Research Output

2020

2D shear wave liver elastography by aixplorer to detect portal hypertension in cirrhosis: an individual patient data meta‐analysis

Thiele, M., Hugger, M. B., Kim, Y., Rautou, PE., Elkrief, L., Jansen, C., Verlinden, W., Allegretti, G., Israelsen, M., Stefanescu, H., Piscaglia, F., García‐Pagán, J. C., Franque, S., Berzigotti, A., Castera, L., Jeong, W. K., Trebicka, J. & Krag, A., 1. Jun 2020, In : Liver International. 40, 6, p. 1435-1446

Research output: Contribution to journalJournal articleResearchpeer-review

Addition of trans-fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis

Daniels, S. J., Leeming, D. J., Detlefsen, S., Bruun, M. F., Hjuler, S. T., Henriksen, K., Hein, P., Krag, A., Karsdal, M. A., Nielsen, M. J., Brockbank, S. & Cruwys, S., Mar 2020, In : American journal of physiology. Gastrointestinal and liver physiology. 318, 3, p. G410-G418

Research output: Contribution to journalJournal articleResearchpeer-review

Administrative procedurer ved godkendelse af nye lægemidler

Ainsworth, M. A. & Sarac, S. B., 2020, In : Ugeskrift for Laeger. 182, 5, V10180677.

Research output: Contribution to journalJournal articleResearchpeer-review

A Fragment of Collagen Type VI alpha-3 chain is Elevated in Serum from Patients with Gastrointestinal Disorders

Holm Nielsen, S., Mortensen, J. H., Willumsen, N., Rasmussen, D. G. K., Mogensen, D. J., Di Sabatino, A., Mazza, G., Jørgensen, L. N., Giuffrida, P., Pinzani, M., Klinge, L., Kjeldsen, J., Leeming, D. J., Karsdal, M. A. & Genovese, F., 3. Apr 2020, In : Scientific Reports. 10, 8 p., 5910.

Research output: Contribution to journalJournal articleResearchpeer-review

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Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis

Queck, A., Fink, A. F., Sirait-Fischer, E., Rüschenbaum, S., Thomas, D., Snodgrass, R. G., Geisslinger, G., Baba, H. A., Trebicka, J., Zeuzem, S., Weigert, A., Lange, C. M. & Brüne, B., Jul 2020, In : Frontiers in Immunology. 11, 13 p., 1447.

Research output: Contribution to journalJournal articleResearchpeer-review

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Anti-TNF Therapy in Pregnant Women With Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes

Julsgaard, M., Hvas, C. L., Gearry, R. B., Gibson, P. R., Fallingborg, J., Sparrow, M. P., Bibby, B. M., Connell, W. R., Brown, S. J., Kamm, M. A., Lawrance, I. C., Vestergaard, T., Svenningsen, L., Baekdal, M., Kammerlander, H., Walsh, A., Boysen, T., Bampton, P., Radford-Smith, G., Kjeldsen, J. & 10 others, Andrews, J. M., Subramaniam, K., Moore, G. T., Jensen, N. M., Connor, S. J., Wildt, S., Wilson, B., Ellard, K., Christensen, L. A. & Bell, S. J., 1. Jan 2020, In : Inflammatory Bowel Diseases. 26, 1, p. 93-102

Research output: Contribution to journalJournal articleResearchpeer-review

Cardiodynamic state is associated with systemic inflammation and fatal acute-on-chronic liver failure

Praktiknjo, M., Monteiro, S., Grandt, J., Kimer, N., Madsen, J. L., Werge, M. P., William, P., Brol, M. J., Turco, L., Schierwagen, R., Chang, J., Klein, S., Uschner, F. E., Welsch, C., Moreau, R., Schepis, F., Bendtsen, F., Gluud, L. L., Møller, S. & Trebicka, J., Jun 2020, In : Liver International. 40, 6, p. 1457-1466

Research output: Contribution to journalJournal articleResearchpeer-review

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Challenges and opportunities for IBD drug development: From early stage to regulatory approval

Danese, S., Schabel, E., Ainsworth, M. A. & Peyrin-Biroulet, L., Jul 2020, In : GUT. 69, 7, p. 1157-1161

Research output: Contribution to journalReviewResearchpeer-review

Collagen type IV remodeling gender-specifically predicts mortality in decompensated liver cirrhosis

Praktiknjo, M., Lehmann, J., Nielsen, M. J., Schierwagen, R., Meyer, C., Thomas, D., Strassburg, C. P., Bendtsen, F., Møller, S., Krag, A., Karsdal, M., Leeming, D. J. & Trebicka, J., Jan 2020, In : Zeitschrift fuer Gastroenterologie. 57, 1, p. e37-e38

Research output: Contribution to journalConference abstract in journalResearch

Cost-effectiveness of non-invasive screening for alcohol-related liver fibrosis

Galaxy Consortium, Jun 2020, In : Hepatology (Baltimore, Md.). 71, 6, p. 2093-2104

Research output: Contribution to journalJournal articleResearchpeer-review

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Describing the fecal metabolome in cryogenically collected samples from healthy participants

Trošt, K., Ahonen, L., Suvitaival, T., Christiansen, N., Nielsen, T., Thiele, M., Jacobsen, S., Krag, A., Rossing, P., Hansen, T., Dragsted, L. O. & Legido-Quigley, C., 21. Jan 2020, In : Scientific Reports. 10, 8 p., 885.

