IRS - Lillebælt Hospital, Research Unit of Clinical Microbiology (Vejle) – Research output

2023

Detection of Borrelia burgdorferi sensu lato DNA in cerebrospinal fluid samples following pre-enrichment culture

Leth, T. A., Nymark, A., Knudtzen, F. C., Larsen, S. L., Skov, M. N., Jensen, T. G., Bek-Thomsen, M., Jensen, H. B., Hovius, J. W., Skarphédinsson, S., Møller, J. K. & Andersen, N. S., May 2023, In: Ticks and Tick-borne Diseases. 14, 3, 7 p., 102138.

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POCT urine dipstick versus central laboratory analyses: Diagnostic performance and logistics in the medical emergency department

Andersen, E. S., Østergaard, C., Röttger, R., Christensen, A. F., Brandslund, I. & Brasen, C. L., Jan 2023, In: Clinical Biochemistry. 111, p. 17-25

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Transplacental transfer of SARS-CoV-2 antibodies: a cohort study

Nielsen, S. Y., Petersen, L. H., Murra, M., Hvidman, L., Helmig, R. B., Møller, J. K., Khalil, M. R., Kirkeby, M. & Henriksen, T. B., Mar 2023, In: European Journal of Clinical Microbiology and Infectious Diseases. 42, 3, p. 277-285

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2022

An intervention in general practice to improve the management of Lyme borreliosis in Denmark

Knudtzen, F. C., Jensen, T. G., Andersen, N. S., Johansen, I. S., Hovius, J. W. & Skarphédinsson, S., 1. Jun 2022, In: European Journal of Public Health. 32, 3, p. 436-442

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Azole resistance in Aspergillus fumigatus: The first 2-year's Data from the Danish National Surveillance Study, 2018–2020

Risum, M., Hare, R. K., Gertsen, J. B., Kristensen, L., Rosenvinge, F. S., Sulim, S., Abou-Chakra, N., Bangsborg, J., Røder, B. L., Marmolin, E. S., Astvad, K. M. T., Pedersen, M., Dzajic, E., Andersen, S. L. & Arendrup, M. C., Apr 2022, In: Mycoses. 65, 4, p. 419-428

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Bacteremia with Anaerobic Bacteria and Association with Colorectal Cancer: A Population-based Cohort Study

Justesen, U. S., Nielsen, S. L., Jensen, T. G., Dessau, R. B., Møller, J. K., Coia, J. E., Andersen, S. L., Pedersen, C. & Gradel, K. O., 14. Nov 2022, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75, 10, p. 1747-1753

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Discriminating between Lyme neuroborreliosis and other central nervous system infections by use of biomarkers CXCL13 and IL-6

Leth, T. A., Dessau, R. B. & Møller, J. K., Sep 2022, In: Ticks and Tick-borne Diseases. 13, 5, 11 p., 101984.

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Establishment of a digital PCR method for detection of Borrelia burgdorferi sensu lato complex DNA in cerebrospinal fluid

Leth, T. A., Joensen, S. M., Bek-Thomsen, M. & Møller, J. K., Dec 2022, In: Scientific Reports. 12, 12 p., 19991.

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Impact of C-reactive protein and albumin levels on short, medium, and long term mortality in patients with diffuse large B-cell lymphoma

Gradel, K. O., Larsen, T. S., Frederiksen, H., Vinholt, P. J., Iachina, M., Póvoa, P., Zampieri, F. G., Nielsen, S. L., Dessau, R. B., Møller, J. K., Jensen, T. G., Chen, M., Coia, J. E. & Jelicic, J., 2022, In: Annals of Medicine. 54, 1, p. 713-722

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Invasive group B Streptococcus strains and clinical characteristics in Danish infants from 1999 to 2009

Andersen, M., Smith, B., Murra, M., Nielsen, S. Y., Slotved, H. C. & Henriksen, T. B., 28. Sep 2022, In: Frontiers in Microbiology. 13, 10 p., 1001953.

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Maternal age and body mass index as risk factors for rectovaginal colonization with group B streptococci

Khalil, M. R. E., Hartvigsen, C. M., Bak Thorsen, P., Møller, J. K. & Uldbjerg, N., 10. Sep 2022, (E-pub ahead of print) In: International Journal of Gynecology & Obstetrics.

