Clinical Pharmacology and Pharmacy

  • J. B. Winsløws Vej 19, 2.

    5000 Odense C

Research Output 1981 2019

2019

20 years of major and minor malformations in Danish Health Registries: A descriptive study

Damkier, P., Bliddal, M., Pottegård, A., Hallas, J. & Broe, A., 27. Aug 2019.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Acute exercise increases plasma levels of muscle-derived microvesicles carrying fatty acid transport proteins

Nielsen, M. H., Sabaratnam, R., Pedersen, A. J. T., Højlund, K. & Handberg, A., 1. Oct 2019, In : The Journal of clinical endocrinology and metabolism. 104, 10, p. 4804-4814

Research output: Contribution to journalJournal articleResearchpeer-review

Fatty Acid Transport Proteins
Muscle
Skeletal Muscle
Exercise
Plasmas

Adherence to Prescribed Drugs Among 65-74 Year Old Men Diagnosed with Abdominal Aortic Aneurysm or Peripheral Arterial Disease in a Screening Trial: A VIVA Substudy

Qvist, I., Søgaard, R., Lindholt, J. S., Lorentzen, V., Hallas, J. & Frost, L., Mar 2019, In : European Journal of Vascular and Endovascular Surgery. 57, 3, p. 442-450

Research output: Contribution to journalJournal articleResearchpeer-review

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Abdominal Aortic Aneurysm
Pharmaceutical Preparations
Prescriptions
Population

A model to predict the risk of aspirin/NSAID-related upper gastrointestinal bleeding for the individual patient

Petersen, J., Møller Hansen, J., de Muckadell, O. B. S., Dall, M. & Hallas, J., 25. Nov 2019, In : Basic & Clinical Pharmacology & Toxicology.

Research output: Contribution to journalJournal articleResearchpeer-review

Aspirin
Anti-Inflammatory Agents
Pharmaceutical Preparations
Ulcer
Incidence
7 Downloads (Pure)

Angiotensin II receptor blockers are safe in patients with prior angioedema related to angiotensin-converting enzyme inhibitors - a nationwide registry-based cohort study

Rasmussen, E. R., Pottegård, A., Bygum, A., von Buchwald, C., Homøe, P. & Hallas, J., May 2019, In : Journal of Internal Medicine. 285, 5, p. 553-561

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Angiotensin Receptor Antagonists
Registries
Cohort Studies
Propensity Score
Adrenergic beta-Antagonists

Antidepressant drug use and subdural hematoma risk

Gaist, D., García Rodríguez, L. A., Hald, S. M., Hellfritzsch, M., Poulsen, F. R., Halle, B., Hallas, J. & Pottegård, A., 14. Oct 2019, In : Journal of Thrombosis and Haemostasis.

Research output: Contribution to journalJournal articleResearchpeer-review

Serotonin Uptake Inhibitors
Pharmaceutical Preparations
Population Control
Registries
Case-Control Studies
111 Downloads (Pure)

Antidepressant use in Denmark, Germany, Spain, and Sweden between 2009 and 2014: Incidence and comorbidities of antidepressant initiators

Forns, J., Pottegård, A., Reinders, T., Poblador-Plou, B., Morros, R., Brandt, L., Cainzos-Achirica, M., Hellfritzsch, M., Schink, T., Prados-Torres, A., Giner-Soriano, M., Hägg, D., Hallas, J., Cortés, J., Jacquot, E., Deltour, N., Perez-Gutthann, S., Pladevall, M. & Reutfors, J., 2019, In : Journal of Affective Disorders. 249, p. 242-252

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Denmark
Germany
Comorbidity
Incidence
S 20098

Antihistamines and ovarian cancer survival: nationwide cohort study and in vitro cell viability assay

Verdoodt, F., Dehlendorff, C., Jäättelä, M., Strauss, R., Pottegård, A., Hallas, J., Friis, S. & Kjaer, S. K., 5. Nov 2019, In : National Cancer Institute. Journal (Print).

Research output: Contribution to journalJournal articleResearchpeer-review

Histamine Antagonists
Ovarian Neoplasms
Cell Survival
Cohort Studies
Pharmaceutical Preparations
5 Downloads (Pure)

Antihistamine use and risk of ovarian cancer: A population-based case-control study

Verdoodt, F., Pottegård, A., Dehlendorff, C., Jäättelä, M., Hallas, J., Friis, S. & Kjaer, S. K., 1. Feb 2019, In : Maturitas. 120, p. 47-52

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Histamine Antagonists
Ovarian Neoplasms
Case-Control Studies
Odds Ratio
Population

A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24

Mirza, M. R., Bergmann, T. K., Mau-Sørensen, M., Christensen, R. D., Åvall-Lundqvist, E., Birrer, M. J., Jørgensen, M., Roed, H., Malander, S., Nielsen, F., Lassen, U., Brøsen, K., Bjørge, L. & Mäenpää, J., Oct 2019, In : Cancer Chemotherapy and Pharmacology. 84, 4, p. 791-798

Research output: Contribution to journalJournal articleResearchpeer-review

Platinum
Angiogenesis Inhibitors
Germ-Line Mutation
Ovarian Neoplasms
Disease-Free Survival

Apixaban or rivaroxaban in the treatment of acute venous thromboembolism?