Research output: Contribution to journalJournal articleResearchpeer-review

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Dobutamine reverses the cardio-suppressive effects of terlipressin without improving renal function in cirrhosis and ascites: a randomized controlled trial

Israelsen, M., Dahl, E. K., Madsen, B. S., Wiese, S., Bendtsen, F., Møller, S., Fialla, A. D., Jensen, B. L. & Krag, A., 1. Feb 2020, In : American journal of physiology. Gastrointestinal and liver physiology. 318, 2, p. G313-G321

Research output: Contribution to journalJournal articleResearchpeer-review

Effect of post-ERCP cholecystectomy vs. primary ERCP alone on the rate of recurrent common bile duct stones

Tan, M., Schaffalitzky, O. B. & Laursen, S. B., Jun 2020, In : Gastrointestinal Endoscopy. 91, 6, Suppl., p. AB360-AB361 Su1518.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Effect of post-ERCP cholecystectomy vs. primary ERCP alone on the rate of recurrent common bile duct stones (Su1518)

Tan, M., Schaffalitzky, O. B. & Laursen, S. B., 3. May 2020.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

European Reference Network for Rare Vascular Diseases (VASCERN) position statement on cerebral screening in adults and children with hereditary haemorrhagic telangiectasia (HHT)

Eker, O. F., Boccardi, E., Sure, U., Patel, M. C., Alicante, S., Alsafi, A., Coote, N., Droege, F., Dupuis, O., Fialla, A. D., Jones, B., Kariholu, U., Kjeldsen, A. D., Lefroy, D., Lenato, G. M., Mager, H. J., Manfredi, G., Nielsen, T. H., Pagella, F., Post, M. C. & 8 others, Rennie, C., Sabbà, C., Suppressa, P., Toerring, P. M., Ugolini, S., Buscarini, E., Dupuis-Girod, S. & Shovlin, C. L., 29. Jun 2020, In : Orphanet Journal of Rare Diseases. 15, 10 p., 165.

Research output: Contribution to journalJournal articleResearchpeer-review

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Expression profiling of candidate genes associated with pancreatic cancer

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 6. Feb 2020.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Gene co-expression network analysis of precursor lesions in familial pancreatic cancer

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., May 2020, In : Gastroenterology. 158, 6, p. S-1137–S-1138 2 p., Tu1614.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Gene Expression Network Analysis of Precursor Lesions in Familial Pancreatic Cancer

Tan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 5. Aug 2020, In : Journal of Pancreatic Cancer. 6, 1, p. 73-84 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Health-care costs of inflammatory bowel disease in a pan-European, community-based, inception cohort during 5 years of follow-up: a population-based study

Epi-IBD group, May 2020, In : The Lancet Gastroenterology & Hepatology. 5, 5, p. 454-464

Research output: Contribution to journalJournal articleResearchpeer-review

Hereditær pankreatitis

Translated title of the contribution: Hereditary pancreatitisTan, M., Schaffalitzky, O. B. & Jørgensen, M. T., 10. Feb 2020, In : Ugeskrift for Laeger. 182, V11190676.

Research output: Contribution to journalJournal articleResearchpeer-review

How do I establish a stool bank for fecal microbiota transplantation within the blood- and tissue transplant service?

Kragsnaes, M. S., Nilsson, A. C., Kjeldsen, J., Holt, H. M., Rasmussen, K. F., Georgsen, J., Ellingsen, T. & Holm, D. K., Jun 2020, In : Transfusion. 60, 6, p. 1135-1141

Research output: Contribution to journalComment/debateResearchpeer-review

Is the Total Amount as Important as Localization and Type of Collagen in Liver Fibrosis Attributable to Steatohepatitis?

Karsdal, M. A., Detlefsen, S., Daniels, S. J., Nielsen, M. J., Krag, A. & Schuppan, D., Jan 2020, In : Hepatology (Baltimore, Md.). 71, 1, p. 346-351

Research output: Contribution to journalReviewResearchpeer-review

Ketamine as an Anesthetic for Patients with Acute Brain Injury: A Systematic Review

Gregers, M. C. T., Mikkelsen, S., Lindvig, K. P. & Brøchner, A. C., 23. Apr 2020, In : Neurocritical Care.