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One Day in Denmark: Comparison of Phenotypic and Genotypic Antimicrobial Susceptibility Testing in Bacterial Isolates From Clinical Settings

Rebelo, A. R., Bortolaia, V., Leekitcharoenphon, P., Hansen, D. S., Nielsen, H. L., Ellermann-Eriksen, S., Kemp, M., Røder, B. L., Frimodt-Møller, N., Søndergaard, T. S., Coia, J. E., Østergaard, C., Westh, H. & Aarestrup, F. M., 10. Jun 2022, In: Frontiers in Microbiology. 13, 12 p., 804627.

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One Day in Denmark: Nationwide point-prevalence survey of human bacterial isolates and comparison of classical and whole-genome sequence-based species identification methods

Rebelo, A. R., Ibfelt, T., Bortolaia, V., Leekitcharoenphon, P., Hansen, D. S., Nielsen, H. L., Ellermann-Eriksen, S., Kemp, M., Røder, B. L., Frimodt-Møller, N., Søndergaard, T. S., Coia, J. E., Østergaard, C., Pedersen, M., Westh, H. & Aarestrup, F. M., Feb 2022, In: PLOS ONE. 17, 2, 17 p., e0261999.

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Polymerase chain reaction for Group B Streptococci (GBS) at labor highly correlates with vaginal GBS load

Khalil, M. R., Bak Thorsen, P., Møller, J. K. & Uldbjerg, N., Dec 2022, In: The Journal of Maternal-Fetal & Neonatal Medicine. 35, 25, p. 6782-6786

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Prevalence and Mortality of Infective Endocarditis in Community-Acquired and Healthcare-Associated Staphylococcus aureus Bacteremia: A Danish Nationwide Registry-Based Cohort Study

Østergaard, L., Voldstedlund, M., Bruun, N. E., Bundgaard, H., Iversen, K., Køber, N., Dahl, A., Chamat-Hedemand, S., Petersen, J. K., Jensen, A. D., Christensen, J. J., Rosenvinge, F. S., Jarløv, J. O., Moser, C., Andersen, C. Ø., Coia, J., Marmolin, E. S., Søgaard, K. K., Lemming, L., Køber, L., & 1 othersFosbøl, E. L., Dec 2022, In: Open Forum Infectious Diseases. 9, 12, 9 p., ofac647.

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Reduction of intrapartum antibiotic prophylaxis by combining risk factor assessment with a rapid bedside intrapartum polymerase chain reaction testing for group B streptococci

Hartvigsen, C. M., Nielsen, S. Y., Møller, J. K. & Khalil, M. R., May 2022, In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 272, p. 173-176

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Sentinel surveillance and epidemiology of Clostridioides difficile in Denmark, 2016 to 2019

Persson, S., Nielsen, H. L., Coia, J., Engberg, J. H., Scharvik Olesen, B., Engsbro, A. L., Petersen, A. M., Holt, H., Lemming, L. E., Marmolin, E. S., Søndergaard, T. S., Andersen, L. P., Frid Jensen, M. B., Wiuff, C., Sørensen, G., Holtsmark Nielsen, S. & Nielsen, E. M., Dec 2022, In: Eurosurveillance. 27, 49, 9 p., pii=2200244.

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Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination

Pedersen, R. M., Bang, L. L., Madsen, L. W., Sydenham, T. V., Johansen, I. S., Jensen, T. G., Justesen, U. S. & Andersen, T. E., 1. Jun 2022, In: Emerging Infectious Diseases. 28, 6, p. 1274-1275

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Temporal Changes, Patient Characteristics, and Mortality, According to Microbiological Cause of Infective Endocarditis: A Nationwide Study

Østergaard, L., Voldstedlund, M., Bruun, N. E., Bundgaard, H., Iversen, K., Køber, N., Christensen, J. J., Rosenvinge, F. S., Jarløv, J. O., Moser, C., Andersen, C. Ø., Coia, J., Marmolin, E. S., Søgaard, K. K., Lemming, L., Køber, L. & Fosbøl, E. L., 16. Aug 2022, In: Journal of the American Heart Association. 11, 16, 17 p., e025801.

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The diagnostic value of serum Borrelia burgdorferi antibodies and seroconversion after Lyme neuroborreliosis: a nationwide observational study

Tetens, M. M., Dessau, R., Ellermann-Eriksen, S., Andersen, N. S., Jørgensen, C. S., Østergaard, C., Bodilsen, J., Damgaard, D. F., Bangsborg, J., Nielsen, A. C., Møller, J. K., Omland, L. H., Obel, N. & Lebech, A-M., Nov 2022, In: Clinical Microbiology and Infection. 28, 11, p. 1500.e1-1500.e6

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2021

A comparison of predictors for mortality and bacteraemia in patients suspected of infection

Andreassen, S., Møller, J. K., Eliakim-Raz, N., Lisby, G. & Ward, L., Aug 2021, In: BMC Infectious Diseases. 21, 10 p., 864.