Hellfritzsch, M., Grove, E. L. & Adelborg, K., Sep 2019, In : Journal of Translational Medicine. 7, Supp.l 6, 4 p., S206.

Research output: Contribution to journalEditorialResearch

18 Downloads (Pure)

A review of the Ghana National Health Insurance Scheme claims database: possibilities and limits for drug utilization research

Ankrah, D., Hallas, J., Odei, J., Asenso-Boadi, F., Dsane-Selby, L. & Donneyong, M., Jan 2019, In : Basic & Clinical Pharmacology & Toxicology. 124, 1, p. 18-27

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Health insurance
Drug Utilization
Ghana
National Health Programs
Databases
21 Downloads (Pure)

Association between diabetes and oncological outcomes in patients undergoing neoadjuvant chemo-radiotherapy for rectal cancer

Fransgaard, T., Hallas, J., Thygesen, L. C. & Gögenur, I., 1. Mar 2019, In : Surgical Oncology. 28, p. 62-66

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Rectal Neoplasms
Disease-Free Survival
Propensity Score
Neoadjuvant Therapy
Denmark

Association of Statin Use and Oncological Outcomes After Neoadjuvant Radiotherapy in Patients With Rectal Cancer

Fransgaard, T., Hallas, J., Thygesen, L. C. & Gögenur, I., Apr 2019, In : Anticancer Research. 39, 4, p. 2177-2182

Research output: Contribution to journalJournal articleResearchpeer-review

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Rectal Neoplasms
Disease-Free Survival
Propensity Score
Cohort Studies

Associations between adult height and type 2 diabetes mellitus: A systematic review and meta-analysis of observational studies

Shrestha, S., Rasmussen, S. H., Pottegård, A., Ängquist, L. H., Jess, T., Allin, K. H., Bjerregaard, L. G. & Baker, J. L., Jul 2019, In : Journal of Epidemiology and Community Health. 73, 7, p. 681-688

Research output: Contribution to journalReviewResearchpeer-review

Type 2 Diabetes Mellitus
Meta-Analysis
Cohort Studies
Cross-Sectional Studies
PubMed

Associations of exposure to perfluoroalkyl substances with thyroid hormone concentrations and birth size

Xiao, C., Grandjean, P., Valvi, D., Nielsen, F., Jensen, T. K., Weihe, P. & Oulhote, Y., 29. Oct 2019, In : The Journal of clinical endocrinology and metabolism.

Research output: Contribution to journalJournal articleResearchpeer-review

perfluorooctanoic acid
Thyrotropin
Thyroid Hormones
Mothers
Linear regression

Baseline findings of the population-based, randomized, multifaceted Danish cardiovascular screening trial (DANCAVAS) of men aged 65-74 years

Lindholt, J. S., Rasmussen, L. M., Søgaard, R., Lambrechtsen, J., Steffensen, F. H., Frost, L., Egstrup, K., Urbonaviciene, G., Busk, M., Olsen, M. H., Hallas, J. & Diederichsen, A. C., Jun 2019, In : The British journal of surgery. 106, 7, p. 862-871

Research output: Contribution to journalJournal articleResearchpeer-review

Population
Iliac Aneurysm
Thoracic Aortic Aneurysm
Abdominal Aortic Aneurysm
Hyperlipidemias
1 Downloads (Pure)

Bisphosphonate use and risk of renal cell carcinoma: a population-based case-control study

Chung, B. I., Hellfritzsch, M., Ulrichsen, S. P., Sørensen, H. T. & Ehrenstein, V., 1. May 2019, In : Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 642-646

Research output: Contribution to journalLetterResearchpeer-review

Open Access
File
Diphosphonates
Case-Control Studies
Cells
Population
Odds Ratio

Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study

Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, F. K. & Sørensen, H. T., 1. Aug 2019, In : Journal of Diabetes. 11, 8, p. 690-694

Research output: Contribution to journalJournal articleResearchpeer-review

Drug Utilization
Denmark
Prescriptions
Drug Combinations
Diabetes Complications
54 Downloads (Pure)

Concise Review: Patency of Small-Diameter Tissue-Engineered Vascular Grafts: A Meta-Analysis of Preclinical Trials

