Research Output 1989 2019

2019

17q12-deletion som mulig årsag til dorsal pancreasagenesi og polycystisk nyresygdom

Translated title of the contribution: 17q12 deletion as a possible cause of agenesis of the dorsal pancreas and polycystic kidney diseaseAndersen, B. B. & Schaffalitzky, O. B., 18. Nov 2019, In : Ugeskrift for Laeger. 181, V08190452.

Research output: Contribution to journalJournal articleResearchpeer-review

Asperger Syndrome
Chromosome Deletion
Pancreas

Adalimumab in the treatment of chronic pouchitis. A randomized double-blind, placebo-controlled trial

Kjær, M. D., Qvist, N., Nordgaard-Lassen, I., Christensen, L. A. & Kjeldsen, J., 10. Feb 2019, In : Scandinavian Journal of Gastroenterology. 54, 2, p. 188-193

Research output: Contribution to journalJournal articleResearchpeer-review

Pouchitis
Placebos
Adalimumab
Colonic Pouches
77 Downloads (Pure)

ADAPT: An algorithm incorporating PRO-C3 accurately identifies patients with NAFLD and advanced fibrosis

Daniels, S. J., Leeming, D. J., Eslam, M., Hashem, A. M., Nielsen, M. J., Krag, A., Karsdal, M. A., Grove, J. I., Guha, I. N., Kawaguchi, T., Torimura, T., McLeod, D., Akiba, J., Kaye, P., de Boer, B., Aithal, G. P., Adams, L. A. & George, J., Mar 2019, In : Hepatology (Baltimore, Md.). 69, 3, p. 1075-1086

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Confidence Intervals
Collagen Type III
Liver
Platelet Count
ROC Curve

A model to predict the risk of aspirin/NSAID-related upper gastrointestinal bleeding for the individual patient

Petersen, J., Møller Hansen, J., de Muckadell, O. B. S., Dall, M. & Hallas, J., 25. Nov 2019, In : Basic & Clinical Pharmacology & Toxicology.

Research output: Contribution to journalJournal articleResearchpeer-review

Aspirin
Anti-Inflammatory Agents
Pharmaceutical Preparations
Ulcer
Incidence

Anti-TNF Therapy in Pregnant Women With Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes

Julsgaard, M., Hvas, C. L., Gearry, R. B., Gibson, P. R., Fallingborg, J., Sparrow, M. P., Bibby, B. M., Connell, W. R., Brown, S. J., Kamm, M. A., Lawrance, I. C., Vestergaard, T., Svenningsen, L., Baekdal, M., Kammerlander, H., Walsh, A., Boysen, T., Bampton, P., Radford-Smith, G., Kjeldsen, J. & 10 others, Andrews, J. M., Subramaniam, K., Moore, G. T., Jensen, N. M., Connor, S. J., Wildt, S., Wilson, B., Ellard, K., Christensen, L. A. & Bell, S. J., 29. May 2019, In : Inflammatory Bowel Diseases.

Research output: Contribution to journalJournal articleResearchpeer-review

Therapeutic Uses
Inflammatory Bowel Diseases
Pregnant Women
Tumor Necrosis Factor-alpha
Counseling

A pilot study in PROMETHEUS: MRI Proton density fat fraction is feasible in morbidly obese patients and results equivalent to liver biopsy

Wernberg, C., 1. Jul 2019.

Research output: Contribution to conference without publisher/journalPosterResearch

Association Between Bacteremia and 30-Day Mortality in Patients with Acute Cholangitis

Tan, M., Jensen, T. G., Nielsen, S. L., Schaffalitzky, O. B. & Laursen, S. B., May 2019, In : Gastroenterology. 156, 6 Suppl. 1, p. S-343 Sa1533.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Association Between Bacteremia and 30-Day Mortality in Patients with Acute Cholangitis (Sa1533)

Tan, M., Jensen, T. G., Nielsen, S. L., Schaffalitzky, O. B. & Laursen, S. B., May 2019. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Autoimmun pankreatitis

Translated title of the contribution: Autoimmune pancreatitisPetersen, B. & Schaffalitzky, O. B., 11. Nov 2019, In : Ugeskrift for Laeger. 181, V07190398.