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Assessment of the Risk of Psychiatric Disorders, Use of Psychiatric Hospitals, and Receipt of Psychiatric Medication Among Patients With Lyme Neuroborreliosis in Denmark

Tetens, M. M., Haahr, R., Dessau, R. B., Krogfelt, K. A., Bodilsen, J., Andersen, N. S., Møller, J. K., Roed, C., Christiansen, C. B., Ellermann-Eriksen, S., Bangsborg, J. M., Hansen, K., Andersen, C. Ø., Lebech, A-M., Obel, N. & Omland, L. H., 1. Feb 2021, In: JAMA Psychiatry. 78, 2, p. 177-186

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Daily monitoring of viral load measured as SARS-CoV-2 antigen and RNA in blood, IL-6, CRP and complement C3d predicts outcome in patients hospitalized with COVID-19

Brasen, C. L., Christensen, H., Olsen, D. A., Kahns, S., Andersen, R. F., Madsen, J. B., Lassen, A., Kierkegaard, H., Jensen, A., Sydenham, T. V., Madsen, J. S., Møller, J. K. & Brandslund, I., 25. Nov 2021, In: Clinical Chemistry and Laboratory Medicine. 59, 12, p. 1988-1997

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Danish Whole-Genome-Sequenced Candida albicans and Candida glabrata Samples Fit into Globally Prevalent Clades

Szarvas, J., Rebelo, A. R., Bortolaia, V., Leekitcharoenphon, P., Hansen, D. S., Nielsen, H. L., Nørskov-Lauritsen, N., Kemp, M., Røder, B. L., Frimodt-Møller, N., Søndergaard, T. S., Coia, J., Østergaard, C., Westh, H. & Aarestrup, F. M., 12. Nov 2021, In: Journal of Fungi. 7, 11, 962.

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Electronic reporting of diagnostic laboratory test results from all healthcare sectors is a cornerstone of national preparedness and control of COVID-19 in Denmark

Schønning, K., Dessau, R. B., Jensen, T. G., Thorsen, N. M., Wiuff, C., Nielsen, L., Gubbels, S., Denwood, M., Thygesen, U. H., Christensen, L. E., Møller, C. H., Møller, J. K., Ellermann-Eriksen, S., Østergaard, C., Lam, J. U. H., Abushalleeh, N., Meaidi, M., Olsen, S., Mølbak, K. & Voldstedlund, M., Jul 2021, In: APMIS. 129, 7, p. 438-451

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Improved diagnostics of infectious diseases in emergency departments: a protocol of a multifaceted multicentre diagnostic study

Skjøt-Arkil, H., Heltborg, A., Lorentzen, M. H., Cartuliares, M. B., Hertz, M. A., Graumann, O., Rosenvinge, F. S., Petersen, E. R. B., Østergaard, C., Laursen, C. B., Skovsted, T. A., Posth, S., Chen, M. & Mogensen, C. B., 30. Sep 2021, In: BMJ Open. 11, 9, 10 p., e049606.

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Pitfalls in Diagnosing Urinary Tract Infection in Children below the Age of 2: Suprapubic Aspiration vs Clean-Catch Urine Sampling

Breinbjerg, A., Mohamed, L., Yde Nielsen, S., Rittig, S., Tullus, K. & Kamperis, K., Dec 2021, In: The Journal of Urology. 206, 6, p. 1482-1489

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Prediction of risk of acquiring urinary tract infection during hospital stay based on machine-learning: A retrospective cohort study

Møller, J. K., Sørensen, M. & Hardahl, C., 31. Mar 2021, In: PLOS ONE. 16, 3 , 16 p., e0248636.

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Quantifying SARS-CoV-2 nucleocapsid antigen in oropharyngeal swabs using single molecule array technology

Olsen, D. A., Brasen, C. L., Kahns, S., Madsen, J. B., Kierkegaard, H., Christensen, H., Jensen, A., Sydenham, T. V., Møller, J. K., Madsen, J. S. & Brandslund, I., Dec 2021, In: Scientific Reports. 11, 8 p., 20323.

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SARS-CoV-2 viral load as a predictor for disease severity in outpatients and hospitalised patients with COVID-19: A prospective cohort study

Knudtzen, F. C., Jensen, T. G., Lindvig, S. O., Rasmussen, L. D., Madsen, L. W., Hoegh, S. V., Bek-Thomsen, M., Laursen, C. B., Nielsen, S. L. & Johansen, I. S., 12. Oct 2021, In: PLOS ONE. 16, 10, 14 p., e0258421.