Skovrind, I., Harvald, E. B., Juul Belling, H., Jørgensen, C. D., Lindholt, J. S. & Andersen, D. C., Jul 2019, In : Stem Cells Translational Medicine. 8, 7, p. 671-680

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
Meta-Analysis
Logistic Models
Guidelines
Rabbits
57 Downloads (Pure)

Conization and healthcare use: a population-based register study

Frederiksen, M. E., Vázquez-Prada Baillet, M., Jensen, P. T., Rygaard, C., Hallas, J. & Lynge, E., Mar 2019, In : European Journal of Cancer Prevention. 28, 2, p. 124–130

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Conization
Registries
Delivery of Health Care
General Hospitals
General Practitioners

Deprescribing @ Hospital Pharmacy Funen

Lundby, C., Ryg, J., Simonsen, T., Søndergaard, J., Pottegård, A. & Lauridsen, H. H., 17. Jan 2019.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Chronic Obstructive Pulmonary Disease
Adrenal Cortex Hormones
Drug Utilization
Cholinergic Antagonists
Drug Combinations
Open Access
Vitamin K
Anticoagulants
Meta-Analysis
Safety
Confidence Intervals

Effect of a medicines management model on medication-related readmissions in older patients admitted to a medical acute admission unit: A randomized controlled trial

Graabaek, T., Hedegaard, U., Christensen, M. B., Clemmensen, M. H., Knudsen, T. & Aagaard, L., Feb 2019, In : Journal of Evaluation in Clinical Practice Online. 25, 1, p. 88-96

Research output: Contribution to journalJournal articleResearchpeer-review

Randomized Controlled Trials
Pharmacists
Inpatients
Interviews
Patient Admission

Efficacy of bronchial thermoplasty in patients with severe asthma

Madsen, H., Henriksen, D. P., Backer, V., Siersted, H. C., Bjerring, N. & Ulrik, C. S., 18. Oct 2019, In : Journal of Asthma.

Research output: Contribution to journalJournal articleResearchpeer-review

Adrenal Cortex Hormones
Quality of Life
Surveys and Questionnaires
Delivery of Health Care
Safety

Exercise induction of key transcriptional regulators of metabolic adaptation in muscle is preserved in type 2 diabetes

Sabaratnam, R., Pedersen, A. J., Eskildsen, T. V., Kristensen, J. M., Wojtaszewski, J. F. P. & Højlund, K., 1. Oct 2019, In : The Journal of clinical endocrinology and metabolism. 104, 10, p. 4909-4920

Research output: Contribution to journalJournal articleResearchpeer-review

Medical problems
Type 2 Diabetes Mellitus
Muscle
Exercise
Muscles

Exposure to phthalate-containing prescription drugs and the risk of colorectal adenocarcinoma: A Danish nationwide case-control study

Ennis, Z. N., Pottegård, A., Ahern, T. P., Hallas, J. & Damkier, P., 2019, In : Pharmacoepidemiology and Drug Safety. 28, 4, p. 528-535

Research output: Contribution to journalJournal articleResearchpeer-review

Case-Control Studies
Colorectal Neoplasms
Excipients
Pharmaceutical Preparations
phthalic acid

Farmakogenetik/farmakogenomik

Brøsen, K., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 119-128

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

117 Downloads (Pure)

First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus

Ravnsborg, T., Svaneklink, S., Andersen, L. L. T., Larsen, M. R., Jensen, D. M. & Overgaard, M., 27. Mar 2019, In : PLOS ONE. 14, 3, 13 p., e0214457.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
gestational diabetes
Gestational Diabetes
First Pregnancy Trimester
Medical problems
proteomics

Frequency of undocumented medication discrepancies in discharge letters after hospitalization of older patients: a clinical record review study

Graabæk, T., Terkildsen, B. G., Lauritsen, K. E. & Almarsdóttir, A. B., 2019, In : Therapeutic Advances in Drug Safety.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Patient Transfer
Inpatients
Patient Safety
Documentation
Life Expectancy
Delivery of Health Care
Patient Advocacy
Qualitative Research
Checklist

Hepatic exposure of metformin in patients with non-alcoholic fatty liver disease

Sundelin, E. I. O., Gormsen, L. C., Heebøll, S., Vendelbo, M. H., Jakobsen, S., Munk, O. L., Feddersen, S., Brøsen, K., Hamilton-Dutoit, S. J., Pedersen, S. B., Grønbaek, H. & Jessen, N., Aug 2019, In : British Journal of Clinical Pharmacology. 85, 8, p. 1761-1770

Research output: Contribution to journalJournal articleResearchpeer-review

Liver
Cations
Type 2 Diabetes Mellitus
Insulin Resistance
Western World

Hydrochlorothiazide Use and Increased Squamous Cell Carcinoma Burden in a High-Risk Mohs Population: A Cross-Sectional Study

Han, S., Wolfe, C. M., Angnardo, L., Pedersen, S. A., Gaist, D., Pottegård, A. & Cognetta, A. B., 8. Mar 2019, In : Dermatologic Surgery.

