo Cerezo, E., Dalton, H. R., Ngu, JH., Schultz, M., Gralnek, I., Jairath, V., Murray, AI. & Stanley, AJ., 2018, In : United European Gastroenterology Journal. 6, Suppl. 8, p. A126-A127 1 p., OP316.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
133 Downloads (Pure)

Fat-free muscle mass in magnetic resonance imaging predicts acute-on-chronic liver failure and survival in decompensated cirrhosis

Praktiknjo, M., Book, M., Luetkens, J., Pohlmann, A., Meyer, C., Thomas, D., Jansen, C., Feist, A., Chang, J., Grimm, J., Lehmann, J., Strassburg, C. P., Abraldes, J. G., Kukuk, G. & Trebicka, J., Mar 2018, In : Hepatology. 67, 3, p. 1014-1026

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Transjugular Intrahepatic Portasystemic Shunt
Fats
Sarcopenia
Muscles
Psoas Muscles

Fecal Calprotectin during Pregnancy in Women with Moderate-Severe Inflammatory Bowel Disease

Kammerlander, H., Nielsen, J., Kjeldsen, J., Knudsen, T., Gradel, K. O., Friedman, S. & Nørgård, B. M., 19. Mar 2018, In : Inflammatory Bowel Diseases. 24, 4, p. 839-848

Research output: Contribution to journalJournal articleResearchpeer-review

Inflammatory Bowel Diseases
Confidence Intervals
Pregnant Women
Albumins
Third Pregnancy Trimester

Fibroblast growth factor 21 is an early predictor of acute-on-chronic liver failure in critically ill patients with cirrhosis

Ruiz-Margáin, A., Pohlmann, A., Ryan, P., Schierwagen, R., Chi-Cervera, L. A., Jansen, C., Mendez-Guerrero, O., Flores-García, N. C., Lehmann, J., Torre, A., Macías-Rodríguez, R. U. & Trebicka, J., 1. May 2018, In : Liver Transplantation. 24, 5, p. 595-605

Research output: Contribution to journalJournal articleResearchpeer-review

Critical Illness
Interleukin-8
Liver Transplantation
Acute-On-Chronic Liver Failure
fibroblast growth factor 21

Genetically determined high activity of IL-12 and IL-18 in ulcerative colitis and TLR5 in Crohns disease were associated with non-response to anti-TNF therapy

Bank, S., Andersen, P. S., Burisch, J., Pedersen, N., Roug, S., Galsgaard, J., Turino, S. Y., Brodersen, J. B., Rashid, S., Rasmussen, B. K., Avlund, S., Olesen, T. B., Hoffmann, H. J., Nexø, B. A., Sode, J., Vogel, U. & Andersen, V., Jan 2018, In : The Pharmacogenomics Journal. 18, 1, p. 87–97

Research output: Contribution to journalJournal articleResearchpeer-review

Interleukin-18
Ulcerative Colitis
Crohn Disease
Single Nucleotide Polymorphism
Inflammatory Bowel Diseases
61 Downloads (Pure)

Gut-Liver Axis Links Portal Hypertension to Acute-on-Chronic Liver Failure

Trebicka, J., Reiberger, T. & Laleman, W., Aug 2018, In : Visceral Medicine. 34, 4, p. 270-275

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Portal Hypertension
Liver
Liver Diseases
Portal Pressure
Acute-On-Chronic Liver Failure

HOME PARENTERAL NUTRITION INCREASES FAT FREE MASS IN PATIENTS WITH INCURABLE GASTROINTESTINAL CANCER. RESULTS OF A RCT.

Obling, S. R., 2018.

Research output: Contribution to conference without publisher/journalPosterCommunication

Home parenteral nutrition in patients with incurable cancer

Obling, S. R., 2018, Odense: Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet.

Research output: Book/anthology/thesis/reportPh.D. thesisResearch

10 Downloads (Pure)

Home parenteral support in patients with incurable cancer. Patient characteristics of importance for catheter related complications and overall survival

Obling, S. R., Wilson, B. V. & Kjeldsen, J., 1. Dec 2018, In : Clinical Nutrition ESPEN. 28, p. 88-95

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Catheters
Neoplasms
Gastrointestinal Neoplasms
Regression Analysis
Intestinal Neoplasms

IgG4-related sclerosing cholangitis involving the intrahepatic bile ducts diagnosed with liver biopsy

Thinesen, M. T., Schaffalitzky de Muckadell, O. B. & Detlefsen, S., 2018.