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Severe antibody-mediated transfusion-related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non-transfused male blood donor

Agergaard, C. N., Haunstrup, T. M., Fjordside, A. L., Baech, J., Steffensen, R. & Nielsen, K. R., Jun 2021, In: Clinical Case Reports. 9, 6, 4 p., e03818.

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The performance of GeneXpert® PCR assay in detecting group B streptococcus colonization at labor

Khalil, M. R., Moller, J. K. & Nielsen, S. Y., 15. Jun 2021, In: Clinical and Experimental Obstetrics and Gynecology. 48, 3, p. 661-664

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The serotype distribution of Streptococcus agalactiae (GBS) carriage isolates among pregnant women having risk factors for early-onset GBS disease: a comparative study with GBS causing invasive infections during the same period in Denmark

Slotved, H-C., Møller, J. K., Khalil, M. R. & Nielsen, S. Y., Dec 2021, In: BMC Infectious Diseases. 21, 8 p., 1129.

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Update 2016-2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective

Risum, M., Astvad, K., Johansen, H. K., Schonheyder, H. C., Rosenvinge, F., Knudsen, J. D., Hare, R. K., Datcu, R., Roder, B. L., Antsupova, V. S., Kristensen, L., Gertsen, J. B., Moller, J. K., Dzajic, E., Sondergaard, T. S. & Arendrup, M. C., 19. Jun 2021, In: Journal of Fungi. 7, 6, 16 p., 491.

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2020

A Chlamydia trachomatis 23S rRNA G1523A variant escaping detection in the Aptima Combo 2 assay (Hologic) was widespread across Denmark in July–September 2019

Hadad, R., Jensen, J. S., Westh, H., Grønbæk, I., Schwartz, L. J., Nielsen, L., Vang, T. M., Nielsen, R., Weinreich, L. S., Skov, M. N., Olsen, M., Møller, J. K., Kolmos, B., Unemo, M. & Hoffmann, S., Jun 2020, In: APMIS. 128, 6, p. 440-444

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A comparison of GenomEra® GBS PCR and GeneXpert ® GBS PCR assays with culture of GBS performed with and without broth pre-enrichment

Nielsen, S. Y., Møller, J. K. & Khalil, M. R., 1. Oct 2020, In: European Journal of Clinical Microbiology and Infectious Diseases. 39, 10, p. 1945-1950

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Associations between blood cultures after surgery for colorectal cancer and long-term oncological outcomes

Watt, S. K., Fransgaard, T., Degett, T. H., Thygesen, L. C., Benfield, T., Knudsen, J. D., Fuursted, K., Jensen, T. G., Dessau, R., Schønheyder, H. C., Møller, J. K. & Gögenur, I., Feb 2020, In: British Journal of Surgery. 107, 3, p. 310-315

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Carryover issues with UF-5000 urine flow cytometry: How did we miss it?

Andersen, E. S., Brasen, C. L., Christensen, A. F., Østergaard, C. & Brandslund, I., 26. Mar 2020, In: Clinical Chemistry and Laboratory Medicine. 58, 4, p. e120-e122

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Changes in Lyme neuroborreliosis incidence in Denmark, 1996 to 2015

Tetens, M. M., Haahr, R., Dessau, R. B., Krogfelt, K. A., Bodilsen, J., Andersen, N. S., Møller, J. K., Roed, C., Christiansen, C. B., Ellermann-Eriksen, S., Bangsborg, J. M., Hansen, K., Benfield, T. L., Andersen, C. Ø., Obel, N., Omland, L. H. & Lebech, A. M., Nov 2020, In: Ticks and Tick-borne Diseases. 11, 6, 6 p., 101549.

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Clinical experiences with a new system for automated hand hygiene monitoring: A prospective observational study

Iversen, A. M., Kavalaris, C. P., Hansen, R., Hansen, M. B., Alexander, R., Kostadinov, K., Holt, J., Kristensen, B., Knudsen, J. D., Møller, J. K. & Ellermann-Eriksen, S., May 2020, In: American Journal of Infection Control. 48, 5, p. 527-533

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Commercial bacterial and fungal broad-range PCR (Micro-Dx™) used on culture-negative specimens from normally sterile sites: diagnostic value and implications for antimicrobial treatment

Marbjerg, L. H., Holzknecht, B. J., Dargis, R., Dessau, R. B., Nielsen, X. C. & Christensen, J. J., Jun 2020, In: Diagnostic Microbiology and Infectious Disease. 97, 2, 6 p., 115028.