Research output: Contribution to journalReviewResearchpeer-review

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Krav til dokumentation ved godkendelse af nye lægemidler

Ainsworth, M. A. & Sarac, S. B., 2020, In : Ugeskrift for Laeger. 182, 5, V10180678.

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers

European Alpha-1 Liver Study Group, 4. May 2020, In : Gastroenterology.

Research output: Contribution to journalJournal articleResearchpeer-review

Liver Transplantation for Acute-on-Chronic Liver Failure: Science or Fiction?

Trebicka, J., Sundaram, V., Moreau, R., Jalan, R. & Arroyo, V., 1. Jul 2020, In : Liver Transplantation. 26, 7, p. 906-915

Research output: Contribution to journalReviewResearchpeer-review

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MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding

Redondo-Cerezo, E., Vadillo-Calles, F., Stanley, A. J., Laursen, S., Laine, L., Dalton, H. R., Ngu, J. H., Schultz, M. & Jiménez-Rosales, R., Jan 2020, In : Journal of Gastroenterology and Hepatology (Australia). 35, 1, p. 82-89

Research output: Contribution to journalJournal articleResearchpeer-review

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Medical care setting is associated with survival in acute upper gastro-intestinal bleeding: A cohort study

Marmo, R., Soncini, M., Marmo, C., Borbjerg Laursen, S., Gralnek, I. M. & Stanley, A. J., May 2020, In : Digestive and Liver Disease. 52, 5, p. 561-565

Research output: Contribution to journalJournal articleResearchpeer-review

Mortality in biopsy-proven alcohol-related liver disease: A population-based nationwide cohort study of 3453 patients

Hagström, H., Thiele, M., Roelstraete, B., Söderling, J. & Ludvigsson, J. F., 1. Jan 2020, (Accepted/In press) In : GUT. 32220902.

Research output: Contribution to journalJournal articleResearchpeer-review

Precipitants of Acute-on-Chronic Liver Failure: An Opportunity for Preventative Measures to Improve Outcomes

Cullaro, G., Sharma, R., Trebicka, J., Cárdenas, A. & Verna, E. C., Feb 2020, In : Liver Transplantation. 26, 2, p. 283-293 11 p.

Research output: Contribution to journalReviewResearchpeer-review

Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar-associated protein 4

Galaxy Consortium, Jul 2020, In : Liver International. 40, 7, p. 1701-1712

Research output: Contribution to journalJournal articleResearchpeer-review

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Recent advances in alcohol-related liver disease (ALD): Summary of a Gut round table meeting

Avila, M. A., Dufour, J. F., Gerbes, A. L., Zoulim, F., Bataller, R., Burra, P., Cortez-Pinto, H., Gao, B., Gilmore, I., Mathurin, P., Moreno, C., Poznyak, V., Schnabl, B., Szabo, G., Thiele, M. & Thursz, M. R., Apr 2020, In : GUT. 69, 4, p. 764-780

Research output: Contribution to journalJournal articleResearchpeer-review

Recent advances in practical methods for liver cell biology: A short overview

Torres, S., Abdullah, Z., Brol, M. J., Hellerbrand, C., Fernandez, M., Fiorotto, R., Klein, S., Königshofer, P., Liedtke, C., Lotersztajn, S., Nevzorova, Y. A., Schierwagen, R., Reiberger, T., Uschner, F. E., Tacke, F., Weiskirchen, R. & Trebicka, J., 2020, In : International Journal of Molecular Sciences . 21, 6, 2027.

Research output: Contribution to journalReviewResearchpeer-review

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Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial

Godskesen, L. E., Lassen, T. R., Jespersen, N. R., Siersbæk, M., Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G., Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J., 12. Jun 2020, In : Scientific Reports. 10, 15 p., 9537.

Research output: Contribution to journalJournal articleResearchpeer-review

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Sarcopenic obesity and associations with mortality in older women and men - a prospective observational study

von Berens, B., Obling, S. R., Nydahl, M., Koochek, A., Lissner, L., Skoog, I., Frändin, K., Skoglund, E., Rothenberg, E. & Cederholm, T., Jun 2020, In : BMC Geriatrics. 20, 1, 10 p., 199.

Research output: Contribution to journalJournal articleResearchpeer-review

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Serological biomarkers of interstitial matrix and basement membrane remodelling correlate the Modified Mayo Endoscopic Score (mMES) for ulcerative colitis

Mortensen, J., Godskesen, L. E., Lindholm, M., Krag, A., Karsdal, M. A., Manon-Jensen, T. & Kjeldsen, J., Jan 2020, In : Journal of Crohn's and Colitis. 14, Suppl. 1, p. S260-S261 1 p.