Research output: Contribution to conference without publisher/journalPosterResearch

90 Downloads (Pure)

IgG4-Related Sclerosing Cholangitis Involving the Intrahepatic Bile Ducts Diagnosed with Liver Biopsy

Thinesen, M. T., Schaffalitzky de Muckadell, O. B. & Detlefsen, S., 2018, In : Case Reports in Pathology. 2018, 7 p., 2309293.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Sclerosing Cholangitis
Liver
Cholangiography
Groin
Deglutition Disorders
127 Downloads (Pure)

Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, Bojesen, A. B., Sorensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexøe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., Feb 2018, In : B M J Open. 8, 2, 17 p., e018166.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Precision Medicine
Cohort Studies
Prospective Studies
Tumor Necrosis Factor-alpha
Hidradenitis Suppurativa
13 Downloads (Pure)

Increased myocardial contractility identifies patients with decompensated cirrhosis requiring liver transplantation

Jansen, C., Cox, A., Schueler, R., Schneider, M., Lehmann, J., Praktiknjo, M., Pohlmann, A., Chang, J., Manekeller, S., Nickenig, G., Berlakovich, G., Strassburg, C. P., Hammerstingl, C., Staufer, K. & Trebicka, J., 1. Jan 2018, In : Liver Transplantation. 24, 1, p. 15-25

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Liver Transplantation
Heart Ventricles
Echocardiography
Retrospective Studies
82 Downloads (Pure)

Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality

Jansen, C., Möller, P., Meyer, C., Kolbe, C. C., Bogs, C., Pohlmann, A., Schierwagen, R., Praktiknjo, M., Abdullah, Z., Lehmann, J., Thomas, D., Strassburg, C. P., Latz, E., Mueller, S., Rössle, M. & Trebicka, J., 1. Apr 2018, In : Hepatology (Baltimore, Md.). 67, 4, p. 1472-1484

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Transjugular Intrahepatic Portasystemic Shunt
Liver
Portal Hypertension
Interleukin-18
Hepatic Veins

International multicentre study of Mallory Weiss tear related GI bleeding: demographics, endoscopic therapy and outcome

Lynch, L., Laursen, S. B., Laine, L., Dalton, H. R., Michell, N., Ngu, JH., Schultz, M. & Stanley, AJ., 2018, In : Gut. 67, Suppl. 1, p. A147-A148 1 p., PTH-119.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Letter: vedolizumab drug levels in cord and maternal blood in women with inflammatory bowel disease

Julsgaard, M., Kjeldsen, J., Brock, B. & Baumgart, D. C., Aug 2018, In : Alimentary Pharmacology and Therapeutics. 48, 3, p. 386-388

Research output: Contribution to journalComment/debateResearch

Managing excessive alcohol consumption at a population level: The earlier the better

Louvet, A. & Krag, A., 1. Mar 2018, In : Journal of Hepatology. 68, 3, p. 389-390

Research output: Contribution to journalEditorialResearchpeer-review

61 Downloads (Pure)

Non-cirrhotic portal hypertension: A possibly benign but complicated disease

Trebicka, J., 1. Aug 2018, In : Digestive and Liver Disease. 50, 8, p. 845-846

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File

Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis

Nguyen-Khac, E., Thiele, M., Voican, C., Nahon, P., Moreno, C., Boursier, J., Mueller, S., de Ledinghen, V., Stärkel, P., Gyune Kim, S., Fernandez, M., Madsen, B., Naveau, S., Krag, A., Perlemuter, G., Ziol, M., Chatelain, D. & Diouf, M., 1. Sep 2018, In : The Lancet Gastroenterology and Hepatology. 3, 9, p. 614-625

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Cirrhosis
Meta-Analysis
Liver Diseases
Alcohols
Alcoholic Hepatitis

Omalizumab prevents anaphylaxis and improves symptoms in systemic mastocytosis: Efficacy and safety observations

Broesby-Olsen, S., Vestergaard, H., Mortz, C. G., Jensen, B., Havelund, T., Hermann, A. P., Siebenhaar, F., Møller, M. B., Kristensen, T. K., Bindslev-Jensen, C. & Mastocytosis Centre Odense University Hospital (MastOUH), Jan 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 1, p. 230–238

Research output: Contribution to journalJournal articleResearchpeer-review

Systemic Mastocytosis
Safety
Tryptases
Mast Cells
Alleles

Outcomes with Bloody vs. Coffee-Grounds Hematemesis

Laine, L., Laursen, S. B. & Stanley, A. J., Nov 2018, In : American Journal of Gastroenterology. 113, 11, p. 1727–1728

Research output: Contribution to journalComment/debateResearchpeer-review

Pediatric Inflammatory Bowel Diseases: Should We Be Looking for Kidney Abnormalities?