Research output: Contribution to journalLetterResearchpeer-review

63 Downloads (Pure)

Hydrochlorothiazide use and risk for Merkel cell carcinoma and malignant adnexal skin tumors: A nationwide case-control study

Pedersen, S. A., Johannesdottir Schmidt, S. A., Hölmich, L. R., Friis, S., Pottegård, A. & Gaist, D., Feb 2019, In : Journal of the American Academy of Dermatology. 80, 2, p. 460-465.e9

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Merkel Cell Carcinoma
Case-Control Studies
Skin
Confidence Intervals
Neoplasms
50 Downloads (Pure)

Identification of potential carcinogenic and chemopreventive effects of prescription drugs: A protocol for a Norwegian registry-based study

Andreassen, B. K., Støer, N. C., Martinsen, J. I., Ursin, G., Weiderpass, E., Thoresen, G. H., Debernard, K. B., Karlstad, Ø., Pottegard, A. & Friis, S., 8. Apr 2019, In : BMJ Open. 9, 4, 7 p., e028504.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Registries
Neoplasms
Norway
Pharmaceutical Preparations
Pharmacovigilance

Increased risk of major adverse cardiac events following the onset of acute exacerbations of COPD

Reilev, M., Pottegård, A., Lykkegaard, J., Søndergaard, J., Ingebrigtsen, T. S. & Hallas, J., 1. Dec 2019, In : Respirology. 24, 12, p. 1183-1190

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Obstructive Pulmonary Disease
Odds Ratio
Cross-Over Studies
45 Downloads (Pure)

Interaction between warfarin and cannabis

Damkier, P., Lassen, D., Christensen, M. M. H., Madsen, K. G., Hellfritzsch, M. & Pottegård, A., Jan 2019, In : Basic & Clinical Pharmacology & Toxicology. 124, 1, p. 28-31

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
International Normalized Ratio
Warfarin
Cannabis
Dronabinol
Cannabinoids
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Clarithromycin
Pravastatin
Lovastatin
Area Under Curve

In utero exposure to antibiotics and risk of congenital malformations: a population-based study

Damkier, P., Brønniche, L. M. S., Korch-Frandsen, J. F. B. & Broe, A., 2019, In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalJournal articleResearchpeer-review

Odds Ratio
Confidence Intervals
First Pregnancy Trimester
Population
Denmark
Dicloxacillin
Floxacillin
Heart Valves
Warfarin
Confidence Intervals

Lægemiddelbivirkninger

Hallas, J., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 975-984

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Lægemiddelforbrug

Hallas, J., Andersen, M. & Brøsen, K., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 1138-1142

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Lægemiddelinteraktioner

Bergmann, T. K., Brøsen, K. & Christensen, H. R., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 992-1000

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Lægemidler med virkning på hæmostasen

Poulsen, M. H. & Schougaard Christensen, M. L., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 416-443

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Lægemidlers elimination

Brøsen, K., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 100-118

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Lægemidlers skæbne i organismen

Brøsen, K., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 65-99

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Metformin increases endogenous glucose production in non-diabetic individuals and individuals with recent-onset type 2 diabetes

Gormsen, L. C., Søndergaard, E., Christensen, N. L., Brøsen, K., Jessen, N. & Nielsen, S., 1. Jul 2019, In : Diabetologia. 62, 7, p. 1251-1256

Research output: Contribution to journalJournal articleResearchpeer-review

Type 2 Diabetes Mellitus
Placebos
Glucose Clamp Technique
Random Allocation
Glucagon

Morbidity and mortality among older people admitted to nursing home

Reilev, M., Lundby, C., Jensen, J., Larsen, S. P., Hoffmann, H. & Pottegård, A., 25. Nov 2019, In : Age and Ageing.

Research output: Contribution to journalJournal articleResearchpeer-review

Nursing Homes
Comorbidity
Delivery of Health Care
Registries
Health

Multi-drug resistance protein 2 (MRP2) expression, adjuvant tamoxifen therapy, and risk of breast cancer recurrence: a Danish population-based nested case-control study

Hjorth, C. F., Nielsen, A. S., Sørensen, H. T., Lash, T. L., Damkier, P., Hamilton-Dutoit, S. & Cronin-Fenton, D., 1. Feb 2019, In : Acta Oncologica. 58, 2, p. 168-174

Research output: Contribution to journalJournal articleResearchpeer-review

Multiple Drug Resistance
Case-Control Studies
Population
Proteins
Confidence Intervals