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Improvement of selection of pregnant women for intrapartum polymerase chain reaction screening for vaginal Group B Streptococci (GBS) colonization by adding GBS urine screening at 35–37 weeks of pregnancy

Khalil, M. R., Uldbjerg, N., Thorsen, P. B. & Møller, J. K., 1. Oct 2020, In: International Journal of Gynecology and Obstetrics. 151, 1, p. 124-127

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Investigation of possible clonal transmission of carbapenemase-producing Klebsiella pneumoniae complex member isolates in Denmark using core genome MLST and National Patient Registry Data

Hammerum, A. M., Lauridsen, C. A. S., Blem, S. L., Roer, L., Hansen, F., Henius, A. E., Holzknecht, B. J., Søes, L., Andersen, L. P., Røder, B. L., Justesen, U. S., Østergaard, C., Søndergaard, T., Dzajic, E., Wang, M., Fulgsang-Damgaard, D., Møller, K. L., Porsbo, L. J. & Hasman, H., May 2020, In: International Journal of Antimicrobial Agents. 55, 5, 105931.

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Longitudinal trajectory patterns of plasma albumin and C-reactive protein levels around diagnosis, relapse, bacteraemia, and death of acute myeloid leukaemia patients

Gradel, K. O., Póvoa, P., Garvik, O. S., Vinholt, P. J., Nielsen, S. L., Jensen, T. G., Chen, M., Dessau, R. B., Møller, J. K., Coia, J. E., Ljungdalh, P. S., Lassen, A. T. & Frederiksen, H., 24. Mar 2020, In: BMC Cancer. 20, 13 p., 249.

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Molecular characterization of Danish ESBL/AmpC-producing Klebsiella pneumoniae from bloodstream infections, 2018

Hansen, S. K., Kaya, H., Roer, L., Hansen, F., Skovgaard, S., Justesen, U. S., Hansen, D. S., Andersen, L. P., Knudsen, J. D., Røder, B. L., Østergaard, C., Søndergaard, T., Dzajic, E., Wang, M., Samulioniené, J., Hasman, H. & Hammerum, A. M., Sep 2020, In: Journal of Global Antimicrobial Resistance. 22, p. 562-567

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Risk-based screening and intrapartum group B streptococcus polymerase chain reactionresults reduce use of antibiotics during labour

Rottbøll Rosenberg, L., Normann, A. K., Henriksen, B., Fenger-Grøn, J., Møller, J. K. & Khalil, M. R., 20. Oct 2020, In: Danish Medical Journal. 67, 11, 7 p., A06200460.

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Risk of neurological disorders in patients with European Lyme neuroborreliosis. A nationwide population-based cohort study

Haahr, R., Tetens, M. M., Dessau, R. B., Krogfelt, K. A., Bodilsen, J., Andersen, N. S., Møller, J. K., Roed, C., Christiansen, C. B., Ellermann-Eriksen, S., Bangsborg, J. M., Hansen, K., Benfield, T. L., Østergaard Andersen, C., Obel, N., Lebech, A-M. & Omland, L. H., 12. Sep 2020, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 71, 6, p. 1511-1516

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Surveillance of OXA-244-producing Escherichia coli and epidemiologic investigation of cases, Denmark, January 2016 to August 2019

Hammerum, A. M., Porsbo, L. J., Hansen, F., Roer, L., Kaya, H., Henius, A., Møller, K. L., Justesen, U. S., Søes, L., Røder, B. L., Thomsen, P. K., Wang, M., Søndergaard, T. S., Holzknecht, B. J., Østergaard, C., Kjerulf, A., Kristensen, B. & Hasman, H., 7. May 2020, In: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 25, 18, 9 p., pii=1900742.

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Urine dipstick for predicting intrapartum recto-vaginal colonisation by group B streptococci

Khalil, M. R., Uldbjerg, N., Bak Thorsen, P. & Møller, J. K., 1. Feb 2020, In: Danish Medical Journal. 67, 2, 4 p., A08190466.

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Wastewater treatment plant workers’ exposure and methods for risk evaluation of their exposure

Lu, R., Frederiksen, M. W., Uhrbrand, K., Li, Y., Østergaard, C. & Madsen, A. M., 1. Dec 2020, In: Ecotoxicology and Environmental Safety. 205, 10 p., 111365.

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IRS - Lillebælt Hospital, Research Unit of Clinical Microbiology (Vejle)

Research output

Search results