Research output: Contribution to journalJournal articleResearchpeer-review

Pancreatitis
Obstructive Jaundice
Rare Diseases
Diagnostic Errors
Pancreatic Neoplasms
105 Downloads (Pure)

Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis – Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue

Daniels, S. J., Leeming, D. J., Detlefsen, S., Bruun, M. F., Hjuler, S. T., Henriksen, K., Hein, P., Karsdal, M. A., Brockbank, S. & Cruwys, S., 1. Mar 2019, In : Biomedicine & Pharmacotherapy. 111, p. 926-933

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
PPAR gamma
Fatty Liver
pioglitazone
Rodentia
Theoretical Models
63 Downloads (Pure)

Circulating levels of PRO-C3 reflect liver fibrosis and liver function in HIV positive patients receiving modern cART

Dold, L., Nielsen, M. J., Praktiknjo, M., Schwarze-Zander, C., Boesecke, C., Schierwagen, R., Mohr, R., Wasmuth, J-C., Jansen, C., Bischoff, J., Rockstroh, J. K., Karsdal, M. A., Spengler, U., Trebicka, J. & Leeming, D. J., 2019, In : PLOS ONE. 14, 7, 12 p., e0219526.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
liver cirrhosis
liver function
Liver Cirrhosis
Liver
HIV
63 Downloads (Pure)

Circulating microbiome in blood of different circulatory compartments

Schierwagen, R., Alvarez-Silva, C., Madsen, M. S. A., Kolbe, C. C., Meyer, C., Thomas, D., Uschner, F. E., Magdaleno, F., Jansen, C., Pohlmann, A., Praktiknjo, M., Hischebeth, G. T., Molitor, E., Latz, E., Lelouvier, B., Trebicka, J. & Arumugam, M., Mar 2019, In : Gut. 68, 3, p. 578-580

Research output: Contribution to journalLetterResearchpeer-review

Open Access
File
39 Downloads (Pure)

Collagen type IV remodelling gender-specifically predicts mortality in decompensated cirrhosis

Lehmann, J., Praktiknjo, M., Nielsen, M. J., Schierwagen, R., Meyer, C., Thomas, D., Violi, F., Strassburg, C. P., Bendtsen, F., Møller, S., Krag, A., Karsdal, M. A., Leeming, D. J. & Trebicka, J., May 2019, In : Liver International. 39, 5, p. 885-893

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Collagen Type IV
Transjugular Intrahepatic Portasystemic Shunt
Collagen Type III
Hepatic Veins
Portal Vein

Combination of CCL4 with alcoholic and metabolic injuries mimics human liver fibrosis

Galaxy Consortium, 1. Aug 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 317, 2, p. G182-G194

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Cirrhosis
Wounds and Injuries
Ethanol
Alcoholic Fatty Liver
Pharmaceutical Preparations
77 Downloads (Pure)

Combining liver stiffness with hyaluronic acid provides superior prognostic performance in chronic hepatitis C

Hansen, J. F., Christiansen, K. M., Staugaard, B., Moessner, B. K., Lillevang, S., Krag, A. & Christensen, P. B., 1. Feb 2019, In : PLOS ONE. 14, 2, 17 p., e0212036.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
chronic hepatitis C
hyaluronic acid
Chronic Hepatitis C
Hyaluronic Acid
Liver
91 Downloads (Pure)

Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis

Alvarez-Silva, C., Schierwagen, R., Pohlmann, A., Magdaleno, F., Uschner, F. E., Ryan, P., Vehreschild, M. J. G. T., Claria, J., Latz, E., Lelouvier, B., Arumugam, M. & Trebicka, J., Feb 2019, In : Frontiers in Immunology. 10, FEB, 11 p., 69.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Interleukin-6
Bacterial DNA
Microbiota
Interleukin-8
Patient Advocacy

Cost-effectiveness of non-invasive screening for alcohol-related liver fibrosis

Galaxy Consortium, 8. Oct 2019, In : Hepatology (Baltimore, Md.).