Lauritzen, D., Andreassen, B. U., Heegaard, N. H. H., Klinge, L. G., Walsted, A-M., Neland, M., Nielsen, R. G. & Wittenhagen, P., 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2599–2605

Research output: Contribution to journalJournal articleResearchpeer-review

Inflammatory Bowel Diseases
Pediatrics
Kidney
Kidney Diseases
Small Intestine

Peroral kolangioskopi

Risanger, L. I., Pedersen, F. M. & Laursen, S. B., 2018, In : Ugeskrift for Laeger. 179, 7, p. 603-606 V02170158.

Research output: Contribution to journalJournal articleResearchpeer-review

Quantification of liver fibrosis at T1 and T2 mapping with extracellular volume fraction MRI: Preclinical results

Luetkens, J. A., Klein, S., Träber, F., Schmeel, F. C., Sprinkart, A. M., Kuetting, D. L. R., Block, W., Uschner, F. E., Schierwagen, R., Hittatiya, K., Kristiansen, G., Gieseke, J., Schild, H. H., Trebicka, J. & Kukuk, G. M., 1. Sep 2018, In : Radiology. 288, 3, p. 748-754

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Cirrhosis
Ligation
Portal Pressure
Hydroxyproline
Smooth Muscle

Quantitative liver MRI including extracellular volume fraction for non-invasive quantification of liver fibrosis: a prospective proof-of-concept study

Luetkens, J. A., Klein, S., Traeber, F., Schmeel, F. C., Sprinkart, A. M., Kuetting, D. L. R., Block, W., Hittatiya, K., Uschner, F. E., Schierwagen, R., Gieseke, J., Schild, H. H., Trebicka, J. & Kukuk, G. M., Mar 2018, In : Gut. 67, 3, p. 593-594

Research output: Contribution to journalComment/debateResearchpeer-review

Rebleeding in Peptic Ulcer Bleeding - a Nationwide Cohort Study of 19,537 Patients.

Laursen, S. B., Laine, L., Stanley, A. J. & Schaffalitzky de Muckadell, O. B., 2018, In : Gastroenterology. 154, Suppl. 1, p. S-701 1 p., Mo1188.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Reduced platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis

Vinholt, P. J., Hvas, A-M., Nielsen, C., Söderström, A. C., Sprogøe, U., Fialla, A. D. & Nybo, M., 4. Jul 2018, In : Platelets. 29, 5, p. 520-527

Research output: Contribution to journalJournal articleResearchpeer-review

Alcoholic Liver Cirrhosis
Platelet Aggregation
Platelet Count
Liver Cirrhosis
Platelet Glycoprotein GPIIb-IIIa Complex
185 Downloads (Pure)

Return-to-health effect of modern combined antiretroviral therapy potentially predisposes HIV patients to hepatic steatosis

Mohr, R., Boesecke, C., Dold, L., Schierwagen, R., Schwarze-Zander, C., Wasmuth, J-C., Weisensee, I., Rockstroh, J. K. & Trebicka, J., 1. Apr 2018, In : Medicine. 97, 17, 7 p., e0462.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
HIV
Liver
Health
Glycosylated Hemoglobin A
Virus Diseases
101 Downloads (Pure)

Rifaximin has minor effects on bacterial composition, inflammation and bacterial translocation in cirrhosis: A randomized trial

Kimer, N., Pedersen, J. S., Tavenier, J., Christensen, J. E., Busk, T. M., Hobolth, L., Krag, A., Al-Soud, W. A., Mortensen, M. S., Sørensen, S. J., Møller, S., Bendtsen, F. & And members of the CoRif study group, Jan 2018, In : Journal of Gastroenterology and Hepatology. 33, 1, p. 307–314

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Bacterial Translocation
rRNA Genes
Feces
Placebos
Bacterial DNA

Ruling out esophageal varices in NAFLD cirrhosis: Can we do without endoscopy?

de Franchis, R. & Krag, A., 1. Oct 2018, In : Journal of Hepatology. 69, 4, p. 769-771

Research output: Contribution to journalEditorialResearchpeer-review

Sådan påvirker decembers flæsk, sovs og snaps din fordøjelse

Thiele, M., 9. Dec 2018, In : Videnskab.dk.

Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

92 Downloads (Pure)

Serum type XVI collagen is associated with colorectal cancer and ulcerative colitis indicating a pathological role in gastrointestinal disorders

Jensen, C., Nielsen, S. H., Mortensen, J. H., Kjeldsen, J., Klinge, L. G., Krag, A., Harling, H., Jørgensen, L. N., Karsdal, M. A. & Willumsen, N., 20. Aug 2018, In : Cancer Medicine. 7, 9, p. 4619-4626

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Ulcerative Colitis
Colorectal Neoplasms
Serum
Intestines
Odds Ratio
91 Downloads (Pure)

Severe abnormal Heart Rate Turbulence Onset is associated with deterioration of liver cirrhosis

Jansen, C., Al-Kassou, B., Lehmann, J., Pohlmann, A., Chang, J., Praktiknjo, M., Nickenig, G., Strassburg, C. P., Schrickel, J. W., Andrié, R., Linhart, M. & Trebicka, J., 1. Apr 2018, In : PLOS ONE. 13, 4, 10 p., e0195631.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
liver cirrhosis
Liver Cirrhosis
Liver
Deterioration
heart rate

Severity and outcomes of upper gastrointestinal bleeding with bloody vs. coffee-grounds hematemesis

Laine, L., Laursen, S. B., Zakko, L., Dalton, H. R., Ngu, J. H., Schultz, M. & Stanley, A. J., 1. Mar 2018, In : American Journal of Gastroenterology. 113, 3, p. 358-366

Research output: Contribution to journalJournal articleResearchpeer-review

Hematemesis
Coffee
Melena
Hemostatics

Should we be using the shock index to assess patients presenting with upper GI bleeding

Blackwell, C., Laursen, S. B., Laine, L., Dalton, H. R., Ngu, JH., Schultz, M., Stanley, AJ. & Norton, R., 2018, In : United European Gastroenterology Journal. 6, 8. Suppl., p. A12-A13 1 p., OP028.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Should we be using the shock index to assess patients presenting with upper GI bleeding

Blackwell, C., Laursen, S. B., Laine, L., Dalton, H. R., Ngu, JH., Schultz, M., Norton, R. & Stanley, AJ., 2018, In : Gut. 67, Suppl. 1, p. A3 1 p., OWE-006.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

93 Downloads (Pure)

Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough

Laleman, W., Claria, J., Van der Merwe, S., Moreau, R. & Trebicka, J., 1. Jan 2018, In : Canadian Journal of Gastroenterology and Hepatology. 2018, 10 p., 1027152.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Albumins
Prebiotics
Plasma Exchange
Probiotics
Acute-On-Chronic Liver Failure
98 Downloads (Pure)

The multikinase inhibitor regorafenib decreases angiogenesis and improves portal hypertension

Uschner, F. E., Schueller, F., Nikolova, I., Klein, S., Schierwagen, R., Magdaleno, F., Gröschl, S., Loosen, S., Ritz, T., Roderburg, C., Vucur, M., Kristiansen, G., Lammers, T., Luedde, T. & Trebicka, J., 1. Nov 2018, In : Oncotarget. 9, 90, p. 36220-36237

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Portal Hypertension
Hepatocellular Carcinoma
Portal Vein
Ligation
Liver
125 Downloads (Pure)

The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats

Schwabl, P., Brusilovskaya, K., Supper, P., Bauer, D., Königshofer, P., Riedl, F., Hayden, H., Fuchs, C. D., Stift, J., Oberhuber, G., Aschauer, S., Bonderman, DI., Gnad, T., Pfeifer, A., Uschner, F. E., Trebicka, J., Rohr-Udilova, N., Podesser, B. K., Peck-Radosavljevic, M., Trauner, M. & 1 others, Reiberger, T., 19. Jun 2018, In : Scientific Reports. 8, 13 p., 9372.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Portal Pressure
Portal Hypertension
Ligation
Liver Cirrhosis
Pulmonary Hypertension

Timing af endoskopisk retrograd kolangiopankreatografi ved akut kolangitis

Translated title of the contribution: Timing of endoscopic retrograde cholangiopancreatography in patients with acute cholangitis:Tan, M., Schaffalitzky de Muckadell, O. B. & Laursen, S. B., 2. Apr 2018, In : Ugeskrift for Laeger. 180, 7, p. 595-598 V10170806.

Research output: Contribution to journalJournal articleResearchpeer-review