Research output: Contribution to journalConference abstract in journalResearch

Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis

Benz, F., Bogen, A., Praktiknjo, M., Jansen, C., Meyer, C., Wree, A., Demir, M., Loosen, S., Vucur, M., Schierwagen, R., Tacke, F., Trebicka, J. & Roderburg, C., Apr 2020, In : PLOS ONE. 15, 4, 13 p., e0231701.

Research output: Contribution to journalJournal articleResearchpeer-review

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Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS

Torner, M., Mangal, A., Scharnagl, H., Jansen, C., Praktiknjo, M., Queck, A., Gu, W., Schierwagen, R., Lehmann, J., Uschner, F. E., Graf, C., Strassburg, C. P., Fernandez, J., Stojakovic, T., Woitas, R. & Trebicka, J., 1. Jan 2020, In : Liver International. 40, 1, p. 186-193

Research output: Contribution to journalJournal articleResearchpeer-review

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Short-term western diet aggravates non-alcoholic fatty liver disease (NAFLD) with portal hypertension in TGR(mREN2)27 rats

Cremonese, C., Schierwagen, R., Uschner, F. E., Torres, S., Tyc, O., Ortiz, C., Schulz, M., Queck, A., Kristiansen, G., Bader, M., Sauerbruch, T., Weiskirchen, R., Walther, T., Trebicka, J. & Klein, S., May 2020, In : International Journal of Molecular Sciences . 21, 9, 14 p., 3308.

Research output: Contribution to journalJournal articleResearchpeer-review

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Skrumper en skrumpelever virkelig?

Thorhauge, K. & Thiele, M., 15. Feb 2020, In : Videnskab.dk.

Research output: Contribution to journalJournal articleCommunication

Statiner er sikre ved leversygdom og har muligvis en gunstig effekt

Translated title of the contribution: Statins are safe in patients with liver diseases and may have a beneficial effectBalle Hugger, M., Bastrup Israelsen, M., Dalby Hansen, C. & Krag, A., 2020, In : Ugeskrift for Laeger. 182, 7, V11180794.

Research output: Contribution to journalJournal articleResearchpeer-review

Steatosis Assessment with Controlled Attenuation Parameter (CAP) in Various Diseases.

Wernberg, C., Thiele, M. & Balle Hugger, M., 3. Jun 2020, Liver Elastography. Sebastian, M. (ed.). Springer, p. 441-457

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis

Queck, A., Bode, H., Uschner, F. E., Brol, M. J., Graf, C., Schulz, M., Jansen, C., Praktiknjo, M., Schierwagen, R., Klein, S., Trautwein, C., Wasmuth, H. E., Berres, M. L., Trebicka, J. & Lehmann, J., 11. Mar 2020, In : Frontiers in Immunology. 11, March, 8 p., 354.

Research output: Contribution to journalJournal articleResearchpeer-review

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The Development and Outcome of Acute-on-Chronic Liver Failure After Surgical Interventions

Klein, L. M., Chang, J., Gu, W., Manekeller, S., Jansen, C., Lingohr, P., Praktiknjo, M., Kalf, J. C., Schulz, M., Spengler, U., Strassburg, C., Cardenas, A., Arroyo, V. & Trebicka, J., Feb 2020, In : Liver Transplantation. 26, 2, p. 227-237

Research output: Contribution to journalJournal articleResearchpeer-review

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The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease

Schierwagen, R., Uschner, F. E., Ortiz, C., Torres, S., Brol, M. J., Tyc, O., Gu, W., Grimm, C., Zeuzem, S., Plamper, A., Pfeifer, P., Zimmer, S., Welsch, C., Schaefer, L., Rheinwalt, K. P., Clària, J., Arroyo, V., Trebicka, J. & Klein, S., Jul 2020, In : Frontiers in Immunology. 11, 1352.

Research output: Contribution to journalJournal articleResearchpeer-review

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The Shock Index is not accurate at predicting outcomes in patients with upper gastrointestinal bleeding

Saffouri, E., Blackwell, C., Laursen, S. B., Laine, L., Dalton, H. R., Ngu, J., Shultz, M., Norton, R. & Stanley, A. J., Jan 2020, In : Alimentary Pharmacology and Therapeutics. 51, 2, p. 253-260

Research output: Contribution to journalJournal articleResearchpeer-review

The use of 5-aminosalicylate for patients with Crohn’s disease in a prospective European inception cohort with 5 years follow-up: an Epi-IBD study

for the Epi-IBD group, 26. Jul 2020, In : United European Gastroenterology Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

Total area of spontaneous portosystemic shunts independently predicts hepatic encephalopathy and mortality in liver cirrhosis

Baveno VI-SPSS group of the Baveno Cooperation, Jun 2020, In : Journal of Hepatology. 72, 6, p. 1140-1150

Research output: Contribution to journalJournal articleResearchpeer-review

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