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Liver Cirrhosis
Cost-Benefit Analysis
Quality-Adjusted Life Years
Alcohols
Liver

Den kliniske beslutningsproces og den medicinske journal

Svendsen, J. H., Vilstrup, H. A. & Schaffalitzky, O. B., 2019, Medicinsk Kompendium. de Muckadell, O. B. S., Hastrup Svendsen, J. & Vilstrup, H. (eds.). 19. ed. Munksgaard , Vol. 1. p. 21-28

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

Development and Validation of Machine Learning Models to Predict Outcomes in Ugib with Comparison to Clinical Risk Scores

Shung, D., Au, B., Taylor, RA., Laursen, S. B. & Stanley, A. J., 2019.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort: An Epi-IBD study

Epi-IBD group, Jun 2019, In : Journal of Gastroenterology and Hepatology. 34, 6, p. 996-1003

Research output: Contribution to journalJournal articleResearchpeer-review

Inflammatory Bowel Diseases
Population
Ulcerative Colitis
Crohn Disease
Mesalamine

Does severe bleeding in HHT patients respond to intravenous bevacizumab? Review of the literature and case series

Rosenberg, T., Fialla, A. D., Kjeldsen, J. & Kjeldsen, A. D., 1. Aug 2019, In : Rhinology. 57, 4, p. 242-251

Research output: Contribution to journalReviewResearchpeer-review

Epistaxis
Angiogenesis Inhibitors
Gastrointestinal Tract
Bevacizumab
Nose

Editorial: anti-TNF therapy-a double-edged sword? Authors' reply

Korzenik, J., Larsen, M. D., Nielsen, J., Kjeldsen, J. & Nørgård, B. M., 1. Oct 2019, In : Alimentary Pharmacology and Therapeutics. 50, 7, p. 823-824

Research output: Contribution to journalEditorialResearchpeer-review

Open Access

Editorial: population-based testing for Helicobacter pylori in Western countries. Authors' reply

Høgh, M. B., Kronborg, C., Møller Hansen, J., Wildner-Christensen, M. & Schaffalitzky de Muckadell, O. B., May 2019, In : Alimentary Pharmacology and Therapeutics. 49, 10, p. 1361

Research output: Contribution to journalComment/debateCommunication

Effect of Renal Failure on the Outcome of Upper GI-haemmorhage including Risk Scoring.

Murray, I. A., Haddock, R. E., Menzies-Gow, A., Füchtbauer, D. & Laursen, S. B., 2019.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Endoskopisk behandling af ulcusblødning

Laursen, S. B., Karstensen, JG. & Vilmann, P., 2019, Kirurgisk atlas. FADL's Forlag

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

En million danskere har fedtlever. Her er 5 gode råd til at undgå bekymring og store undersøgelser

Gluud, L. L., Fialla, A. D. & Thiele, M., 14. Oct 2019, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide

International Club of Ascites Global Study Group, 1. Apr 2019, In : Gastroenterology. 156, 5, p. 1368-1380.e10

Research output: Contribution to journalJournal articleResearchpeer-review

Epidemiology
North America
Hospital Mortality
Microbiology
Liver Transplantation

Extracellular Matrix Fragments of the Basement Membrane and the Interstitial Matrix Are Serological Markers of Intestinal Tissue Remodeling and Disease Activity in Dextran Sulfate Sodium Colitis

Lindholm, M., Manon-Jensen, T., Madsen, G. I., Krag, A., Karsdal, M. A., Kjeldsen, J. & Mortensen, J. H., Nov 2019, In : Digestive Diseases and Sciences. 64, 11, p. 3134-3142

Research output: Contribution to journalJournal articleResearchpeer-review

Dextran Sulfate
Colitis
Extracellular Matrix Proteins
Collagen Type III
Matrix Metalloproteinases

Fat-free muscle area measured by magnetic resonance imaging predicts overall survival of patients undergoing radioembolization of colorectal cancer liver metastases

Faron, A., Pieper, C. C., Schmeel, F. C., Sprinkart, A. M., Kuetting, D. L. R., Fimmers, R., Trebicka, J., Schild, H. H., Meyer, C., Thomas, D. & Luetkens, J. A., Sep 2019, In : European Radiology. 29, 9, p. 4709-4717

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Neoplasms
Colorectal Neoplasms
Fats
Muscles
Liver

Fibroblast growth factor 21 is independently associated with severe hepatic steatosis in non-obese HIV-infected patients

Praktiknjo, M., Djayadi, N., Mohr, R., Schierwagen, R., Bischoff, J., Dold, L., Pohlmann, A., Schwarze-Zander, C., Wasmuth, J. C., Boesecke, C., Rockstroh, J. K. & Trebicka, J., Aug 2019, In : Liver International. 39, 8, p. 1514-1520

Research output: Contribution to journalJournal articleResearchpeer-review

HIV
Liver
fibroblast growth factor 21
Dyslipidemias
Hyperlipidemias

Fordøjelseskanalens sygdomme

Schaffalitzky, O. B., Bytzer, P., Havelund, T., Kjeldsen, A. D., Kjeldsen, J. & Rumessen, J., 2019, Medicinsk Kompendium. de Muckadell, O. B. S., Hastrup Svendsen, J. & Vilstrup, H. (eds.). 19. ed. Munksgaard , Vol. 1. p. 939-1087

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

Gene co-expression network analysis of precursor lesions in familial pancreatic cancer

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 20. Sep 2019.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Gene co-expression network analysis of precursor lesions in familial pancreatic cancer

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 29. Aug 2019.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Gene co-expression network analysis of precursor lesions in familial pancreatic cancer

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 13. Nov 2019.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Gene co-expression network analysis of precursor lesions in familial pancreatic cancer (OP308)

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 20. Oct 2019, In : United European Gastroenterology Journal. 7, 8 Suppl., p. 160-161 OP308.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
104 Downloads (Pure)

Home parenteral nutrition increases fat free mass in patients with incurable gastrointestinal cancer. Results of a randomized controlled trial

Obling, S. R., Wilson, B. V., Pfeiffer, P. & Kjeldsen, J., Feb 2019, In : Clinical Nutrition. 38, 1, p. 182-190

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Gastrointestinal Neoplasms
Randomized Controlled Trials
Fats
Quality of Life
Dietetics

Hvorfor skader alkohol leveren?

Johansen, S. & Thiele, M., 21. Nov 2019, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Ulcerative Colitis
Inflammatory Bowel Diseases
Crohn Disease
Psoriatic Arthritis
Psoriasis

Is the total amount as important as localization and type of collagen in liver fibrosis due to steatohepatitis?

Karsdal, M. A., Detlefsen, S., Daniels, S. J., Nielsen, M. J., Krag, A. & Schuppan, D., 25. Sep 2019, In : Hepatology (Baltimore, Md.).

Research output: Contribution to journalReviewResearchpeer-review

Fatty Liver
Liver Cirrhosis
Liver
Coloring Agents

JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms

Rao, T. N., Hansen, N., Hilfiker, J., Rai, S., Majewska, J. M., Leković, D., Gezer, D., Andina, N., Galli, S., Cassel, T., Geier, F., Delezie, J., Nienhold, R., Hao-Shen, H., Beisel, C., Di Palma, S., Dimeloe, S., Trebicka, J., Wolf, D., Gassmann, M. & 10 others, Fan, T. W. M., Lane, A. N., Handschin, C., Dirnhofer, S., Kröger, N., Hess, C., Radimerski, T., Koschmieder, S., Čokić, V. P. & Skoda, R. C., 21. Nov 2019, In : Blood. 134, 21, p. 1832-1846

Research output: Contribution to journalJournal articleResearchpeer-review

Neoplasms
Glycolysis
Hypoglycemia
Erythropoiesis
Oxidative Phosphorylation

Letter re: stratification of meta-analyses based on risk of bias is appropriate and does not induce selection bias

Page, M. J., Hróbjartsson, A., Hansen, C. & Sterne, J. A. C., Nov 2019, In : Journal of Clinical Epidemiology. 115, p. 175-176

Research output: Contribution to journalComment/debateResearchpeer-review

Lever- og galdevejssygdomme

Ott, P., Bendtsen, F., Grønbæk, H., Krag, A. & Larsen, F. S., 2019, Medicinsk Kompendium. de Muckadell, O. B. S., Hastrup Svendsen, J. & Vilstrup, H. (eds.). 19. ed. Munksgaard , Vol. 1. p. 1121-1201

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation

European Alpha1-Liver Study Group, 1. Sep 2019, In : Gastroenterology. 157, 3, p. 705-719.e18

Research output: Contribution to journalJournal articleResearchpeer-review

alpha 1-Antitrypsin Deficiency
Liver Cirrhosis
Mutation
Liver
Liver Diseases

MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding

Redondo-Cerezo, E., Vadillo-Calles, F., Stanley, A. J., Laursen, S., Laine, L., Dalton, H. R., Ngu, J. H., Schultz, M. & Jiménez-Rosales, R., 29. Jul 2019, In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalJournal articleResearchpeer-review

ROC Curve
Confidence Intervals
Databases
Interventional Radiology
Hospital Emergency Service

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L. P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A. M., Manghi, P., Gandini, S., Serrano, D. & 15 others, Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C. M., Brenner, H., Arumugam, M., Bork, P. & Zeller, G., Apr 2019, In : Nature Medicine. 25, 4, p. 679-689

Research output: Contribution to journalJournal articleResearchpeer-review

Metagenome
Meta-Analysis
Colorectal Neoplasms
Genes
Microbiota

Midler mod fordøjelseskanalens sygdomme

Kjeldsen, J., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 295-316

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Natural disease course of Crohn's disease during the first 5 years after diagnosis in a European population-based inception cohort: an Epi-IBD study

Burisch, J., Kiudelis, G., Kupcinskas, L., Kievit, H. A. L., Andersen, K. W., Andersen, V., Salupere, R., Pedersen, N., Kjeldsen, J., D'Incà, R., Valpiani, D., Schwartz, D., Odes, S., Olsen, J., Nielsen, K. R., Vegh, Z., Lakatos, P. L., Toca, A., Turcan, S., Katsanos, K. H. & 27 others, Christodoulou, D. K., Fumery, M., Gower-Rousseau, C., Zammit, S. C., Ellul, P., Eriksson, C., Halfvarson, J., Magro, F. J., Duricova, D., Bortlik, M., Fernandez, A., Hernández, V., Myers, S., Sebastian, S., Oksanen, P., Collin, P., Goldis, A., Misra, R., Arebi, N., Kaimakliotis, I. P., Nikuina, I., Belousova, E., Brinar, M., Cukovic-Cavka, S., Langholz, E., Munkholm, P. & Epi-IBD group, 1. Mar 2019, In : Gut. 68, 3, p. 423-433

Research output: Contribution to journalJournal articleResearchpeer-review

Crohn Disease
Population
Immunologic Factors
Eastern Europe
Mesalamine
17 Downloads (Pure)

Natural Disease Course of Ulcerative Colitis During the First Five Years of Follow-up in a European Population-based Inception Cohort-An Epi-IBD Study

Epi-IBD group, 1. Feb 2019, In : Journal of Crohn's and Colitis. 13, 2, p. 198–208

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Ulcerative Colitis
Population
Immunologic Factors
Colitis
Cohort Studies

Pankreassygdomme

Olesen, S. S. & Schaffalitzky, O. B., 2019, Medicinsk Kompendium. de Muckadell, O. B. S., Hastrup Svendsen, J. & Vilstrup, H. (eds.). 19. ed. Munksgaard , Vol. 1. p. 1089-1120

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

36 Downloads (Pure)

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis

Queck, A., Thomas, D., Jansen, C., Schreiber, Y., Rüschenbaum, S., Praktiknjo, M., Schwarzkopf, K. M., Mücke, M. M., Schierwagen, R., Uschner, F. E., Meyer, C., Clària, J., Zeuzem, S., Geisslinger, G., Trebicka, J. & Lange, C. M., 23. Oct 2019, In : PLOS ONE. 14, 10, 12 p., e0222840.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
liver cirrhosis
Portal Vein
Coagulation
coagulation
Liver Cirrhosis